Emma Frasson, Maria Chiara Tozzi, Monia Bordignon, Luisa Motti, Francesca Ferrari, Gabriella Torre, Alessandra Graziottin, Salvatore Monaco, Laura Bertolasi
PURPOSE: Laser-evoked potentials (LEPs) are useful neurophysiological tools for investigating the A-delta sensory peripheral fibers and the central nociceptive pathway. The current investigation aims to obtain normative values of LEPs via pudendal nerve stimulation in healthy adult volunteers. METHODS: Laser-evoked potentials were recorded in 16 men and 22 women, 22 to 75 years of age, using neodymium and yttrium and aluminum and perovskite laser bilateral stimulation to the pudendal nerve-supplied skin and the dorsal surface of the hands and feet...
March 20, 2020: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
Ahmed M Sanad, Soha E Younis, Mohamed A Oraby, Hesham Hegazy, Ahmed I El-Sakka
BACKGROUND: The angiographically documented association between severity of coronary artery disease (CAD) and aorto-ilio-pudendal (A-I-P) artery disease and vascular erectile dysfunction (ED) was not yet settled. AIM: To assess the relation between angiographically proved CAD and A-I-P artery disease in patients with ischemic heart disease (IHD)-associated vascular ED. METHODS: 60 men were assigned to 3 study groups: Group 1 (n = 25), patients who had IHD and ED; group 2 (n = 25), patients who had IHD and had no ED; group 3 (n = 10), patients who had ED and had no suspected IHD...
March 16, 2020: Journal of Sexual Medicine
Jie Cai, Diming Wang, Feng-Qi Zhao, Shulin Liang, Jianxin Liu
Background: The local supply of energy-yielding nutrients such as glucose seems to affect the synthesis of milk components in the mammary gland (MG). Thus, our study was conducted to investigate the effects of locally available MG glucose supply (LMGS) on amino acid (AA) sensing and utilization in the MG of lactating dairy goats. Six dosages of glucose (0, 20, 40, 60, 80, and 100 g/d) were infused into the MG through the external pudendal artery to investigate the dose-dependent changes in mammary AA uptake and utilization (Exp...
2020: Journal of Animal Science and Biotechnology
Micah Levy, Christine M Bassis, Eric Kennedy, Katie E Yoest, Jill B Becker, Jason Bell, Mitchell B Berger, Tim M Bruns
Treatment options are limited for the approximately 40% of postmenopausal women worldwide who suffer from female sexual dysfunction (FSD). Neural stimulation has shown potential as a treatment for genital arousal FSD, however the mechanisms for its improvement are unknown. One potential cause of some cases of genital arousal FSD are changes to the composition of the vaginal microbiota, which is associated with vulvovaginal atrophy. The primary hypothesis of this study was that neural stimulation may induce healthy changes in the vaginal microbiome, thereby improving genital arousal FSD symptoms...
2020: PloS One
Andreas Gohritz, Arnold Lee Dellon
Background  Interstitial cystitis (IC) or bladder pain syndrome (BPS) is highly painful and disabling and probably the most misdiagnosed urologic condition. Its classic symptoms of perineal pain, urinary urgency, and frequency despite sterile urine cultures were already described more than a century ago in a report on soldiers during World War (WW) I due to chronic pudendal nerve compression. Objectives  This article translates a report from 1915 on pudendal neuropathy and discusses its author Georg Zülzer (1870-1949)...
January 2020: Journal of Brachial Plexus and Peripheral Nerve Injury
Samuel A J Fidder, Georg J Furtmüller, Andres Matoso, Joanna W Etra, Kara Lombardo, Maria Chicco, Byoung Chol Oh, Dalibor Vasilic, Wp Andrew Lee, Richard J Redett, Damon S Cooney, Gerald Brandacher
Penis transplantation represents an exciting new avenue for restoration of male genitalia and function after devastating tissue loss. This animal model is designed to fill a critical void to study immunologic aspects related to reconstructive transplantation of male genitalia. A rat penile graft dissection was designed based on the internal pudendal arteries and dorsal penile vein and includes the skin of the prepuce. A non-suture cuff technique was used to anastomose the graft vessels to the recipient superficial epigastric and femoral vessels...
March 7, 2020: Transplant International
Katherine Shapiro, Natalie Pace, Tara Morgan, Haotian Cai, Bing Shen, Jicheng Wang, James R Roppolo, William C de Groat, Changfeng Tai
Objective: To determine the inhibitory effect on bladder activity induced by bilateral pudendal neuromodulation. Methods: In 10 cats under anesthesia, two tripolar cuff electrodes were implanted bilaterally on the pudendal nerves for stimulation. A double lumen catheter was inserted into the bladder through the urethra to infuse saline and measure bladder pressure. During repeated cystometrograms (CMGs) pudendal nerve stimulation (PNS: 5 Hz, 0.2 ms, 5-15 min) was applied unilaterally or bilaterally at 1- or 2-times intensity threshold ( T ) for inducing anal sphincter twitching...
2020: Frontiers in Neuroscience
J Mercier, M Morin, A Tang, B Reichetzer, M-C Lemieux, K Samir, D Zaki, F Gougeon, C Dumoulin
Objective: This study aims to investigate the mechanism of action of pelvic floor muscle training (PFMT) for the improvement of the signs and symptoms of genitourinary syndrome of menopause (GSM) in postmenopausal women with GSM and urinary incontinence (UI). Methods: Twenty-nine women were included in the secondary analysis of a single-arm feasibility study. Using color Doppler ultrasound, the peak systolic velocity, time-averaged maximum velocity, and pulsatility index of the internal pudendal and dorsal clitoral arteries were measured at rest and after a pelvic floor muscle (PFM) contraction task...
February 27, 2020: Climacteric: the Journal of the International Menopause Society
Takahiko Mine, Tatsuo Ueda, Daisuke Yasui, Shohei Mizushima, Shin-Ichiro Kumita
PURPOSE: We aimed to illustrate the benefits of using warmed glue for viscosity reduction via the triaxial microballoon system for the treatment of various vascular disorders. METHODS: Seven patients who underwent 10 treatment sessions for hemoptysis, type II endoleak, post-pancreatic surgical bleeding, spontaneous retroperitoneal bleeding, or ovarian tumor bleeding were evaluated based on technical and clinical outcomes. In the procedure, the triaxial system, consisting of a 4...
February 19, 2020: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
Geertje Callewaert, Marina Gabriela Monteiro Carvalho Mori Da Cunha, Karel Dewulf, Maarten Albersen, Jan Deprest
BACKGROUND: Although pelvic floor dysfunction (PFD) has a multifactorial etiology, pregnancy and childbirth are considered crucial events predisposing to urinary incontinence as well as pelvic organ prolapse, which are highly prevalent. Rats are the most frequently used animal model and pudendal nerve crush (PNC) and vaginal distension (VD) are often used to mimic vaginal delivery. OBJECTIVE: To document the time course of events after simulated vaginal delivery (SVD) on the urethral sphincter and the vaginal smooth muscle layer...
February 12, 2020: Neurourology and Urodynamics
Ugo Indraccolo, Roberto Nardulli, Salvatore R Indraccolo
BACKGROUND: There is a gap between pudendal neuralgia (PN) due to pudendal entrapment syndrome and PN without pudendal entrapment syndrome. The latter could have atypical symptoms. AIM: Defining a rate of atypical PN from a clinical series of female patients with chronic pelvic-perineal pain. METHODS: The atypical PN was defined as a pain not meeting clinical criteria for pudendal entrapment syndrome. The effect size was the rate of atypical PN...
February 5, 2020: Neurourology and Urodynamics
Hyun Gun Lee, Soo Yeon Lim, Chi Sun Yoon, Kyu Nam Kim
RATIONALE: The challenges with reconstruction of penile defects are plenty. In addition, no single and universally accepted reconstructive method exists for penile defect repair. Herein, we present the application of a circumferential penile shaft defect reconstruction using pull-up double-opposing keystone-designed perforator island flaps (KDPIFs) in one patient. This is the first case report of a circumferential penile shaft defect reconstruction using KDPIFs. PATIENT CONCERNS: A 43-year-old man who injected petroleum jelly into his penis 10 years ago presented with multiple firm nodular mass-like lesions adherent to the overlying skin along the penile shaft...
January 2020: Medicine (Baltimore)
Xin Gu, Parth U Thakker, Ethan L Matz, Ryan P Terlecki, Frank C Marini, Julie G Allickson, Tom F Lue, Guiting Lin, Anthony Atala, James J Yoo, Yuanyuan Zhang, John D Jackson
INTRODUCTION: The human placenta provides a bountiful and noncontroversial source of stem cells which have the potential for regeneration of injured tissue. These cells may restore erectile function after neurovascular tissue injury such as that seen in radical pelvic surgeries and pelvic trauma. AIM: To determine the effect of human placenta-derived stem cells on erectile function recovery and histological changes at various time points in a cavernous nerve injury rat model and to study the fate of injected stem cells throughout the regenerative process...
January 27, 2020: Journal of Sexual Medicine
Luigi Brusciano, Salvatore Tolone, Gianmattia Del Genio, Ugo Grossi, Antonio Schiattarella, Francesco Pio Piccolo, Jacopo Martellucci, Michele Schiano di Visconte, Ludovico Docimo
BACKGROUND: Intersphincteric injectable bulking agents are one of the current treatment options for fecal incontinence failing behavioral and medical therapy. Gatekeeper showed promising short-term results but long-term outcomes are unknown. OBJECTIVE: To clinically evaluate a prospective cohort of fecal incontinence patients up to 36 months after implantation of Gatekeeper. DESIGN: Prospective clinical study. SETTINGS: The study was conducted at a large university tertiary care hospital...
January 30, 2020: Diseases of the Colon and Rectum
Jong Yun Choi, Jin Tae Cho, Bommie Florence Seo, Jangyoun Choi, Sung-No Jung
No abstract text is available yet for this article.
January 2020: Archives of Plastic Surgery
Kachina Allen, Nan Wise, Eleni Frangos, Barry Komisaruk
INTRODUCTION: The projection of the human male urogenital system onto the paracentral lobule has not previously been mapped comprehensively. AIM: To map specific urogenital structures onto the primary somatosensory cortex toward a better understanding of sexual response in men. METHODS: Using functional magnetic resonance imaging, we mapped primary somatosensory cortical responses to self-stimulation of the penis shaft, glans, testicles, scrotum, rectum, urethra, prostate, perineum, and nipple...
January 14, 2020: Journal of Sexual Medicine
B Kahle
BACKGROUND: Foam sclerotherapy is well established in the treatment of varicose veins of different sizes. METHODS: A literature review was performed to determine whether specific anatomical findings could be a limitation for foam sclerotherapy. RESULTS: The following anatomical aspects are relevant as a potential limitation for foam sclerotherapy: treatment of pudendal veins, varicose veins in patients with chronic lymphedema and lymph fistulas...
January 2020: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
Michelle L Tucker, David G Wilson, Spencer M Barber
OBJECTIVE: To document marked hemorrhage as a complication of inguinal cryptorchidectomy and its successful treatment with a novel chitosan-based hemostatic agent. STUDY DESIGN: Case report. ANIMALS: One healthy 5-year old quarter horse cryptorchid. METHODS: The horse was presented for routine unilateral cryptorchidectomy after prior hemicastration. An inguinal approach was made to the abdomen, and the right external pudendal artery was lacerated at the level of the internal inguinal ring, requiring multiple anesthetic events over a 2-week period in attempts to control hemorrhage...
January 9, 2020: Veterinary Surgery
Ahmet Kale, Taner Usta, Gulfem Basol, Isa Cam, Melike Yavuz, Hande G Aytuluk
PURPOSE: Pudendal neuralgia (PN) is a painful and disabling condition, which reduces the quality of life as well. Pudendal nerve infiltrations are essential for the diagnosis and the management of PN. The purpose of this study was to compare the effectiveness of finger-guided transvaginal pudendal nerve infiltration (TV-PNI) technique and the ultrasound-guided transgluteal pudendal nerve infiltration (TG-PNI) technique. METHODS: Forty patients who underwent PNI for the diagnosis of PN were evaluated...
December 2019: International Neurourology Journal
Kevin M Klifto, A Lee Dellon
BACKGROUND: Loss of penile sensation or development of a painful penis and erectile dysfunction can occur after injury to the dorsal branch of the pudendal nerve. Although recovery of genital sensibility has been discussed frequently in transmen, this subject has been reported rarely in cismen. The purpose of this report is to review our experience with recovery of sensation in men after decompression of the dorsal branch of the pudendal nerve after trauma. METHODS: A retrospective chart review of men who have had decompression of the dorsal branch of the pudendal nerve was carried out from 2014 to 2018...
January 3, 2020: Annals of Plastic Surgery
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