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JOURNAL ARTICLE
Bruno Levy, Nicolas Girerd, Kevin Duarte, Marie-Lauren Antoine, Luca Monzo, Ouattara Alexandre, Delmas Clément, Daniel Brodie, Alain Combes, Antoine Kimmoun, Guillaume Baudry
AIM: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has become a common intervention for patients with cardiogenic shock (CS), often complicated by cardiac arrest (CA). Moderate hypothermia (MH) has shown promise in mitigating ischemia-reperfusion injury following CA. The HYPO-ECMO trial aimed to compare the effect of MH versus normothermia in refractory CS rescued by VA-ECMO. The primary aim of this non-predefined post hoc study was to assess the treatment effect of MH in the subgroup of patients with cardiac arrest (CA) within the HYPO-ECMO trial...
May 16, 2024: Resuscitation
#2
JOURNAL ARTICLE
Silvia Mariani, Justine Mafalda Ravaux, Bas C T van Bussel, Maria Elena De Piero, Sander M J van Kruijk, Anne-Kristin Schaefer, Dominik Wiedemann, Diyar Saeed, Matteo Pozzi, Antonio Loforte, Udo Boeken, Robertas Samalavicius, Karl Bounader, Xiaotong Hou, Jeroen J H Bunge, Hergen Buscher, Leonardo Salazar, Bart Meyns, Michael A Mazzeffi, Sacha Matteucci, Sandro Sponga, Vitaly Sorokin, Claudio Russo, Francesco Formica, Pranya Sakiyalak, Antonio Fiore, Daniele Camboni, Giuseppe Maria Raffa, Rodrigo Diaz, I-Wen Wang, Jae-Seung Jung, Jan Belohlavek, Vin Pellegrino, Giacomo Bianchi, Matteo Pettinari, Alessandro Barbone, José P Garcia, Kiran Shekar, Glenn J R Whitman, Roberto Lorusso
BACKGROUND: Although cardiogenic shock requiring extracorporeal life support (ECLS) after cardiac surgery is associated with high mortality, the impact of sex on outcomes of post-cardiotomy ECLS remains unclear with conflicting results in literature. We compare patient characteristics, in-hospital outcomes, and overall survival between females and males requiring post-cardiotomy ECLS. METHODS: This retrospective, multicentre (34 centres), observational study included adults requiring post-cardiotomy ECLS between 2000 and 2020...
May 16, 2024: Journal of Thoracic and Cardiovascular Surgery
#3
JOURNAL ARTICLE
Raunak M Nair, Sanchit Chawla, Bahaa Abdelghaffar, Feras Alkhalaieh, Agam Bansal, Rishi Puri, James Yun, Amar Krishnaswamy, Samir Kapadia, Venu Menon, Grant W Reed
BACKGROUND: The aims of this study were to understand the incidence and outcomes of patients with cardiogenic shock (CS) due to severe aortic stenosis (AS), and the impact of conventional treatment strategies in this population. METHODS AND RESULTS: All patients admitted to the Cleveland Clinic cardiac intensive care unit between January 1, 2010 and December 31, 2021 with CS were retrospectively identified and categorized into those with CS in the setting of severe AS versus CS without AS...
May 18, 2024: Journal of the American Heart Association
#4
JOURNAL ARTICLE
Nadhem Abdallah, Dawn Johnson, Mark Linzer, Abdilahi Mohamoud, Mariam Abdallah, Rehan Karim
BACKGROUND: Literature illustrates an association between adverse outcomes and lower socioeconomic status (SES) in patients with critical cardiovascular presentations. Despite this, limited data exists on Complete Heart Block (CHB) outcomes in the context of SES. OBJECTIVES: We assessed the association of SES (using zip code income quartiles) with the outcomes of CHB cases. METHODS: We queried the 2016-2019 Nationwide Inpatient Sample and identified CHB as the primary diagnosis...
May 15, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
#5
Silvia Placidi, Paola Francalanci, Rachele Adorisio, Katia Girardi, Luciana Vinti, Mario Panebianco, Micol Rebonato, Antonio Amodeo, Giorgia Grutter
Findings of eosinophilic and lymphomonocytic inflammatory infiltrates in endomyocardial biopsies (EMBs) may help in myocardial disease diagnosis identification. Eosinophilic myocarditis (EM), a rare condition, is fatal if left untreated and has rarely been described in heart transplant recipients. An extensive work up is necessary to achieve an early etiological diagnosis; however, the underlying cause remains unexplained in nearly one-third of the patients. The cornerstone of treatment is corticosteroids, comprehensive therapy and heart failure management (including advanced mechanical support for fulminant myocarditis)...
2024: Frontiers in Cardiovascular Medicine
#6
Matthew Webster, Olga M Dona Lemus, Dandan Zheng, Joshua N Wancura, Sean Tanny, Gukan Sakthivel, Louis Constine
KEY CLINICAL MESSAGE: A patient presented with cardiogenic shock, requiring the implantation of a left ventricular assist device (LVAD), and acute myeloblastic leukemia. This necessitated total body irradiation (TBI) while balancing dose reduction to the LVAD components to avoid potential radiation damage. Here we outline our treatment approach and dose estimates to the LVAD. ABSTRACT: This case report discusses the delivery of TBI to a patient with an LVAD. This treatment required radiation-dose determinations and consequential reductions for the heart, LVAD, and an external controller connected to the LVAD...
May 2024: Clinical Case Reports
#7
EDITORIAL
Elizabeth A Grier, Adnan K Chhatriwalla
No abstract text is available yet for this article.
May 11, 2024: Cardiovascular Revascularization Medicine: Including Molecular Interventions
#8
JOURNAL ARTICLE
Kodai Shibao, Tatsuhiro Shibata, Chisato Kitamura, Yoshihisa Matushima, Takumi Yoshiga, Toshiyuki Yanai, Takehiro Homma, Maki Otsuka, Kenta Murotani, Yoshihiro Fukumoto
Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a therapeutic strategy for managing cardiogenic shock. However, it carries the risk of cardiogenic pulmonary edema, potentially leading to differential hypoxia. Although IMPELLA can mitigate pulmonary congestion, the combination of VA-ECMO and IMPELLA has frequently resulted in differential hypoxia, requiring a transition from VA-ECMO to veno-arteriovenous extracorporeal membrane oxygenation (VAV-ECMO). Therefore, this study aimed to examine the influence of IMPELLA on the incidence of differential hypoxia, necessitating a shift to VAV-ECMO...
May 17, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
#9
COMPARATIVE STUDY
Alejandro Sierra-González de Cossío, Diego Araiza-Garaygordobil, Nitzha A Nájera-Rojas, Alma P Alonso-Bringas, Mariana Robles-Ledesma, José Luis Briseño-de la Cruz, Rodrigo Gopar-Nieto, Héctor González-Pacheco, Daniel Sierra-Lara-Martínez, Alexandra Arias-Mendoza
BACKGROUND: The prognosis of patients with ST-segment elevation myocardial infarction (STEMI) and previous percutaneous coronary intervention (PCI) is uncertain. OBJECTIVE: To evaluate if previous PCI in patients with STEMI increases the risk of major cardiovascular events, and if final epicardial blood flow differs according to the reperfusion strategy. MATERIAL AND METHODS: Observational, longitudinal, comparative sub-study of the PHASE-MX trial that included patients with STEMI and reperfusion within 12 hours of symptom onset, who were classified according to their history of PCI...
2024: Gaceta Médica de México
#10
Francesca Fiorelli, Vasileios Panoulas, Fernando Riesgo Gil, Carl Era, Alexander Rosenberg
BACKGROUND: The use of mechanical circulatory support (MCS) has markedly increased over the last decade, so have the inter-hospital transfers, with the aim of being able to offer advanced heart failure (AHF) therapies and centralizing patients to tertiary centres. CASE SUMMARY: In this article, we present the first in Europe long-distance air transfer of a patient supported by veno-arterial extracorporeal membrane oxygenator and Impella (ECPELLA), as a bridge to successful heart transplant...
May 2024: European Heart Journal. Case Reports
#11
REVIEW
Jarosław Mazuryk, Katarzyna Klepacka, Włodzimierz Kutner, Piyush Sindhu Sharma
Glyphosate (GLP) is an active agent of GLP-based herbicides (GBHs), i.e., broad-spectrum and postemergent weedkillers, commercialized by Monsanto as, e.g., Roundup and RangerPro formulants. The GBH crop spraying, dedicated to genetically engineered GLP-resistant crops, has revolutionized modern agriculture by increasing the production yield. However, abusively administered GBHs' ingredients, e.g., GLP, polyoxyethyleneamine, and heavy metals, have polluted environmental and industrial areas far beyond farmlands, causing global contamination and life-threatening risk, which has led to the recent local bans of GBH use...
May 10, 2024: ACS Pharmacology & Translational Science
#12
JOURNAL ARTICLE
Misa Kusumoto, Jumpei Yamamoto, Sakura Kaneda, Takuya Matsushiro, Masaya Yamamoto, Hisao Hara, Nobuyuki Inoue, Yukio Hiroi
A 55-year-old man presented to the emergency department with worsening shortness of breath 1 month after a gastrointestinal bleed. He had congestive heart failure, and an electrocardiogram suggested ischemic heart disease involvement. Echocardiography revealed a ventricular septal defect complicated by a left ventricular aneurysm in the inferior-posterior wall. Conservative treatment was started, but hemodynamic collapse occurred on the third day of admission and coronary angiography revealed a revascularizing lesion in the right fourth posterior descending coronary artery...
May 15, 2024: International Heart Journal
#13
Magdoud Khaoula, Bayar Sirine, Menjli Sana, Azouz Eya, Sahraoui Ghada, Mrad Karima
INTRODUCTION: Primary breast sarcoma (PBS), excluding phyllodes tumors, is an extremely rare and heterogeneous group of cancers, accounting for <1 % of all breast cancers. PBS is typically diagnosed in the fifth or sixth decades of life. There are no pathognomonic clinical or radiological features. Diagnosis is generally established through a microbiopsy. For young women, the diagnosis can be confused with a benign pathology. CLINICAL PRESENTATION: Our patient was 27 years old, with no family or personal history of breast cancer, which was initially brought to the emergency department with a breast abscess...
March 28, 2024: International Journal of Surgery Case Reports
#14
JOURNAL ARTICLE
Maggie S Chen, Rujie Sun, Richard Wang, Yuyang Zuo, Kun Zhou, Junyoung Kim, Molly M Stevens
Many cardiac diseases, such as arrhythmia or cardiogenic shock, cause irregular beating patterns that must be regulated to prevent disease progression towards heart failure. Treatments can include invasive surgery or high systemic drug dosages, which lack precision, localization, and control. Drug delivery systems (DDSs) that can deliver cargo to the cardiac injury site could address these unmet clinical challenges. Here, we present a microrobotic DDS that can be mobilized to specific sites via magnetic control...
May 15, 2024: Advanced Healthcare Materials
#15
Irene Carrión-Sánchez, Carlos Tejada-González, Jennifer Gómez-Delgado, Rocio Párraga, Javier Cobiella, Jose Alberto de Agustín, Eduardo Pozo-Osinalde, Alberto García-Lledó
BACKGROUND: Intramyocardial dissection (ID) is an extremely rare myocardial infarction mechanical complication. Although both clinical and imaging assessment of this rare condition remains a challenge, recent multimodality imaging techniques may help to confirm and to assess the progressive nature of the disease. Diagnosis may be reached in different stages, from as early as the intramyocardial dissecting haematoma to the severe false-pseudoaneurysm. CASE SUMMARY: This series describes five cases of ID and provides insights into imaging findings and clinical course of this extremely uncommon condition...
May 2024: European Heart Journal. Case Reports
#16
JOURNAL ARTICLE
Mark Dennis, Aidan Burrell, Sean Lal, Caleb Ferguson, John French, Emma Bowcock, Natalie Kruit, Brian Burns, Pankaj Jain
BACKGROUND: Cardiogenic shock (CS) is common and survival outcomes have not substantially improved. Australia's geography presents unique challenges in the management of CS. The challenges and research priorities for clinicians pertaining to CS identification and management have yet to be described. METHOD: We used an exploratory sequential mixed methods design. Semi-structured interviews were conducted with 10 clinicians (medical and nursing) to identify themes for quantitative evaluation...
May 13, 2024: Heart, Lung & Circulation
#17
JOURNAL ARTICLE
Batric Popovic, Jeanne Varlot, Lisa Humbertjean, Jean Marc Sellal, Nathalie Pace, Nefissa Hammache, Renaud Fay, Florian Eggenspieler, Pierre Adrien Metzdorf, Edoardo Camenzind
BACKGROUND: The prevalence and impact of coronary emboli (CE) in patients with ST-segment-elevation myocardial infarction (STEMI) and atrial fibrillation (AF) have not been specifically studied. The objective was to describe the clinical characteristics and outcomes of patients with AF and CE in a large series of patients with STEMI. METHODS AND RESULTS: We investigated 2292 consecutive patients with STEMI and among them 225 patients with AF: 46 patients with a STEMI related to CE (group A) and 179 patients with a STEMI related to an atherosclerotic cause (group B)...
May 14, 2024: Journal of the American Heart Association
#18
REVIEW
Megan E Campany, Britton B Donato, Pedro Reck Dos Santos, Cory M Alwardt, Kristin Sell-Dottin, Stephanie Blakeman, Penny Hung, Ayan Sen, Patrick DeValeria, Lara Schaheen, Jonathan D'Cunha
BACKGROUND AND OBJECTIVE: Extracorporeal membrane oxygenation (ECMO) has historically been utilized as a temporary life support option for patients with severe cardiac and pulmonary dysfunction. Recent advancements have enabled the safe application of ECMO in a wider variety of patients; we present a review of its use in patients undergoing general thoracic procedures supported by a case series at our institution. METHODS: We review current literature focusing on ECMO applications in thoracic surgery outside of the traditional use...
April 30, 2024: Journal of Thoracic Disease
#19
JOURNAL ARTICLE
Rupak Desai, Nishanth Katukuri, Sai Gautham Kanagala, Nitin Ghadge, Alpha James, Borzoo Tajdin, Akhila Nalla, Sai Diksha Vutukuru, Devi Meghana Kotharu, Avinash Kadiyala, Ankit Vyas, Priyadarshi Prajjwal, Ikechukwu Ogbu
Pulmonary hypertension (PH) often complicates idiopathic pulmonary fibrosis (IPF), a progressive parenchymal lung disease. We investigated predictors of PH in IPF hospitalizations in the United States. We identified IPF hospital- izations with or without PH using the National Inpatient Sample (2018) and relevant ICD-10-CM codes. We com- pared demographics, comorbidities, PH prevalence, and its multivariable predictors adjusted for confounders among patients with IPF. In 2018, 30,335 patients from 30,259,863 hospitalizations had IPF, of which 8,075 (26...
January 2024: Journal of Medicine and Life
#20
JOURNAL ARTICLE
Alex Warren, Philip McCall, Alastair Proudfoot, Stuart Gillon, Ahmad Abu-Arafeh, Angus John McKnight, Rosemary Mudie, David Armstrong, Evangelos Tzolos, John Andrew Livesey, Andrew Sinclair, Veronica Baston, Jonathan Dalzell, Deborah Owen, Lucy Fleming, Ian Scott, Alex Puxty, Matthew My Lee, Fiona Walker, Simon Hobson, Euan Campbell, Michael Kinsella, Eilidh McGinnigle, Robert Docking, Grant Price, Alex Ramsay, Richard Bauld, Suzanne Herron, Nazir I Lone, Nicholas L Mills, Louise Hartley
BACKGROUND: Despite high rates of cardiovascular disease in Scotland, the prevalence and outcomes of patients with cardiogenic shock are unknown. METHODS: We undertook a prospective observational cohort study of consecutive patients with cardiogenic shock admitted to the intensive care unit (ICU) or coronary care unit at 13 hospitals in Scotland for a 6-month period. Denominator data from the Scottish Intensive Care Society Audit Group were used to estimate ICU prevalence; data for coronary care units were unavailable...
May 2024: Journal of the Intensive Care Society
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