Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#21
JOURNAL ARTICLE
Risimati E Rikhotso, Mmathabo G Sekhoto
AIM: To evaluate and compare outcomes of patients with temporomandibular joint ankylosis (TMJA) treated by gap arthroplasty, costochondral graft, and total alloplastic joint reconstruction. METHODOLOGY: A retrospective cohort study reviewed and analyzed data from patients with TMJA from January 1, 2009 to December 31, 2019, at the Maxillofacial and Oral Surgery Department, University of the Witwatersrand. Patients with TMJA were treated either with gap arthroplasty, costochondral graft, or total alloplastic joint reconstruction...
May 14, 2024: Journal of Craniofacial Surgery
#22
JOURNAL ARTICLE
Oliver Davidson, Anand E Rajesh, Marian Blazes, Ashley Batchelor, Aaron Y Lee, Cecilia S Lee, Laura C Huang
PURPOSE: Understanding sociodemographic factors associated with poor visual outcomes in children with juvenile idiopathic arthritis-associated uveitis may help inform practice patterns. PATIENTS AND METHODS: Retrospective cohort study on patients <18 years old who were diagnosed with both juvenile idiopathic arthritis and uveitis based on International Classification of Diseases tenth edition codes in the Intelligent Research in Sight Registry through December 2020...
2024: Clinical Ophthalmology
#23
JOURNAL ARTICLE
Artemis Koutsonikoli, Anna Taparkou, Polyxeni Pratsidou-Gertsi, Vasiliki Sgouropoulou, Maria Trachana
OBJECTIVES: To investigate the immunoregulatory role of the Programmed-cell-Death-protein-1 (PD1) pathway, an inhibitory immune checkpoint, in Juvenile Idiopathic Arthritis (JIA). METHODS: The PD1 expression on CD4+ and CD8+ T-cells was determined by flow cytometry and the PD1 soluble form (sPD1) levels by ELISA, in peripheral blood (PB)/serum and synovial fluid (SF) samples of JIA patients and healthy controls (HCs). We searched for any association in-between the biomarkers and with JIA activity...
March 2024: Mediterranean journal of rheumatology
#24
REVIEW
Yuanji Dong, Ting Wang, Huaxiang Wu
Macrophage activation syndrome (MAS) is a rare complication of autoimmune inflammatory rheumatic diseases (AIIRD) characterized by a progressive and life-threatening condition with features including cytokine storm and hemophagocytosis. Predisposing factors are typically associated with microbial infections, genetic factors (distinct from typical genetically related hemophagocytic lymphohistiocytosis (HLH)), and inappropriate immune system overactivation. Clinical features include unremitting fever, generalized rash, hepatosplenomegaly, lymphadenopathy, anemia, worsening liver function, and neurological involvement...
2024: Frontiers in Immunology
#25
JOURNAL ARTICLE
Pierre Quartier
No abstract text is available yet for this article.
May 11, 2024: Rheumatology
#26
JOURNAL ARTICLE
Katarzyna Kapten, Krzysztof Orczyk, Anna Maeser, Elzbieta Smolewska
Background : As the SARS-CoV-2 virus remains one of the main causes of severe respiratory system infections, the Food and Drug Administration strongly advises the continuation of current vaccination programs, including the distribution of updated boosters, especially in high-risk groups of patients. Therefore, there is an unceasing need for further research on the safety and, no less importantly, the clinical effectivity of the vaccines, with an extra focus on cohorts of patients with underlying health problems...
April 25, 2024: Journal of Clinical Medicine
#27
RANDOMIZED CONTROLLED TRIAL
Bastiaan T van Dijk, Sytske Anne Bergstra, J Merlijn van den Berg, Dieneke Schonenberg-Meinema, Lisette W A van Suijlekom-Smit, Marion A J van Rossum, Yvonne Koopman-Keemink, Rebecca Ten Cate, Cornelia F Allaart, Daniëlle M C Brinkman, Petra C E Hissink Muller
BACKGROUND: Etanercept has been studied in doses up to 0.8 mg/kg/week (max 50 mg/week) in juvenile idiopathic arthritis (JIA) patients. In clinical practice higher doses are used off-label, but evidence regarding the relation with outcomes is lacking. We describe the clinical course of JIA-patients receiving high-dose etanercept (1.6 mg/kg/week; max 50 mg/week) in the BeSt for Kids trial. METHODS: 92 patients with oligoarticular JIA, RF-negative polyarticular JIA or juvenile psoriatic arthritis were randomised across three treat-to-target arms: (1) sequential DMARD-monotherapy (sulfasalazine or methotrexate (MTX)), (2) combination-therapy MTX + 6 weeks prednisolone and (3) combination therapy MTX + etanercept...
May 10, 2024: Pediatric Rheumatology Online Journal
#28
JOURNAL ARTICLE
Abdulaziz Boqaeid, Laila Layqah, Amgad Alonazy, Mutaz Althobaiti, Al-Zahraa Almahlawi, Abdullah Al-Roqy, Omar Baharoon, Abdullah Alsaeedi, Jinan Shamou, Salim Baharoon
BACKGROUND: The risk of infection including tuberculosis (TB) infection or reactivation during biological therapy with the current various clinical application is a major concern. This risk may be higher in countries endemic to TB. Our aim of this study is to determine the risk of TB infection in patients receiving 3 biological treatments, Adalimumab, Etanercept and Tocilizumab. METHODS: A retrospective cohort study extending over 2 years follow-up for all patients receiving Adalimumab, Etanercept and Tocilizumab for various clinical indications in a tertiary care center in Saudi Arabia...
April 21, 2024: Journal of Infection and Public Health
#29
JOURNAL ARTICLE
Pablo Mesa-Del-Castillo, Inés Yago Ugarte, J M Bolarín, David Martínez, Berta López Montesinos, Honorio Barranco González, Inmaculada Calvo Penadés, Lucia Lacruz Pérez, Daniel Clemente, Juan Carlos Robledillo, Isabel Valls Ferrán, Beatriz Bravo Mancheño, Marina Rubio Plats, Laura Martín Pedraz, Carmen Alba Linero, Belén Sevilla-Pérez, J L García-Serrano, Maria Concepcion Mir-Perelló, Noelia Druetta, Alex Souto, Fernando Lopez-Lopez, Cristina Zarallo-Reales, María Jerez Fidalgo, Jorge Solana Fajardo, Natalia Palmou Fontana, Rosalia Demetrio Pablo, Mari Carmen Pinedo, Alex Fonollosa, Vega Jovani Casano, Jose Juan Mondejar García, Anahy Brandy, Alba García López, M Esteban-Ortega, Teresa Reinoso, Joan Calzada-Hernández, Ana Llorca Cardeñosa, César Gavilán Martín, Encarna Mengual Verdú, Mari Paz Martínez Vidal, Neus Quilis Martí, M C Alvarado, Jaime De Inocencio, Beatriz Alonso-Martín, Sheila Recuero-Diaz, Ester Carreño, Juan Carlos Nieto González, Lucia Ibares, Jose Rosas Gómez de Salazar, Juan Luis Sánchez Sevila
OBJECTIVE: To characterize and describe clinical experience with childhood-onset non-infectious uveitis. STUDY DESIGN: A multicenter retrospective multidisciplinary national web-based registry of 507 patients from 21 hospitals was analyzed. Cases were grouped as immune disease-associated (IMDu), idiopathic (IDIu) or ophthalmologically distinct. Characteristics of juvenile idiopathic arthritis-associated (non-HLA-B27-related) uveitis (JIAu), IDIu, and pars planitis (PP) were compared...
May 10, 2024: Ocular Immunology and Inflammation
#30
JOURNAL ARTICLE
Han Zhang, Xiao Ma, Wanlu Liu, Ze Wang, Zian Zhang, GuanHong Chen, Yingze Zhang, Tianrui Wang, Tengbo Yu, Yongtao Zhang
BACKGROUND: Juvenile Idiopathic Arthritis (JIA) is a condition that occurs when individuals under the age of 16 develop arthritis that lasts for more than six weeks, and the cause is unknown. The development of JIA may be linked to serum metabolites. Nevertheless, the association between JIA pathogenesis and serum metabolites is unclear, and there are discrepancies in the findings across studies. METHODS: In this research, the association between JIA in humans and 486 serum metabolites was assessed using genetic variation data and genome-wide association study...
May 9, 2024: Pediatric Rheumatology Online Journal
#31
JOURNAL ARTICLE
Emma Rezel-Potts, Catherine Bowen, Kate M Dunn, Christopher I Jones, Martin C Gulliford, Stewart C Morrison
The aim of this research was to describe the epidemiology, presentation and healthcare use in primary care for foot and ankle problems in children and young people (CYP) across England. We undertook a population-based cohort study using data from the Clinical Practice Research Datalink Aurum database, a database of anonymised electronic health records from general practices across England. Data was accessed for all CYP aged 0-18 years presenting to their general practitioner between January 2015 and December 2021 with a foot and/or ankle problem...
May 9, 2024: European Journal of Pediatrics
#32
JOURNAL ARTICLE
Mie Fusama, Hideko Nakahara, Takako Miyamae, Masaaki Mori, Yukitomo Urata, Kimito Kawahata, Yutaka Kawahito, Masayo Kojima, Takahiko Sugihara, Motomu Hashimoto, Atsuko Murashima, Nobuyuki Yajima, Toshihiro Matsui
OBJECTIVES: This study aimed at identifying challenges nurses face in caring for patients with juvenile idiopathic arthritis (JIA) in Japan. METHODS: Nurses certified by the Japan Rheumatism Foundation were asked to describe their challenges with caring for JIA patients. Data was analyzed using qualitative content analysis. RESULTS: Responses were collected from 89 participants. 58 issues were identified from 40 participants with experience caring for JIA patients...
May 6, 2024: Modern Rheumatology
#33
JOURNAL ARTICLE
Sean Hideo Shirata Lanças, Matheus Zanata Brufatto Furlan, Taciana de Albuquerque Pedrosa Fernandes, Sula Glaucia Lage Drumond, Claudia Saad Magalhães
BACKGROUND: Juvenile idiopathic arthritis (JIA) comprises a whole spectrum of chronic arthritis starting before 16 years of age. The study aims to explore the clinical and demographic descriptors, treatment, and disease progression of enthesitis-related arthritis (ERA) in comparison with juvenile-onset spondyloarthritis (SpA). METHODS: Cross-sectional analysis of consecutive patients in two dedicated clinics, with a single visit and retrospective case-notes review...
May 8, 2024: Advances in Rheumatology
#34
JOURNAL ARTICLE
Marwan H Adwan, Ula Qasem, Saed Y Atawnah, Muath Itmeizeh, Rifaat Hanbali, Najla Ali Alsoofi, Mohammed Abu Jbara, Ayman AbuHelal, Fatima Alnaimat
This study aims to analyze the clinical and immunologic features of SLE in Jordan, while also investigating the impact of age and gender on disease presentation. The study included 275 patients diagnosed with SLE. Data were collected through meticulous patient interviews and thorough examination of patient hospital records. The cohort exhibited a mean age of 36.8 ± 12.9 years, with an average disease duration of 7.0 ± 7.8 years. The mean age at diagnosis was 29...
May 8, 2024: Rheumatology International
#35
JOURNAL ARTICLE
Julia E Möhlmann, Sytze de Roock, Annelies C Egas, Evelien Ter Weijden, Martijn J H Doeleman, Alwin D R Huitema, Matthijs van Luin, Joost F Swart
BACKGROUND: Low-dose weekly methotrexate (MTX) is the mainstay of treatment in juvenile idiopathic arthritis. Unfortunately, a substantial part of patients has insufficient efficacy of MTX. A potential cause of this inadequate response is suboptimal drug adherence. The aim of this study was to assess MTX adherence in juvenile idiopathic arthritis patients by quantification of MTX concentrations in plasma. Secondly, the association between MTX concentrations and either self-reported adherence issues, or concomitant use of biologics was examined...
May 7, 2024: Pediatric Rheumatology Online Journal
#36
JOURNAL ARTICLE
Philip Brenner, Johan Askling, David Hägg, Lena Brandt, Paul Stang, Johan Reutfors
OBJECTIVE: To investigate whether the association between depression and inflammatory joint disease (IJD; rheumatoid arthritis [RA], psoriatic arthritis [PsA], ankylosing spondylitis/spondyloarthropathies [AS], and juvenile idiopathic arthritis [JIA]) is affected by the severity or treatment-resistance of depression. METHOD: Parallel cohort studies and case-control studies among 600,404 patients with a depressive episode identified in Swedish nationwide administrative registers...
April 27, 2024: General Hospital Psychiatry
#37
JOURNAL ARTICLE
Ai Tien Nguyen, Antoine Rousseau, Bahram Bodaghi, Linda Rossi-Semerano, Caroline Galeotti, Elodie Da Cunha, Laura Eid, Marc Labetoulle, Emmanuel Barreau, Cherif Titah, Adélaïde Toutée, Isabelle Koné-Paut, Perrine Dusser, Charlotte Borocco
INTRODUCTION: Paediatric granulomatous uveitis (PGU) is rare. In addition, lack of awareness often leads to delayed diagnosis and poor visual outcome. Identifying the underlying cause and deciding how best to treat each patient is challenging. OBJECTIVES: To evaluate the demographics, aetiologies, complications, treatments, and visual prognosis of paediatric non-infectious granulomatous uveitis. METHODS: Retrospective chart review of non-infectious PGU occurring in children before the age of 16 years recruited from the Paediatric Rheumatology Unit, Bicêtre Hospital, France, from 2001 to 2023...
May 6, 2024: Rheumatology
#38
COMPARATIVE STUDY
Baoquan Wang, Yushan Zhang, Zhenbiao Zhao, Juan Ping, Liming Zhou, Yining Wang, Yongzhou Zhang
BACKGROUND: The goal of this study was to estimate the relative efficacy and safety of different biological agents (infliximab, canakinumab, baricitinib, anakinra, adalimumab, tofacitinib, tocilizumab, and rilonacept) compared with placebo for systemic juvenile idiopathic arthritis (JIA) patients, through a network meta-analysis. METHODS: Pubmed, Embase, and Cochrane Library were searched from database inception to July 2023 for randomized controlled trials comparing different biological agents (infliximab, canakinumab, baricitinib, anakinra, adalimumab, tofacitinib, tocilizumab, and rilonacept) or placebo directly or indirectly in JIA...
May 3, 2024: Medicine (Baltimore)
#39
JOURNAL ARTICLE
Laura Scagnellato, Giacomo Cozzi, Ilaria Prosepe, Mariagrazia Lorenzin, Andrea Doria, Giorgia Martini, Francesco Zulian, Roberta Ramonda
INTRODUCTION: Our aim was to describe a monocentric cohort of young adult patients with juvenile idiopathic arthritis (JIA), assessing the risk of relapse after transition to adult care. METHODS: We conducted a retrospective study and collected clinical, serological, and demographic data of young adult patients (18-30 years old) referred to the Transition Clinic of a single Italian centre between January 2020 and March 2023. Patients with systemic-onset JIA were excluded...
2024: PloS One
#40
Maha Abdalla Yahia Elhassan, Roua Mohammedali Hussain Idres, Baraa Mohamed Salaheldin Mohamed Elhassan, Naema Siddiq Banaga Siddiq, Rayan Abdelwahab Osman Mohammed, Mohammed Mahmmoud Fadelallah Eljack, Ghassan E Mustafa, Lina Hemmeda, Khabab Abbasher Hussien Mohamed Ahmed
INTRODUCTION AND IMPORTANCE: Macrophage activation syndrome (MAS) is a severe form of hemophagocytic lymphohistiocytosis that is frequently associated with either a flare-up of rheumatologic diseases, or infection and is characterized by intermittent fever, organomegaly, and multisystem dysfunction. Early diagnosis and treatment are crucial for outcome improvement. CASE PRESENTATION: The authors present a 9-year-old male with systemic onset juvenile idiopathic arthritis who presented with fever, vomiting, and nose bleeding, as well as being jaundiced, and having hepatomegaly and ascites...
May 2024: Annals of Medicine and Surgery
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
