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JOURNAL ARTICLE
Ayele Semachew Kasa, Victoria Traynor, Peta Drury
BACKGROUND: Despite the critical need, interventions aimed at frailty in sub-Saharan Africa are scarce, attributed to factors such as insufficient healthcare infrastructure, the pressing need to address infectious diseases, maternal and child health issues, and a general lack of awareness. Hence, the aim of this research was to develop, implement, and evaluate the effect of a nurse-led program on frailty and associated health outcomes in community-dwelling older individuals in Ethiopia...
April 30, 2024: BMC Geriatrics
#42
REVIEW
Caroline Bonareri Osoro, Eleanor Ochodo, Titus K Kwambai, Jenifer Akoth Otieno, Lisa Were, Caleb Kimutai Sagam, Eddy Johnson Owino, Simon Kariuki, Feiko O Ter Kuile, Jenny Hill
In October 2021, the WHO recommended the world's first malaria vaccine-RTS,S/AS01-to prevent malaria in children living in areas with moderate-to-high transmission in sub-Saharan Africa (SSA). A second malaria vaccine, R21/Matrix-M, was recommended for use in October 2023 and added to the WHO list of prequalified vaccines in December 2023. This study analysis assessed the country status of implementation and delivery strategies for RTS,S/AS01 by searching websites for national malaria policies, guidelines and related documents...
April 30, 2024: BMJ Global Health
#43
JOURNAL ARTICLE
Claude Bragard, Paula Baptista, Elisavet Chatzivassiliou, Francesco Di Serio, Paolo Gonthier, Josep Anton Jaques Miret, Annemarie Fejer Justesen, Alan MacLeod, Christer Sven Magnusson, Panagiotis Milonas, Juan A Navas-Cortes, Stephen Parnell, Roel Potting, Philippe Lucien Reignault, Emilio Stefani, Hans-Hermann Thulke, Antonio Vicent Civera, Jonathan Yuen, Lucia Zappalà, Richard Mally, Ewelina Czwienczek, Alex Gobbi, Júlia López Mercadal, Andrea Maiorano, Olaf Mosbach-Schulz, Marco Pautasso, Eugenio Rossi, Giuseppe Stancanelli, Sara Tramontini, Wopke Van der Werf
Following a request from the European Commission, the EFSA Panel on Plant Health performed a quantitative risk assessment for the EU of African Leucinodes species (Lepidoptera: Crambidae), which are fruit and shoot borers, especially of eggplant type fruit. The assessment focused on (i) potential pathways for entry, (ii) distribution of infested imports within EU, (iii) climatic conditions favouring establishment, (iv) spread and (v) impact. Options for risk reduction are discussed, but their effectiveness was not quantified...
April 2024: EFSA journal
#44
JOURNAL ARTICLE
Ghislain F Difouo, Franklin T Simo, Sévilor Kekeunou, Oscar R Fokou, Lyiong Giscard Ndoh, David Olson
The white-bellied pangolin Phataginus tricuspis (Rafinesque 1821) is a semiarboreal species occurring in tropical sub-Saharan Africa. It is the world's most trafficked African pangolin species based on volumes recorded in seizures. Reintroduction of confiscated live pangolins and ex-situ rearing are being explored worldwide as a conservation action. However, the husbandry of seized animals is challenging as the diet of the white-bellied pangolin is poorly known and little studied. We analyzed the stomach contents of dead white-bellied pangolins from two forest-savanna protected areas...
April 29, 2024: Zoo Biology
#45
JOURNAL ARTICLE
Euclides N M Sacomboio, Santo D Zua, Adelino T Tchivango, António D Pululu, Adilson C D Caumba, Adelina B M Paciência, Danilson V Sati, Sabina G Agostinho, Yolanda S Agostinho, Fernando G Mazanga, Neusa B Ntambo, Cruz S Sebastião, Joana P Paixão, Joana Morais
INTRODUCTION: Introduction: Malaria continues to be the leading cause of hospitalization and death in Angola, a country in sub- Saharan Africa. In 2023, in the first quarter, 2,744,682 cases were registered, and of these 2,673 patients died due to malaria disease. Previous studies have shown that the ABO blood group can affect the progression of malaria to severe conditions after P. falciparum infection, while the sickle cell gene offers relative protection. OBJECTIVE: We investigated changes in the blood count according to blood groups (ABO/Rh) and sickle cell trait in patients with malaria in Luanda, capital of Angola...
April 29, 2024: Malaria Journal
#46
JOURNAL ARTICLE
Nicholas Ekow Thomford, Tracy Kellermann, Robert Peter Biney, Charné Dixon, Samuel Badu Nyarko, Richmond Owusu Ateko, Martins Ekor, George B Kyei
BACKGROUND: Despite efforts made to reduce morbidity and mortality associated with malaria, especially in sub-Saharan Africa, malaria continues to be a public health concern that requires innovative efforts to reach the WHO-set zero malaria agenda. Among the innovations is the use of artemisinin-based combination therapy (ACT) that is effective against Plasmodium falciparum. Generic artemether-lumefantrine (AL) is used to treat uncomplicated malaria after appropriate diagnosis. AL is metabolized by the cytochrome P450 family of enzymes, such as CYP2B6, CYP3A4 and CYP3A5, which can be under pharmacogenetic influence...
April 29, 2024: Malaria Journal
#47
JOURNAL ARTICLE
Justus Uchenna Onu, Iorhen Akase, Justice Ohaka, Ibrahim Musa Kida
BACKGROUND: Despite modest efforts to study and document the complications that arise after acute treatment of patients with coronavirus disease, its ramifications and regional variations are yet to be clearly understood. Progress in sub-Saharan Africa, notably Nigeria, has been impeded by patient disengagement from care and insufficient or non-existent follow-up arrangements. The aim of this study was to describe the barriers and enablers for follow-up services after discharge from COVID-19 care pathway in Nigeria...
April 29, 2024: BMC Health Services Research
#48
JOURNAL ARTICLE
Haibo Gong, Shuai Zhang, Jinfa Dou, Jing Chen
BACKGROUND: Clinically, most patients with Kaposi's sarcoma (KS) are male, and several direct and indirect mechanisms may underlie this increased susceptibility in men, Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8), is considered to be the primary etiological agent responsible for KS. Thus, we propose the hypothesis that men are more susceptible to HHV-8 infection, leading to a higher incidence of Kaposi's sarcoma among males. A meta-analysis was conducted to evaluate the association between gender and HHV-8 seropositivity in the general population...
April 29, 2024: BMC Infectious Diseases
#49
Stewart Jennings, Andrew Challinor, Pete Smith, Jennie I Macdiarmid, Edward Pope, Sarah Chapman, Catherine Bradshaw, Heather Clark, Sylvia Vetter, Nuala Fitton, Richard King, Sithembile Mwamakamba, Tshilidzi Madzivhandila, Ian Mashingaidze, Christian Chomba, Masiye Nawiko, Bonani Nyhodo, Ndumiso Mazibuko, Precious Yeki, Pamela Kuwali, Alfred Kambwiri, Vivian Kazi, Agatha Kiama, Abel Songole, Helen Coskeran, Claire Quinn, Susannah Sallu, Andrew Dougill, Stephen Whitfield, Bill Kunin, Nalishebo Meebelo, Andrew Jamali, Dhaquirs Kantande, Prosper Makundi, Winfred Mbungu, Frank Kayula, Sue Walker, Sibongile Zimba, Joseph Hubert Galani Yamdeu, Ndashe Kapulu, Marcelo Valadares Galdos, Samuel Eze, Hemant Tripathi, Steven Sait, Stefan Kepinski, Emmanuel Likoya, Henry Greathead, Harriet Elizabeth Smith, Marcelin Tonye Mahop, Helen Harwatt, Maliha Muzammil, Graham Horgan, Tim Benton
No abstract text is available yet for this article.
April 29, 2024: Nature food
#50
JOURNAL ARTICLE
Jinseo Kim, Yun-Jung Eom, Soohyeon Ko, S V Subramanian, Rockli Kim
BACKGROUND: Access to health care remains suboptimal in low- and middle-income countries (LMICs) and continues to hinder survival in early childhood. We systematically assessed the association between problems accessing health care (PAHC) and under-five mortality (U5M). METHODS: Child mortality data on 724 335 livebirths came from the latest Demographic and Health Surveys of 50 LMICs (2013-2021). Reasons for PAHC were classified into three domains: 'money needed for treatment' (economic), 'distance to health facility' (physical), 'getting permission' or 'not wanting to go alone' (socio-cultural)...
April 29, 2024: Journal of Public Health
#51
JOURNAL ARTICLE
Benard Ohene Kwatia, Godfred Amewu, Christopher Boachie
Rising income inequality has recently garnered intensive attention owing to its significance in theory and practice. This has rendered the mechanism through which inequality can be understood, even from a microscopic perspective, to institute proper policies that curtail it important. We contribute to the literature by examining the effect of freedom on income inequality using data from 34 least-free and 18 most-free countries from 2000 to 2020 in Sub-Saharan Africa and Western Europe, respectively. A novel fixed-effects panel quantile regression econometric estimator was employed, and the findings showed a non-linear relationship between personal freedom and income inequality for both regions...
2024: PloS One
#52
(no author information available yet)
[This corrects the article DOI: 10.1093/geroni/igae031.].
2024: Innovation in Aging
#53
JOURNAL ARTICLE
Imelda Namagembe, Babu Karavadra, Lawrence Kazibwe, Joseph Rujumba, Noah Kiwanuka, Brandon Smith, Josaphat Byamugisha, Ashley Moffett, Tom Bashford, Annettee Nakimuli, Catherine E Aiken
BACKGROUND: Sub-Saharan Africa bears the burden of 70% of maternal deaths worldwide, of which ∼10% are attributable to hypertensive disorders of pregnancy, primarily complications of preeclampsia. In other global settings, outcomes of pregnancies affected by preeclampsia are improved with timely and effective medical care. OBJECTIVE: This study aimed to explore the perspectives of local health care professionals on how preeclampsia care is currently delivered in the study setting and what challenges they experience in providing prompt and safe care...
May 2024: AJOG global reports
#54
JOURNAL ARTICLE
Mitchel Okumu, James Mbaria, Joseph Gikunju, Paul Mbuthia, Vincent Madadi, Francis Ochola
Background: The present study investigated the efficacy of Conyza bonariensis, Commiphora africana, Senna obtusifolia, Warburgia ugandensis, Vernonia glabra, and Zanthoxylum usambarense against Bitis arietans venom (BAV), Naja ashei venom (NAV), and Naja subfulva venom (NSV). Methods: 40 extracts and fractions were prepared using n-hexane, dichloromethane, ethyl acetate, and methanol. In vitro efficacy against snake venom phospholipase A2 (svPLA2 ) was determined in 96-well microtiter and agarose-egg yolk coagulation assays...
2024: Frontiers in Pharmacology
#55
JOURNAL ARTICLE
Evelyne Kestelyn, Jennifer Ilo Van Nuil, Marie Michelle Umulisa, Grace Umutoni, Alice Uwingabire, Irith De Baetselier, Mireille Uwineza, Stephen Agaba, Tania Crucitti, Thérèse Delvaux, Janneke H H M van de Wijgert
BACKGROUND: The introduction of female-initiated drug-delivery methods, including vaginal rings, have proven to be a promising avenue to address sexually transmitted infections and unintended pregnancies, which disproportionally affects women and girls in sub-Saharan Africa. Efficient uptake of existing and new technologies such as vaginal rings requires in depth understanding of product adherence. This remains a major challenge as data on adherence to vaginal rings from African countries is limited...
2024: Frontiers in global women's health
#56
JOURNAL ARTICLE
Wyckliff Ngetich, George Karuoya Gitau, Tequiero Abuom Okumu, Gabriel Oluga Aboge, Daniel Muasya
BACKGROUND AND AIM: East Coast fever (ECF), caused by Theileria parva , is a devastating disease that causes significant economic losses to cattle production in sub-Saharan Africa. Prevention and control of ECF are challenging in pastoral settings due to inadequate epidemiological information. This study aimed to estimate the seroprevalence and risk factors associated with T. parva infection among calves in different production systems to help design appropriate control interventions...
March 2024: Veterinary World
#57
JOURNAL ARTICLE
Amynah Janmohamed, David Doledec, Romance Dissieka, Umu H Jalloh, Sugandh Juneja, Maguette Beye, Fatou Ndiaye, Theresia Jumbe, Melissa M Baker
BACKGROUND: Vitamin A deficiency (VAD) is a leading contributor to the poor health and nutrition of young children in sub-Saharan Africa. Funding constraints are compelling many countries to shift from longstanding campaigns to integrating vitamin A supplementation (VAS) into routine health services. We assessed child VAS coverage and associated factors for integrated delivery systems in Mozambique, Senegal, and Sierra Leone and for a campaign-based delivery strategy in Tanzania. METHODS: Data were obtained using representative household surveys administered to primary caregivers of N = 16,343 children aged 6-59 months (Mozambique: N = 1,659; Senegal: N = 7,254; Sierra Leone: N = 4,149; Tanzania: N = 3,281)...
April 27, 2024: BMC Public Health
#58
JOURNAL ARTICLE
F Orina, E Amukoye, C Bowyer, J Chakaya, D Das, G Devereux, R Dobson, U Dragosits, C Gray, R Kiplimo, M Lesosky, M Loh, H Meme, K Mortimer, A Ndombi, C Pearson, H Price, M Twigg, S West, S Semple
Carbon monoxide (CO) is a poisonous gas produced by incomplete combustion of carbon-based fuels that is linked to mortality and morbidity. Household air pollution from burning fuels on poorly ventilated stoves can lead to high concentrations of CO in homes. There are few datasets available on household concentrations of CO in urban areas of sub-Saharan African countries. CO was measured every minute over 24 hours in a sample of homes in Nairobi, Kenya. Data on household characteristics were gathered by questionnaire...
April 25, 2024: Environmental Pollution
#59
JOURNAL ARTICLE
Robert Muriuki, Maingi Ndichu, Samuel Githigia, Nicholas Svitek
Theileria parvacauses East Coast fever (ECF), one of the most important and lethal tick-borne diseases of cattle in sub-Saharan Africa. ECF is a considerable burden to the livestock industry, causing annual losses exceeding US $300 million. Currently, diagnosis of T. parva infections relies mainly on clinical signs, serology, and microscopic identification of parasites in either blood or lymph fluid samples. However, these tests might not indicate ongoing infection and lack the sensitivity to detect low-level infections...
April 25, 2024: International Journal for Parasitology
#60
JOURNAL ARTICLE
Mark Urassa, Milly Marston, Charles Mangya, Jacqueline Materu, Duplessis Elsabe, Kinung'hi Safari, Sophia Kagoye, Jim Todd, Ties Boerma
No abstract text is available yet for this article.
April 11, 2024: International Journal of Epidemiology
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