keyword
https://read.qxmd.com/read/38524379/the-relationship-between-artificial-intelligence-assisted-oct-angiography-derived-foveal-avascular-zone-parameters-and-visual-field-defect-progression-in-eyes-with-open-angle-glaucoma
#1
JOURNAL ARTICLE
Takahiro Ninomiya, Naoki Kiyota, Parmanand Sharma, Kazuko Omodaka, Noriko Himori, Masayuki Yasuda, Hiroshi Kunikata, Toru Nakazawa
PURPOSE: To investigate clinical factors associated with foveal avascular zone (FAZ) parameters obtained using OCT angiography (OCTA) with assistance from a previously developed artificial intelligence (AI) platform in eyes with open-angle glaucoma (OAG). DESIGN: Retrospective longitudinal. PARTICIPANTS: This study followed up 885 eyes of 558 patients with OAG for ≥ 2 years; all eyes underwent ≥ 5 Humphrey visual-field (VF) tests and had 3...
2024: Ophthalmol Sci
https://read.qxmd.com/read/38519434/clinical-correlates-of-respiratory-disorders-in-patients-with-severe-multiple-sclerosis-a-cross-sectional-cohort
#2
JOURNAL ARTICLE
Elisabeth Maillart, Stefania Redolfi, Céline Louapre, Marion Houot, Emeline Chaugne, Pierantonio Laveneziana, Aurelian Ungureanu, Bruno Stankoff, Isabelle Arnulf, Caroline Papeix, Benedetta Bodini, Thomas Similowski, Catherine Lubetzki, Capucine Morélot-Panzini
BACKGROUND: Respiratory disorders remain incompletely described in multiple sclerosis (MS), even though they are a frequent cause of death. METHODS: The objective was to describe respiratory disorders in MS patients with Expanded Disability Status Score (EDSS) ⩾ 6.5. Diaphragm dysfunction was defined by at least two of the seven criteria: clinical signs, inspiratory recruitment of neck muscles during wakefulness, reduced upright vital capacity (VC) < 80%, upright-to-supine VC ⩾ 15% of upright VC, decrease in Maximal Inspiratory Pressure < 60%, phasic activation of inspiratory neck muscles during sleep, and opposition of thoracic and abdominal movements during sleep...
March 22, 2024: Multiple Sclerosis: Clinical and Laboratory Research
https://read.qxmd.com/read/38513627/sleep-disorders-and-sleep-disturbances-in-persons-with-multiple-sclerosis-a-population-based-matched-case-control-study-in-denmark
#3
JOURNAL ARTICLE
Elisabeth Framke, Poul Jørgen Jennum, Lau Caspar Thygesen, Melinda Magyari
Introduction Adverse sleep is common in multiple sclerosis (MS). Population-based studies including adequate control groups are lacking. We hypothesized that the prevalence of sleep disorders and other sleep disturbances would be higher in persons with MS than in controls. Methods We conducted a population-based study linking individual-level data from the Danish MS Registry (n=21,943 persons with MS) and the Danish Population Registry (n=109,715 matched controls) with information on sleep disorders from the Danish National Patient Registry and other sleep disturbances assessed by dispensed prescription drugs from the Danish National Prescription Registry...
March 21, 2024: Neuroepidemiology
https://read.qxmd.com/read/38511236/a-quality-improvement-initiative-to-increase-skin-to-skin-care-duration-in-preterm-neonates
#4
JOURNAL ARTICLE
Palanikumar Balasundaram, Melissa Frascone, Samantha Wnukowski, Alana G Murphy, Jillian Connors
BACKGROUND: Skin-to-skin (STS) care effectively improves neonatal outcomes, particularly for preterm neonates. However, utilization of STS remains suboptimal for the most vulnerable preterm neonates in the first 4 weeks of life. This quality improvement (QI) project aimed to increase STS duration for neonates under 35 weeks gestation. METHODS: The QI initiative was conducted in a 35-bed level IV NICU within a teaching hospital in New York City from July 2021 to January 2023...
April 1, 2024: Hospital Pediatrics
https://read.qxmd.com/read/38459862/-paraneoplastic-anti-n-methyl-d-aspartate-receptor-encephalitis-associated-with-anterior-mediastinal-mature-teratoma
#5
JOURNAL ARTICLE
Tatsuya Katayama, Jun Amioka, Yoshinori Handa
We report a 27 years-old previously healthy male admitted to a psychiatric hospital because of abnormal behavior. He was suspected meningoencephalitis with fever, abnormal sweating, muscle tone, confusion, and introduced to the neurology department of our hospital. After admission, increasing convulsions and apnea attack required mechanical ventilation therapy. Anti-N-methyl-D-aspartate( NMDA) - receptor encephalitis was diagnosed based on positive (20-fold) anti-NMDA antibody in cerebrospinal fluid examination...
February 2024: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://read.qxmd.com/read/38451037/defining-the-shape-of-the-mylohyoid-muscle-a-morphometric-imaging-study
#6
JOURNAL ARTICLE
Linda C Magaña, Barton F Branstetter, Ryan J Soose
OBJECTIVES: Implantable hypoglossal nerve stimulation (HNS) therapy is an evolving therapeutic alternative for patients with refractory obstructive sleep apnea (OSA). The muscular anatomy of this region has implications for surgical access through this zone as well as positioning and anchoring of hardware in this area. The purpose of this study was to radiologically describe the topography of the mylohyoid muscle and adjacent structures across a wide age spectrum. METHODS: We retrospectively evaluated computed tomography scans of the neck in 102 patients who were imaged for reasons unrelated to the floor of mouth or submental space...
March 7, 2024: Laryngoscope
https://read.qxmd.com/read/38450516/case-report-of-hypoglossal-nerve-stimulation-therapy-failure-due-to-significant-underlying-central-sleep-apnea
#7
Dhruba Banerjee, Chang-Hoon Lee, Kyoungbin Im
Hypoglossal nerve stimulation (HNS) is indicated for obstructive sleep apnea (OSA) but is ineffective in treating central sleep apnea (CSA). We describe two patients implanted with HNS after being diagnosed with OSA at outside sleep labs and failing a trial of continuous positive airway pressure (CPAP) therapy. Despite successful HNS implantation, the patients continued to have persistent symptoms with residual apnea-hypopnea indices above 25 events/h. Although OSA was the presenting diagnosis, we discovered a significant CSA component in the original diagnostic sleep data upon careful review...
March 7, 2024: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://read.qxmd.com/read/38450501/an-adolescent-with-wolfram-syndrome-and-central-sleep-apnea
#8
Jamie C Harris, Jay D Kenkare, Craig M Schramm
Wolfram syndrome (WS) is a rare autosomal recessive disorder affecting approximately 1:500,000 individuals. The disorder is most commonly caused by mutations in the WFS1 gene, which encodes an endoplasmic reticulum (ER) protein, wolframin, which is thought to protect against ER stress-related apoptosis. The major clinical findings of WS are diabetes mellitus and optic atrophy, both of which usually appear before 16 years of age. Common additional findings include sensorineural hearing impairment, central diabetes insipidus, non-autoimmune hypothyroidism, delayed puberty, neurogenic bladder, cerebellar ataxia, and psychiatric disorders...
March 7, 2024: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://read.qxmd.com/read/38444051/apneic-response-to-fentanyl-in-adult-rats-role-of-laryngeal-afferents
#9
JOURNAL ARTICLE
Jianguo Zhuang, Xiuping Gao, Shan Shi, Fadi Xu
Intravenous (systemic) bolus injection of fentanyl (FNT) reportedly induces an immediate vagal-mediated apnea; however, the precise origin of vagal afferents responsible for this apnea remains unknown. We tested whether intralaryngeal (local) application of FNT would also trigger an apnea and whether the apneic response to both local and systemic administration of FNT was laryngeal afferent-mediated. Cardiorespiratory responses to FNT were recorded in anesthetized male adult rats with and without bilateral sectioning of the superior laryngeal nerve (SLNx) or peri-SLN capsaicin treatment (SLNcap) to block local C-fiber signal conduction...
March 2024: Physiological Reports
https://read.qxmd.com/read/38440255/prevalence-of-central-sleep-apnea-among-veterans-and-response-rate-to-continuous-positive-airway-pressure-therapy
#10
JOURNAL ARTICLE
Nesrine Adly Ibrahim, Abdulghani Sankari, Ahmad Aldwaikat, Nishtha Pandya, Susmita Chowdhuri, Anan Salloum, Jennifer L Martin, Salam Zeineddine, M Safwan Badr
STUDY OBJECTIVES: Sleep-disordered breathing (SDB) is common in the Veteran population. In this retrospective study, we investigated the prevalence of comorbid central and obstructive SDB and the response rate to PAP among Veterans. METHODS: Veterans were screened from a single VA medical center who had polysomnography (PSG) study from 2017 to 2021 to ascertain the presence, severity, and type of SDB by measuring the apnea-hypopnea index (AHI) and central apnea index (CAI)...
2024: Sleep advances: a journal of the Sleep Research Society
https://read.qxmd.com/read/38438337/associations-of-50-modifiable-risk-factors-with-atrial-fibrillation-using-mendelian-randomization-analysis
#11
JOURNAL ARTICLE
Zhuxin Zhang, Le Li, Zhenhao Zhang, Zhao Hu, Yulong Xiong, Likun Zhou, Yan Yao
BACKGROUND: Substantial focus has been placed on atrial fibrillation (AF) treatment and associated stroke prevention rather than preventing AF itself. We employed Mendelian randomization (MR) approach to examine the causal relationships between 50 modifiable risk factors (RFs) and AF. METHODS: Instrumental variables for genetically predicted exposures were derived from corresponding genome-wide association studies (GWASs). Summary-level statistical data for AF were obtained from a GWAS meta-analysis (discovery dataset, N = 1,030,836) and FinnGen (validation dataset, N = 208,594)...
March 4, 2024: European Journal of Clinical Investigation
https://read.qxmd.com/read/38433693/-the-relationship-between-birth-weight-and-obstructive-sleep-apnea-in-children
#12
JOURNAL ARTICLE
Zhe Deng, Guixiang Wang, Yuwei Hou, Yujie Liu, Yanxia Xu, Ying Xu, Dongjie Seng, Fugen Han, Jing Zhao
Objective: To study the relationship between children's birth weight and obstructive sleep apnea(OSA). Methods: The sleep data and birth information of children who underwent polysomnography in the Department of Otorhinolaryngology-Head and Neck Surgery of Henan Children's Hospital from October 2020 to July 2022 were retrospectively analyzed. The data of OSA detection rate, OSA severity, sleep structure and respiratory parameters in different birth weight groups were analyzed. Results: A total of 2 778 children met the inclusion criteria, including 1 833 males and 945 females...
March 2024: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://read.qxmd.com/read/38432888/clinical-characteristics-of-bronchopulmonary-dysplasia-in-very-preterm-infants
#13
JOURNAL ARTICLE
Yonghui Yang, Xiaori He, Xuefei Zhang, Pingyang Chen
OBJECTIVES: With the development of perinatal and neonatal intensive care medicine, the survival rate of very premature infants increases year by year. However, the incidence of bronchopulmonary dysplasia (BPD) increases year by year, which seriously affects the survival prognosis of very premature infants. How to prevent and treat BPD effectively has become the focus of neonatologists. This study aims to provide ideas for the prevention and treatment of BPD in very preterm infants via analyzing the clinical characteristics of BPD...
October 28, 2023: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://read.qxmd.com/read/38420961/prevalences-of-sleep-related-breathing-disorders-and-severity-factors-in-chronic-spinal-cord-injury-and-abled-bodied-individuals-undergoing-rehabilitation-a-comparative-study
#14
JOURNAL ARTICLE
Patrícia Souza Bastos, Tatiana Leal Dutra Amaral, Hani Camille Yehia, Almir Tavares
STUDY OBJECTIVES: The objective of this study is to discern distinguishing characteristics of sleep-related breathing disorders (SRBD) in individuals with chronic spinal cord injury (CSCI) compared to able-bodied participants (non-CSCI). Additionally, the study investigates factors associated with SRBD severity. METHODS: This is a cross-sectional analysis of 123 able-bodied individuals, 40 tetraplegics, and 48 paraplegics, who underwent attended or partially supervised full polysomnography, for suspected SRBD, in a rehabilitation center...
February 29, 2024: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://read.qxmd.com/read/38417306/type-one-chiari-malformation-as-a-cause-of-central-sleep-apnea-and-hypoventilation-in-children
#15
JOURNAL ARTICLE
Turkka Kirjavainen, Päriä Miraftabi, Laura Martelius, Atte Karppinen
OBJECTIVES: Chiari type 1 malformation (CM1) may occasionally lead to central sleep apnea (CSA). We studied, in a large clinical cohort of pediatric CM1 patients, the effect of CM1 on breathing during sleep. METHODS: This is a retrospective single pediatric pulmonology center study with a systematic evaluation of pediatric CM1 patients under age 18 with polysomnography (PSG) during 2008-2020. Children with syndromes were excluded. All patients had undergone head and spine magnetic resonance imaging...
February 16, 2024: Sleep Medicine
https://read.qxmd.com/read/38410942/association-of-sex-with-cardiovascular-outcomes-in-heart-failure-patients-with-obstructive-or-central-sleep-apnea
#16
JOURNAL ARTICLE
Boping Huang, Yan Huang, Mei Zhai, Qiong Zhou, Shiming Ji, Huihui Liu, Xiaofeng Zhuang, Yuhui Zhang, Jian Zhang
BACKGROUND: This study investigated the association of sex with cardiovascular outcomes in a prospective cohort of patients with heart failure (HF) with obstructive sleep apnea or central sleep apnea. METHODS AND RESULTS: Patients were screened for sleep apnea on admission using multichannel cardiopulmonary monitoring from May 2015 to July 2018. The primary outcome was a composite of cardiovascular death or unplanned hospitalization for worsening HF. Ultimately, 453 patients with HF with obstructive sleep apnea or central sleep apnea were included; 71 (15...
February 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38400804/ictal-central-apnea-is-predictive-of-mesial-temporal-seizure-onset-an-intracranial-investigation
#17
JOURNAL ARTICLE
Nuria Lacuey, Blanca Talavera, Oman Magana-Tellez, Oscar Mancera-Páez, Norma Hupp, Xi Luo, Johnson P Hampson, Jaison Hampson, M R Sandhya Rani, Manuela Ochoa-Urrea, Omar A Alamoudi, Stephen Melius, Sandipan Pati, Jay Gavvala, Nitin Tandon, John C Mosher, Samden D Lhatoo
OBJECTIVE: Ictal central apnea (ICA) is a semiological sign of focal epilepsy, associated with temporal and frontal lobe seizures. In this study, using qualitative and quantitative approaches, we aimed to assess the localizational value of ICA. We also aimed to compare ICA clinical utility in relation to other seizure semiological features of focal epilepsy. METHODS: We analyzed seizures in patients with medically refractory focal epilepsy undergoing intracranial stereotactic electroencephalographic (SEEG) evaluations with simultaneous multimodal cardiorespiratory monitoring...
February 24, 2024: Annals of Neurology
https://read.qxmd.com/read/38398299/influence-of-obstructive-apnea-index-on-persistent-left-ventricular-dysfunction-in-patients-with-st-segment-elevation-myocardial-infarction
#18
JOURNAL ARTICLE
Jin Kirigaya, Noriaki Iwahashi, Tomoaki Ishigami, Takeru Abe, Masaomi Gohbara, Yohei Hanajima, Mutsuo Horii, Kozo Okada, Yasushi Matsuzawa, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi
Background : We retrospectively investigated the effects of the severity and classification of sleep-disordered breathing (SDB) on left ventricular (LV) function in patients with ST-segment elevation myocardial infarction (STEMI). Methods : A total of 115 patients with STEMIs underwent a sleep study using a multichannel frontopolar electroencephalography recording device (Sleep Profiler) one week after STEMI onset. We evaluated LV global longitudinal strain (LV-GLS) using two-dimensional echocardiography at one week and seven months...
February 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38379992/a-polysomnographic-study-of-slow-wave-sleep-loss-in-elderly-patients-with-epilepsy
#19
JOURNAL ARTICLE
Sihang Wang, Meina Wu, Sangru Wu, Fang Lin, Xiaolin Ji, Jinzhu Yan
OBJECTIVE: The primary objective is to explore what causes slow-wave sleep loss in elderly patients with epilepsy. The secondary objective is to identify the PSG characteristics in elderly patients with epilepsy. The clinical demographics, sleep architecture, sleep-related events, and interictal epileptiform discharges are to be evaluated in the objectives. METHODS: The video electroencephalography (VEEG) and polysomnogram (PSG) data from 44 elderly patients with epilepsy and 52 elderly patients with sleep disorders but without definite central nervous system diseases were analysed...
February 29, 2024: Heliyon
https://read.qxmd.com/read/38370439/obstructive-sleep-apnea-nocturnal-hypoxemia-and-retinal-microvasculature-the-atherosclerosis-risk-in-communities-study
#20
JOURNAL ARTICLE
Nathan Hoeft, Kelsie M Full, Jeffrey R Misialek, Kamakshi Lakshminarayan, Srishti Shrestha, Jennifer A Deal, Pamela L Lutsey
STUDY OBJECTIVES: Retinal microvascular pathology (RMP) and obstructive sleep apnea (OSA) are both cardiovascular disease risk factors. Limited data exists on their interrelationship. We tested the hypotheses that OSA and nocturnal hypoxemia would be associated with RMP and vessel calibers. METHODS: We conducted a quasi-cross-sectional analysis of 1625 participants in the Atherosclerosis Risk in Communities Sleep Heart Health Study. Participants completed in-home polysomnography monitoring (1996-1998) and were categorized by OSA severity (apnea-hypopnea index: <5, 5-14...
2024: Sleep advances: a journal of the Sleep Research Society
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