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JOURNAL ARTICLE
Avner Reshef, Thomas Buttgereit, Stephen D Betschel, Teresa Caballero, Henriette Farkas, Anete S Grumach, Michihiro Hide, Ankur K Jindal, Hilary Longhurst, Jonathan Peter, Marc A Riedl, Yuxiang Zhi, Werner Aberer, Mohamed Abuzakouk, Tariq Al Farsi, Nashat Al Sukaiti, Mona Al-Ahmad, Sabine Altrichter, Emel Aygören-Pürsün, Maria Luisa Baeza, Noemi Anna Bara, Andrea Bauer, Jonathan A Bernstein, Isabelle Boccon-Gibod, Hanna Bonnekoh, Laurence Bouillet, Zenon Brzoza, Anette Bygum, Oscar Calderon, Regis de Albuquerque Campos, Freya Helena Campos Romero, Mauro Cancian, Herberto Jose Chong-Neto, George Christoff, Stefan Cimbollek, Danny M Cohn, Timothy Craig, Inna Danilycheva, Razvigor Darlenski, Aurélie Du-Thanh, Luis Felipe Ensina, Daria Fomina, Luz Fonacier, Atsushi Fukunaga, Asli Gelincik, Pedro Giavina-Bianchi, Kiran Godse, Mark Gompels, Margarida Goncalo, Maia Gotua, Guillermo Guidos-Fogelbach, Mar Guilarte, Alicja Kasperska-Zajac, Constance H Katelaris, Tamar Kinaciyan, Pavel Kolkhir, Kanokvalai Kulthanan, Marcin Kurowski, Elena Latysheva, Antti Lauerma, David Launay, Ramon Lleonhart, William Lumry, Alejandro Malbran, Ramzy Mohammed Ali, Iman Nasr, Sandra Nieto-Martinez, Claudio Parisi, Ruby Pawankar, Macarena Piñero-Saavedra, Todor A Popov, Grzegorz Porebski, Alicia Prieto Garcia, Polina Pyatilova, Michael Rudenko, Bulent Enis Sekerel, Faradiba Sarquis Serpa, Farrukh Sheikh, Frank Siebenhaar, Angèle Soria, Maria Staevska, Petra Staubach, Marcin Stobiecki, Simon Francis Thomsen, Massimo Triggiani, Anna Valerieva, Solange Valle, Nguyen Van Dinh, Carolina Elisa Vera Ayala, Anna Zalewska-Janowska, Andrea Zanichelli, Markus Magerl, Marcus Maurer
BACKGROUND: Angioedema (AE) manifests with intermittent, localized, self-limiting swelling of the subcutaneous and/or submucosal tissue. AE is heterogeneous, can be hereditary or acquired, occurs only once or be recurrent, with or without wheals, due to mast cell mediators, bradykinin or other mechanisms. Currently, different taxonomic systems are used, making it difficult to compare the results of studies, develop multicenter collaboration, and harmonize treatments of AE patients. OBJECTIVE: To develop a consensus on the definition, acronyms, nomenclature, and classification of angioedema (DANCE)...
April 24, 2024: Journal of Allergy and Clinical Immunology
#22
JOURNAL ARTICLE
Ziyi Zhao, Jiandong Wang, Weimin Kong, Ziwei Fang, Michael F Coleman, Ginger L Milne, Wesley C Burkett, Meredith A Newton, Olivia Lara, Douglas Lee, Boer Deng, Xiaochang Shen, Hongyan Suo, Wenchuan Sun, Stephen D Hursting, Chunxiao Zhou, Victoria L Bae-Jump
OBJECTIVE: Overweight/obesity is the strongest risk factor for endometrial cancer (EC), and weight management can reduce that risk and improve survival. We aimed to establish the differential benefits of intermittent energy restriction (IER) and low-fat diet (LFD), alone and in combination with paclitaxel, to reverse the procancer effects of high-fat diet (HFD)-induced obesity in a mouse model of EC. METHODS: Lkb1fl/fl p53fl/fl mice were fed HFD or LFD to generate obese and lean phenotypes, respectively...
April 25, 2024: Gynecologic Oncology
#23
JOURNAL ARTICLE
Lisa M Einhorn, Julia Hoang, Jong Ok La, Evan D Kharasch
BACKGROUND: More than 500,000 elective tonsillectomies are performed in US children annually. Pain after pediatric tonsillectomy is common, often severe, and undertreated. There is no consensus on the optimal management of perioperative tonsillectomy pain. Methadone, with an elimination half-life of 1-2 days, has a longer duration of effect than short-duration opioids such as fentanyl. The primary objective of this study was to investigate the intraoperative use of methadone for pediatric tonsillectomy...
April 26, 2024: Anesthesiology
#24
JOURNAL ARTICLE
Francesco Saverio Mennini, Paolo Sciattella, Andrea Marcellusi, Fausto Bartolini, Francesca Futura Bernardi, Fleur Levrat-Guillen, Marianna Cozzolino, Massimo Di Gennaro, Roberta Giordana, Marianna Giustozzi, Ugo Trama
INTRODUCTION: This study aims to define the distribution of direct healthcare costs for people with diabetes treated in two healthcare regions in Italy, based on number of comorbidities and treatment regimen. METHODS: This was a retrospective analysis using data from two local health authority administrative databases (Campania and Umbria) in Italy for the years 2014-2018. Data on hospital care, pharmaceutical and specialist outpatient and laboratory assistance were collected...
April 26, 2024: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
#25
JOURNAL ARTICLE
Baláš Jiří, Gajdošík Jan, Javorský Tomáš, Berta Patrik, Feldmann Andri
PURPOSE: The critical force (CF) concept, differentiating steady and non-steady state conditions, extends the critical power paradigm for sport climbing. This study aimed to validate CF for finger flexors derived from the 4 min all-out test as a boundary for the highest sustainable work intensity in sport climbers. METHODS: Twelve participants underwent multiple laboratory visits. Initially, they performed the 4 min intermittent contraction all-out test for CF determination...
April 26, 2024: European Journal of Applied Physiology
#26
JOURNAL ARTICLE
Milan Ninković, Vesna Milićević, Sonja Radojičić, Dejan Bugarski, Nataša Stević
Mycoplasma bovis ( M. bovis ) is a significant pathogen responsible for highly transmissible mastitis in cattle globally. It primarily spreads through colostrum, milk, and semen. Cows with persistent infections act as carriers, intermittently releasing the pathogen, making their milk a pivotal factor in infection transmission. Given the limited seroprevalence surveys in Serbia, this study aimed to detect M. bovis presence in bulk tank milk (BTM), determine route shedding, and evaluate infection risks. BTM samples were collected from 115 dairy farms across Serbia, with M...
April 6, 2024: Pathogens
#27
REVIEW
Sara Bernasconi, Alessandra Angelucci, Anastasia De Cesari, Aurora Masotti, Maurizio Pandocchi, Francesca Vacca, Xin Zhao, Chiara Paganelli, Andrea Aliverti
The measurement of partial pressures of oxygen (O2 ) and carbon dioxide (CO2 ) is fundamental for evaluating a patient's conditions in clinical practice. There are many ways to retrieve O2 /CO2 partial pressures and concentrations. Arterial blood gas (ABG) analysis is the gold standard technique for such a purpose, but it is invasive, intermittent, and potentially painful. Among all the alternative methods for gas monitoring, non-invasive transcutaneous O2 and CO2 monitoring has been emerging since the 1970s, being able to overcome the main drawbacks of ABG analysis...
April 9, 2024: Diagnostics
#28
JOURNAL ARTICLE
Cristina El Haj, Eugènia Agustí, Eva Benavent, Laura Soldevila-Boixader, Raül Rigo-Bonnin, Fe Tubau, Benjamín Torrejón, Jaime Esteban, Oscar Murillo
Background : As the anti-biofilm pharmacokinetic/pharmacodynamic (PK/PD) properties of antibiotics are not well-defined, we have evaluated the PK/PD indices for different regimens of ceftazidime (CAZ; with/without colistin) against Pseudomonas aeruginosa biofilm. Methods : We have used the Center for Disease Control and Prevention Biofilm Reactor with two susceptible (PAO1 and HUB-PAS) and one resistant (HUB-XDR) strains of P. aeruginosa . The regimens were CAZ monotherapies (mimicking a human dose of 2 g/8 h, CAZ-IB; 6 g/daily as continuous infusion at 50 mg/L, CAZ-CI50 ; and 9 g/daily at 70 mg/L, CAZ-CI70 ) and CAZ-colistin combinations...
April 9, 2024: Antibiotics
#29
JOURNAL ARTICLE
Dong Huang, Shuming Zhong, Xiaodong Song, Rongxu Zhang, Shunkai Lai, Yanbin Jia
No abstract text is available yet for this article.
2024: General Psychiatry
#30
JOURNAL ARTICLE
Steve Mabry, Jessica L Bradshaw, Jennifer J Gardner, E Nicole Wilson, Rebecca L Cunningham
BACKGROUND: Obstructive sleep apnea (OSA) affects 10-26% of adults in the United States with known sex differences in prevalence and severity. OSA is characterized by elevated inflammation, oxidative stress (OS), and cognitive dysfunction. However, there is a paucity of data regarding the role of sex in the OSA phenotype. Prior findings suggest women exhibit different OSA phenotypes than men, which could result in under-reported OSA prevalence in women. To examine the relationship between OSA and sex, we used chronic intermittent hypoxia (CIH) to model OSA in rats...
April 25, 2024: Biology of Sex Differences
#31
JOURNAL ARTICLE
Muhamad Faizal Zainudin, Mohd Razali Hasim, Christina Eleanor Martin, Thanalactchumy Chandrabose
INTRODUCTION: Acute transverse myelitis (ATM) is a rare neurological complication of Coronavirus disease (COVID-19) vaccines. Various vaccines have been linked to ATM, such as non-replicating viral vectors, ribonucleic acid, and inactivated vaccines. An ATM case is presented here involving the BNT162b2 vaccine leading to asymmetrical incomplete paraplegia and neurogenic bladder. CASE PRESENTATION: A 66-year-old male developed urinary retention one day after his second dose of the BNT162b2 vaccine, followed by rapidly progressing lower limb weakness...
April 25, 2024: Spinal Cord Series and Cases
#32
JOURNAL ARTICLE
Ivan H W Yim, Nigel E Drury, Hoong Sern Lim
INTRODUCTION: Intermittent cardiac output (CO) studies using thermodilution are considered the gold standard. We have developed a stroke volume (SV) calculator from pulmonary pulse pressure (PP) to allow continuous monitoring of SV and CO from PP. METHODS: Hemodynamic data on 169 patients following orthotopic heart transplantation were used to compare our calculator-derived SV (and SV index, or SVi) against thermodilution-derived SV on admission into intensive care unit immediately following heart transplantation (T0) and 6 h after admission (T6)...
April 25, 2024: Cardiology and Therapy
#33
REVIEW
Victor Ikechukwu Canice Nwagbara, John Adi Ashindoitiang, Theophilus Ipeh Ugbem, Joseph Stephen Ukam, Maurice Efana Asuquo
Intussusception is defined as the invagination of a proximal segment of the bowel into the adjoining or distal segment. In most adults with intussusception, there is a demonstrable lead point with a definite pathologic abnormality. The clinical features of intussusception include chronic intermittent abdominal pain, nausea and vomiting, constipation, and a palpable abdominal mass. The present case report describes a 62-year-old woman with a 2-week history of abdominal pain and 9-day history of vomiting. Clinical, imaging, and histologic evaluations revealed a jejunojejunal intussusception with a gastrointestinal stromal tumor as the lead point...
April 2024: Journal of International Medical Research
#34
JOURNAL ARTICLE
Juliane Carolina da Silva Santos, Raphael Mendes Ritti-Dias, Gabriel Grizzo Cucato, Nelson Wolosker, Marilia de Almeida Correia, Breno Quintella Farah
The aims of the current study were to analyze the association between the barriers to and changes in physical activity levels and sedentary behavior, as well as to examine whether these barriers change over time in patients with peripheral artery disease. In this longitudinal study, we assessed 72 patients (68% men; 65.7 ± 9.2 years). Physical activity was measured over a 7-day period using an accelerometer, and data were collected on time spent in sedentary activities, low-light physical activities, and moderate-to-vigorous physical activities...
April 24, 2024: Journal of Aging and Physical Activity
#35
JOURNAL ARTICLE
Rudra Prasad Ghorai, Siddharth Jain, Brusabhanu Nayak, Prashant Singh, Rishi Nayyar, Rajeev Kumar, Amlesh Seth
OBJECTIVES: To evaluate the long-term effectiveness and consequences of augmentation cystoplasty in adult patients with small capacity bladder due to genitourinary tuberculosis (GUTB). METHODS: After approval of the institutional ethical committee, we retrospectively analyzed the database of adult patients with small capacity bladder due to GUTB treated by augmentation cystoplasty from January 2010 to December 2022 at our center. The patients were followed up at six weeks postoperatively, then every three monthly for 1st year and six monthly in second year, and then annually...
April 23, 2024: Urology
#36
JOURNAL ARTICLE
Weam Mohamed Ebeid, Mona Kamal Abdellatif, Noha Mohsen Samak
PURPOSE: To detect structural and functional changes in children with intermittent exotropia using optical coherence tomography, pattern electroretinography (ERG), and multifocal ERG. METHODS: The study included 26 patients with intermittent exotropia and 26 healthy individuals matched for age and sex with a mean age of 9.23 and 11.20 years in the intermittent exotropia and control groups, respectively ( P = .310). All patients underwent full ophthalmic examination including measurement of the angle of strabismus at near and far, and assessment of the macula and optic nerve using optical coherence tomography, pattern ERG, and multifocal ERG...
April 25, 2024: Journal of Pediatric Ophthalmology and Strabismus
#37
JOURNAL ARTICLE
Zhenhui Huo, Kuo Hao, Chongyi Fan, Yingzhen Niu, Haotian Bai, Weixia Bai
BACKGROUND: Surgery is the main treatment for recurrent patellar dislocation (PD). However, due to the complexity of anatomical factors, there is still a lack of consensus on the choice of combined surgical methods. This study aimed to compare the clinical and radiological outcomes of medial patellofemoral ligament reconstruction combined with derotational distal femur osteotomies (MPFLR + DDFO) and combined with tibial tubercle osteotomies (MPFLR + TTO) for recurrent PD with increased femoral anteversion angles (FAA) and excessive tibial tubercle-trochlear groove (TT-TG) distance...
2024: Frontiers in Surgery
#38
Yang Xiong, Jin Li, Han-Jie Yang
BACKGROUND: Schwannomas are rare peripheral neural myelin sheath tumors that originate from Schwann cells. Of the different types of schwannomas, pelvic sciatic nerve schwannoma is extremely rare. Definite preoperative diagnosis of pelvic schwannomas is difficult, and surgical resection is the gold standard for its definite diagnosis and treatment. CASE SUMMARY: We present a case of pelvic schwannoma arising from the sciatic nerve that was detected in a 40-year-old man who underwent computed tomography for intermittent right lower back pain caused exclusively by a right ureteral calculus...
April 16, 2024: World Journal of Clinical Cases
#39
Chenxia Guo, Wei Wu, Xiang Zhu, Qingtao Zhou, Ying Liang
A 65-year-old man presented with intermittent fever and progressive shortness of breath. He responded poorly to antibiotics and corticosteroids (methylprednisolone 40 mg/d). Chest computed tomography scans showed diffuse consolidations and ground glass density patchy opacities in both lungs and these lesions progressed rapidly. The diagnosis of acute fibrinous and organizing pneumonia (AFOP) was confirmed through transbronchial cryobiopsy. This patient had prostate cancer with bone metastasis for 4 months and took the anti-prostate cancer medications including apalutamide and leuprorelin acetate...
April 2024: Respirology Case Reports
#40
Mark D Namba, Qiaowei Xie, Kyewon Park, Joshua G Jackson, Jacqueline M Barker
Cocaine use disorders (CUDs) and human immunodeficiency virus (HIV) remain persistent public health dilemmas throughout the world. One major hurdle for treating CUD is the increase in cocaine craving and seeking behavior that occurs over a protracted period of abstinence, an effect known as the incubation of craving. Little is known about how HIV may modulate this process. Thus, we sought to examine the impact of chronic HIV infection on the incubation of cocaine craving and associated changes in the central and peripheral immune systems...
April 19, 2024: bioRxiv
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