Anthony Price, Christopher File, Francisco Call-Orellana, Romulo Augusto Andrade de Almeida, Robert Y North
BACKGROUND: Paget's disease of bone (PDB) is a common bone metabolic pathology in older adults, characterized by mixed osteolytic, osteoblastic, and quiescent periods. Surgical guidelines for PDB involving the spine are not well-defined and are reserved for cases refractory to medical treatments, typically bisphosphonates like zoledronic acid. This case study describes a 52-year-old male with PDB who presented with rapidly progressing myelopathy symptoms refractory to standard medical treatment, warranting surgical decompression...
July 22, 2024: J Neurosurg Case Lessons
Hongping Chen, Jinmei Li
OBJECTIVE: To explore and analyze the comprehensive nursing effect of percutaneous vertebroplasty (PVP) in the treatment of elderly patients with thoracolumbar vertebral compression fractures. METHODS: This study recruited elderly patients with thoracolumbar vertebral compression fractures who were diagnosed in Lujiang County People's Hospital from January 2020 to December 2022 and underwent PVP. Finally, a total of 80 cases were included in this study. All patients were randomly divided into two treatment groups: the observation group and the control group...
July 19, 2024: Alternative Therapies in Health and Medicine
Xuxuan Wang, Yabin Zhang, Yiguo Wang, Yihao Liu, Xiucan Li, Zhenchuan Han, Yongfei Zhao, Bo Wang, Jianheng Liu, Runsheng Wang, Keya Mao
PURPOSE: The aim of the study was to evaluate the feasibility of a bioabsorbable cage consisting of magnesium and magnesium phosphate cement (MPC) in a porcine lumbar interbody fusion model. METHODS: Twelve male Ba-Ma mini pigs underwent lumbar discectomy and fusion with an Mg-MPC cage or a PEEK cage at the L3/L4 and L4/L5 level. Computed tomography (CT) scans were made to evaluate the distractive property by comparing average disc space height (DSH) before and at 6, 12, and 24 weeks after the operation...
July 22, 2024: European Spine Journal
Shinjan Patra, Hiya Boro, Pradakshna Porchezhian, Naila Khan, Minal Pande
UNLABELLED: Pheochromocytoma and paraganglioma (PPGL) have been associated with low bone mineral density (BMD) due to excess sympathetic system stimulation. Our study revealed low BMD and TBS (trabecular bone score) in cases compared to matched controls. Plasma-free nor-metanephrine and hypertension duration found to be most consistent predictive factors. PURPOSE: Pheochromocytoma and paraganglioma (PPGL) have been associated with low bone mineral density (BMD) and increased fracture risks...
July 22, 2024: Osteoporosis International
Venkatram Krishnan, Sriram Jaganathan, Arabinda K Choudhary, Xiawei Ou, Rhea Choudhary, Anya Choudhary, Xiaoxu Na, Kshitij Mankad, Raghu Ramakrishnaiah, Sateesh Jayappa
BACKGROUND: Intracranial birth-related subdural hemorrhage frequently occurs in asymptomatic newborns and has no adverse long-term sequelae. It is medically and medicolegally important to differentiate birth-related subdural hemorrhage from other pathological causes of intracranial hemorrhage. There is limited literature available on the incidence of birth-related subdural hemorrhage, its imaging features, and evolution over time, mainly because asymptomatic infants do not routinely undergo cranial MRI...
July 22, 2024: Pediatric Radiology
Sudeep Sarma, Tarunya Rao Sudarshan, Van Nguyen, Alicia S Robang, Xingqing Xiao, Justin V Le, Michael E Helmicki, Anant K Paravastu, Carol K Hall
Peptide self-assembly into amyloid fibrils provides numerous applications in drug delivery and biomedical engineering applications. We augment our previously-established computational screening technique along with experimental biophysical characterization to discover 7-mer peptides that self-assemble into "parallel β-sheets", that is, β-sheets with N-terminus-to-C-terminus 𝛽-strand vectors oriented in parallel. To accomplish the desired β-strand organization, we applied the PepAD amino acid sequence design software to the Class-1 cross-β spine defined by Sawaya et al...
August 2024: Protein Science
Diwas Gautam, Sheela Vivekanandan, Marcus D Mazur
BACKGROUND AND OBJECTIVES: Robotic systems have emerged as a significant advancement in the field of spine surgery. They offer improved accuracy in pedicle screw placement and reduce intraoperative complications, hospital length of stay, blood loss, and radiation exposure. As the use of robotics in spine surgery continues to grow, it becomes imperative to understand common errors and challenges associated with this new and promising technology. Although the reported accuracy of robot-assisted pedicle screw placement is very high, the current literature does not capture near misses or incidental procedural errors that might have been managed during surgery or did not alter treatment of patients...
July 22, 2024: Operative Neurosurgery (Hagerstown, Md.)
Robin M Babadjouni, Nakul Narendran, Paal K Nilssen, Alexander Tuchman, Corey T Walker
The thoracolumbar junction is a complex and challenging anatomical region due to its heterogeneous array of planes and structures.1 Navigating this region during a lateral approach to the spine is a challenge that requires a thorough understanding of the anatomy. We present a case of a 54-year-old woman with a 7-year history of breast cancer who presented with low back pain after running a marathon. To date, the patient had deferred medical management. Imaging revealed Stage IV differentiated invasive ductal carcinoma with extensive bony metastatic disease in multiple areas of the spine...
July 22, 2024: Operative Neurosurgery (Hagerstown, Md.)
Zongqiang Yang, Long Ma, Zhangui Gu, Ningkui Niu, Jiandang Shi
The spine is a common site for metastatic tumors, with 5%-10% of patients developing epidural spinal cord compression (ESCC), which significantly reduces their quality of life and accelerates the process of death. When total en-bloc spondylectomy (TES) radical surgery does not achieve the desired tumor control, palliative care remains the primary treatment option. Traditional laminar decompression or partial tumor resection can only relieve local compression. Although the surgical trauma and complications are less, these methods cannot effectively address tumor recurrence and secondary compression...
July 5, 2024: Journal of Visualized Experiments: JoVE
Shuichiro Kurita, Kenta Furutani, Yusuke Mitsuma, Hiroyuki Deguchi, Tomoaki Kamoda, Yoshinori Kamiya, Hiroshi Baba
BACKGROUND: Some anesthetic drugs reduce the amplitude of transcranial electrical motor-evoked potentials (MEPs). Remimazolam, a new benzodiazepine, has been suggested to have little effect on MEP amplitude. This prospective, preliminary, dose-escalation study aimed to assess whether remimazolam is associated with lower MEP amplitude in a dose-dependent manner. METHODS: Ten adult patients scheduled for posterior spinal fusion were included in this study. General anesthesia was induced with a continuous infusion of remifentanil and remimazolam...
July 22, 2024: Journal of Neurosurgical Anesthesiology
Manar H Abu Khurmah, Mohammad J Alkhatatbeh, Osama Y Alshogran, Hamza M Alarda
OBJECTIVES: Our aim was to predict the prevalence of osteopenia and osteoporosis and their associated risk factors among postmenopausal women from Jordan. METHODOLOGY: In this cross-sectional study, a total of 368 postmenopausal women were recruited from King Abdullah University Hospital (KAUH) in the North of Jordan between September 2022 and April 2023. Bone mineral density (BMD) was measured using a dual-energy X-ray absorptiometry scan. T-score was used for osteoporosis diagnosis in accordance with the International Society for Clinical Densitometry (ISCD) guidelines...
July 22, 2024: Public Health Nursing
Anjishnu Banerjee, Yushan Yang, Marjorie C Wang, Aditya Vedantam
STUDY DESIGN: Retrospective study. OBJECTIVE: The aim of this study was to identify recovery trajectory clusters after surgery for degenerative cervical myelopathy (DCM), as well as to determine clinical and imaging characteristics associated with functional recovery trajectories. BACKGROUND: Accurate prediction of postsurgical neurological recovery for the individual patient with DCM is challenging due to varying patterns of functional recovery...
July 22, 2024: Clinical Spine Surgery
Matthew H Meade, Mark Michael, Jamie Henzes, Ruchir Nanavati, Barrett Woods
The abstract of a research paper functions to attract readers and highlight the clinical significance of a research project in a broadly appealing manner. Abstract structure is commonly dictated by the target journal, however, a basic style typically follows the "Introduction, Methods, Results and Discussion" structure of introduction, materials/methods, results, and discussion/conclusion. The abstract itself is commonly the initial accessible portion of a research paper, so writing in an engaging while informative manner is imperative for increasing manuscript views and citations...
July 22, 2024: Clinical Spine Surgery
Matthew H Meade, Levi Buchan, Mark Michael, Barrett Woods
With the vast increase in spinal surgery research and accessibility, critical evaluation of studies is paramount. Historically, P values and confidence intervals have been the gold standard, but more recently, the inclusion of the Fragility Index has brought a more holistic approach. The Fragility Index aims to communicate the robustness of a trial and how tenuous statistical significance may be. It can be used in conjunction with more traditional methods for evaluating research.
July 22, 2024: Clinical Spine Surgery
Maia Osborne-Grinter, Phillip Copley, Sadaquate Khan, Chandrasekaran Kaliaperumal
INTRODUCTION: Parkinson's disease is a common neurodegenerative disease. With an aging population, co-existent degenerative diseases of the spine in these patients will become more prevalent. RESEARCH QUESTION: This systematic review and meta-analysis aims to establish the incidence and risk of adverse outcomes following spinal surgery in patients with Parkinson's disease. Material and Methods A literature review was carried out in order to identify studies assessing the outcomes of adult patients with Parkinson's disease undergoing spinal surgery for degenerative conditions...
July 22, 2024: British Journal of Neurosurgery
Camille Vorimore, Jeroen C F Verhaegen, Moritz Innmann, A Paul Monk, Christopher Ling, George Grammatopoulos
BACKGROUND AND PURPOSE: Arthroplasty surgeons traditionally assess cup orientation after total hip arthroplasty (THA) on supine radiographs. Contemporary hip-spine analyses provide information on standing, functional cup orientation. This study aims to (i) characterize cup orientations when supine and standing; (ii) determine orientation differences between postures; and (iii) identify factors associated with magnitude of orientation differences. METHODS: This is a 2-center, multi-surgeon, prospective, consecutive cohort study...
July 22, 2024: Acta Orthopaedica
Wilco Peul, Frank Kandziora
No abstract text is available yet for this article.
2024: Brain Spine
Matthew Dulas, Thomas J Utset-Ward, Jason A Strelzow, Tessa Balach
INTRODUCTION: The Accreditation Council for Graduate Medical Education Resident Case Log is one of the primary tools used to track surgical experience. Owing to the self-reported nature of case logging, there is uncertainty in the consistency and accuracy of case logging. The aims of this study are two-fold: to assess current resident case log Current Procedural Terminology (CPT) code selection and practices across orthopaedic surgery residencies and to understand current attitudes of both program directors (PD) and residents surrounding case logging...
2024: JB & JS Open Access
Joon Ho Choi, Jin-Sook Ryu
No abstract text is available yet for this article.
August 2024: Nuclear Medicine and Molecular Imaging
David R Woodard, Jarod A Richards, Kelsey Knake, Steven DeFroda
Hip arthroscopy has been on the rise since its inception. Initial descriptions of the procedure required skeletal traction of the operative extremity with countertraction provided by a perineal post. Perineal posts are associated with complications such as perineal nerve palsy, genital laceration, and hematoma formation. Postless traction has been developed to avoid complications related to use of perineal posts. A patient is positioned supine on a postless traction table (Guardian; Stryker, Greenwood Village, CO) with a disposable traction pad...
June 2024: Arthroscopy Techniques
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