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REVIEW
Warren Bacorro, Michala Short, Kathleen Baldivia, Jocelyn Mariano, Aida Bautista, Genalin Amparo, Irene Tagayuna, Carl Jay Jainar, Linda Antonio, Evelyn Dancel, Teresa Sy Ortin, Gil Gonzalez, Rodel Canlas
PURPOSE: Shared decision making (SDM) is an approach where clinicians and patients make decisions together using the best available evidence. Although much studied, recognized to be ethically imperative, and recommended in international health policies, it remains poorly implemented. In the Philippines, there are limited studies on patient decision making preferences and SDM. Practical guidance on the implementation of SDM or use of patient decision aids (PtDAs) is often not detailed in existing national clinical practice guidelines in oncology...
May 2024: JCO global oncology
#82
JOURNAL ARTICLE
Paulo Valderrama, Romina Carugati, Angela Sardella, Sandra Flórez, Isabela de Carlos Back, Carlos Fernández, Inés T Abella, Angelica Grullón, Aida Luiza Ribeiro Turquetto, Astrid Fajardo, Pedro Chiesa, Barbara Cifra, Luisa Garcia-Cuenllas, Michele Honicky, Luiz Rodrigo Augustemak De Lima, Yara María Franco Moreno, María Eugenia Salinas, Tales de Carvalho, Liane Hülle Catani, Manuel Huertas-Quiñones, Lucelli Yáñez-Gutiérrez
The 2024 Interamerican Society of Cardiology (SIAC) guidelines on cardiorespiratory rehabilitation (CRR) in pediatric patients with congenital heart disease aim to gather and evaluate all relevant evidence available on the topic to unify criteria and promote the implementation of CRR programs in this population in Latin America and other parts of the world. Currently, there is no unified CRR model for the pediatric population. Consequently, our goal was to create these CRR guidelines adapted to the characteristics of congenital heart disease and the physiology of this population, as well as to the realities of Latin America...
May 13, 2024: Revista Española de Cardiología
#83
JOURNAL ARTICLE
Aida S Badiane, Bassirou Ngom, Tolla Ndiaye, Deirdre Cunningham, James Campbell, Amy Gaye, Aita Sène, Mouhamad Sy, Daouda Ndiaye, Davis Nwakanma, Jean Langhorne
BACKGROUND: Malaria elimination in Senegal requires accurate diagnosis of all Plasmodium species. Plasmodium falciparum is the most prevalent species in Senegal, although Plasmodium malariae, Plasmodium ovale, and recently Plasmodium vivax have also been reported. Nonetheless, most malaria control tools, such as Histidine Rich Protein 2 rapid diagnosis test (PfHRP2-RDT,) can only diagnose P. falciparum. Thus, PfHRP2-RDT misses non-falciparum species and P. falciparum infections that fall below the limit of detection...
May 16, 2024: Malaria Journal
#84
JOURNAL ARTICLE
Stefan Wiesler, Goh Sennari, Mihai V Popescu, Kristen E Gardner, Kazuhiro Aida, Robert S Paton, Richmond Sarpong
Skeletal modifications enable elegant and rapid access to various derivatives of a compound that would otherwise be difficult to prepare. They are therefore a powerful tool, especially in the synthesis of natural products or drug discovery, to explore different natural products or to improve the properties of a drug candidate starting from a common intermediate. Inspired by the biosynthesis of the cephalotane natural products, we report here a single-atom insertion into the framework of the benzenoid subfamily, providing access to the troponoid congeners - representing the reverse of the proposed biosynthesis (i...
May 15, 2024: Nature Communications
#85
JOURNAL ARTICLE
Naziia Kurmasheva, Aida Said, Boaz Wong, Priscilla Kinderman, Xiaoying Han, Anna H F Rahimic, Alena Kress, Madalina E Carter-Timofte, Emilia Holm, Demi van der Horst, Christoph F Kollmann, Zhenlong Liu, Chen Wang, Huy-Dung Hoang, Elina Kovalenko, Maria Chrysopoulou, Krishna Sundar Twayana, Rasmus N Ottosen, Esben B Svenningsen, Fabio Begnini, Anders E Kiib, Florian E H Kromm, Hauke J Weiss, Daniele Di Carlo, Michela Muscolini, Maureen Higgins, Mirte van der Heijden, Angelina Bardoul, Tong Tong, Attila Ozsvar, Wen-Hsien Hou, Vivien R Schack, Christian K Holm, Yunan Zheng, Melanie Ruzek, Joanna Kalucka, Laureano de la Vega, Walid A M Elgaher, Anders R Korshoej, Rongtuan Lin, John Hiscott, Thomas B Poulsen, Luke A O'Neill, Dominic G Roy, Markus M Rinschen, Nadine van Montfoort, Jean-Simon Diallo, Henner F Farin, Tommy Alain, David Olagnier
The presence of heterogeneity in responses to oncolytic virotherapy poses a barrier to clinical effectiveness, as resistance to this treatment can occur through the inhibition of viral spread within the tumor, potentially leading to treatment failures. Here we show that 4-octyl itaconate (4-OI), a chemical derivative of the Krebs cycle-derived metabolite itaconate, enhances oncolytic virotherapy with VSVΔ51 in various models including human and murine resistant cancer cell lines, three-dimensional (3D) patient-derived colon tumoroids and organotypic brain tumor slices...
May 15, 2024: Nature Communications
#86
Sureni V Mullegama, Kaitlyn A Kiernan, Erin Torti, Ethan Pavlovsky, Nicholas Tilton, Austin Sekula, Hua Gao, Joseph T Alaimo, Kendra Engleman, Eric T Rush, Karli Blocker, Katrina M Dipple, Veronica M Fettig, Heather Hare, Ian Glass, Dorothy K Grange, Michael Griffin, Chanika Phornphutkul, Lauren Massingham, Lakshmi Mehta, Danny E Miller, Jenny Thies, J Lawrence Merritt, Eric Muller, Matthew Osmond, Sarah L Sawyer, Rachel Slaugh, Rachel E Hickey, Barry Wolf, Sanjeev Choudhary, Miljan Simonović, Yueqing Zhang, Timothy Blake Palculict, Aida Telegrafi, Deanna Alexis Carere, Ingrid M Wentzensen, Michelle M Morrow, Kristin G Monaghan, Jane Juusola, Jun Yang
No abstract text is available yet for this article.
May 14, 2024: American Journal of Human Genetics
#87
JOURNAL ARTICLE
Marta Cossetin Costa, Maria de Fátima Mantovani, Fernanda Moura D'Almeida Miranda, Ivonete Teresinha Schülter Buss Heidemann, Aida Maris Peres
OBJECTIVE: to understand the Generalized Resistance Deficits of people deprived of liberty with hypertension in a Brazilian prison unit. METHOD: qualitative research, anchored in Salutogenesis, carried out with 38 people with hypertension from a Brazilian prison unit, from February to July 2022, with a semi-structured interview with open-ended questions, whose analysis was thematic, explaining the limitations to health in prison. RESULTS: 13 Generalized Resistance Deficits were reported, mostly related to the prison environment and, to a lesser extent, to the social group and the individual, respectively...
2024: Revista Brasileira de Enfermagem
#88
JOURNAL ARTICLE
Nihel Khouja, Jihen Hsinet, Kais Abdennadher, Emna Baraketi, Saloua Ismail, Amani Dallagi, Sami Abdelfattah, Aida Benzarti Mezni
INTRODUCTION: Musculoskeletal disorders (MSDs) are as the primary occupational disease (OD) in Tunisia. They can touch the elbow and cause occupational disability. AIMS: Describe the epidemiological and clinical characteristics of elbow MSDs recognized in Tunisia, identify the factors associated with these MSDs and assess their socio-professional impact. METHODS: Retrospective descriptive study of elbow MSDs recognized as compensable OD by the Committees for the Recognition of Occupational Diseases of National Health Insurance Fund, in Tunisia, from 2012 to 2018...
April 5, 2024: La Tunisie Médicale
#89
RANDOMIZED CONTROLLED TRIAL
Ahlem Trifi, Aida Benzarti, Asma Mehdi, Eya Seghir, Lynda Messaoud, Sami Abdellatif
INTRODUCTION: In intensive care medicine (ICM), the use of Patient-Management Problem (PMP) remains limited and no feedback from students is available. AIM: To compare the feasibility of employing PMP referring to clinical cases (CC) as assessment tools for appraising the knowledge and competencies in ICM students; and to gather the students' perception regarding this experience. METHODS: it was a cross-sectional randomized trial. Were included, external students in the 3rd year of the 2nd cycle of medical studies (3rd-SCMS) during their ICM externship...
April 5, 2024: La Tunisie Médicale
#90
REVIEW
Sarra Ben Azouz, Nour Elleuch, Wafa Dahmeni, Eya Hammami, Ahlem Braham, Hanene Jaziri, Aida Ben Slema, Mehdi Ksiaa, Ali Jmaa
INTRODUCTION: Treatment of complex perianal fistulas in Crohn's disease remains a challenge especially after the failure of Infliximab. AIM: Update on the different therapeutic alternatives for anal fistula in Crohn's disease after failure of Infliximab. METHODS: A research in the medical literature on PubMed and Google Scholar was carried out. We included cohort studies, reviews and randomized double-blinded therapeutic trials. Case reports and fundamental research studies have been excluded...
April 5, 2024: La Tunisie Médicale
#91
REVIEW
Leila Zaki, Meysam Olfatifar, Fatemeh Ghaffarifar, Aida Vafae Eslahi, Amir KarimiPourSaryazdi, Ali Taghipour, Najla Hamidianfar, Milad Badri, Pikka Jokelainen
Among the potential animal reservoirs of the zoonotic parasite T. gondii , birds have received relatively little attention. This systematic review and meta-analysis aimed to assess the global status and to provide an overview of the epidemiology of T. gondii infection in birds. The standard protocol of preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines were followed. Scopus, PubMed, Web of Science, Science Direct, ProQuest, and Google Scholar were searched for relevant publications from January 1990, to March 2024...
May 2024: Parasite Epidemiology and Control
#92
JOURNAL ARTICLE
Masoud Naderpour, Yalda Jabbari Moghaddam, Amin Abbasi, Aida Ariafar, Bita Poorshiri
INTRODUCTION: Cochlear implants (CI) provide a hearing sense for severe to profound hearing-impaired patients, both adults and children, and they are a broadly effective and accepted therapeutic method for those patients. Also, Deaf children with comorbidities, including autism spectrum disorders (ASDs), undergo cochlear implantation. ASDs are a group of developing disorders characterized by abnormalities in social interaction and communication with limited repetitive patterns of behavior...
May 2024: Iranian Journal of Otorhinolaryngology
#93
JOURNAL ARTICLE
Juliane Rolim de Lavôr, Adriana Mendonça da Silva, Jenny Bogstad Søvik, Aronita Rosenblatt, Aida Mulic, Alexandre Rezende Vieira
INTRODUCTION: Erosive tooth wear (ETW) is a multifactorial condition of increasing prevalence in the younger population. This study aimed to explore the association between different ETW phenotypes with MMP2 and COMT single-nucleotide variants, and selected environmental factors. METHODS: Saliva samples, erosive wear and dental caries experience data, and dietary/behavioral information from 16-18-year-old patients (n= 747) were used. Genotypes were obtained and phenotypes were further analyzed considering diet and behavioral data, using logistic regression as implemented in PLINK, with an alpha of 0...
May 14, 2024: Caries Research
#94
JOURNAL ARTICLE
Emil Moiş, Florin Graur, Cosmin Puia, Iulia Vlad, Septimiu Moldovan, Cristina Paula Ursu, Vlad-Ionuţ Nechita, Dan Vălean, Luminiţa Furcea, Aida Puia, Florin Zaharie, Călin Popa, Raluca Bodea, Cornel Iancu, Ioana Rusu, Nadim Al Hajjar
Background: Pancreatic Ductal Adenocarcinoma (PDAC) is a pathology with a very poor prognostic, the only curative treatment option being surgery, in association with chemotherapy. This study aims to assess the influence that the use of a standardized pathology report after a pancreaticoduodenectomy (PD) has on the R1 margins rate and the impact that this has on long term survival. Material and Methods: We included 116 patients admitted to the Regional Institute of Gastroenterology and Hepatology Prof. Dr. O...
April 2024: Chirurgia
#95
JOURNAL ARTICLE
Lidia Rudnicka, Magdalena Trzeciak, Erkan Alpsoy, Petr Arenberger, Sibel Alper, Nina Benáková, Svetlana Bobko, Murat Borlu, Magdalena Czarnecka Operacz, Burhan Engin, Tülin Ergun, Ilgen Ertam Sağduyu, Olga Filipovská, Aida Gadzhigoroeva, Martina Kojanová, Aleksandra Lesiak, Anna Michenko, Nikolay Murashkin, Nahide Onsun, Witold Owczarek, Zuzana Plzakova, Adam Reich, Marie Selerová, Burcu Aybike Gürbüz
OBJECTIVES: This study aims to update the understanding of Alopecia Areata (AA) in Poland, Czechia, Russia, and Türkiye, focusing on the disease burden, clinical management, and patient journey. It seeks to establish a consensus on optimal management strategies for AA in these regions. METHODS: A modified 2-round Delphi panel was conveyed with 23 Dermatologists (Russia; 4, Türkiye; 7, Poland; 6, and Czechia; 6). The Delphi questionnaire consisted of 61 statements and 43 questions designed to obtain an overall understanding of the perception and acceptance of available information regarding the care of patients with alopecia areata...
2024: Frontiers in Medicine
#96
JOURNAL ARTICLE
Yongqiang Ma, Aida Bao, Xin Guo, Jie Wang
In this paper, a new GaSe/ZnS van der Waals heterostructure (vdWH) was constructed and a systematic analysis of the electronic structure, interfacial properties, and transport and photocatalytic capacity of the GaSe/ZnS vdWH was performed by using first-principles calculations. It was found that the heterostructure exhibited excellent photocatalytic performance for water splitting. The direct band gap of the heterostructure calculated using the hybrid HSE06 functional was 2.19 eV, which had a good visible light absorption ability...
May 13, 2024: Physical Chemistry Chemical Physics: PCCP
#97
JOURNAL ARTICLE
Ramin Raoufinia, Hamid Reza Rahimi, Mahla Abbaszadeh, Aida Gholoobi, Ehsan Saburi, Farhad Fakoor, Hawraa Ibrahim Alshakarchi, Ibrahim Saeed Gataa, Seyed Mahdi Hassanian, Gordon A Ferns, Majid Khazaei, Amir Avan
Cardiovascular diseases place a considerable burden on global health systems, contributing to high rates of morbidity and mortality. Current approaches to detecting and treating Cardiovascular Diseases (CVD) often focus on symptomatic management and are initiated after the disease has progressed. Personalized medicine, which tailors medical interventions to individual characteristics, has emerged as a promising strategy for improving cardiovascular health outcomes. This article provides an overview of personalized medicine in the context of CVD, with a specific emphasis on FDA-approved interventions...
May 10, 2024: Current Pharmaceutical Design
#98
Ali Ghorbani, Nicholas R Munoz, Syed Ahmed, Salma Yasin, Sophia Ho, Aida Ghorbani, Kurosh Zamiri
Widely distributed in the central nervous system (CNS), N-methyl-D-aspartate receptors (NMDARs) are believed to be involved in long-term potentiation, essential in regulating and forming memory. This condition primarily occurs in young females because of autoantibodies forming against the N-methyl-D-aspartate receptor-1 (NR1) or N-methyl-D-aspartate receptor-2 (NR2) subunits of NMDAR in the CNS, ultimately portraying a unique psychoneurological phenomenon. Patients with antibodies against NMDAR present with a combination of neurological and psychiatric signs and symptoms...
April 2024: Curēus
#99
JOURNAL ARTICLE
Sara Calvo-Silveria, Aida González-Díaz, Inmaculada Grau, José María Marimón, Emilia Cercenado, M Dolores Quesada, Antonio Casabella, Nieves Larrosa, José Yuste, Dàmaris Berbel, Marta Alonso, Fe Tubau, Sophie Belman, Irene Cadenas-Jiménez, Antonio J Martín-Galiano, M Ángeles Domínguez, Sara Martí, Josefina Liñares, Román Pallarés, Jordi Càmara, Carmen Ardanuy
BACKGROUND: Invasive pneumococcal disease due to serotype 3 (S3-IPD) is associated with high mortality rates and long-term adverse effects. The introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) into the Spanish paediatric immunisation programme has not led to a decrease in the adult S3-IPD. We aimed to analyse the incidence, clinical characteristics and genomics of S3-IPD in adults in Spain. METHODS: Adult IPD episodes hospitalized in a Southern Barcelona hospital were prospectively collected (1994-2020)...
June 2024: The Lancet regional health. Europe
#100
JOURNAL ARTICLE
Hans Hämäläinen, Antti O Tanskanen, Bruno Arpino, Aïda Solé-Auró, Mirkka Danielsbacka
Studies have shown that retired older adults are more likely to volunteer than their working counterparts. However, whether the transition to retirement is associated with increased volunteering frequency and whether this varies according to material and time resources of participants is unclear. We used four waves of data from the longitudinal Survey of Health, Ageing and Retirement in Europe, collected between 2011-2018 across 19 countries ( n = 12,400 person-observations from 6200 individuals over 50). Within-person (or panel fixed-effect) regression analyses revealed that transition to retirement was associated with an increased volunteering frequency over time...
May 10, 2024: Research on Aging
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