Jesús A Velásquez, Richard M Burwick, Alyssa R Hersh, Jaime L Silva, Viviana Lenis, Yamile Bernal, Johanna Vargas, Catalina Valencia, Jorge H Gutiérrez, Francisco Edna, Juliana Trujillo, Mónica Rincón, Maria I Alvarez, Jorge E Tolosa
OBJECTIVES: Dysregulation of CD59 may lead to increased complement-mediated end-organ injury in preeclampsia. We sought to determine if soluble CD59 concentrations are altered in preeclampsia with severe features. STUDY DESIGN: Observational case-control study, which enrolled subjects prospectively from six centers in Colombia from 2015 to 2016. Cases had preeclampsia with severe features and controls were either healthy or had chronic hypertension, gestational hypertension, or preeclampsia without severe features...
October 14, 2020: Pregnancy Hypertension