Gaini Ma, Xiaoye Huang, Yan Bi, Fei Xu, Weibo Niu, Decheng Ren, Qianqian Sun, Zhenming Guo, Ruixue Yuan, Fan Yuan, Xi Wu, Fengping Yang, Lu Wang, Weidong Li, Lin He, Tao Yu, Xingwang Li, Jie Liu, Guang He
BACKGROUND: Schizophrenia (SCZ) is a complex, heritable, and devastating psychiatric disorder. Mutations in the members of ABC transporters have been associated with psychiatric illnesses. AIMS: In this study, we investigated whether 9 SNPs in ABCB1 (rs6946119, rs28401781, rs4148739, and rs3747802), ABCB6 (rs1109866, rs1109867, rs3731885, and rs3755047), and ABCG1 (rs182694) contribute to the risk of SCZ in a Han Chinese population. METHODS: We conducted a case-control study in a Han Chinese population, involving 1,034 SCZ patients and 1,034 unrelated healthy controls to genotype 9 SNPs...
June 12, 2019: Neuropsychobiology