Ana Guzmán-Carrasco, Garyfallia Kapravelou, María López-Jurado, Francisco Bermúdez, Eduardo Andrés-León, Laura C Terrón-Camero, José Prados, Consolación Melguizo, Jesus M Porres, Rosario Martínez
The prevalence of obesity increases alarmingly every year mostly due to external factors such as high-fat and high-refined sugar intake associated with a sedentary lifestyle. It triggers metabolic disorders such as insulin resistance, hyperlipemia, non-alcoholic fatty liver disease, chronic inflammation, oxidative stress, and gut microbiota dysbiosis. The aim of this study was to evaluate the beneficial effects of a combined intervention with caloric restriction, nutraceutical intake, and a mixed training protocol on oxidative stress, inflammation, and gut dysbiosis derived from the development of obesity in a C57BL6/J mouse experimental model of diet-induced obesity (4...
February 23, 2024: Antioxidants (Basel, Switzerland)