Elizabeth T Helfrich, Camilo M Saraiva, James M Chimiak, Matias Chimiak
INTRODUCTION: Minors have been scuba diving for decades, and while the initial concerns about potential long-term complications related to bone development appear to be unfounded, the incidence of scuba diving injuries among them has been poorly studied. METHODS: We reviewed 10,159 cases recorded in the DAN Medical Services call centre database from 2014 through 2016 and identified 149 cases of injured divers younger than 18 years. Records were analysed for case categorisation on the most common dive injuries...
March 31, 2023: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
Jimei Chi, Meng Su, Bingjie Xue, Lijun Cheng, Zewei Lian, Yang Yun, Xu Yang, Xue Wang, Hongfei Xie, Huadong Wang, Yuan Wang, Jie Du, Yanlin Song
With the demand for point-of-care testing (POCT) in cardiovascular diseases, the detection of biomarkers in trace blood samples is of great significance in emergency medicine settings. Here, we demonstrated an all-printed photonic crystal microarray for POCT of protein markers (named "P4 microarray"). The paired nanobodies were printed as probes to target the soluble suppression of tumorigenicity 2 (sST2) as a certified cardiovascular protein marker. Benefiting from photonic crystal-enhanced fluorescence and integrated microarrays, quantitative detection of sST2 is 2 orders of magnitude lower than that of a traditional fluorescent immunoassay...
March 26, 2023: ACS Sensors
Edward Sisco, Meghan Appley
Public health, public safety, and forensic science personnel continue to face the emergence of new compounds into the drug market. While focus is often put on the detection of new analogs of known illicit drugs, monitoring the changes in cutting agents and other compounds can be equally as important. Over the last year, near real-time monitoring of the drug supply in Maryland has been completed through a public health-public safety partnership whereby residue from suspected drug packaging or used paraphernalia is collected and analyzed...
March 26, 2023: Journal of Forensic Sciences
Chirag Bhat, Krishan Yadav, Hans Rosenberg
No abstract text is available yet for this article.
March 26, 2023: CJEM
Domonkos Kiss, Gábor Fritúz, Enikő Kovács, Csaba Diószeghy
Survival of in-hospital cardiac arrests is still as low as 15-35%. Healthcare workers should closely monitor patients' vital signs, notice any deterioration, and initiate the necessary actions to prevent cardiac arrest. The introduction of early warning sign protocols (including the monitoring of respiratory rate, oxygen saturation, pulse, blood pressure, consciousness, etc.) can improve the recognition of periarrest patients during hospital stay. However, when a cardiac arrest occurs, healthcare workers should also be able to work in team and follow the relevant protocols delivering good quality chest compressions and early defibrillation...
March 26, 2023: Orvosi Hetilap
Bettina Nagy, Boldizsár Kiss, Alexandra Fekete-Győr, Ádám Pál-Jakab, Enikő Kovács, Endre Zima
Since the onset of the coronavirus disease, infection-related mortality has been tracked worldwide and the number of deaths caused by the virus is counted daily. The coronavirus pandemic has not only transformed our daily life, but reorganized the whole healthcare system. In response to the increased demand for hospital admissions, leaders in different countries have implemented a number of emergency actions. The restructuring has had both direct and indirect negative effects on the epidemiology of sudden cardiac death, the willingness of lay rescuer to give cardiopulmonary resuscitation and the use of automated external defibrillators, but these negative effects vary widely across continents and countries...
April 2, 2023: Orvosi Hetilap
Katrina F Hurley, Eleanor A Fitzpatrick, Jianling Xie, Sarah Urquhart, Ken J Farion, Serge Gouin, Suzanne Schuh, Naveen Poonai, Stephen Freedman
BACKGROUND: To improve our understanding of adherence to discharge medications in the ED and within research trials, we sought to quantify medication adherence and identify predictors thereof in children with acute gastroenteritis (AGE). METHODS: We conducted a secondary analysis of a randomized trial of twice daily probiotic for 5 days. The population included previously healthy children aged 3-47 months with AGE. The primary outcome was patient-reported adherence to the treatment regimen, defined a priori as having received >70% of the prescribed doses...
March 26, 2023: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
Menachem Laufer
In recent years, we witnessed significant changes in the way we diagnose prostate cancer and the options for management of low risk localized prostate cancer. This review discusses today's approach to men with elevated PSA. The use of biomarkers and or prostate MRI is strongly recommended prior to the decision on a biopsy. Following a suspicious finding in MRI the best approach is MRI-guided biopsy. Traditionally, biopsies are performed transrectally but the emerging transperineal biopsy has considerable advantage...
March 2023: Harefuah
Nawaf Alammari, Mohammed Alshalhoub, Mohanad Aleeban
BACKGROUND Deep vein thrombosis (DVT) is a potentially fatal condition that occurs in 100 persons per 100 000 population, and accounts for 60 000 deaths per year in the United States, making its evaluation and diagnosis essential. Diagnosing DVT can be challenging due to symptom variations between patients. There are no previous reports of DVT patients presenting with foot drop in the literature. Therefore, the purpose of this case report is to present an unusual presentation of DVT in a middle-aged man with no clearly identifiable risk factors for DVT...
March 26, 2023: American Journal of Case Reports
Ming Chuen Chong, Melissa K Sharp, Susan M Smith, Michelle O'Neill, Máirín Ryan, Rosarie Lynch, Kamal R Mahtani, Barbara Clyne
BACKGROUND: Clinical guidelines should be based on a thorough evaluation of the evidence and generally include a rating of the quality of evidence and assign a strength to recommendations. Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidance warns against making strong recommendations when the certainty of the evidence is low or very low, but has identified five paradigmatic situations (e.g. life-threatening situations) where this may be justified. AIMS AND OBJECTIVES: We aimed to characterize the strength of recommendations and certainty of the evidence in Irish National Clinical Guidelines using the GRADE approach...
March 25, 2023: BMC Medical Research Methodology
Andrea Sonaglioni, Antonella Caminati, Margherita Re, Davide Elia, Roberta Trevisan, Alberto Granato, Maurizio Zompatori, Michele Lombardo, Sergio Harari
During the last decade, the CHA2 DS2 -VASc score has been used for stratifying the mortality risk in both atrial fibrillation (AF) and non-AF patients. However, no previous study considered this score as a prognostic indicator in non-AF patients with mild-to-moderate idiopathic pulmonary fibrosis (IPF). All consecutive non-AF patients with mild-to-moderate IPF, diagnosed between January 2016 and December 2018 at our Institution, entered this study. All patients underwent physical examination, blood tests, spirometry, high-resolution computed tomography and transthoracic echocardiography...
March 25, 2023: Internal and Emergency Medicine
Valeria Raparelli, Roberto Cangemi, Stefania Basili
No abstract text is available yet for this article.
March 25, 2023: Internal and Emergency Medicine
Audrey A Keim, Ronna L Campbell, Aidan F Mullan, Megan L McElhinny, Jessica Monas, Alexander S Finch, Kellie L Mathis, Rachel A Lindor
STUDY OBJECTIVE: Stercoral colitis is inflammation of the bowel wall caused by fecal impaction. Despite reported high morbidity and risk of perforation, little research assessing outcomes is available. This study characterizes the presentation, management, and outcomes of emergency department patients with stercoral colitis. METHODS: We performed a retrospective chart review of ED patients with stercoral colitis identified on computed tomography (CT) scan. Of 814, 522 visits to multiple EDs across the US, 269 met the inclusion criteria...
March 23, 2023: Annals of Emergency Medicine
Aum R Patel, Melissa Dulcey, Nabil Abid, Melanie N Cash, Jordan Dailey, Marco Salemi, Carla Mavian, Amy Y Vittor
Mayaro virus (MAYV) is an emergent arthropod-borne virus that causes an acute febrile illness accompanied by arthralgia, similar to chikungunya virus. Increasing urbanization of MAYV outbreaks in the Americas has led to concerns for geographic expansion and spillover. Given the potential importance of this pathogen, we sought to fill critical gaps in knowledge regarding MAYV infectivity and geographic variation. This study describes the cytopathogenicity of MAYV in human dermal fibroblasts, human skeletal muscle satellite cells, human embryonic kidney cells (HEK), peripherally derived human macrophages, and Vero cells...
March 23, 2023: Acta Tropica
Mary Beth Spitznagel, John T Martin, Christopher Was, Alanna S G Updegraff, Meg Sislak, Lisa Wiborg, Christopher M Fulkerson, Michael P Twohig
OBJECTIVE: An acceptance and commitment training (ACT) educational program targeting reaction to difficult client interactions recently demonstrated efficacy in reducing burden transfer, stress, and burnout in veterinary healthcare teams. The current noninferiority trial compared effectiveness of the original program with a self-paced version. SAMPLE: Employees of 2 corporate veterinary groups were randomized to live (n = 128) or self-paced (124) conditions. The workshop and assessments were completed by 137 (55 live and 82 self-paced)...
March 22, 2023: Journal of the American Veterinary Medical Association
Ali Pourmand, Rashed AlRemeithi, Santiago Martinez, Cody Couperus, Maryann Mazer-Amirshahi, Jerry Yang, Quincy K Tran
BACKGROUND: With musculoskeletal back pain being one of the most common presentations in the emergency department, evidence-based management strategies are needed to address such complaints. Along with other medications, cyclobenzaprine is a muscle relaxant commonly prescribed for patients complaining of musculoskeletal pain, in particular, pain associated with muscle spasms. However, with recent literature questioning its efficacy, the role of cyclobenzaprine use in patients with musculoskeletal back pain remains unclear...
March 18, 2023: American Journal of Emergency Medicine
Junhyeok Ock, Dayeong Hong, Sojin Moon, Yong-Seok Park, Dong-Woo Seo, Joo Heung Yoon, Sung-Hoon Kim, Namkug Kim
BACKGROUND AND OBJECTIVES: Proper airway management during emergencies can prevent serious complications. However, cricothyroidotomy is challenging in patients with obesity. Since this technique is not performed frequently but at a critical time, the opportunity for trainees is rare. Simulators for these procedures are also lacking. Therefore, we proposed a realistic and interactive cricothyroidotomy simulator. METHODS: All anatomical structures were modeled based on computed tomography images of a patient with obesity...
March 12, 2023: Computer Methods and Programs in Biomedicine
Kevser Kübra Kırboğa, Ecir Uğur Küçüksille, Muhammet Emin Naldan, Mesut Işık, Oktay Gülcü, Emrah Aksakal
BACKGROUND AND PURPOSE: COVID-19, which emerged in Wuhan (China), is one of the deadliest and fastest-spreading pandemics as of the end of 2019. According to the World Health Organization (WHO), there are more than 100 million infectious cases worldwide. Therefore, research models are crucial for managing the pandemic scenario. However, because the behavior of this epidemic is so complex and difficult to understand, an effective model must not only produce accurate predictive results but must also have a clear explanation that enables human experts to act proactively...
March 18, 2023: Computer Methods and Programs in Biomedicine
Moniya Katyal, Rakshanda Singh, Ritu Mahajan, Anurekha Sharma, Ranjan Gupta, Neeraj K Aggarwal, Anita Yadav
Bacteria are considered mini chemical factories that help us in providing a wide range of products for various purposes. These days, bacterial cellulose is getting attention by researchers due to its quality, eco-friendly nature, and excellent physical-mechanical qualities. It is being used in the fabrication of nanocomposites. Its nanocomposites can be used in various industries, including medicine, food, leather, textiles, environment, electronics and cosmetics. This area of research is emerging and still in its infancy stage, as new applications are still coming up...
March 25, 2023: Biotechnology and Applied Biochemistry
Elena Succurro, Alessio Novella, Alessandro Nobili, Federica Giofrè, Franco Arturi, Angela Sciacqua, Francesco Andreozzi, Antonello Pietrangelo, Giorgio Sesti
Diabetes is an increasing global health burden with the highest prevalence (24.0%) observed in elderly people. Older diabetic adults have a greater risk of hospitalization and several geriatric syndromes than older nondiabetic adults. For these conditions, special care is required in prescribing therapies including anti- diabetes drugs. Aim of this study was to evaluate the appropriateness and the adherence to safety recommendations in the prescriptions of glucose-lowering drugs in hospitalized elderly patients with diabetes...
March 25, 2023: Internal and Emergency Medicine
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