Christopher P Fagundes, Ronald Glaser, Sheri L Johnson, Rebecca R Andridge, Eric V Yang, Michael P Di Gregorio, Min Chen, David R Lambert, Scott D Jewell, Mark A Bechtel, Dean W Hearne, Joel B Herron, Janice K Kiecolt-Glaser
CONTEXT: Child emotional maltreatment can result in lasting immune dysregulation that may be heightened in the context of more recent life stress. Basal cell carcinoma (BCC) is the most common skin cancer, and the immune system plays a prominent role in tumor appearance and progression. OBJECTIVE: To address associations among recent severe life events, childhood parental emotional maltreatment, depression, and messenger RNA (mRNA) coding for immune markers associated with BCC tumor progression and regression...
June 2012: Archives of General Psychiatry