Pulmonary hypertention

It is presented the case of a fifty years old women, diagnosed 3 years ago with systemic lupus erythematosus, under therapy with prednisone and cyclophosphamid therapy. She was admitted in our hospital for right decompensated heart disease and the presence of an apical right ventricular mass occluding part of the right ventricular cavity. The endomyocardial biopsy was made to clearify the nature of this mass. After processing the specimen, the histological study evidenciated an organizing apical thrombotic mass formed in a large right ventricular cavity in conditions of pulmonary hypertention...

Scorpion envenomation remains an important health problem in many countries in the world, especially in North Africa, Asia and America. In Algeria, the most dangerous species for humans are Androctonus australis hector (Aah) and Buthus occitanus tunetanus (Bot). These scorpions are responsible for the apparition of various symptoms in envenomed patients such as: pain, hypertention, hypotension, sudation and fever. An aggravation of clinical conditions of envenomed patients is characterized by a pulmonary cedema and myocardial damage...

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In March 1995, a 54-year-old woman was admitted to a hospital because of exertional dyspnea and her condition was diagnosed as primary pulmonary hypertension. In September 1996, respiratory difficulty and hemosputum were woted. The chest computed tomographic scan showed diffuse micronodular opacities, and she was admitted to our hospital for examination of other pulmonary conditions giving rise to pulmonary hypertention. However no lung biopsy could be performed, because the pulmonary arterial pressure was too high...

OBJECTIVE: To study hemodynamic the effects of intravenous diltiazem on COPD induced pulmonary hypertention. METHODS: 11 cases in exacerbation stage were chosen to study. Swan-Ganz catheterization were taken for hemodynamic monitoring. RESULTS: After the administration of diltiazem, pulmonary vascular resistance, pulmonary pressure, right artrial pressure and heart rate decreased significantly (the extents decreased were 14.0 kPa.s-1.L-1, 0...

Microspheres were injected intraportally to block intrahepatic portal radicals and to produce a new rat model of portal hypertention. Different sized microspheres (15 microns, 40 microns, 80 microns) were injected into the portal vein. The resultant changes in arterial, portal, hepatic venous and splenic pulp pressures were monitored. The results showed that a small-dose injection of 80 microns microspheres (1.8 x 10(5)) produced a steady state portal venous pressure of 2.53 +/- 0.17 kPa, and all rats showed a normal arterial pressure...

The effects of hypoxia on the bovine pulmonary arterial smooth muscle cell (PASM) proliferation and serotonin transporter gene expression were investigated using 3H-Thymidine incorporation, immunocytochemical staining and mRNA dot blot hybridyzation, the results were as follows, PASM 3H-Thymidine incorporation increased in response to anoxia for 24 h (P < 0.05). The anoxia-induced increased in DNA synthesis of PASM was significantly stimulated by 5-HT (100, 10 and 1 mumol/L) (P < 0.001), but 5-HT did not increase 3H-TdR incorporation under normoxic condition...

The paper deals with the treatment of the pulmonary artery hypertention in rats caused by monocrotaline with garlicin, liqustrazine and berbamine and studies the relationship between the function and structure of pulmonary artery and pulmonary artery hypertension before and after use of hypotensive agents. The results show that there is a close relationship between the function and structure of pulmonary artery and pulmonary hypertension, and the inhibitory effect of garlicin is the strongest among the three herbal medicines...

Until now the most important factor affecting the surgical treatment of ventricular septal defect (VSD) is pulmonary hypertention. 307 patients with ventricular septal defect (VSD) were treated surgically from May 1989 to May 1995 with a mortality rate of 2.9%. Among the 307 patients, 24 were complicated by severe pulmonary hypertension (Pp/Ps > or = 80%) and the mortality rate was 20.8%. Perioperative therapy and operative indications were discussed. Catheterization data, physical examination, chest X-ray and electrocardiographic findings were also analysed by comparision with operative outcome...

The patient was 43 years old female who was administrated by shortness of breath. Preoperative data including immunological examinations identified as SLE. Cardia angiogram showed PAPVC of the right pulmonary veins returned to the right atrium without ASD. Pulmonary hypertention was found with cardiac catheterizations. Open lung biopsy identified pulmonary hypertention caused by shunt volume load, but not by SLE. Surgical correction was accomplished by creating ASD and constructing a baffle to direct the blood flow from the right pulmonary veins to the left atrium...

BACKGROUND: Total cardiopulmonary bypass, in an ovine model, is associated with increased pulmonary thromboxane A2 production, cellular sequestration of white cells and platelets, transient pulmonary hypertention, and increased lung lymph flow and lymph protein clearance when compared with respective findings with partial cardiopulmonary bypass. This study evaluates the effect of neutrophil adhesion blockade on lung injury after cardiopulmonary bypass. METHODS: Two groups of anesthetized sheep were placed on total cardiopulmonary bypass without assisted ventilation...

Platelet plays an important role in thromboembolic diseases. It is demonstrated that recurrent pulmonary embolism may cause pulmonary hypertention. In recent years, P-selectin (granule membrane protein, GMP140) was found to be a surface marker for platelet activation. In order to investigate the role of platelet in chronic cor pulmonale, the changes of P-selectin on platelet membrane and its effect on platelet adhesiveness (PAdT) and platelet aggregation (PAgT) were studied. The results showed that the changes of P-selectin PAdT and PAgT in chronic cor pulmonale were significant than those in chronic pulmonary diseases and controls (P < 0...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

Indwelling pulmonary artery catheters were used for continuous monitoring of pulmonary artery pressure in ten infants with severe persistent pulmonary hypertention of the newborn. The labile nature of pulmonary artery pressure, with changes up to 50 mm Hg, was documented. Pulmonary artery pressure in the eight infants with suprasystemic pulmonary hypertension was analyzed at the time of maximum decrease in pressure (mean 36.1 mm Hg) and physiologic measurements were compared over an eight-hour period. During the study period when the infants were hyperventilated, as the Paco2 decreased from 48...