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pumpkin seeds

Anan O Alhawiti, Fawzia H Toulah, Majed H Wakid
OBJECTIVE: The main drug used against Hymenolepis nana is praziquantel (PZQ), which causes side effects and toxicity. In contrast, natural extracts have limited side effects and are safer. Past researches have proved that pumpkin seeds are effective as natural antimicrobial and antiparasitic treatment. The present study investigates a natural alternative and less expensive treatment against H. nana using pumpkin seeds. MATERIALS AND METHODS: Healthy female albino mice were divided into four groups: normal control, infected control with H...
February 18, 2019: Acta Parasitologica
Cheryl Lans
ETHNOPHARMACOLOGICAL RELEVANCE: There are insufficient safe and effective treatments for chronic pain in pets. In cases such as osteoarthritis there is no commercially available cure and veterinarians use NSAIDs to manage pain. Pet owners may have to plan for a lifetime of plant-based treatment for the conditions that lead to chronic pain in pets. Phytopharmacotherapies have the advantage of being less toxic, cheap or free, readily available, are more likely to be safe for long-term use and have the potential to reset the immune system to normal functioning...
February 14, 2019: Journal of Ethnopharmacology
Nilutpal Sharma Bora, Bhaskar Mazumder, Santa Mandal, Yangchen D Bhutia, Sanghita Das, Sanjeev Karmakar, Pronobesh Chattopadhyay, Sanjai K Dwivedi
OBJECTIVE: Melatonin and pumpkin seed oil, along with US FDA approved UV filters were incorporated into a formulation for enhancement of UV protection by exerting an antioxidant effect. The objective of this study was to assess the protective effect of this formulation against ultraviolet (UV) radiation-induced photo dermatitis in rats, which is an established model to study the aetiopathogenic mechanisms in psoriasis vulgaris, as the former exhibits the same features to those of clinical psoriasis vulgaris in humans...
February 11, 2019: Immunopharmacology and Immunotoxicology
Beni Lestari, Ziana Walidah, Rohmad Yudi Utomo, Retno Murwanti, Edy Meiyanto
No abstract text is available yet for this article.
January 20, 2019: Phytotherapy Research: PTR
Beatriz de Lamo, Manuel Gómez
The use of oilseeds in bakery products has gained popularity in recent years, both for their organoleptic and nutritional characteristics. The aim of this work is to provide an overview of the studies centered on the use of oilseeds (flaxseed, chia, sunflower, pumpkin, sesame and poppyseed) in breads and other bakery products. This review highlights the effect of oilseeds on the mechanical and physical properties of bread according to the enrichment level, origin and way of addition (whole, crushed, oil or mucilage)...
November 20, 2018: Foods (Basel, Switzerland)
Subiah H Arzoo, Krishna Chattopadhyay, Saheli Banerjee, Brajadulal Chattopadhyay
OBJECTIVE: Diabetes mellitus occurs due to either deficiency of insulin or resistance to insulin. Synthetic drugs and insulin therapy against diabetes possess numerous drawbacks. Diabetic people are advised to choose low-glycemic food and herbal products to control diabetes. This study aims to examine the synergistic effects of aqueous root Salep ofGymnadenia orchidis Lindl and pumpkin seed powder on Streptozotocin induced diabetic mice. METHODS: Out of 6 groups, animals in 2 groups were kept as control and rest 4 groups were made diabetic by Streptozotocin...
November 10, 2018: Diabetes Research and Clinical Practice
Valquíria Maeda Rojas, Luis Felipe da Costa Baptista Marconi, Alexandre Guimarães-Inácio, Fernanda Vitória Leimann, Augusto Tanamati, Ângela Maria Gozzo, Renata Hernandez Barros Fuchs, Maria Filomena Barreiro, Lillian Barros, Isabel C F R Ferreira, Ailey Aparecida Coelho Tanamati, Odinei Hess Gonçalves
There is an increasing demand for healthier foodstuff containing specific compounds such as Polyunsaturated Fatty Acids (PUFAs). In the case of PUFAs, protection against oxidative degradation is challengeable and microencapsulation emerges as an alternative. Mayonnaises containing microencapsulated oils could be a source of PUFAs. The objective was to formulate mayonnaises containing microencapsulated chia seeds oil, pumpkin seeds oil or baru oil. Micrometric particles with high encapsulation efficiency were produced and thermal analyses indicated an increased thermal stability of all oils after encapsulation...
February 15, 2019: Food Chemistry
Sayed A Tantawy, Hany Mi Elgohary, Dalia M Kamel
Background: A significant number of men who are younger than 50 years visit urologists for interminable prostatitis. This study aimed to thoroughly investigate the effect of pumpkin seed oil (PSO) phonophoresis on chronic nonbacterial prostatitis (CNBP). Subjects and methods: Sixty patients with CNBP were randomly assigned to three groups: Group A, wherein patients were treated with PSO using phonophoresis; Group B, where patients underwent transperineal continuous low-intensity ultrasound (LIUS); and Group C, wherein patients underwent placebo LIUS...
2018: Research and Reports in Urology
K Yogeswara Chari, Picheswara Rao Polu, Rekha R Shenoy
Background: Cancer is one of the most important public health burdens in developed and developing countries. Colon cancer (CC) is the sixth most common cause of death in India and third most important cause in developed countries. For treating cancer, several synthetic agents are available but they cause side effects. Therefore, there is a need to investigate plant derived anticancer agents with lesser side effects. In this direction, we have made an attempt to unravel the potential of pumpkin seed extract for treating colon cancer...
2018: Journal of Toxicology
Linda H Münger, Samy Boulos, Laura Nyström
Dietary plant foods are characterized by a vast molecular diversity of glycosylated sterols (SG) that differ in the structure of the steryl backbone. The identification of these polar steryl conjugates represents a major challenge as they are structurally highly similar, and commercial standards are limited to a few naturally abundant species. Spectral databases do not yet contain MS/MS spectra of these sterol conjugates obtained by electrospray ionization (ESI), which would facilitate their reliable identification...
2018: Frontiers in Chemistry
Eissa I Fawzy, Aida I El Makawy, M Mahmoud El-Bamby, H Osama Elhamalawy
The present study was conducted to evaluate the ameliorative role of pumpkin seed oil (PSO) against potential adverse effects of bisphenol-A (BPA) in male mice. BPA was administered to the mice orally at a dose of 50 mg/kg body weight once a day for 28 successive days. While, PSO was administered to the mice orally at 1 mL/kg b w either before, with or after treatment of BPA, once a day for 28 successive days. The studied parameters were DNA damage evaluation using comet assay in liver and testes cells and micronucleus test in bone marrow; and histopathological examination of liver and testes tissues...
2018: Toxicology Reports
X Zhang, M Babadoost
This study was conducted to determine characteristics of Xanthomonas cucurbitae, the causal agent of bacterial spot of pumpkin, and survival of the bacterium in pumpkin seeds. Fourteen X. cucurbitae isolates from the north central region of the United States, along with the X. cucurbitae strain 23378 from the American Type Culture Collection, were included in this study. The range of minimum, optimum, and maximum temperatures for colony development of X. cucurbitae were 4 to 6°C, 24 to 30°C, and 34 to 36°C, respectively...
September 2018: Plant Disease
Olamiposi Olajumoke Omosowone, Abibat Motunrayo Ogunrinde
The study evaluated the effect of partial or total supplementation of soybean meal with full-fat Telifaria occidentalis seed meal on performance and whole body composition of Heteroclarias fingerlings. Five iso-nitrogenous (40% crude protein) basal diets were prepared using locally available feedstuffs, while T. occidentalis seed meal was added at varying inclusion levels (0%, 25%, 50%, 75% and 100%). One hundred and fifty apparently healthy Heteroclarias fingerlings (4.26 ± 0.26 g) were stocked in glass tanks (50 L capacity) at 10 fish / tank with each treatment in triplicate...
July 2018: Food Science & Nutrition
Flávia G Cândido, Fernanda C E de Oliveira, Mário Flávio C Lima, Carina A Pinto, Letícia L da Silva, Hércia S D Martino, Marcelo H Dos Santos, Rita de Cássia G Alfenas
We investigated if pumpkin and flaxseeds could improve postprandial glycemic, food intake, and appetitive responses. Herein, we hypothesize based on the literature that pumpkin seed has potential to lower postprandial glycemic effects. Therefore, we conducted a randomized, single-blind, placebo-controlled, crossover design study involving normoglycemic adults (food intake: n = 25; glycemia: n = 15). Three high-carbohydrate mixed meals presenting no seed (control [C]) or 65 g of the tested seeds (pumpkin seed [P] or flaxseed [F]) were consumed in 3 nonconsecutive days...
August 2018: Nutrition Research
Karin Endo, Taeko Mizutani, Yuri Okano, Hitoshi Masaki
BACKGROUND: The induction of skin pigmentation by ultraviolet (UV) radiation has been shown to result from factors secreted from UV-exposed keratinocytes that enhance melanogenesis in melanosomes (MSs) and stimulates their transfer to keratinocytes. Among those factors, it has been reported that α-melanocyte stimulating hormone, which is converted from the precursor proopiomelanocortin (POMC) following UV exposure, stimulates the transfer of MSs from melanocytes to surrounding keratinocytes...
July 25, 2018: Journal of Cosmetic Dermatology
José Francisco Díaz Nájera, Jaime Sahagún Castellanos, Mateo Vargas Hernández, Sergio Ayvar Serna, Omar Guadalupe Alvarado Gómez, Clemente Villanueva Verduzco, Marcelo Acosta Ramos
Fruit rot is the principal phytopathological problem of pipiana pumpkin ( Cucurbita argyrosperma Huber) in the state of Guerrero. The aims of this research were to 1) identify the causal agent of southern blight on pumpkin fruits by morphological, pathogenic, and molecular analysis (ITS1, 5.8S, ITS2); 2) evaluate in vitro Trichoderma spp. strains and chemical fungicides; and 3) evaluate under rainfed field conditions, the strains that obtained the best results in vitro , combined with fungicides during two crop cycles...
June 2018: Plant Pathology Journal
Libo Wang, Long Cheng, Fangcheng Liu, Tengfei Li, Zeyuan Yu, Yaqin Xu, Yu Yang
In the present study, ultrasound-assisted extraction (UAE) of crude polysaccharides (PSP) from pumpkin seeds was optimized by response surface method (RSM). The polysaccharide yield (2.29 ± 0.14%), which agreed closely with the theoretical predicted value 2.40%, was obtained under the optimal extraction conditions: extraction time 24 min, extraction temperature 50 °C, ultrasonic power 347 W, and liquid to solid ratio 23 mL/g. After further purification by two-step column chromatography, a novel polysaccharide (PSP-1) was isolated from pumpkin seeds...
May 18, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Gabriela M Chiocchetti, Elisabete A De Nadai Fernandes, Anna A Wawer, Susan Fairweather-Tait, Tatiana Christides
Background : Iron deficiency is a public health problem in many low- and middle-income countries. Introduction of agro-industrial food by-products, as additional source of nutrients, could help alleviate this micronutrient deficiency, provide alternative sources of nutrients and calories in developed countries, and be a partial solution for disposal of agro-industry by-products. Methods : The aim of this study was to determine iron bioavailability of 5 by-products from Brazilian agro-industry (peels from cucumber, pumpkin, and jackfruit, cupuaçu seed peel, and rice bran), using the in vitro digestion/ Caco-2 cell model; with Caco-2 cell ferritin formation as a surrogate marker of iron bioavailability...
May 16, 2018: Medicines (Basel, Switzerland)
Alexander Michael Greiling, Christiane Schwarz, Martin Gierus, Markus Rodehutscord
The objectives of this study were to investigate the digestibility of pumpkin seed cake (PSC) for the rainbow trout, Oncorhynchus mykiss (Walbaum, 1792), and effects on performance and product quality traits of four different fish species when PSC partially replaced fishmeal in extruded diets. A digestibility trial was carried out to determine apparent digestibility coefficients (ADC) for crude protein (CP), ether extract (EE) and gross energy (GE) of PSC fed to rainbow trout. In subsequent growth trials, effects on performance and morphological traits and fillet colour values of four different fish species [rainbow trout; brook trout, Salvelinus fontinalis (Mitchill, 1814); African sharptooth catfish, Clarias gariepinus (Burchell, 1822); and wels catfish, Silurus glanis (Linnaeus, 1758)] were evaluated when 60% of fishmeal protein of a reference diet was replaced by PSC protein (based on digestible CP)...
June 2018: Archives of Animal Nutrition
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