Dou Yuan, Ke Lin, Yuanning Xu
BACKGROUND: High-grade atrioventricular block is the primary reason for epicardial permanent pacemaker implantation during the perioperative period in patients with congenital heart disease. Due to the smaller diameter of venous vessels in children, epicardial permanent pacemaker implantation is usually a preferred choice, we report one pediatric patient who received epicardial permanent pacemaker implantation using a new approach. CASE PRESENTATION: We present the case of a 2-year-old girl who underwent the modified Konno procedure and Pulmonary valvuloplasty surgery and presented after surgery with a High-grade atrioventricular block...
July 20, 2024: Journal of Cardiothoracic Surgery
Goeto Dantes, Olivia A Keane, Louis Do, Savanah Rumbika, Nathaniel H Ellis, Valerie L Dutreuil, Zhulin He, Amina M Bhatia
PURPOSE: Spontaneous intestinal perforation (SIP) and necrotizing enterocolitis (NEC) are distinct disease processes associated with significant morbidity and mortality. Initial treatment, laparotomy (LP) versus peritoneal drainage (PD), is disease specific however it can be difficult to distinguish these diagnoses preoperatively. We investigated clinical characteristics associated with each diagnosis and constructed a scoring algorithm for accurate preoperative diagnosis. METHODS: A cohort of extreme and very low birth weight (<1500 g) neonates surgically treated for SIP or NEC between 07/2004-09/2022 were reviewed...
June 28, 2024: Journal of Pediatric Surgery
Alice E Huang, Tulio A Valdez
Artificial intelligence (AI) studies show how to program computers to simulate human intelligence and perform data interpretation, learning, and adaptive decision-making. Within pediatric otolaryngology, there is a growing body of evidence for the role of AI in diagnosis and triaging of acute otitis media and middle ear effusion, pediatric sleep disorders, and syndromic craniofacial anomalies. The use of automated machine learning with robotic devices intraoperatively is an evolving field of study, particularly in the realms of pediatric otologic surgery and computer-aided planning for maxillofacial reconstruction, and we will likely continue seeing novel applications of machine learning in otolaryngologic surgery...
July 19, 2024: Otolaryngologic Clinics of North America
Yıldız S, Inanç I, Zhuri D, Atlı E, Avlan D
INTRODUCTION: Hypospadias is a common malformation of the genitourinary system and is thought with a complex interplay between genetics and environmental factors likely contributing to its pathogenesis. This study aimed to investigate the receptor gene expressions of sex hormones, FGFR2, FGF8 and BMP7 and DNA methylations in these genes as an epigenetic mark, which may play a role in the etiology of hypospadias. MATERIAL AND METHODS: The samples from the foreskin of 20 patients with hypospadias and 20 healthy children who underwent circumcision operations were collected...
July 10, 2024: Journal of Pediatric Urology
Molly E Fuchs, Shruthi Srinivas, Raquel Quintanilla Amoros, Venkata R Jayanthi, Richard J Wood, Daniel G Dajusta
BACKGROUND: Girls with cloacal malformation are at risk of bladder dysfunction, with nearly 90% exhibiting some degree of dysfunction. Surgical dissection, particularly with total urogenital mobilization (TUM), has been hypothesized as a cause of worsening bladder function despite this population commonly having associated vertebral and spinal cord abnormalities that may also explain bladder dysfunction. More recently there has been great effort to select the appropriate surgical technique for cloacal repair in each patient in order to minimize dissection and potential damage to the bladder...
July 10, 2024: Journal of Pediatric Urology
Jennifer R Marin, Todd W Lyons, Ilene Claudius, Mary E Fallat, Michael Aquino, Timothy Ruttan, Reza J Daugherty
Advanced imaging, including ultrasonography, computed tomography, and magnetic resonance imaging (MRI), is an integral component to the evaluation and management of ill and injured children in the emergency department. As with any test or intervention, the benefits and potential impacts on management must be weighed against the risks to ensure that high-value care is being delivered. There are important considerations specific to the pediatric patient related to the ordering and interpretation of advanced imaging...
August 2024: Annals of Emergency Medicine
A Vicente, Amparo Pérez-Ferriols, Ana Batalla, Laura García-Fernandez, Beatriz Pérez, N Eiris, R de Lucas, P De La Cueva, J M Carrascosa
Justification and objectives: The Spanish Academy of Dermatology and Venereology (AEDV) Psoriasis and Pediatric Working Groups (PSW and PWG) have developed a set of recommendations for the management of pediatric psoriasis based on the best available evidence and experts' opinion. Methodology: The methodology of nominal groups was followed, with help from a scoping review. A coordinator was designated, and a group of experts was selected based on their experience and knowledge on the management of psoriasis...
July 18, 2024: Actas Dermo-sifiliográficas
A Torrelo Fernández, A Vicente, A Martin-Santiago, R de Lucas Laguna, J C Armario-Hita, R Moro, S Díaz-Cerezo, L Lizán, M Núñez
Atopic dermatitis (AD) is a chronic, inflammatory skin disease affecting all age groups, particularly children. This systematic review provides an overview of the humanistic and economic disease burden in the pediatric population with AD in Spain. The evidence, collected from 11 observational studies published over the past 10 years, exhibits the most common characteristics of the patients, disease burden, patient-reported outcomes, use of resources, and treatment patterns. The burden of AD extends beyond physical symptoms, with associated comorbidities such as asthma and impaired health-related quality of life and mental health disorders, particularly in severe cases...
July 18, 2024: Actas Dermo-sifiliográficas
M Colmenero-Sendra, J Del Boz-González, E Baselga Torres, J Bernabéu-Wittel, E Roé-Crespo, A Vicente, M Valdivieso-Ramos, A Martín-Santiago, S I Palencia-Pérez, M T Montserrat-García, A Azón-Masoliver, M Dañino, Carla Tubau Prims, C Prat, A Giacaman, J J Domínguez-Cruz, A Bauzá Alonso, M Grau-Pérez, M Á Descalzo, I García-Doval
BACKGROUND: Functional impairment is the main consideration when it comes to choosing therapy for infantile hemangiomas (IH). However, since most hemangiomas are treated for cosmetic reasons, it is important to know the cosmetic outcome assessed by the parents. OBJECTIVE: To evaluate the aesthetic outcomes of IH, considering the characteristics of the lesions and the treatments used. PATIENTS AND METHODS: The Spanish Infantile Hemangioma Nationwide Prospective Cohort (2016-2022) recruited all consecutive patients diagnosed with IH in 12 Spanish hospitals...
July 18, 2024: Actas Dermo-sifiliográficas
William E Benitz, Richard A Polin
No abstract text is available yet for this article.
July 18, 2024: Journal of Pediatrics
Tarina Parpia, Sarah Elwood, Elizabeth T Rogawski McQuade, Erling Svensen, Anne Wanjuhi, Samwel Jatosh, Eliwaza Bayo, Emanuel Hhando, Eric R Houpt, Estomih Mduma, Mark D DeBoer, Rebecca J Scharf, James A Platts-Mills
OBJECTIVE: To evaluate in a rural Tanzanian birth cohort the association between birth timing in relation to the pre-harvest lean season and early-life growth and cognitive development STUDY DESIGN: Children were enrolled within 14 days of birth and followed for 18 months. Child anthropometry was measured every three months. The Malawi Developmental Assessment Test (MDAT) was administered at the end of follow-up. We estimated the association between timing of birth in the context of other early childhood risk factors and both growth and MDAT scores...
July 18, 2024: Journal of Pediatrics
Marilena Savoia, Eva Busolini, Daniel Ibarra Rios, Brady Thomas, J Lauren Ruoss, Patrick J McNamara
No abstract text is available yet for this article.
July 18, 2024: Journal of Pediatrics
Kevin Michael Cook, Josepheen De Asis-Cruz, Chloe Sitrin, Scott D Barnett, Dhineshvikram Krishnamurthy, Catherine Limperopoulos
OBJECTIVE: To determine the association between neighborhood disadvantage and functional brain development of in utero fetuses. STUDY DESIGN: We conducted an observational study utilizing Social Vulnerability Index (SVI) scores to assess the impact of neighborhood disadvantage on a prospectively recruited sample of healthy pregnant women from Washington, DC. Utilizing 79 functional MRI scans from 68 healthy pregnancies at a mean gestational age of 33.12 weeks, we characterized overall functional brain network structure using a graph metric approach...
July 18, 2024: Journal of Pediatrics
Ping-Chung Wu, Shih-Jen Tsai, Ya-Mei Bai, Ju-Wei Hsu, Tung-Ping Su, Tzeng-Ji Chen, Mu-Hong Chen
BACKGROUND: The mental health of child and adolescent intensive care unit (ICU) survivors is increasingly being researched. However, the literature on how various types of critical illness influence specific psychiatric disorders remains limited. METHODS: This study analyzed the data of 8704 child and adolescent ICU survivors and 87,040 age-, sex-, family income-, and residence-matched controls who were followed from enrollment to the end of 2013; the data covered the period from 1996 to 2013 and were extracted from a nationwide data set...
July 19, 2024: Journal of Affective Disorders
Allison Silverstein, Veronica Easton, Cory Barrows, Kimberly Sawyer, Rachel Coughlin, Nidhi Mali, Amber Kessler, Matthew Robinson, Erica Sirrine, Madison Spears, Jordan Wrigley, Justin N Baker, Erica C Kaye
CONTEXT: Children are a uniquely vulnerable patient population with restricted abilities for self-advocacy and autonomy, risking infringement upon their dignity. Yet the concept of dignity in pediatrics remains underexplored relative to the adult literature and other outcome measures. OBJECTIVES: To characterize how dignity is defined, evaluated, and/or measured in pediatrics. METHODS: We conducted a systematic review following PRISMA guidelines across the following databases: MEDLINE, Embase, Cumulative Index of Nursing and Allied Health, PsycINFO, Global Health, Social Science Premium Collection, and Dissertation and Theses...
July 18, 2024: Journal of Pain and Symptom Management
Keisha White Makinde, Allison Silverstein, Erin Peckham-Gregory, Erin Kim, Jessica Casas
CONTEXT: Children from marginalized groups are at risk for worse medical outcomes, yet little is known about their end of life experiences. OBJECTIVE: We examine the characteristics of deceased children with a focus on race, ethnicity, and preferred language. METHODS: We conducted a cross-sectional study of patients who died at Texas Children's Hospital from 2018-2019. Demographics, date of death, and final code status were extracted. Medical complexity prior to admission and mode of death were obtained from chart review...
July 18, 2024: Journal of Pain and Symptom Management
Alice Lang Silva, Isadora Martins da Silva Stumpf, Laura Prolla Lacroix, Debora Milena Ferreira Alves, Adriana Laybauer da Silveira, Sady Selaimen da Costa, Letícia Petersen Schmidt Rosito
OBJECTIVE: To evaluate the rate of loss to follow-up in a cochlear implant program from the public health system in Southern Brazil as well as the characteristics of hearing loss, sociodemographic, sociocultural and the development of oral language in children with prelingual deafness. METHODS: Retrospective cohort study with children who underwent CI surgery between 2010 and 2020. Data was collected through of interviews and review of medical records. The language development assessment was performed using the MUSS, MAIS and IT-MAIS scales...
June 17, 2024: Brazilian Journal of Otorhinolaryngology
Sydney Peters, Kristen Sportiello, Shreya Mandalapu, Ashlie Nguyen, Ryan Carrier, Carolyn Dickinson, Alex Paciorkowski, David Bearden
BACKGROUND: ZC4H2-associated rare disorder (ZARD) is caused by pathogenic variations in the ZC4H2 gene on the X chromosome. This gene codes for a zinc finger protein involved in neural development. ZARD is characterized by highly variable symptoms, potentially influenced by the sex of the individual. METHODS: The ZC4H2-Associated Rare Disorder Natural History Study is a prospective natural history study conducted among individuals with ZARD that consists of standardized interviews, developmental assessments, and neurological examinations conducted every six months for two years...
June 24, 2024: Pediatric Neurology
Aleksandra Gostyńska, Kamila Buzun, Izabela Żółnowska, Violetta Krajka-Kuźniak, Dorota Mańkowska-Wierzbicka, Anna Jelińska, Maciej Stawny
Parenteral nutrition (PN) is a life-saving procedure conducted to maintain a proper nutritional state in patients with severe intestinal failure who cannot be fed orally. A serious complication of PN therapy is liver failure, known as intestinal failure-associated liver disease (IFALD). The pathogenesis of IFALD is multifactorial and includes inhibition of the farnesoid X receptor (FXR) by PN components, bacteria translocation from impaired intestines, and intravenous line-associated bloodstream infection. Currently, the most frequently researched therapeutic option for IFALD is using lipid emulsions based on soy or fish oil and, therefore, free from phytosterols known as FXR antagonists...
July 14, 2024: Clinical Nutrition
Raden Ahmad Dedy Mardani, Zuhratul Hajri, Zurriyatun Thoyibah, Henny Yolanda, Shu-Yu Kuo, Yuh-Kae Shyu, Hui-Chuan Huang
PURPOSE: This study aimed to examine determinants of undernutrition among children under 2 years of age. DESIGN AND METHODS: A matched case-control study design was conducted to recruit 300 mothers comprising 100 mothers with an undernourished child (case group) and 200 mothers with a healthy child (control group). Measurements consisted of demographic characteristics of children data, mother's data, household data, mother's knowledge of child undernutrition, mother's knowledge of nutrition, complementary feeding practices, and undernutrition parameters of the children...
July 2024: Journal for Specialists in Pediatric Nursing: JSPN
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.