Qi Liu, Junqiang Chen, Yu Lin, Jinjun Ye, Wenbin Shen, Honglei Luo, Baosheng Li, Wei Huang, Shihong Wei, Jibin Song, Yaohui Wang, Huanjun Yang, Songtao Lai, Hongcheng Zhu, Dashan Ai, Yun Chen, Jiaying Deng, Shengnan Hao, Kuaile Zhao
BACKGROUND: The efficacy of local therapy for patients with oligometastatic oesophageal squamous cell carcinoma is unclear. We aimed to assess the efficacy of local plus systemic therapy compared with systemic therapy alone in patients with oligometastatic oesophageal squamous cell carcinoma. METHODS: The ESO-Shanghai 13 trial was a randomised, open-label, multicentre, phase 2 trial. Patients (aged ≥18 years) were recruited from six hospitals in China with histological confirmation of oligometastatic oesophageal squamous cell carcinoma with a controlled primary tumour and one to four metastatic lesions...
November 16, 2023: Lancet. Gastroenterology & Hepatology