Dominique Vervoort, Grace S Lee, Hillary Lia, Abdul Muqtader Afzal, Derrick Y Tam, Maral Ouzounian, Johanna J M Takkenberg, Harindra C Wijeysundera, Stephen E Fremes
OBJECTIVES: Randomized controlled trials are the gold standard for evidence generation in medicine but are limited by their real-world generalizability, resource needs, shorter follow-up durations, and inability to be conducted for all clinical questions. Decision analysis models may simulate trials and observational studies by using existing data and evidence- and expert-informed assumptions, and extend analyses over longer time horizons, different study populations, and specific scenarios, helping to translate population outcomes to patient-specific clinical and economic outcomes...
March 27, 2024: European Journal of Cardio-thoracic Surgery