keyword
https://read.qxmd.com/read/38452696/smilax-china-l-polysaccharide-prevents-hfd-induced-nafld-by-regulating-hepatic-fat-metabolism-and-gut-microbiota
#21
JOURNAL ARTICLE
Wenkai Zhang, Longhui Yu, Qinru Yang, Jinfeng Zhang, Wenjing Wang, Xinru Hu, Jingen Li, Guodong Zheng
BACKGROUND: The increasing incidence of nonalcoholic fatty liver disease (NAFLD) has urged the development of new therapeutics. NAFLD is intimately linked to gut microbiota due to the hepatic portal system, and utilizing natural polysaccharides as prebiotics has become a prospective strategy for preventing NAFLD. Smilax china L. polysaccharide (SCP) possesses excellent hepatoprotective and anti-inflammatory activity. However, its protective effects on NAFLD remains unclear. PURPOSE: The goal of this study was to explore the protective effects of SCP on high-fat diet (HFD)-induced NAFLD mice by regulating hepatic fat metabolism and gut microbiota...
February 24, 2024: Phytomedicine
https://read.qxmd.com/read/38450794/comparison-of-continuous-24-hour-and-14-day-ecg-monitoring-for-the-detection-of-cardiac-arrhythmias-in-patients-with-ischemic-stroke-or-syncope
#22
JOURNAL ARTICLE
Wei-Cheng Chen, Yu-Lin Wu, Yu-Cheng Hsu, Jen-Te Hsu, Hung-Pin Tseng, Chao-Chin Chen, Meng-Hsiu Chiang, Ju-Feng Hsiao, See-Khong Chin, Ying-Li Huang, Meng-Huan Lei
BACKGROUND: Previous studies show that using 12-lead electrocardiogram (ECG) or 24-h ECG monitor for the detection of cardiac arrhythmia events in patients with stroke or syncope is ineffective. HYPOTHESIS: The 14-day continuous ECG patch has higher detection rates of arrhythmias compared with conventional 24-h ECG monitoring in patients with ischemic stroke or syncope. METHODS: This cross-sectional study of patients with newly diagnosed ischemic stroke or syncope received a 24-h ECG monitoring and 14-day continuous cardiac monitoring patch and the arrhythmia events were measured...
February 2024: Clinical Cardiology
https://read.qxmd.com/read/38439167/inappropriate-icd-classification-of-ventricular-fibrillation-as-sinus-tachycardia-what-is-the-etiology
#23
JOURNAL ARTICLE
Rafat Mahmood, Anil K Gehi
No abstract text is available yet for this article.
March 4, 2024: Journal of Cardiovascular Electrophysiology
https://read.qxmd.com/read/38431699/pregnancy-outcomes-in-patients-complicated-with-pre-excitation-syndrome
#24
JOURNAL ARTICLE
Kana Wang, Junguo Xin, Qing Hu, Xiaodong Wang, Haiyan Yu
INTRODUCTION: Pregnant women with pre-excitation syndrome are more likely to develop supraventricular tachycardia (SVT) during pregnancy and delivery, leading to an increased risk of adverse events. METHOD: This was a retrospective study of 309 pregnancies in 280 women (29 women had two pregnancies in this series) with pre-excitation syndrome who delivered at West China Second University Hospital from June 2011 to October 2021. All the 309 pregnant women with pre-excitation syndrome were divided into SVT and non-SVT groups to analyze the cardiac and obstetric complications...
March 2, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38424693/reduced-kinase-function-in-two-ultra-rare-tnni3k-variants-in-families-with-congenital-junctional-ectopic-tachycardia
#25
JOURNAL ARTICLE
Caroline Pham, Tamara T Koopmann, Jeffrey M Vinocur, Nico A Blom, Vivian Nogueira Silbiger, Kirti Mittal, Marianne Bootsma, Kaylin C A Palm, Sally-Ann B Clur, Daniela Q C M Barge-Schaapveld, Robert M Hamilton, Elisabeth M Lodder
Genetic missense variants in TNNI3K, encoding troponin-I interacting kinase, have been associated with dilated cardiomyopathy (DCM) and observed in families with supraventricular tachycardias (SVT). Previously, a family harboring the TNNI3K-c.1615A > G (p.Thr539Ala) variant presented with congenital junctional ectopic tachycardia (CJET), an arrhythmia that arises from the atrioventricular (AV) node and His bundle. However, this was a relatively small four-generational family with limited genetic testing (N = 3)...
February 29, 2024: Clinical Genetics
https://read.qxmd.com/read/38416160/-history-of-surgical-treatment-of-cardiac-arrhythmias-in-germany-surgical-treatment-of-ventricular-tachycardia-and-supraventricular-tachycardia-especially-pre-excitation-syndromes-wpw
#26
REVIEW
Helmut U Klein, Hans-Joachim Trappe, Günter Frank
The history of surgical treatment of ventricular tachycardias (VT) is short, lasting from 1978 until 1993. "Indirect procedures" with infarct scar resection were performed without electrophysiologic studies, whereas "direct procedures" consisted of either complete endocardial incisions ("encircling endocardial ventriculotomy") or large endocardial resections ("endocardial peel-off" technique) after precise epicardial and endocardial mapping procedures. In Germany, the first to report on intra-operative electrophysiologic mapping for VT treatment were Ostermeyer, Breithardt and Seipel in 1979...
February 28, 2024: Herzschrittmachertherapie & Elektrophysiologie
https://read.qxmd.com/read/38413418/incidence-of-fetal-arrhythmia-before-and-during-the-covid-19-pandemic-a-single-center-experience
#27
JOURNAL ARTICLE
Stefani Samples, Sheetal Patel, Simon Lee, Nina Gotteiner, Angira Patel
Fetal arrhythmias are rare and carry significant morbidity and mortality without appropriate treatment. Initial reports exist of fetal arrhythmia in the setting of maternal COVID-19 infection. Our study sought to evaluate incidence of fetal arrhythmia before and during the COVID-19 pandemic at our institution. This retrospective cohort study from a tertiary care fetal cardiac center utilized the institutional REDCap database to search fetal arrhythmia diagnostic codes. Medical records of mother-fetus dyads were reviewed and data were collected on diagnoses, gestational age, treatment regimen, and postnatal outcomes...
February 27, 2024: Pediatric Cardiology
https://read.qxmd.com/read/38408072/adherence-to-24-hour-integrated-activity-guidelines-among-infants-toddlers-and-preschool-children-in-singapore
#28
JOURNAL ARTICLE
Phaik Ling Quah, Benny Kai Guo Loo, Michael Yong Hwa Chia, Terence Buan Kiong Chua, Teresa Shu Zhen Tan, Poh Chong Chan, Kok Hian Tan
This study examined children's adherence to the Singapore Integrated 24-Hour Activity Guidelines for Early Childhood in infants, toddlers and preschoolers aged 0-6 years. A total of 901 caregivers, comprising 219 infants, 379 toddlers, and 303 preschoolers, provided information regarding their children's physical activity (PA), screen viewing time (SVT), and sleep durations on both weekdays and weekends. Meeting the 24-hour integrated activity guidelines was defined as follows: for infants ≥ 30 minutes per day of tummy time or floor-based play; zero SVT; total sleep of 14-17 hours per day for ages 0-3 months, 12-16 hours per day for ages 4-11 months; for toddlers ≥ 180 minutes of total PA per day; zero SVT under 2 years; <1 hour for ages 2 to less than 3 years; and a total sleep of 11-14 hours per day; for preschoolers ≥ 180 minutes of total PA per day; SVT <1 hour per day; total sleep of 10-13 hours per day for those aged 3-5 years, and 10-11 hours per day for 6-year-olds...
2024: PloS One
https://read.qxmd.com/read/38400822/the-risk-of-developing-splanchnic-vein-thrombosis-in-acute-pancreatitis-increases-3%C3%A2-days-after-symptom-onset-a-systematic-review-and-meta-analysis
#29
JOURNAL ARTICLE
Ruben Zsolt Borbély, Eszter Ágnes Szalai, Bryan Mangalath Philip, Dalma Dobszai, Brigitta Teutsch, Ádám Zolcsák, Dániel Sándor Veres, Bálint Erőss, Bálint Gellért, Péter Jenő Hegyi, Péter Hegyi, Nándor Faluhelyi
BACKGROUND: Splanchnic vein thrombosis is a complication of acute pancreatitis (AP) and is likely often underdiagnosed. OBJECTIVES: We aimed to understand the time course and risk factors of splanchnic vein thrombosis in the early phase of AP. METHODS: A systematic search was conducted using the PRISMA guidelines (PROSPERO registration CRD42022367578). Inclusion criteria were appropriate imaging techniques in adult AP patients, studies that reported splanchnic vein thrombosis data from the early phase, and reliable information on the timing of imaging in relation to the onset of pancreatitis symptoms or hospital admission...
February 24, 2024: United European Gastroenterology Journal
https://read.qxmd.com/read/38391875/superficial-venous-thrombosis-a-comprehensive-review
#30
REVIEW
Marco Mangiafico, Luca Costanzo
Superficial venous thrombosis (SVT), an inflammatory-thrombotic process of a superficial vein, is a relatively common event that may have several different underlying causes. This phenomenon has been generally considered benign, and its prevalence has been historically underestimated; the estimated incidence ranges from about 0.3 to 1.5 event per 1000 person-years, while the prevalence is approximately 3 to 11%, with different reports depending on the population studied. However, such pathology is not free of complications; indeed, it could extend to the deep circulation and embolize to pulmonary circulation...
February 19, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38385329/plain-language-summary-of-the-safety-and-effectiveness-of-etripamil-for-atrioventricular-nodal-dependent-supraventricular-tachycardia-the-rapid-study
#31
REVIEW
James E Ip, Bruce S Stambler, David B Bharucha, Annette Green
WHAT IS THIS SUMMARY ABOUT?: This is a plain language summary of a clinical research study called RAPID. The study looked at the potential for how safe and effective etripamil was at stopping an episode of rapid heartbeats in people with atrioventricularnodal-dependent supraventricular tachycardia (AV-node-dependent SVT). An episode is used to describe the period of time when a person experiences an abnormally very fast heartbeat. This was done by comparing an investigational drug called etripamil with a placebo, each administered via a rapidly acting nasal spray...
February 22, 2024: Future Cardiology
https://read.qxmd.com/read/38383981/prior-history-of-atrial-fibrillation-and-arrhythmic-outcomes-data-from-the-wearit-ii-prospective-registry
#32
JOURNAL ARTICLE
Ido Goldenberg, Arwa Younis, Scott McNitt, Helmut Klein, Ilan Goldenberg, Valentina Kutyifa
INTRODUCTION: Wearable cardioverter defibrillator (WCD) is utilized in patients with assumed but not yet confirmed risk for sudden cardiac death (SCD). Many of these patients also present with atrial fibrillation (AF). However, the rate of WCD-detected ventricular or atrial arrhythmia events in this specific high-risk cohort is not well understood. METHODS: In WEARIT-II, the cumulative probability of any sustained or nonsustained VT/VF (WCD-treated and nontreated), and atrial/supraventricular arrhythmias during WCD use was assessed using the Kaplan-Meier method by prior AF, with comparisons by the log-rank test...
February 21, 2024: Journal of Cardiovascular Electrophysiology
https://read.qxmd.com/read/38366222/the-impact-of-adverse-childhood-experiences-on-symptom-and-performance-validity-tests-among-a-multiracial-sample-presenting-for-adhd-evaluation
#33
JOURNAL ARTICLE
Christopher Gonzalez, John-Christopher A Finley, Elmma Khalid, Karen S Basurto, Hannah B VanLandingham, Lauren A Frick, Julia M Brooks, Rachael L Ellison, Devin M Ulrich, Jason R Soble, Zachary J Resch
OBJECTIVE: Adverse childhood experiences (ACEs) are commonly reported in individuals presenting for attention-deficit hyperactivity disorder (ADHD) evaluation. Performance validity tests (PVTs) and symptom validity tests (SVTs) are essential to ADHD evaluations in young adults, but extant research suggests that those who report ACEs may be inaccurately classified as invalid on these measures. The current study aimed to assess the degree to which ACE exposure differentiated PVT and SVT performance and ADHD symptom reporting in a multi-racial sample of adults presenting for ADHD evaluation...
February 14, 2024: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://read.qxmd.com/read/38358465/extensive-splanchnic-vein-thrombosis-after-sars-cov-2-vaccination-a-vascular-liver-disease-group-valdig-initiative
#34
JOURNAL ARTICLE
Raoel Maan, Mandy N Lauw, Loise China, David Patch, Anna Baiges, Juan Carlos Garcia-Pagan, Virginia Hernández-Gea, Marie-Noelle Hilleret, Eric T Tjwa, Ilias Kounis, Christophe Bureau, Baptiste Giguet, Alexandra Heurgué, Isabelle Ollivier-Hourmand, Xavier Causse, Filipe Nery, Ahad Eshraghian, Aurélie Plessier, Sarwa Darwish Murad
BACKGROUND AND AIMS: Since the introduction of SARS-CoV-2 vaccines, several cases of vaccine-induced immune thrombocytopenia and thrombosis (VITT) have been described, especially cerebral vein thrombosis. We aimed to retrospectively collect all new cases of acute onset first or recurrent splanchnic vein thrombosis (SVT) following a recent SARS-CoV-2 vaccination within the Vascular Liver Disease Group network. APPROACH AND RESULTS: New cases of SVT were identified from April 2021 to April 2022; follow-up was completed on December 31, 2022...
February 15, 2024: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://read.qxmd.com/read/38354834/splanchnic-vein-thrombosis-the-state-of-the-art-on-anticoagulant-treatment
#35
JOURNAL ARTICLE
Scott Custo, Emma Tabone, Alexia Aquilina, Alex Gatt, Nicoletta Riva
Splanchnic vein thrombosis (SVT) is a rare type of venous thromboembolism occurring within the splanchnic venous system. Portal vein thrombosis is the most common presentation, while Budd-Chiari syndrome is the least common. Liver cirrhosis and abdominal solid cancer are the main local risk factors for SVT, whereas myeloproliferative neoplasms are the predominant systemic risk factors. Signs and symptoms of SVT are nonspecific and include abdominal pain, gastrointestinal bleeding, and ascites. Asymptomatic SVT is not uncommon, and the majority would be detected incidentally on routine abdominal imaging performed for the follow-up of liver diseases and tumors...
February 14, 2024: Hämostaseologie
https://read.qxmd.com/read/38348921/cannon-a-wave-validation-as-a-diagnostic-tool-in-paroxysmal-supraventricular-tachycardias
#36
JOURNAL ARTICLE
David González-Casal, Alberto Pérez-Castellanos, Nina Soto Flores, Alejandro Carta-Bergaz, Esteban González-Torrecilla, Vanesa Bruña Fernández, Pablo Ávila, Felipe Atienza, Ángel Arenal, Jorge González-Panizo, Francisco Fernández-Avilés, José Angel Cabrera, Tomás Datino
OBJECTIVE: The presence of cannon A waves, the so called "frog sign", has traditionally been considered diagnostic of atrioventricular nodal re-entrant tachycardia (AVNRT). Nevertheless, it has never been systematically evaluated. The aim of this study is to assess the independent diagnostic utility of cannon A waves in the differential diagnosis of supraventricular tachycardias (SVTs). METHODS: We prospectively included 100 patients who underwent an electrophysiology (EP) study for SVT...
February 13, 2024: Pacing and Clinical Electrophysiology: PACE
https://read.qxmd.com/read/38336603/splanchnic-vein-thrombosis-in-necrotizing-pancreatitis-a-post-hoc-analysis-of-a-nationwide-prospective-cohort
#37
JOURNAL ARTICLE
Noor J Sissingh, Hester C Timmerhuis, Jesse V Groen, Mike J P de Jong, Marc G Besselink, Bas Boekestijn, Thomas L Bollen, Bert A Bonsing, Stefan A W Bouwense, Wouter L Hazen, Frederikus A Klok, Hjalmar C van Santvoort, Casper H J van Eijck, Robert C Verdonk, J Sven D Mieog, Jeanin E van Hooft
BACKGROUND: Treatment guidelines for splanchnic vein thrombosis in necrotizing pancreatitis are lacking due to insufficient data on the full clinical spectrum. METHODS: We performed a post-hoc analysis of a nationwide prospective necrotizing pancreatitis cohort. Multivariable analyses were used to identify risk factors and compare the clinical course of patients with and without SVT. RESULTS: SVT was detected in 97 of the 432 included patients (22%) (median onset: 4 days)...
January 29, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/38336198/resource-utilization-and-clinical-outcomes-in-infants-with-supraventricular-tachycardia-monitored-with-the-owlet-smartsock
#38
JOURNAL ARTICLE
Laura Silverstein, Nicholas Dreger, Omar Abu Anza, Shashank Behere
OBJECTIVES: To describe the prevalence of Owlet Smartsock (OSS) use in infants with supraventricular tachycardia (SVT), and associated demographic and clinical characteristics of users, and to analyze the association of OSS use on medical resource utilization and clinical outcomes from emergency department (ED) encounters for SVT. STUDY DESIGN: Single-center, retrospective cohort study of infants with confirmed SVT, from 2015 to 2022. OSS users and non-users were compared across clinical and demographic parameters...
February 7, 2024: Journal of Pediatrics
https://read.qxmd.com/read/38286245/local-v-a-index-for-the-differential-diagnosis-of-supraventricular-tachycardia
#39
JOURNAL ARTICLE
Benjamin Bouyer, Nicolas Derval, Thomas Pambrun, Romain Tixier, Marine Arnaud, Samuel Buliard, Rémi Chauvel, Hugo Marchand, Xavier Bouteiller, Kostantinos Vlachos, Ciro Ascione, Masaaki Yokoyama, Christopher Kowalewski, Mélèze Hocini, Pierre Jaïs, Frederic Sacher, Michel Haïssaguerre, Josselin Duchateau
BACKGROUND: Differentiating between atypical atrioventricular node re-entrant tachycardia (aAVNRT) and orthodromic reciprocating tachycardia (ORT) utilizing a septal accessory pathway is a complex challenge. OBJECTIVE: We introduce the "local VA index," a straightforward method based on signals from the coronary sinus (CS) catheter, to distinguish between these arrhythmias during tachycardia and entrainment. The V-A interval on the CS catheter is measured during tachycardia and entrainment, at the site of earliest atrial activity...
January 27, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://read.qxmd.com/read/38263537/genomic-classification-and-outcomes-of-young-patients-with-polycythemia-vera-and-essential-thrombocythemia-according-to-the-presence-of-splanchnic-vein-thrombosis-and-its-chronology
#40
JOURNAL ARTICLE
Marta Garrote, Mónica López-Guerra, Juan Carlos García-Pagán, Eduardo Arellano-Rodrigo, Francisca Ferrer-Marín, Juan Carlos Hernández-Boluda, Beatriz Bellosillo, Meritxell Nomdedeu, Virginia Hernández-Gea, Ana Triguero, Francesca Guijarro, José Álamo, Anna Baiges, Fanny Turon, Dolors Colomer, Francisco Cervantes, Alberto Alvarez-Larrán
To elucidate the role of splanchnic vein thrombosis (SVT) and genomic characteristics in prognosis and survival, we compared patients with polycythemia vera (PV) or essential thrombocythemia (ET) presenting SVT at diagnosis (n = 69, median age 43 years) or during follow-up (n = 21, median age 46 years) to a sex- and age-matched control group of PV/ET without SVT (n = 165, median age 48 years). The majority of patients presenting with SVT at diagnosis were classified as myeloproliferative neoplasm with heterozygous JAK2 mutation (87% of cases vs...
January 24, 2024: Annals of Hematology
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