Eline Margrete Randulff Hillestad, Elisabeth Kjelsvik Steinsvik, Erica Sande Teige, Stella Hellgren Rasmussen, Ingeborg Brønstad, Arvid Lundervold, Trygve Hausken, Kurt Hanevik, Gülen Arslan Lied, Birgitte Berentsen
BACKGROUND: A low FODMAP diet (LFD) is an established dietary treatment for patients with irritable bowel syndrome (IBS). However, knowledge on the extended effects of the restriction phase regarding nutrient intake, symptom severity, and quality of life (QoL) is sparse. Therefore, our objectives were to evaluate the safety of a dietitian-led 12-week strict LFD on measures of blood biochemistry, nutritional status, symptom severity, and QoL. METHODS: In this open-label dietitian-led 12-week strict LFD intervention for IBS patients with predominantly diarrhea or mixed stool pattern (IBS-D/-M), we collected data on diet intake (3-day dietary record), overnight fasting routine blood samples, body weight, IBS symptoms (IBS Severity Scoring System (IBS-SSS)), and IBS-related QoL (IBS-QoL) at baseline and after 12 weeks...
April 30, 2024: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society