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JOURNAL ARTICLE
Bingzheng Shen, Yating Chen, Yue Wu, Yu Lan, Xiaoqin He, Na Wang, Jun Liu, Yan Yu
BACKGROUND/AIM: With the pharmaceutical innovation and clinical knowledge updating, the continuing education and on-the-job training are extremely important for improving community pharmacists' professional competence. Previous training often adopted traditional lecture-based teaching, and the efficacy was limited. The aim of this study is to develop a new strategy for community pharmacist training. METHODS: Based on the BOPPPS (Bridge-in, Objective, Pre-assessment, Participatory Learning, Post-assessment and Summary) teaching model and workshop method, a continuing on-the-job training program was constructed...
March 15, 2024: BMC Medical Education
#42
JOURNAL ARTICLE
Ivan Berlin, Leontine Goldzahl, Florence Jusot, Noemi Berlin
OBJECTIVES: Maternal smoking during pregnancy is associated with low birth weight (LBW). Reduction of cigarette consumption does not seem to improve birth weight but it is not known whether implementation of periods of smoking abstinence improves it. We assessed whether the number of 7-day periods of smoking abstinence during pregnancy may help reduce the number of newborns with LBW. DESIGN AND SETTING: Secondary analysis of a randomised, controlled, multicentre, smoking cessation trial among pregnant smokers...
March 14, 2024: BMJ Open
#43
JOURNAL ARTICLE
Victor Lopez-Lopez, Christoph Kuemmerli, Javier Maupoey, Rafael López-Andujar, Laura Lladó, Kristel Mils, Philip Müller, Andres Valdivieso, Marina Garcés-Albir, Luis Sabater, Andrea Benedetti Cacciaguerra, Marco Vivarelli, Luis Díez Valladares, Sergio Annese Pérez, Benito Flores, Roberto Brusadin, Asunción López Conesa, Sagrario Martinez Cortijo, Sandra Paterna, Alejando Serrablo, Ferdinand Heinz Walther Toop, Karl Oldhafer, Santiago Sánchez-Cabús, Antonio González Gil, Jose Antonio González Masía, Carmelo Loinaz, Jose Luis Lucena, Patricia Pastor, Cristina Garcia-Zamora, Alicia Calero, Juan Valiente, Antonio Minguillon, Fernando Rotellar, Cándido Alcazar, Javier Aguilo, Jose Cutillas, Jose A Ruiperez-Valiente, Pablo Ramírez, Henrik Petrowsky, Jose Manuel Ramia, Ricardo Robles-Campos
BACKGROUND: Iatrogenic bile duct injury (BDI) during cholecystectomy is associated with a complex and heterogeneous management owing to the burden of morbidity until their definitive treatment. This study aimed to define the textbook outcomes (TOs) after BDI with the purpose to indicate the ideal treatment and to improve it management. METHODS: We collected data from patients with an BDI between 1990 and 2022 from 27 hospitals. TO was defined as a successful conservative treatment of the iatrogenic BDI or only minor complications after BDI or patients in whom the first repair resolves the iatrogenic BDI without complications or with minor complications...
February 21, 2024: Journal of Gastrointestinal Surgery
#44
JOURNAL ARTICLE
Felix Brand, Klaus Stefan Drese
Optoacoustics is a metrology widely used for material characterisation. In this study, a measurement setup for the selective determination of the frequency-resolved phase velocities and attenuations of longitudinal waves over a wide frequency range (3-55 MHz) is presented. The ultrasonic waves in this setup were excited by a pulsed laser within an absorption layer in the thermoelastic regime and directed through a layer of water onto a sample. The acoustic waves were detected using a self-built adaptive interferometer with a photorefractive crystal...
March 1, 2024: Sensors
#45
JOURNAL ARTICLE
Xiao Yang, Yingyi Wu, Xingyu Chen, Jiayue Qiu, Chen Huang
The prognosis of patients with malignant melanoma has been improved in recent decades due to advancements in immunotherapy. However, a considerable proportion of patients are refractory to treatment, particularly at advanced stages. This underscores the necessity of developing a new strategy to improve it. Alternative polyadenylation (APA), as a marker of crucial posttranscriptional regulation, has emerged as a major new type of epigenetic marker involved in tumorigenesis. However, the potential roles of APA in shaping the tumor microenvironment (TME) are largely unexplored...
March 6, 2024: International Journal of Molecular Sciences
#46
JOURNAL ARTICLE
Margarida G Rodrigues, Andreia A Manão, Nuno Tomada, Patrícia M Pascoal
Sexual health is fundamental for overall well-being and quality of life, making it the focus of intervention in Sexual Medicine (SM). Within the National Health Services, Primary Care Physicians (PCPs) guarantee comprehensive care in a biopsychosocial action, including in sexual health. This exploratory study aimed to investigate PCPs' perceptions about their role in SM and how to improve it. A cross-sectional online qualitative design was used, and a sample of 73 Portuguese PCPs was collected. Data was analyzed employing a summative content analysis...
March 13, 2024: International Journal of Impotence Research
#47
JOURNAL ARTICLE
Kiley J McLean, Meghan Haas, Jamie Koenig, Megan Horvath, Mariah Vigil, Nicole E Werner, Lauren Bishop
Research has suggested that autistic adults may have a bigger chance of having mental health and physical health conditions such as depression, anxiety, sleep disorders, diabetes, obesity, and heart problems than adults without autism. Unfortunately, the unique healthcare needs of autistic adults are often overlooked, so it is not clear why autistic adults have worse health or what can be done to improve it. This study wants to find out the challenges autistic adults experience in taking care of their health and in going to different doctors...
March 12, 2024: Autism: the International Journal of Research and Practice
#48
JOURNAL ARTICLE
Rachita Gururaj, Stephen Rajan Samuel, K Vijaya Kumar, Ravishankar Nagaraja, Justin W L Keogh
BACKGROUND: Disrupted circadian rhythm commonly reported in cancer survivors is closely associated with cancer related fatigue, sleep disturbances and compromised quality of life. As more cancer survivors request non-pharmacological treatment strategies for the management of their chronic sleep-related symptoms, there is a need for meta-analyses of various interventions such as exercise on sleep and circadian rhythm disturbances. METHODS: A search for RCT's was conducted in April 2020 and updated in July 2023 using relevant keywords for cancer, sleep, circadian rhythm and exercise interventions on PubMed, Scopus, Web of Science, PEDro and CINAHL...
2024: PeerJ
#49
JOURNAL ARTICLE
Time is ticking for TikTok tics: A retrospective follow-up study in the post-COVID-19 isolation era.
Kinga K Tomczak, Jennifer Worhach, Michael Rich, Olivia Swearingen Ludolph, Susan Eppling, Georgios Sideridis, Tamar C Katz
INTRODUCTION: During the COVID-19 pandemic, an influx of adolescents presented worldwide with acute onset of functional tic-like behaviors (FTLBs). Our goal was to evaluate psychosocial factors around onset, to elucidate outcomes after pandemic isolation protocols were lifted, and to examine therapy and medication management. METHODS: A retrospective review was performed of 56 patients ages 10-18 years with new-onset FTLBs seen at Boston Children's Hospital beginning in March 2020...
March 2024: Brain and Behavior
#50
JOURNAL ARTICLE
Rehema E Lyimo, Yasser H Said, Sokoine L Kivuyo, Deogratias Nkya, Francis F Furia
BACKGROUND: Mortality of children admitted to Intensive Care Units (ICU) is higher in low-to-middle-income countries (LMICs) as compared to high-income countries (HICs). There is paucity of information on outcomes following discharge from ICU, especially from sub-Saharan Africa region. This study was conducted to determine mortality and its associated factors among children admitted to Pediatric ICU (PICU) at Muhimbili National Hospital, from admission to three months after discharge...
March 8, 2024: BMC Pediatrics
#51
JOURNAL ARTICLE
Ivana D Montironi, Sofía Arsaute, Dardo A Roma, María E Cecchini, Agustina Pinotti, Fernando Mañas, Fernando A Bessone, Alejandra de Moreno de LeBlanc, Fabrisio E Alustiza, Romina V Bellingeri, Laura Noelia Cariddi
Early weaning is an important stressor that impairs the piglet´s health, and essential oils appear as promising candidates to improve it instead of antibiotics. The aim of this study was to evaluate the effect of oral supplementation of free and nanoencapsulated Minthostachys verticillata essential oil (EO and NEO, respectively) on immunological, biochemical and antioxidants parameters as well as on gut microbiota in weaned piglets. EO was extracted by hydrodistillation and nanoencapsulation was performed by high-energy method using Tween 80 and Span 60 as surfactants...
March 8, 2024: Veterinary Research Communications
#52
JOURNAL ARTICLE
Yuanyuan Li, Liyuan Song, Yin Cai, Zhijun Fang, Ming Tang
In industry, the task of defect classification and defect localization is an important part of defect detection system. However, existing studies only focus on one task and it is difficult to ensure the accuracy of both tasks. This paper proposes a defect detection system based on improved Yolo_v4, which greatly improves the detection ability of minor defects. For K_Means algorithm clustering prianchors question with strong subjectivity, the paper proposes the Density Based Spatial Clustering of Applications with Noise (DBSCAN) algorithm to determine the number of Anchors...
March 6, 2024: Scientific Reports
#53
JOURNAL ARTICLE
X Y Shi, L L Xu, Y L Gao, Q H Fang, R E Feng, L An
A 64-year-old female patient was admitted to Beijing Chao-Yang Hospital on February 21, 2023 because of right-sided chest pain for more than 4 years and left-sided chest pain for more than 9 months. She had a past medical history of previous tuberculosis and rheumatoid arthritis. A chest CT in October 2018 revealed multiple pulmonary nodules. A CT-guided biopsy showed no tumors, and adenosine deaminase levels in the pleural effusion were elevated, suggesting a high likelihood of tuberculosis. As a result, anti-tuberculosis treatment was initiated in March 2019...
March 12, 2024: Chinese Journal of Tuberculosis and Respiratory Diseases
#54
JOURNAL ARTICLE
Bilal Bashir, See Kwok, Anthony S Wierzbicki, Alan Jones, Charlotte Dawson, Paul Downie, Fiona Jenkinson, Hannah Delaney, Michael Mansfield, Dev Datta, Yee Teoh, Paul Hamilton, Natalie Forrester, Dawn O'Sullivan, Maryam Ferdousi, Paul N Durrington, Alaa AbdelRazik, Antonio Gallo, Philippe Moulin, Handrean Soran
BACKGROUND AND AIMS: Prognosis and management differ between familial chylomicronaemia syndrome (FCS), a rare autosomal recessive disorder, and multifactorial chylomicronaemia syndrome (MCS) or severe mixed hyperlipidaemia. A clinical scoring tool to differentiate these conditions has been devised but not been validated in other populations. The objective of this study was to validate this score in the UK population and identify any additional factors that might improve it. METHODS: A retrospective validation study was conducted using data from 151 patients comprising 75 FCS and 76 MCS patients...
February 10, 2024: Atherosclerosis
#55
JOURNAL ARTICLE
Rosa María Cárdaba-García, Raúl Soto-Cámara, Noemi García-Santa-Basilia, María Paz Matellán-Hernández, Henar Onrubia-Baticón, Carmen María Martínez-Caballero, Israel John Thuissard-Vasallo, Susana Navalpotro-Pascual
OBJECTIVE: To analyse the influence of the COVID-19 pandemic and the perception of self-efficacy on the health professionals of the Spanish out-of-hospital emergency services. DESIGN: Observational, cross-sectional and descriptive with a survey methodology of 1710 participants from Spain (1 February-30 April, 2021). METHODS: The mental health of healthcare workers was assesed in terms of stress, anxiety and depression, as well as their self-efficacy...
March 5, 2024: Journal of Advanced Nursing
#56
JOURNAL ARTICLE
Ziyang Chang, Dingqiang Liang, Shirong Sun, Shuo Zheng, Kexin Sun, Haiping Wang, Yanguang Chen, Daliang Guo, Huifang Zhao, Lizheng Sha, Wenyan Jiang
Cellulosic paper-based electrode materials have attracted increasing attention in the field of flexible supercapacitor. As a conductive polymer, polyaniline exhibits high theoretical pseudocapacitive capacitance and has been applied in paper-based electrode materials along with cellulose fibers. However, the stacking of polyaniline usually leads to poor performance of electrodes. In this study, metal-organic coordination polymers of zirconium-alizarin red S and zirconium-phytic acid are applied to modulate the polyaniline layer to obtain high-performance cellulosic paper-based electrode materials...
March 3, 2024: International Journal of Biological Macromolecules
#57
JOURNAL ARTICLE
Zs Soósné Kiss, J Vitrai, J Takács, J Á Lukács, A Falus, H J Feith
BACKGROUND: Although it is widely recognized that more attention needs to be paid to children's fluid intake, there is little information on how to improve it. Peer education has been suggested as an effective approach to changing health behaviors among school children. As a new approach, our study piloted a peer education program to improve children's fluid intake in primary schools. METHODS: University students were prepared for their role as peer educators in an elective university course, including the concept of peer education and different pedagogical methods...
March 15, 2024: Heliyon
#58
JOURNAL ARTICLE
Xin Zhang, Le Gao, Zhimin Wang, Yong Yu, Yudong Zhang, Jin Hong
Alzheimer's disease(AD) poses a significant challenge due to its widespread prevalence and the lack of effective treatments, highlighting the urgent need for early detection. This research introduces an enhanced neural network, named ADnet, which is based on the VGG16 model, to detect Alzheimer's disease using two-dimensional MRI slices. ADNet incorporates several key improvements: it replaces traditional convolution with depthwise separable convolution to reduce model parameters, replaces the ReLU activation function with ELU to address potential issues with exploding gradients, and integrates the SE(Squeeze-and-Excitation) module to enhance feature extraction efficiency...
February 29, 2024: Heliyon
#59
JOURNAL ARTICLE
Vira V Navrotska, Oksana P Horpyniuk, Halyna D Boreiko
OBJECTIVE: Aim: To determine the problematic issues of ensuring the rights and freedoms of persons suffering from mental disorders and to whom CMM are applied in criminal proceedings under the legislation of Ukraine and the legislation of the states that adhere to the modern concepts of international standards of human rights ensuring to a person the CMM are applied to. PATIENTS AND METHODS: Materials and Methods: Legal positions of the ECHR, criminal procedural legislation of a number of states, and a survey of scientists and practitioners conducted by the authors are used in this paper (total number of respondents was 168)...
2024: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
#60
REVIEW
Abdul W Kazi, Erika J Yoo, David Oxman
Trust is an essential element in the relationship between patients and intensive care unit (ICU) clinicians. Without a foundation of trust, communication is difficult, conflict is more likely, and even clinical outcomes can be affected. The ICU is a particularly challenging environment for trust to flourish. Illness occurs suddenly, emotions can be charged, the environment is impersonal, and there is rarely a prior relationship between patients and their caregivers. Therefore, intensivists must have some understanding of the factors that impact patient and family trust, as well as the actions they can take to improve it...
February 28, 2024: Journal of Critical Care
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