Marco Baron Toaldo, Chiara Mazzoldi, Giovanni Romito, Helen Poser, Barbara Contiero, Mario Cipone, Carlo Guglielmini
BACKGROUND: Atrial fibrillation (AF) occurs in dogs with myxomatous mitral valve disease (MMVD) as a consequence of left atrial (LA) dilatation, and it affects survival and quality of life. OBJECTIVES: To evaluate the usefulness of echocardiography in predicting the first occurrence of AF in dogs with MMVD. ANIMALS: Forty-four client-owned dogs with MMVD, 22 dogs that developed AF, and 22 dogs that maintained sinus rhythm. METHODS: Retrospective observational study...
August 7, 2020: Journal of Veterinary Internal Medicine
Jie Zhang, Xijiang Zhang
Ischaemia/reperfusion (I/R) injury can lead to severe arrhythmia and aggravate myocardial damage. Exosomes are small-membrane vesicles that play a protective role in myocardial I/R injury. This study aimed to explore the protective effects of ischaemic preconditioning (IPC)-induced serum exosomes (IPC-Exo) on myocardial I/R injury in rats and its underlying mechanism. Serum exosomes were extracted from IPC rats and quantified using a bicinchoninic acid assay kit. IPC-Exo (50 μg) was injected into the infarcted myocardium immediately after ligation...
August 7, 2020: Cell Biochemistry and Function
Xiaohao Zhang, Wenbo Zhao, Xinxin Ma, Yuanqing Li, Hongli Shang, Jun Zhang, Zengchun Ye, Xun Liu, Tanqi Lou, Yu Peng, Hui Peng
BACKGROUND: Pulmonary hypertension is common in chronic kidney disease (CKD) patients. However, the prognostic value of pulmonary hypertension in Chinese predialytic CKD patients is rarely reported. We evaluated the relevant factors and prognostic value of pulmonary hypertension in CKD patients. METHODS: This retrospective cohort study enrolled 1092 predialytic patients from The Third Affiliated Hospital of Sun Yat-Sen University from May 1st, 2011, to December 31st, 2016...
August 7, 2020: International Urology and Nephrology
Yumei Ye, Yochai Birnbaum, Steven G Widen, Zhaohui Zhang, Shipeng Zhu, Mandeep Bajaj, Huan Chen
PURPOSE: To assess the effects of electro-acupuncture (EA) on glycemic control, myocardial inflammation, and the progression of diabetic cardiomyopathy in mice with type 2 diabetes. METHODS: Db/Db mice received EA at PC6+ST36 (DM-Acu), non-acupoint simulation (DM-Sham), or no treatment (DM). EA was applied for 30 min per day, 5 days a week for 4 weeks. Heart function was assessed by echocardiography. Myocardium was assessed by RT-PCR, immunoblotting, and histology...
August 7, 2020: Cardiovascular Drugs and Therapy
Zhaohuan Li, Jing Tan, Xuebing Liu, Wenjun Zhang, Qingguo Meng, Mi Zhou, Ni Lin, Fei Cao, Jing Lu, Jun Liu, Lixue Yin
Use of echocardiography to evaluate the characteristics of right heart and pulmonary artery of Tibetans with hepatic hydatidosis living in a high plateau area. We recruited 222 Tibetan adults diagnosed with hydatidosis from June 2016 to June 2017 in Shiqu and Seda areas of Tibet; 40 healthy control from the same area, denoted as the high plateau group. We also include 755 Healthy adults of Han nationality living in the plain from the EMINCA study as the low altitude group. Compared to high plateau group, hydatidosis individuals showed decreased RVADed, RVTDed, increased E(T)/A(T) and reduced RVFAC and TAPSE (p < 0...
August 6, 2020: International Journal of Cardiovascular Imaging
Paraskevi Theocharis, James Wong, Kuberan Pushparajah, Sujeev K Mathur, John M Simpson, Emma Pascall, Aoife Cleary, Kirsty Stewart, Kaitav Adhvaryu, Alex Savis, Saleha R Kabir, Mirasol Pernia Uy, Hannah Heard, Kelly Peacock, Owen Miller
AIMS: Following the peak of the UK COVID-19 epidemic, a new multisystem inflammatory condition with significant cardiovascular effects emerged in young people. We utilized multimodality imaging to provide a detailed sequential description of the cardiac involvement. METHODS AND RESULTS: Twenty consecutive patients (mean age 10.6 ± 3.8 years) presenting to our institution underwent serial echocardiographic evaluation on admission (median day 5 of illness), the day coinciding with worst cardiac function (median day 7), and the day of discharge (median day 15)...
August 7, 2020: European Heart Journal Cardiovascular Imaging
Erik L Frandsen, Soultana Kourtidou, Joel S Tieder, Erin Alberda, Brian D Soriano
Introduction: Appropriate use criteria (AUC) guide initial transthoracic echocardiogram (TTE) use in outpatient pediatrics. We sought to improve pediatric cardiologist TTE ordering appropriateness (mean AUC score) with a quality improvement initiative. Methods: The outcome of interest was the prospective AUC score for all initial outpatient TTEs ordered between November 2016 and August 2017, categorized per the AUC: "appropriate" (score 7-9), "may be appropriate" (4-6), "rarely appropriate" (1-3)...
July 2020: Pediatric Quality & Safety
Giuseppe Damiano Sanna, Eleonora Moccia, Mauro Pepi, Guido Parodi
Transcatheter aortic valve replacement (TAVR) is an alternative treatment option for patients with severe aortic stenosis. Although rarely described, mitral valve perforation because of mechanical stimulation due to low deployment of the prosthesis and the association with infective endocarditis, are potentially life-threatening complications that physicians should be aware of because patients should not be suitable for further surgical or percutaneous management. Herein, we present a case of an 88-year-old man presenting with worsening heart failure 6 months after TAVR...
January 2020: Journal of Cardiovascular Echography
Andrea Sonaglioni, Antonio Vincenti, Michele Lombardo, Claudio Anzà
An 88-year-old male with nonvalvular atrial fibrillation (NVAF) and severe congestive heart failure (HF), was admitted to the Neurological Intensive Care Unit because of the acute onset of aphasia and left hemiplegia. Transthoracic echocardiography revealed a left atrial (LA) cavity thrombus. Its "fatal" distal embolization to abdominal aorta occurred in a few days. These observations should lead to a cautious approach in proposing a percutaneous closure of LA appendage in older NVAF patients, with HF and/or left ventricular dysfunction and larger LA volumes, who are not adequately anticoagulated...
January 2020: Journal of Cardiovascular Echography
Georgios Christopoulos, Zachary Barrett-O'Keefe, Krishnaswamy Chandrasekaran
The clinical distinction between athlete's heart and structural heart disease in the echocardiography laboratory is often challenging. We present a case where athletic heart syndrome was promptly differentiated from pathology with a simple maneuver during echocardiography.
January 2020: Journal of Cardiovascular Echography
Simone Frea, Alessandro Andreis, Vittoria Scarlatta, Chiara Rovera, Alessandro Vairo, Erika Pistone, Matteo Anselmino, Pier Giorgio Golzio, Mauro Toppino, Carla Giustetto, Fiorenzo Gaita
Aim: Obesity is associated with an increased cardiovascular risk. This study aimed to assess the role of echocardiography in the early detection of subclinical cardiac abnormalities in a cohort of obese patients with a preserved ejection fraction (EF) undergoing bariatric surgery. Methods and Results: Forty consecutive severely obese patients (body mass index≥35 kg/m2) referring to our center for bariatric surgery were enrolled in this prospective cohort study...
January 2020: Journal of Cardiovascular Echography
Shun Ijuin, Ali Hamadanchi, Franz Haertel, Laura Baez, Paul Christian Schulze, Marcus Franz, Sven Moebius-Winkler
Background: Various clinical trials provide evidence about the safety, effectiveness, and therapeutic success of percutaneous left atrial appendage closure (LAAC) using various occlusion devices. These devices are foreign materials implanted into the left atrium and may deteriorate left atrial (LA) function. The aim of this study was to evaluate the change in transesophageal echocardiography (TEE)-derived LA strain after LAAC. Methods and Results: The study included 95 patients (age: 75 ± 6...
January 2020: Journal of Cardiovascular Echography
Paolo Diego L'Angiocola, Roberto Donati
Transthoracic echocardiography is a useful diagnostic technique for the identification of intracardiac and extracardiac masses, which can evaluate morphologic properties of the masses such as their location, attachment, shape, size, mobility, and possible hemodynamic-related implications. Apart from physiological variants and structural normal mimickers, echocardiography can detect principal intracardiac masses such as neoplasms, thrombi, vegetation, and extracardiac masses such as metastatic lesions. Moreover, transesophageal echocardiography can provide further details and provide higher accuracy in case a deeper examination of the mass is needed...
January 2020: Journal of Cardiovascular Echography
Francesco Antonini-Canterin, Mauro Pepi, Ines Paola Monte, Giuseppe Trocino, Andrea Barbieri, Agata Barchitta, Quirino Ciampi, Alberto Cresti, Sofia Miceli, Licia Petrella, Frank Benedetto
The epidemic of COVID-19 has grown to pandemic proportions and the preventive and mitigation measures have been widely spread through the media. The cardiologists are called as consultants for the cardiovascular pathologies and echocardiography is a fundamental examination in many clinical situations, but not without risks for health staff. Società Italiana di Ecocardiografia e CardioVascular Imaging Council has decided to formulate a document aimed to highlight the importance of a correct indication and execution procedure of the echocardiogram during a COVID-19 pandemic...
January 2020: Journal of Cardiovascular Echography
Farah Anum Jameel, Abdul Mannan Junejo, Qurat Ul Ain Khan, Sudeep Date, Ahmad Faraz, Syed Hasan Mustafa Rizvi, Fatima Ahmad, Muhammad Tahir
Introduction Chronic kidney disease (CKD) carries a significant association with cardiac diseases, which suggests a minor reduction in the glomerular filtration rate (GFR) can act as an independent risk factor for causing cardiovascular abnormalities. Patients of CKD having cardiovascular disease (CVD) had three to thirty times higher risk of mortality as compared to the general population. In addition, mortality among cardiovascular patients has been found to be twofold higher in CKD stage 2 patients and three-fold higher in patients with stage 3 CKD, when collated to patients with normal renal function...
July 2, 2020: Curēus
Worapong Nasomsong, Vasin Vasikasin, Jantima Traipattanakul, Dhitiwat Changpradub
Background: Streptococcus gallolyticus , formerly known as one of the Streptococcus bovis group, is frequently associated with endocarditis. Current guidelines recommended diagnostic work-up for endocarditis among patients with S. gallolyticus bacteremia. However, S. gallolyticus subsp. pasteurianus , was found to be associated with neonatal sepsis and liver diseases and is less commonly associated with endocarditis compared with S. gallolyticus subsp. gallolyticus . Our study aimed to identify the risk factors for S...
2020: Infection and Drug Resistance
Panagiota Pietri, George Georgiopoulos, Dimitrios Tsiachris, Athanasios Kordalis, Charalambos Vlachopoulos, Gregory Vyssoulis, Christodoulos Stefanadis
Given the inconsistent results on the prognostic significance of triglycerides (TGs), the purpose of the present study was to investigate the association of plasma TGs with left ventricular mass (LVM) in hypertensive patients. We studied 760 never treated, non diabetic, hypertensive patients. Τransthoracic echocardiography was performed and LVMI was calculated according to the Devereux formula, adjusted to body surface area. Triglycerides were associated with LVMI after adjustment for age, gender, systolic blood pressure (SBP), smoking and fasting glucose (b = 0...
August 6, 2020: Scientific Reports
Ilkka Heinonen, Oana Sorop, Bas M van Dalen, Rob C I Wüst, Jens van de Wouw, Vincent J de Beer, Yanti Octavia, Richard W B van Duin, Youri Hoogstrate, Lau Blonden, Milla Alkio, Katja Anttila, Andrew Stubbs, Jolanda van der Velden, Daphne Merkus, Dirk J Duncker
The prevalence of diabetic metabolic derangement (DMetD) has increased dramatically over the last decades. Although there is increasing evidence that DMetD is associated with cardiac dysfunction, the early DMetD-induced myocardial alterations remain incompletely understood. Here, we studied early DMetD-related cardiac changes in a clinically relevant large animal model. DMetD was established in adult male Göttingen miniswine by streptozotocin injections and a high-fat, high-sugar diet, while control animals remained on normal pig chow...
August 6, 2020: Scientific Reports
Mirae Lee, Ju Hyeon Oh
BACKGROUND: The diagnosis and quantification of right-to-left shunt (RLS) using transthoracic echocardiography (TTE) as well as transoesophageal echocardiography (TOE) have not been well established. We aimed to diagnose RLS by TOE using direct visualisation of the shunt and to compare the diagnosis with TTE diagnosis using conventional methods. METHODS AND RESULTS: We evaluated 141 patients with ischaemic stroke for RLS by both non-sedation TOE and TTE using saline contrast and Valsalva manoeuvre...
August 2020: Open Heart
Sukanya Phungphong, Anusak Kijtawornrat, Jonggonnee Wattanapermpool, Tepmanas Bupha-Intr
A rise in heart disease incidence in women after menopause has led to investigations into the role of female sex hormones on cardiac function. Although various adverse changes in cardiac contractile function following loss of female sex hormones have been reported, a clear mechanism of action has never been characterized. In order to examine whether an elevation in oxidative stress is a major cause of cardiac contractile dysfunction after female sex hormone deprivation, cardiac functions of ovariectomized rats with and without supplementation of superoxide scavenger tempol were compared to those of sham-operated controls...
August 4, 2020: Free Radical Biology & Medicine
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