keyword
https://read.qxmd.com/read/38699221/out-of-hospital-cardiac-arrest-in-the-eye-of-the-beholder-and-emergency-medical-service
#1
JOURNAL ARTICLE
Lorka Tarnovski, Porin Šantek, Ivana Rožić, Đivo Čučević, Luka Matej Mahečić, Jana Marić, Josip Lovaković, Dejana Martinić, Fran Rašić, Žarko Rašić
PURPOSE: Out-of-hospital cardiac arrest (OHCA) remains a global healthcare problem, with low survival and bystander cardiopulmonary resuscitation (CPR) rates. This study aimed to identify event-related factors in OHCA and their impact on return of spontaneous circulation (ROSC) achievement and maintenance until hospital admission. PATIENTS AND METHODS: All data were collected from Utstein Resuscitation Registry Template for OHCA from The Institute of Emergency Medicine of Zagreb from January 2012 to August 2022...
2024: Open Access Emergency Medicine: OAEM
https://read.qxmd.com/read/38698511/stop-the-bleed%C3%A2-in-medical-schools-early-advocacy-and-promising-results
#2
MULTICENTER STUDY
Jeremy Fridling, Brad Chernock, Tessa Goebel, Alyssa Tutunjian, Adam D Fox, Jane Keating, Lenworth Jacobs
OBJECTIVE: We hypothesized that medical students would be empowered by hemorrhage-control training and would support efforts to include Stop the Bleed® (STB) in medical education. DESIGN: This is a multi-institution survey study. Surveys were administered immediately following and 6 months after the course. SETTING: This study took place at the Association of American Medical Colleges-accredited medical schools in the United States. PARTICIPANTS: Participants were first-year medical students at participating institutions...
April 2024: American Journal of Disaster Medicine
https://read.qxmd.com/read/38696440/egg-consumption-and-bone-mass-density-among-the-elderly-a-scoping-review
#3
JOURNAL ARTICLE
Mobolaji T Olagunju, Olunike R Abodunrin, Ifeoluwa O Omotoso, Ifeoluwa E Adewole, Oluwabukola M Ola, Chukwuemeka Abel, Folahanmi T Akinsolu
Eggs offer a range of essential nutrients that could support skeletal health as individuals age. Maintaining bone density is crucial for reducing the risk of fractures and improving overall mobility and quality of life in later years. Understanding the potential benefits of habitual egg consumption on bone mass density among older people is essential, given that the natural decline in bone mass density occurs with age. This area of research has not garnered sufficient attention basically because of the mixed reactions and conflicting reports about the safety of egg consumption especially among the older adults...
2024: PLOS Glob Public Health
https://read.qxmd.com/read/38694980/the-ghana-heart-initiative-a-health-system-strengthening-approach-as-index-intervention-model-to-solving-ghana-s-cardiovascular-disease-burden
#4
JOURNAL ARTICLE
Alfred K Doku, John Tetteh, Juliette Edzeame, Ron J G Peters, Charles Agyemang, Elom Hillary Otchi, Alfred Edwin Yawson
Cardiovascular diseases (CVD) are the leading cause of death worldwide, with 80% of these deaths occurring in low-middle income countries (LMICs). In Ghana and across Africa, CVDs have emerged as the leading causes of death primarily due to undetected and under treated hypertension, yet less than 5% of resources allocated to health in these resource-poor countries go into non-communicable diseases (NCD) including CVD prevention and management. Consequently, most countries in Africa do not have contextually appropriate and sustainable health system framework to prevent, detect and manage CVD to achieve Universal Health Coverage (UHC) in CVD care through improved Primary Health Care (PHC) with the aim of achieving Sustainable Development Goals (SDG) in CVD/NCD...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38694841/is-a-portable-pressure-plate-an-alternative-to-force-plates-for-measuring-postural-stability-and-interlimb-coordination-of-quiet-standing-balance-control
#5
JOURNAL ARTICLE
Jonas Schröder, Ann Hallemans, Wim Saeys, Laetitia Yperzeele, Gert Kwakkel, Steven Truijen
INTRODUCTION: Center-of-pressure (COP) synchronization and symmetry can inform adaptations in balance control following one-sided sensorimotor impairments (e.g., stroke). As established force plates are impossible to transport, we aimed to criterion validate a portable pressure plate for obtaining reliable COP synchronization and symmetry measures, next to conventional postural stability measures. METHODS: Twenty healthy adults participated. In a single session, three 40-s eyes-open and eyes-closed quiet stance trials were performed per plate-type, randomly ordered...
2024: Journal of Rehabilitation and Assistive Technologies Engineering
https://read.qxmd.com/read/38690472/barriers-impact-the-primary-healthcare-providers-when-dealing-with-emergency-cases-a-cross-sectional-study-in-al-ahsa-saudi-arabia
#6
JOURNAL ARTICLE
Ghufran AlAbdullah, Fatemah Al Ahmed, Zahra J Alatiyyah, Ghadeer Alibraheem, Abdullah Almuqahwi
Introduction Being the first in-line care providers, primary healthcare (PHC) physicians may encounter all forms of medical emergencies, ranging from minor complaints to major life-threatening events; therefore, this study aims to assess the PHC physicians' knowledge and attitude related to the diagnosis and management of emergency cases as well as their preferences for emergency medicine training courses and their preferred methods of training. Methods A descriptive cross-sectional study was conducted among physicians working at PHC in Al-Ahsa, Saudi Arabia, between November and December 2023, excluding those who do not work at PHC...
March 2024: Curēus
https://read.qxmd.com/read/38690236/effectiveness-of-basic-life-support-training-course-intervention-among-dental-practitioners-and-students-an-experimental-study
#7
JOURNAL ARTICLE
Shivananda Shivakumar, Vidya Gowdappa Doddawad, Sahith Kumar Shetty, Manjula Shivanagappa, Chandan Sriraghuramapura Narayanaswamy, Akhil Shetty, Hari Kishore Bhat
AIM: To determine the level of knowledge and skill of basic life support (BLS) among undergraduate, postgraduate students, and general practitioners with and without regular attendance of the BLS Healthcare Provider course. METHODOLOGY: The study was carried out at two intervals with two groups. A random sample involving undergraduate students, postgraduate students, and dental professionals was selected for both study groups. Group 1 with 440 participants had not attended BLS for Healthcare Providers Course in the last two years...
2024: National Journal of Maxillofacial Surgery
https://read.qxmd.com/read/38687076/antimicrobial-activity-of-ceftazidime-avibactam-against-kpc-2-producing-enterobacterales-a-cross-combination-and-dose-escalation-titration-study-with-relebactam-and-vaborbactam
#8
JOURNAL ARTICLE
Min Seo Kang, Jin Yang Baek, Jae-Hoon Ko, Sun Young Cho, Keon Young Lee, Young Ho Lee, Jinyoung Yang, Tae Yeul Kim, Hee Jae Huh, Nam Yong Lee, Kyungmin Huh, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck
UNLABELLED: With the introduction of ceftazidime-avibactam worldwide, the antimicrobial activity of new β-lactam/β-lactamase inhibitors (BL/BLIs) needs to be investigated. From January 2020 to June 2023, Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacterales were collected. With a broth microdilution test of new BL/BLIs, cross-activity test with nine combinations of BLs and new BLIs and dose-escalation titration test for non-susceptible isolates were conducted to investigate inhibitory activities of new BLIs...
April 30, 2024: Microbiology Spectrum
https://read.qxmd.com/read/38684939/comparative-transcriptomic-profiling-of-the-two-stage-response-of-rice-to-xanthomonas-oryzae-pv-oryzicola-interaction-with-two-different-pathogenic-strains
#9
COMPARATIVE STUDY
Yunya Bi, Yue Yu, Shuaige Mao, Tao Wu, Tao Wang, Ying Zhou, Kabin Xie, Hua Zhang, Li Liu, Zhaohui Chu
BACKGROUND: Two-tiered plant immune responses involve cross-talk among defense-responsive (DR) genes involved in pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI), effector-triggered immunity (ETI) and effector-triggered susceptibility (ETS). Bacterial leaf streak (BLS), caused by Xanthomonas oryzae pv. oryzicola (Xoc) is an important bacterial disease that causes serious threats to rice yield and quality. Transcriptomic profiling provides an effective approach for the comprehensive and large-scale detection of DR genes that participate in the interactions between rice and Xoc...
April 29, 2024: BMC Plant Biology
https://read.qxmd.com/read/38684157/-resuscitation-update-what-s-new
#10
REVIEW
Jan-Thorsten Gräsner, Stephan Katzenschlager, Leonie Hannappel, Jan Wnent
Perfect, uninterrupted basic life support (BLS) is the key for successful cardiopulmonary resuscitation (CPR) in out-of-hospital cardiac arrest (OHCA). Time plays an important role in the treatment of OHCA. This applies both to the time until the start of BLS and the reduction of all pauses during resuscitation, especially chest compressions. In 2022, the rate of bystander-CPR showed an absolute increase of 4% compared to previous years. The bystander-CPR rate is currently above 50%. Compared to OHCA in adults, cardiac arrest in children is rare in Germany...
April 2024: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
https://read.qxmd.com/read/38682795/auditing-the-prescription-drug-consumer-price-index-in-a-changing-marketplace
#11
JOURNAL ARTICLE
Andrew L Hicks, Ernst R Berndt, Richard G Frank
Changes in the dynamics of prescription drug markets have raised issues regarding whether the United States Bureau of Labor Statistics' (BLS') Prescription Drug Consumer Price Index (CPI-Rx) has adequately kept up with the evolving marketplace. The CPI-Rx limits its sampling frame to retail outpatient outlets and excludes prescription pharmaceuticals dispensed in non-retail settings such as hospitals, physician/clinic outpatient facilities, and nursing homes. Thus, the CPI-Rx overlooks the increasingly important specialty pharmaceuticals dispensed in non-retail settings, whose transactions are instead captured in the overall hospital and professional services component of the medical care CPI...
April 29, 2024: Health Economics
https://read.qxmd.com/read/38681883/influence-of-the-coronavirus-disease-2019-pandemic-and-bystander-victim-relationship-on-the-willingness-of-laypeople-and-health-care-providers-to-perform-cardiopulmonary-resuscitation
#12
JOURNAL ARTICLE
Suhattaya Boonmak, Thapanawong Mitsungnern, Pimmada Boonmak, Polpun Boonmak
INTRODUCTION: Bystander cardiopulmonary resuscitation (CPR) reduces mortality from out.of.hospital cardiac arrest. The willingness to perform CPR (W-CPR) is also critical. Uncertain effects of the coronavirus disease 2019 (COVID-19) pandemic on W-CPR were reported. Our objectives aim to examine W-CPR during the COVID-19 pandemic, including the influence of the bystander-victim relationship, bystander characteristics, and CPR background on the W-CPR of laypeople and healthcare providers (HCPs)...
2024: Journal of Emergencies, Trauma, and Shock
https://read.qxmd.com/read/38681058/use-of-augmented-and-virtual-reality-in-resuscitation-training-a-systematic-review
#13
REVIEW
Adam Cheng, Nino Fijacko, Andrew Lockey, Robert Greif, Cristian Abelairas-Gomez, Lucija Gosak, Yiqun Lin
OBJECTIVES: To evaluate the effectiveness of augmented reality (AR) and virtual reality (VR), compared with other instructional methods, for basic and advanced life support training. METHODS: This systematic review was part of the continuous evidence evaluation process of the International Liaison Committee on Resuscitation (ILCOR) and reported based on the Preferred Reporting Items for Systematic review and Meta-Analysis (PRISMA) guidelines and registered with PROSPERO (CRD42023376751)...
June 2024: Resuscitation plus
https://read.qxmd.com/read/38679895/applying-self-determination-theory-to-internalized-weight-stigma-and-mental-health-correlates-among-young-and-middle-adult-women-a-structural-equation-model
#14
JOURNAL ARTICLE
Dakota L Leget, Lara J LaCaille, Stephanie A Hooker, Rick A LaCaille, Matthew W Lauritsen
Limited research has explored the relationship between self-determination theory constructs (basic psychological needs, autonomous/controlled regulation) and internalized weight stigma (IWS). This cross-sectional, online study surveyed 480 U.S. women aged 18-40 between 2021 and 2022. We hypothesized that need frustration and controlled weight regulation would relate to higher IWS, which would be associated with dysfunctional eating, distress, and lower life satisfaction. Conversely, we predicted that need satisfaction, autonomous regulation, and body satisfaction would be associated with reduced IWS, dysfunctional eating and distress, and higher life satisfaction...
April 28, 2024: Journal of Health Psychology
https://read.qxmd.com/read/38679671/enhancing-nerve-regeneration-in-infraorbital-nerve-injury-rat-model-effects-of-vitamin-b-complex-and-photobiomodulation
#15
JOURNAL ARTICLE
Daniel Oliveira Martins, Daniel Pereira Marques, Marucia Chacur
Orofacial nerve injuries may result in temporary or long-term loss of sensory function and decreased quality of life in patients. B vitamins are required for DNA synthesis and the repair and maintenance of phospholipids. In particular, vitamins B1, B6, and B12 are essential for neuronal function. Deficiency in vitamin B complex (VBC) has been linked to increased oxidative stress, inflammation and demyelination. Photobiomodulation (PBM) has antioxidant activity and is neuroprotective. In addition, a growing literature attests to the positive effects of PBM on nerve repair...
April 29, 2024: Lasers in Medical Science
https://read.qxmd.com/read/38676481/development-of-cell-and-gene-therapies-for-clinical-use-in-the-us-and-eu-summary-of-regulatory-guidelines
#16
JOURNAL ARTICLE
Anand Rotte
Recent decades have seen advancements in the management and treatment of difficult-- to-treat diseases such as cancer. A special class of therapeutics called cell and gene therapy has been introduced in the past 10 years. Cell and gene therapy products have strengthened the treatment options for life-threatening diseases with unmet clinical needs and also provided the possibility of a potential cure for the disease in some of the patients. Cell and gene therapy products are gaining recognition, and the interest in clinical development of cell and gene therapy products is increasing...
April 25, 2024: Current Gene Therapy
https://read.qxmd.com/read/38673532/a-study-on-the-sense-of-parental-competence-health-locus-of-control-and-levels-of-anxiety-depression-and-somatization-in-parents-of-children-with-type-1-diabetes-evidence-on-a-possible-relationship
#17
JOURNAL ARTICLE
Ivonne Carosi Arcangeli, Giovanna Celia, Laura Girelli, Chiara Fioretti, Mauro Cozzolino
Background : Parents of children with chronic conditions face challenges that go beyond basic care and parenting responsibilities. Parents' experiences can be influenced by perceived stress, emotional experiences, feelings of helplessness, low sense of self-efficacy, anxiety and depression, reducing their quality of life. It is therefore not surprising that parents of children with chronic illnesses are more likely to experience stress, anxiety and depression than parents of healthy children. A prevalent chronic condition is type 1 diabetes...
April 13, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38672770/are-gender-differences-important-for-autoimmune-liver-diseases
#18
REVIEW
Annarosa Floreani, Daniela Gabbia, Sara De Martin
Gender Medicine has had an enormous expansion over the last ten years. Autoimmune liver diseases include several conditions, i.e., autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), and conditions involving the liver or biliary tree overlapping with AIH, as well as IgG4-related disease. However, little is known about the impact of sex in the pathogenesis and natural history of these conditions. The purpose of this review is to provide an update of the gender disparities among the autoimmune liver diseases by reviewing the data published from 1999 to 2023...
April 12, 2024: Life
https://read.qxmd.com/read/38667658/the-exploitation-of-sodium-deoxycholate-stabilized-nano-vesicular-gel-for-ameliorating-the-antipsychotic-efficiency-of-sulpiride
#19
JOURNAL ARTICLE
Marwa H Abdallah, Mona M Shahien, Alia Alshammari, Somaia Ibrahim, Enas Haridy Ahmed, Hanan Abdelmawgoud Atia, Hemat A Elariny
The present study explored the effectiveness of bile-salt-based nano-vesicular carriers (bilosomes) for delivering anti-psychotic medication, Sulpiride (Su), via the skin. A response surface methodology (RSM), using a 33 Box-Behnken design (BBD) in particular, was employed to develop and optimize drug-loaded bilosomal vesicles. The optimized bilosomes were assessed based on their vesicle size, entrapment efficiency (% EE), and the amount of Sulpiride released. The Sulpiride-loaded bilosomal gel was generated by incorporating the optimized Su-BLs into a hydroxypropyl methylcellulose polymer...
March 31, 2024: Gels
https://read.qxmd.com/read/38666255/do-laypersons-need-app-linked-real-time-feedback-devices-for-effective-resuscitation-results-of-a-prospective-randomised-simulation-trial
#20
JOURNAL ARTICLE
Sabine Wingen, Nele Großfeld, Niels-Benjamin Adams, Antonia Streit, Jan Stock, Bernd W Böttiger, Wolfgang A Wetsch
BACKGROUND: App-linked real-time feedback-devices for cardiopulmonary resuscitation (CPR) aim to improve laypersons' resuscitation quality. Resuscitation guidelines recommend these technologies in training settings. This is the first study comparing resuscitation quality of all App-linked feedback-devices currently on market. METHODS: A prospective randomised simulation study was performed. After standardised instructions, participants performed 2-minutes compression-only CPR on a manikin without feedback (baseline)...
June 2024: Resuscitation plus
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