Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#21
JOURNAL ARTICLE
Saif Bushnaq, Ameer E Hassan, Adam Delora, Ali Kerro, Anita Datta, Rime Ezzeldin, Zuhair Ali, Tunmi Anwoju, Layla Nejad, Rene Silva, Yazan Diya Abualnadi, Zorain Mustafa Khalil, Mohamad Ezzeldin
BACKGROUND AND PURPOSE: Automated CTP postprocessing packages have been developed for managing acute ischemic stroke. These packages use image processing techniques to identify the ischemic core and penumbra. This study aimed to investigate the agreement of decision-making rules and output derived from RapidAI and Viz.ai software packages in early and late time windows and to identify predictors of inadequate quality CTP studies. MATERIALS AND METHODS: One hundred twenty-nine patients with acute ischemic stroke who had CTP performed on presentation were analyzed by RapidAI and Viz...
April 4, 2024: AJNR. American Journal of Neuroradiology
#22
JOURNAL ARTICLE
James L Shepherdson, Katie Hutchison, Dilan Wellalage Don, George McGillivray, Tae-Ik Choi, Carolyn A Allan, David J Amor, Siddharth Banka, Donald G Basel, Laura D Buch, Deanna Alexis Carere, Renée Carroll, Jill Clayton-Smith, Ali Crawford, Morten Dunø, Laurence Faivre, Christopher P Gilfillan, Nina B Gold, Karen W Gripp, Emma Hobson, Alexander M Holtz, A Micheil Innes, Bertrand Isidor, Adam Jackson, Panagiotis Katsonis, Leila Amel Riazat Kesh, Sébastien Küry, François Lecoquierre, Paul Lockhart, Julien Maraval, Naomichi Matsumoto, Julie McCarrier, Josephine McCarthy, Noriko Miyake, Lip Hen Moey, Andrea H Németh, Elsebet Østergaard, Rushina Patel, Kate Pope, Jennifer E Posey, Rhonda E Schnur, Marie Shaw, Elliot Stolerman, Julie P Taylor, Erin Wadman, Emma Wakeling, Susan M White, Lawrence C Wong, James R Lupski, Olivier Lichtarge, Mark A Corbett, Jozef Gecz, Charles M Nicolet, Peggy J Farnham, Cheol-Hee Kim, Marwan Shinawi
Pathogenic variants in multiple genes on the X chromosome have been implicated in syndromic and non-syndromic intellectual disability disorders. ZFX on Xp22.11 encodes a transcription factor that has been linked to diverse processes including oncogenesis and development, but germline variants have not been characterized in association with disease. Here, we present clinical and molecular characterization of 18 individuals with germline ZFX variants. Exome or genome sequencing revealed 11 variants in 18 subjects (14 males and 4 females) from 16 unrelated families...
February 5, 2024: American Journal of Human Genetics
#23
JOURNAL ARTICLE
Amy Jayas, Ajit K Sachdeva, Keith A Delman, Adam S Kabaker, Patrice Gabler Blair, Renee Overton, Douglas Grbic, Dorothy A Andriole
OBJECTIVE: To determine the extent to which U.S. Liaison Committee of Medical Education (LCME)-accredited medical schools chose to participate in piloting a national curricular resource, the American College of Surgeons/Association of Program Directors in Surgery/Association of Surgical Education Resident Prep Curriculum ("ACS-surgery-prep curriculum"), and implications of such participation for student access nationally to this resource. DESIGN: We examined the significance of school-level differences in ACS-surgery-prep curriculum pilot participation and student-level differences in curriculum access based on medical school attended in bivariate analysis...
January 28, 2024: Journal of Surgical Education
#24
JOURNAL ARTICLE
Jonine Jancey, Renee N Carey, Becky Freeman, Tama Leaver, Katharina Wolf, Marilyn Bromberg, Kevin Chai, Stella Bialous, Phoebe Adams, Meghan Mcleod, Kahlia McCausland
INTRODUCTION: Mounting evidence suggests that electronic cigarettes (e-cigarettes) are extensively promoted and marketed using social media, including through user-generated content and social media influencers. This study explores how e-cigarettes are being promoted on Instagram, using a case-study approach, and the extent to which Meta's Restricted Goods and Services Policy (Meta's policy) is being applied and enforced. METHODS: We identified the accounts followed by an Australian Instagram influencer who primarily posts e-cigarette-related content...
2024: Tobacco Induced Diseases
#25
JOURNAL ARTICLE
Jennifer Simkin, Ajoy Aloysius, Mike Adam, Fatemeh Safaee, Renée R Donahue, Shishir Biswas, Zohaib Lakhani, John C Gensel, David Thybert, Steven Potter, Ashley W Seifert
The details of how macrophages control different healing trajectories (regeneration vs. scar formation) remain poorly defined. Spiny mice (Acomys spp.) can regenerate external ear pinnae tissue, whereas lab mice (Mus musculus) form scar tissue in response to an identical injury. Here, we used this dual species system to dissect macrophage phenotypes between healing modes. We identified secreted factors from activated Acomys macrophages that induce a pro-regenerative phenotype in fibroblasts from both species...
January 10, 2024: Developmental Cell
#26
JOURNAL ARTICLE
Maria Conticchio, Riccardo Inchingolo, Antonella Delvecchio, Francesca Ratti, Maximiliano Gelli, Massimiliano Ferdinando Anelli, Alexis Laurent, Giulio Cesare Vitali, Paolo Magistri, Giacomo Assirati, Emanuele Felli, Taiga Wakabayashi, Patrick Pessaux, Tullio Piardi, Fabrizio di Benedetto, Nicola de'Angelis, Javier Briceño, Antonio Rampoldi, Renè Adam, Daniel Cherqui, Luca Antonio Aldrighetti, Riccardo Memeo
BACKGROUND: Liver resection is the mainstay for a curative treatment for patients with resectable hepatocellular carcinoma (HCC), also in elderly population. Despite this, the evaluation of patient condition, liver function and extent of disease remains a demanding process with the aim to reduce postoperative morbidity and mortality. AIM: To identify new perioperative risk factors that could be associated with higher 90- and 180-d mortality in elderly patients eligible for liver resection for HCC considering traditional perioperative risk scores and to develop a risk score...
December 27, 2023: World Journal of Hepatology
#27
JOURNAL ARTICLE
Eric K van Staalduinen, Robert Matthews, Adam Khan, Isha Punn, Renee F Cattell, Haifang Li, Ana Franceschi, Ghassan J Samara, Lukasz Czerwonka, Lev Bangiyev, Tim Q Duong
Accurate differentiation of benign and malignant cervical lymph nodes is important for prognosis and treatment planning in patients with head and neck squamous cell carcinoma. We evaluated the diagnostic performance of magnetic resonance image (MRI) texture analysis and traditional 18F-deoxyglucose positron emission tomography (FDG-PET) features. This retrospective study included 21 patients with head and neck squamous cell carcinoma. We used texture analysis of MRI and FDG-PET features to evaluate 109 histologically confirmed cervical lymph nodes (41 metastatic, 68 benign)...
December 28, 2023: Diagnostics
#28
Jacqueline Renee Kulbe, Alexandra Anh Le, Michael Mante, Jazmin Florio, Anna Elizabeth Laird, Mary K Swinton, Robert A Rissman, Jerel Adam Fields
No abstract text is available yet for this article.
January 4, 2024: Journal of Neurovirology
#29
Leighanne R Main, Yeunjoo E Song, Audrey Lynn, Renee A Laux, Kristy L Miskimen, Michael D Osterman, Michael L Cuccaro, Paula K Ogrocki, Alan J Lerner, Jeffery M Vance, M Denise Fuzzell, Sarada L Fuzzell, Sherri D Hochstetler, Daniel A Dorfsman, Laura J Caywood, Michael B Prough, Larry D Adams, Jason E Clouse, Sharlene D Herington, William K Scott, Margaret A Pericak-Vance, Jonathan L Haines
INTRODUCTION: Alzheimer disease (AD) remains a debilitating condition with limited treatments and additional therapeutic targets needed. Identifying AD protective genetic loci may identify new targets and accelerate identification of therapeutic treatments. We examined a founder population to identify loci associated with cognitive preservation into advanced age. METHODS: Genome-wide association and linkage analyses were performed on 946 examined and sampled Amish individuals, aged 76-95, who were either cognitively unimpaired (CU) or impaired (CI)...
December 14, 2023: medRxiv
#30
JOURNAL ARTICLE
Jim Höppner, Sandra Krohn, Ellen H A van den Munckhof, René Kallies, Adam Herber, Katharina Zeller, Jan Tünnemann, Madlen Matz-Soja, Antonis Chatzinotas, Stephan Böhm, Albrecht Hoffmeister, Thomas Berg, Cornelius Engelmann
Small intestinal bacterial overgrowth and compositional changes of intestinal microbiota are pathomechanistic factors in liver cirrhosis leading to bacterial translocation and infectious complications. We analyzed the quantity and composition of duodenal bacterial DNA (bactDNA) in relation to bactDNA in blood and ascites of patients with liver cirrhosis. Duodenal fluid and corresponding blood and ascites samples from 103 patients with liver cirrhosis were collected. Non-liver disease patients (n = 22) served as controls...
December 27, 2023: Scientific Reports
#31
Antonius M H P van den Besselaar, Anne Stavelin, Steve Kitchen, Michelle Bryant, Armando Tripodi, Erica Scalambrino, Marigrazia Clerici, Petra Herbel, Anja Jünschke, Sascha Meyer Dos Santos, Piet Meijer, René W L M Niessen, Joost C M Meijers, Craig Thelwell, Adam Cuker, Chun Kung, Zhenghua Cao, Norbert Zander, Yosuke Iwasaki, François Depasse, Claudia van Rijn, Shanti Baktawar, Charmane Abdoel, Christa M Cobbaert
Calibration of Prothrombin Time (PT) in terms of the International Normalized Ratio (INR) has been outlined in 'Guidelines for thromboplastins and plasmas used to control oral anticoagulant therapy' (World Health Organization, 2013). International Standard ISO 17511:2020 presents requirements for manufacturers of In-vitro Diagnostic Medical Devices (IVD MD) in documenting the calibration hierarchy for a measured quantity in human samples using a specified IVD MD. The objective of this article is to define an unequivocal, metrologically traceable calibration hierarchy for the INR measured in plasma as well as in whole blood samples...
December 19, 2023: Journal of Thrombosis and Haemostasis: JTH
#32
JOURNAL ARTICLE
Tiefeng Liu, Johanna Heimonen, Qilun Zhang, Chi-Yuan Yang, Jun-Da Huang, Han-Yan Wu, Marc-Antoine Stoeckel, Tom P A van der Pol, Yuxuan Li, Sang Young Jeong, Adam Marks, Xin-Yi Wang, Yuttapoom Puttisong, Asaminew Y Shimolo, Xianjie Liu, Silan Zhang, Qifan Li, Matteo Massetti, Weimin M Chen, Han Young Woo, Jian Pei, Iain McCulloch, Feng Gao, Mats Fahlman, Renee Kroon, Simone Fabiano
Water-based conductive inks are vital for the sustainable manufacturing and widespread adoption of organic electronic devices. Traditional methods to produce waterborne conductive polymers involve modifying their backbone with hydrophilic side chains or using surfactants to form and stabilize aqueous nanoparticle dispersions. However, these chemical approaches are not always feasible and can lead to poor material/device performance. Here, we demonstrate that ground-state electron transfer (GSET) between donor and acceptor polymers allows the processing of water-insoluble polymers from water...
December 20, 2023: Nature Communications
#33
JOURNAL ARTICLE
Emily R Ko, Megan E Reller, L Gayani Tillekeratne, Champica K Bodinayake, Cameron Miller, Thomas W Burke, Ricardo Henao, Micah T McClain, Sunil Suchindran, Bradly Nicholson, Adam Blatt, Elizabeth Petzold, Ephraim L Tsalik, Ajith Nagahawatte, Vasantha Devasiri, Matthew P Rubach, Venance P Maro, Bingileki F Lwezaula, Wasantha Kodikara-Arachichi, Ruvini Kurukulasooriya, Aruna D De Silva, Danielle V Clark, Kevin L Schully, Deng Madut, J Stephen Dumler, Cecilia Kato, Renee Galloway, John A Crump, Geoffrey S Ginsburg, Timothy D Minogue, Christopher W Woods
Diagnostic limitations challenge management of clinically indistinguishable acute infectious illness globally. Gene expression classification models show great promise distinguishing causes of fever. We generated transcriptional data for a 294-participant (USA, Sri Lanka) discovery cohort with adjudicated viral or bacterial infections of diverse etiology or non-infectious disease mimics. We then derived and cross-validated gene expression classifiers including: 1) a single model to distinguish bacterial vs...
December 18, 2023: Scientific Reports
#34
JOURNAL ARTICLE
Amy N Stahl, Jordan M Racca, Cailey I Kerley, Adam Anderson, Bennett Landman, Linda J Hood, René H Gifford, Tonia S Rex
Auditory complaints are frequently reported by individuals with mild traumatic brain injury (mTBI) yet remain difficult to detect in the absence of clinically significant hearing loss. This highlights a growing need to identify sensitive indices of auditory-related mTBI pathophysiology beyond pure-tone thresholds for improved hearing healthcare diagnosis and treatment. Given the heterogeneity of mTBI etiology and the diverse peripheral and central processes required for normal auditory function, the present study sought to determine the audiologic assessments sensitive to mTBI pathophysiology at the group level using a well-rounded test battery of both peripheral and central auditory system function...
December 5, 2023: Hearing Research
#35
JOURNAL ARTICLE
Mariano Cesare Giglio, Pasquale Dolce, Sezai Yilmaz, Yaman Tokat, Koray Acarli, Murat Kilic, Murat Zeytunlu, Tarkan Unek, Vincent Karam, René Adam, Wojciech Grzegorz Polak, Constantino Fondevila, Silvio Nadalin, Roberto Ivan Troisi
Graft survival is a critical endpoint in adult-to-adult living donor liver transplantation (ALDLT), where graft procurement endangers the lives of healthy individuals. Therefore, ALDLT must be responsibly performed in the perspective of a positive harm-to-benefit ratio. This study aimed to develop a risk prediction model for early (3-months) graft failure (EGF) following ALDLT. Donor and recipient factors associated with EGF in ALDLT were studied using data from the European Liver Transplant Registry. An artificial neural network classification algorithm (ANN) was trained on a set of 2073 ALDLTs, validated using cross-validation, tested on an independent random-split sample (n=518), and externally validated on United Network for Organ Sharing Standard Transplant Analysis and Research data...
December 12, 2023: Liver Transplantation
#36
JOURNAL ARTICLE
Sophie-Caroline- Sacleux, Philippe Ichaï, Audrey Coilly, Marc Boudon, Elise Lemaitre, Rodolphe Sobesky, Eleonora De Martin, Valérie Cailliez, Ilias Kounis, Edoardo Poli, Marie-Amélie Ordan, Alina Pascale, Jean-Charles Duclos-Vallée, Cyrille Feray, Daniel Azoulay, Eric Vibert, Daniel Cherqui, René Adam, Didier Samuel, Faouzi Saliba
BACKGROUND & AIMS: Retrospective studies have reported good results with liver transplantation (LTx) for acute-on-chronic liver failure (ACLF) in selected patients. The aim of this study was to evaluate the selection process for LTx in patients with ACLF admitted to the intensive care unit (ICU) and to assess outcomes. METHODS: This prospective, non-interventional, single high-volume center study collected data on patients with ACLF admitted to the ICU between 2017-2020...
January 2024: JHEP reports: innovation in hepatology
#37
JOURNAL ARTICLE
Somalee Banerjee, Amy Alabaster, Alyce S Adams, Renee Fogelberg, Nihar Patel, Kelly Young-Wolff
OBJECTIVE: To assess the effects of an electronic health record (EHR) intervention that prompts the clinician to prescribe nicotine replacement therapy (NRT) at hospital admission and discharge in a large integrated health system. DESIGN: Retrospective cohort study using interrupted time series (ITS) analysis leveraging EHR data generated before and after implementation of the 2015 EHR-based intervention. SETTING: Kaiser Permanente Northern California, a large integrated health system with 4...
December 6, 2023: BMJ Open
#38
JOURNAL ARTICLE
David Badrudin, Mickaël Lesurtel, Shailesh Shrikhande, Tom Gallagher, Stefan Heinrich, Susanne Warner, Vikram Chaudhari, Donna Koo, Sandeep Anantha, Víctor Molina, Mikel Prieto Calvo, Marc-Antoine Allard, Alexandre Doussot, Amar Kourdouli, Mikhail Efanov, Ricardo Oddi, Pablo Barros-Schelotto, Mert Erkan, Michael Lidsky, Federico Garcia, Maximiliano Gelli, Ayrat Kaldarov, Pablo Granero, Nicolas Meurisse, René Adam
BACKGROUND: In response to the pandemic, the International Hepato-Pancreato-Biliary Association (IHPBA) developed the IHPBA-COVID Registry to capture data on HPB surgery outcomes in COVID-positive patients prior to mass vaccination programs. The aim was to provide a tool to help members gain a better understanding of the impact of COVID-19 on patient outcomes following HPB surgery worldwide. METHODS: An online registry updated in real time was disseminated to all IHPBA, E-AHPBA, A-HPBA and A-PHPBA members to assess the effects of the pandemic on the outcomes of HPB procedures, perioperative COVID-19 management and other aspects of surgical care...
September 1, 2023: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#39
REVIEW
Dana Wong, Kerryn Pike, Rene Stolwyk, Kelly Allott, Jennie Ponsford, Adam McKay, Wendy Longley, Pascalle Bosboom, Antoinette Hodge, Glynda Kinsella, Loren Mowszowski
Delivery of neuropsychological interventions addressing the cognitive, psychological, and behavioural consequences of brain conditions is increasingly recognised as an important, if not essential, skill set for clinical neuropsychologists. It has the potential to add substantial value and impact to our role across clinical settings. However, there are numerous approaches to neuropsychological intervention, requiring different sets of skills, and with varying levels of supporting evidence across different diagnostic groups...
November 30, 2023: Neuropsychology Review
#40
JOURNAL ARTICLE
Jacqueline Renee Kulbe, Lauren Nguyen, Alexandra Anh Le, Anna Elizabeth Laird, Michael A Taffe, Jacques D Nguyen, Jerel Adam Fields
E-cigarette use has been marketed as a safer alternative to traditional cigarettes, as a means of smoking cessation, and are used at a higher rate than the general population in people with HIV (PWH). Early growth receptor 2 (EGR2) and Activity-Regulated Cytoskeleton-Associated Protein (ARC) have a role in addiction, synaptic plasticity, inflammation, and neurodegeneration. This study showed that 10 days of exposure to e-cigarette vapor altered gene expression in the brains of 6-month-old, male, Sprague Dawley rats...
November 7, 2023: Brain Sciences
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
