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JOURNAL ARTICLE
Hyun Kyung Kim, Kyung Sik Jang, Dong Wook Kim
OBJECTIVE: This study aimed to compare and characterize the safety profiles of new antiseizure medications (ASMs) using a nationwide pharmacovigilance database from a long-term perspective in Korea. METHODS: We reviewed adverse event reports from the Korea Adverse Event Reporting System database between January 2013 and December 2022 for descriptive analysis of six new ASMs (lacosamide, levetiracetam, lamotrigine, oxcarbazepine, topiramate, and zonisamide). We investigated the frequency and characteristics of adverse drug reactions (ADRs) based on the MedDRA terminology, system organ classes, and modified WHO classification...
April 16, 2024: Epilepsy & Behavior: E&B
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JOURNAL ARTICLE
Joy Verbakel, Nynke van der Gaast, Ruurd L Jaarsma
No abstract text is available yet for this article.
May 1, 2024: Pediatric Infectious Disease Journal
#3
JOURNAL ARTICLE
Bushra Afzal, Sriya Roychaudhuri, Mohamed El-Dib, Carmina Erdei
Neonatal meningoencephalitis caused by human parechovirus infection is being increasingly recognized in recent literature. While most cases are postnatally acquired, intrauterine infection is rare, presents early and has a more severe impact on brain health and development. We discuss here an infant born preterm at 34 weeks gestational age, with neonatal course remarkable for severe encephalopathy presenting on day 2 of life due to human parechovirus meningoencephalitis transmitted in utero. Early magnetic resonance brain imaging detected extensive white matter injury and subsequently evolved into multicystic leukoencephalopathy...
May 1, 2024: Pediatric Infectious Disease Journal
#4
JOURNAL ARTICLE
Diego Cruz Vidal, Simon Lee, Stacy P Ardoin, Djhenne Dalmacy, Juan Chaparro, Cristin Blaney, Vilmarie Rodriguez, Amanda Sankar, Shoghik Akoghlanian, Richard Lisciandro, Matthew Washam, Roshini S Abraham, Amy Leber, Meika Eby, Berkeley Bennett, Guliz Erdem
We prospectively analyzed clinical and laboratory characteristics associated with cardiac involvement and severe presentation in multisystem inflammatory syndrome in children. Of 146 patients, 66 (45.2%) had cardiac dysfunction and 26 (17.8%) had coronary artery abnormalities. Lower serum albumin levels, absolute lymphocyte and platelet counts, and elevated ferritin, fibrinogen, d-dimer and interleukin-6 levels were associated with cardiac dysfunction. Possible treatment complications were identified.
May 1, 2024: Pediatric Infectious Disease Journal
#5
JOURNAL ARTICLE
Lucía Ros Dopico, Ejessie Alfonso Barrera, Berta Valero Telleria, Gonzalo Ruiz-Zurita, Mercedes Martinez Moreno
BACKGROUND: Myoelectric prostheses have become the accepted standard of care for pediatric upper-limb amputees. OBJECTIVES: To describe the clinical characteristics and patterns of prosthesis use and to analyze the changes that occur during the growth process of these patients. STUDY DESIGN: This is a longitudinal retrospective study comparing the results of surveys carried out in 2015 and 2022. METHODS: The variables measured included clinical and demographic characteristics, patterns of use, and satisfaction with the prosthesis...
April 18, 2024: Prosthetics and Orthotics International
#6
JOURNAL ARTICLE
César Augusto de Oliveira Souza Filho, Emilton Lima Junior
INTRODUCTION: Myocardial injury due to COVID-19 infection is associated with higher mortality rates, higher intensive care unit admissions, and greater levels of inflammatory and cardiac markers. However, given the smaller number of papers regarding pediatric patients, there is still scarce data about mortality predictors in this population. This study aims to identify independent predictors of in-hospital death among pediatric patients hospitalized with myocardial injury related to COVID-19...
March 31, 2024: Journal of Infection in Developing Countries
#7
JOURNAL ARTICLE
Lauren A DiNardo, Alyssa D Reese, Maya Raghavan, Meagan Sullivan, Michele M Carr
INTRODUCTION: Our study seeks to understand the profiles of otolaryngologists selected by Castle Connolly's Top Doctor list and how this compares to the entire field of otolaryngology. METHODS: Top Doctor lists published in Castle Connolly affiliated magazines were analyzed for Otolaryngology, Otolaryngology/Facial Plastic Surgery, or Pediatric Otolaryngology physicians. Only lists published in 2021 or representing the 2021 Top Doctor lists were analyzed. Of the total 39 partnered magazines, 27 met our criteria...
2024: PloS One
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JOURNAL ARTICLE
Laura D Zambrano, Margaret M Newhams, Regina M Simeone, Amanda B Payne, Michael Wu, Amber O Orzel-Lockwood, Natasha B Halasa, Jemima M Calixte, Pia S Pannaraj, Kanokporn Mongkolrattanothai, Julie A Boom, Leila C Sahni, Satoshi Kamidani, Kathleen Chiotos, Melissa A Cameron, Aline B Maddux, Katherine Irby, Jennifer E Schuster, Elizabeth H Mack, Austin Biggs, Bria M Coates, Kelly N Michelson, Katherine E Bline, Ryan A Nofziger, Hillary Crandall, Charlotte V Hobbs, Shira J Gertz, Sabrina M Heidemann, Tamara T Bradford, Tracie C Walker, Stephanie P Schwartz, Mary Allen Staat, Samina S Bhumbra, Janet R Hume, Michele Kong, Melissa S Stockwell, Thomas J Connors, Melissa L Cullimore, Heidi R Flori, Emily R Levy, Natalie Z Cvijanovich, Matt S Zinter, Mia Maamari, Cindy Bowens, Danielle M Zerr, Judith A Guzman-Cottrill, Ivan Gonzalez, Angela P Campbell, Adrienne G Randolph
Pediatric COVID-19 vaccination is effective in preventing COVID-19-related hospitalization, but duration of protection of the original monovalent vaccine during SARS-CoV-2 Omicron predominance merits evaluation, particularly given low coverage with updated COVID-19 vaccines. During December 19, 2021-October 29, 2023, the Overcoming COVID-19 Network evaluated vaccine effectiveness (VE) of ≥2 original monovalent COVID-19 mRNA vaccine doses against COVID-19-related hospitalization and critical illness among U...
April 18, 2024: MMWR. Morbidity and Mortality Weekly Report
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JOURNAL ARTICLE
Bao-Fu Yu, Xiao-Xue Chen, Jia Liu, Jin-Guang He, Chuang-Chang Dai, Jiao Wei
SUMMARY: Nasal reconstruction in pediatric patient is very challenging and it requires consideration of later nasal development. Herein, we introduce an innovative preauricular free flap pedicled with retrograde vascular (PFFPRV) for pediatric nasal reconstruction. In this PFFPRV technique, the retrograde superficial temporal vessels were used as the flap pedicle. The lateral alar artery and angular vein were used as vessels of the nasal recipient zone. The flap vessels were anastomosed directly to the recipient area vessels without additional vessel transplantation...
April 18, 2024: Plastic and Reconstructive Surgery
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JOURNAL ARTICLE
Letícia R Morimoto, Daisy T Kase, Paola G Esmanhotto, Murilo A Maciel, Ana C L Augusto, Patrick F Catricala, Julia E C Anaya, Sugoto Mukherjee, Artur R C Fernandes, André Y Aihara
Nontraumatic pathologic conditions of the craniovertebral junction encompass a range of conditions affecting the complex anatomy of this region without direct physical injury. These conditions include congenital syndromes that predispose individuals to ligamentous laxity, potentially leading to instability. Additionally, rare but noteworthy cases such as Grisel syndrome, a cause of pediatric torticollis, may arise without a traumatic trigger. Inflammatory diseases, including rheumatoid arthritis, ankylosing spondylitis, and crystal deposition, can lead to cervical instability and spinal cord compression...
May 2024: Radiographics: a Review Publication of the Radiological Society of North America, Inc
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JOURNAL ARTICLE
Hanife Ayşegül Arsoy, Özlem Kara, Murat Keskin
INTRODUCTION: Parallel to the worldwide increase in obesity, the epidemic of chronic liver disease is increasing also in pediatric population. Our aim is to provide a different outlook on the current screening confusion in pediatric non-alcoholic fatty liver disease (NAFLD) with the non-invasive vibration-controlled transient elastography (VCTE) method. MATERIALS AND METHODS: This single-center, cross-sectional, comparative study was performed at the tertiary center, included 95 patients with obesity and 116 controls, both groups were 9-18 years of ages...
April 18, 2024: Journal of Clinical Ultrasound: JCU
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JOURNAL ARTICLE
Arnaud Fernandez, Florence Askenazy, Radia Zeghari, Philippe Auby, Philippe Robert, Susanne Thümmler, Morgane Gindt
IMPORTANCE: Somatic symptoms are a major concern among the pediatric population because of frequency and burden. The association between adverse childhood experiences and somatic symptoms in adults is well established but less is known concerning somatic symptoms in young people. OBJECTIVE: To explore the frequency and intensity of somatic symptoms in children and adolescents exposed to traumatic events. DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study was conducted from January 1 to December 31, 2021, at the Nice Pediatric Psychotrauma Referral Center in Nice, France...
April 1, 2024: JAMA Network Open
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JOURNAL ARTICLE
Ellis J Neufeld
No abstract text is available yet for this article.
April 18, 2024: Blood
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JOURNAL ARTICLE
Nikita Tuli Sood, Celia Godfrey, Daina Krasts, Elle Morrison, Clara Chavez Arana, Stephen J C Hearps, Vicki Anderson, Cathy Catroppa
OBJECTIVE: To evaluate the effectiveness of Cogmed Working Memory Training (Cogmed) in improving working memory (WM) and decision making (DM) in childhood traumatic brain injury (TBI), and any associated increases in functional outcomes such as academic achievement in mathematics, behavior, social skills, and quality of life. METHOD: A randomized controlled trial of the Cogmed (RM version) intervention for children with TBI. A total of 69 children post-TBI were screened for WM impairments, of which 31 eligible participants ( M age : 10...
April 18, 2024: Neuropsychology
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JOURNAL ARTICLE
S Raghuthaman, K Bansal, J A Quadri, V P Mathur, N Tewari, R Morankar
PURPOSE: The purpose of the study was to determine the fluoride (F) and silver (Ag) ions levels in the saliva and urine of healthy children after silver diamine fluoride (SDF) application on dental carious lesions. METHODS: Sixty children (4-6 years with ≥ 3 caries lesions) were recruited from the outpatient department of Pediatric Dentistry. From each child, 3 ml unstimulated saliva samples were collected at baseline, one hour, and 24 h after SDF application...
April 18, 2024: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
#16
JOURNAL ARTICLE
Ruyuan Zhu, Luyao Wang, Ling Zhao, Xiaojing Liu
BACKGROUND: Craniopharyngioma is a common intracranial tumour in children. Clinical manifestations are related to hypothalamic/pituitary deficiencies, visual impairment, and increased intracranial pressure. Defects in pituitary function cause shortages of growth hormone, gonadotropin, corticotropin, thyrotropin, and vasopressin, resulting in short stature, delayed puberty, feebleness, lethargy, polyuria, etc. However, manifestations involving precocious puberty (PP) are rare. CASE REPORT: In both patients, surgical resection was performed after the diagnosis of craniopharyngioma, and breast development occurred postoperatively at one month in one patient and at one year and three months in the other patient...
April 18, 2024: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
#17
JOURNAL ARTICLE
Xinyao Wang, Wenbin Guan, Lei Bao, Qiang Li, Xiaoqiang Wang
PURPOSE: Desmoplastic fibroma (DF) is an uncommon intermediate bone tumor rarely involving the skull with unidentified pathogenesis. We report the first case of pediatric temporoparietal cranial desmoplastic fibroma (DF) with a CTNNB1 gene mutation and review the previous literature. CASE PRESENTATION: A 3-year-old boy had a firm, painless mass on the right temporoparietal region for 22 months. The cranial CT scan showed isolated osteolytic destruction in the outer plate and diploe of the right temporoparietal bone...
April 18, 2024: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
#18
JOURNAL ARTICLE
Michael G Brandel, Jillian H Plonsker, Robert C Rennert, Gautam Produturi, Megana Saripella, Arvin R Wali, Carson McCann, Vijay M Ravindra, David R Santiago-Dieppa, J Scott Pannell, Jeffrey A Steinberg, Alexander A Khalessi, Michael L Levy
INTRODUCTION: Pediatric intracranial aneurysms (IAs) are rare and have distinct clinical profiles compared to adult IAs. They differ in location, size, morphology, presentation, and treatment strategies. We present our experience with pediatric IAs over an 18-year period using surgical and endovascular treatments and review the literature to identify commonalities in epidemiology, treatment, and outcomes. METHODS: We identified all patients < 20 years old who underwent treatment for IAs at our institution between 2005 and 2020...
April 18, 2024: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
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JOURNAL ARTICLE
Baran Can Alpergin, Umit Eroglu, Ömer Mert Özpişkin, Sevde Demiryurek, Fatmanur Gedikli, Mohd Qotaibah Mustafa G Al Khudari, Orhan Beger
PURPOSE: To describe the relation of the sphenoid ridge (SR) with the surrounding anatomical structures in healthy children when approaching the anterior and middle fossae. METHODS: Computed tomography of 180 pediatric patients (90 males / 90 females), aged 1-18 years were included the study. The size of the lesser wing (LW) and the distances of the LW to certain landmarks were measured. RESULTS: The LW length was 28.48 ± 8...
April 18, 2024: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
#20
JOURNAL ARTICLE
Santosh Wadile, Divya Kondgekar, Ashishkumar Moreshwar Banpurkar, Shahena Parveen Raeen, Komal Kulkarni, Snehal Kulkarni
Closure of the large ventricular septal defects (VSD) in infancy can lead to normalization of growth, but data are limited. Our study is done to assess the growth pattern in different age groups of children and lower birth weight babies after shunt closure. This is a prospective observational study that included infants with isolated large VSD operated in infancy. Anthropometric data were collected at baseline and at follow-up, and growth patterns were analyzed. 99 infants were included in the study. The mean age and weight at the time of surgery were 6...
April 18, 2024: Pediatric Cardiology
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