Xin-Yu Cui, Tian-Hua Liu, Ya-Li Bai, Meng-di Zhang, Guo-Dong Li, Yu-Ting Zhang, Yue-Ying Yuan, Ya-Wen Zhang, Li-Shuang Yu, Li-Na Han, Yan Wu
OBJECTIVE: To study the effect of Shexiang Tongxin Dropping Pill (STDP) on angiogenesis in diabetic cardiomyopathy mice with coronary microcirculation dysfunction (CMD). METHODS: According to a random number table, 6 of 36 SPF male C57BL/6 mice were randomly selected as the control group, and the remaining 30 mice were injected with streptozotocin intraperitoneally to replicate the type 1 diabetes model. Mice successfully copied the diabetes model were randomly divided into the model group, STDP low-dose group [15 mg/(kg·d)], medium-dose group [30 mg/(kg·d)], high-dose group [60 mg/(kg·d)], and nicorandil group [15 mg/(kg·d)], 6 in each group...
May 16, 2024: Chinese Journal of Integrative Medicine