keyword
https://read.qxmd.com/read/38696675/dual-energy-for-pulmonary-vein-isolation-using-dual-energy-focal-ablation-technology-integrated-with-a-three-dimensional-mapping-system-smartfire-3-month-results
#1
MULTICENTER STUDY
Mattias Duytschaever, Gediminas Račkauskas, Tom De Potter, Jim Hansen, Sebastian Knecht, Thomas Phlips, Johan Vijgen, Daniel Scherr, Gabor Szeplaki, Hugo Van Herendael, Mads Brix Kronborg, Benjamin Berte, Helmut Pürerfellner, Peter Lukac
AIMS: Contact force (CF)-sensing radiofrequency (RF) catheters with an ablation index have shown reproducible outcomes for the treatment of atrial fibrillation (AF) in large multicentre studies. A dual-energy (DE) focal CF catheter to deliver RF and unipolar/biphasic pulsed field ablation (PFA), integrated with a three-dimensional (3D) mapping system, can provide operators with additional flexibility. The SmartfIRE study assessed the safety and efficacy of this novel technology for the treatment of drug-refractory, symptomatic paroxysmal AF...
May 2, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/38696013/a-green-and-economic-approach-to-synthesize-magnetic-lagenaria-siceraria-biochar-%C3%AE-fe-2-o-3-lsb-for-methylene-blue-removal-from-aqueous-solution
#2
JOURNAL ARTICLE
Ayushi Mishra, Jyoti Pandey, Himanshu Ojha, Malti Sharma, Lajpreet Kaur, Akhilesh Pandey, Pankaj Sharma, Sumit Murab, Rahul Singhal, Mallika Pathak
In the printing and textile industries, methylene blue (a cationic azo dye) is commonly used. MB is a well-known carcinogen, and another major issue is its high content in industrial discharge. There are numerous removal methodologies that have been employed to remove it from industrial discharge; however, these current modalities have one or more limitations. In this research, a novel magnetized biochar (γ-Fe2 O3 -LSB) was synthesized using Lagenaria siceraria peels which were further magnetized via the co-precipitation method...
May 2, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38695462/perinatal-mortality-severe-maternal-morbidity-and-maternal-near-miss-protocol-of-a-study-integrated-with-the-birth-in-brazil-ii-survey
#3
JOURNAL ARTICLE
Rosa Maria Soares Madeira Domingues, Marcos Augusto Bastos Dias, Marcos Nakamura-Pereira, Rodolfo de Carvalho Pacagnella, Sônia Lansky, Silvana Granado Nogueira da Gama, Ana Paula Esteves-Pereira, Sônia Azevedo Bittencourt, Mariza Miranda Theme Filha, Barbara Vasques da Silva Ayres, Márcia Leonardi Baldisserotto, Tatiana Henriques Leite, Maria do Carmo Leal
Brazil presents high maternal and perinatal morbidity and mortality. Cases of severe maternal morbidity, maternal near miss, and perinatal deaths are important health indicators and share the same determinants, being closely related to living conditions and quality of perinatal care. This article aims to present the study protocol to estimate the perinatal mortality rate and the incidence of severe maternal morbidity and maternal near miss in the country, identifying its determinants. Cross-sectional study integrated into the research Birth in Brazil II, conducted from 2021 to 2023...
2024: Cadernos de Saúde Pública
https://read.qxmd.com/read/38694775/baseline-characteristics-and-outcome-of-stroke-patients-after-endovascular-therapy-according-to-previous-symptomatic-vascular-disease-and-sex
#4
JOURNAL ARTICLE
Marieta Peycheva, Giovanna Padlina, Kotryna Genceviciute, Marina P Krasteva, Anna Boronylo, Martina B Goeldlin, Madlaine Müller, Elena S Wenz, Mandy D Müller, Helly Hammer, Philipp Bücke, Sandra Bigi, Barbara Goeggel Simonetti, Angelika Hoffmann, Roza M Umarova, Sara Pilgram-Pastor, Jan Gralla, Pasquale Mordasini, Kateryna Antonenko, Mirjam R Heldner
AIM: The aim of this study was to investigate baseline characteristics and outcome of patients after endovascular therapy (EVT) for acute large vessel occlusion (LVO) in relation to their history of symptomatic vascular disease and sex. METHODS: Consecutive EVT-eligible patients with LVO in the anterior circulation admitted to our stroke center between 04/2015 and 04/2020 were included in this observational cohort study. All patients were treated according to a standardized acute ischaemic stroke (AIS) protocol...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38692732/novel-point-of-care-cytokine-biomarker-lateral-flow-test-for-the-screening-for-sexually-transmitted-infections-and-bacterial-vaginosis-study-protocol-of-a-multicentre-multidisciplinary-prospective-observational-clinical-study-to-evaluate-the-performance-and
#5
MULTICENTER STUDY
Stephanie Ramboarina, Tania Crucitti, Katherine Gill, Linda Gail Bekker, Emma Michele Harding-Esch, Janneke H H M van de Wijgert, Bich-Tram Huynh, Camille Fortas, Aina Harimanana, Théodora Mayouya Gamana, Rindra Vatosoa Randremanana, Reziky Mangahasimbola, Chido Dziva Chikwari, Katharina Kranzer, Constance R S Mackworth-Young, Sarah Bernays, Nicola Thomas, David Anderson, Fatime Ramla Tanko, Monalisa Manhanzva, Micaela Lurie, Fezile Khumalo, Edina Sinanovic, Ayako Honda, Tanya Pidwell, Suzanna C Francis, Lindi Masson, Jo-Anne Passmore
INTRODUCTION: A prototype lateral flow device detecting cytokine biomarkers interleukin (IL)-1α and IL-1β has been developed as a point-of-care test-called the Genital InFlammation Test (GIFT)-for detecting genital inflammation associated with sexually transmitted infections (STIs) and/or bacterial vaginosis (BV) in women. In this paper, we describe the rationale and design for studies that will be conducted in South Africa, Zimbabwe and Madagascar to evaluate the performance of GIFT and how it could be integrated into routine care...
May 1, 2024: BMJ Open
https://read.qxmd.com/read/38689440/fatigue-alleviation-by-low-level-laser-pre-exposure-in-ischemic-neuromuscular-electrical-stimulation
#6
JOURNAL ARTICLE
Chia-Chan Wu, Yen-Ting Lin, Chia-Ling Hu, Yi-Ching Chen, Ing-Shiou Hwang
PURPOSE: Despite its susceptibility to muscle fatigue, combined neuromuscular electrical stimulation (NMES) and blood flow restriction (BFR) is an effective regimen for managing muscle atrophy when traditional resistance exercises are not feasible. This study investigated the potential of low-level laser therapy (LLLT) in reducing muscle fatigue after the application of combined NMES and BFR. METHODS: Thirty-six healthy adults were divided into control and LLLT groups...
May 1, 2024: Medicine and Science in Sports and Exercise
https://read.qxmd.com/read/38687759/effect-of-low-intensity-focused-ultrasound-therapy-on-postpartum-uterine-involution-in-puerperal-women-a-randomized-controlled-trial
#7
RANDOMIZED CONTROLLED TRIAL
Dongmei Wei, Zhijian Wang, Jun Yue, Yueyue Chen, Jian Meng, Xiaoyu Niu
BACKGROUND: Short-term poor uterine involution manifests as uterine contraction weakness. This is one of the important causes of postpartum hemorrhage, posing a serious threat to the mother's life and safety. The study aims to investigate whether low-intensity focused ultrasound (LIFUS) can effectively shorten lochia duration, alleviate postpartum complications, and accelerate uterine involution compared with the sham treatment. METHODS: A multicenter, concealed, randomized, blinded, and sham-controlled clinical trial was conducted across three medical centers involving 176 subjects, utilizing a parallel group design...
2024: PloS One
https://read.qxmd.com/read/38687693/a-multidisciplinary-approach-to-improve-adherence-to-medical-recommendations-in-older-adults-at-hospital-discharge-the-approach-study-protocol
#8
RANDOMIZED CONTROLLED TRIAL
Bruno Micael Zanforlini, Sara Sambo, Maria Devita, Andrea Cignarella, Federico Vezzali, Silvia Sturani, Andrea Grandieri, Marianna Noale, Paola Siviero, Federica Limongi, Stefano Volpato, Giuseppe Sergi, Caterina Trevisan
INTRODUCTION: Poor comprehension and medication adherence are common in older people, especially after hospitalizations, in case of changes or prescriptions of new therapeutic regimes. This randomized controlled trial aims to evaluate the effectiveness of an integrated approach in improving older individuals' adherence to medical recommendations after hospital discharge. METHODS: Data from an expected sample of 360 older inpatients (and their caregivers) will be collected...
2024: PloS One
https://read.qxmd.com/read/38686809/standardizing-process-in-acute-biliary-disease
#9
JOURNAL ARTICLE
Isaac Tranter-Entwistle, Tim Eglinton, Saxon Connor
INTRODUCTION: The perioperative management of biliary disease (BD) is variable across institutions with suboptimal outcomes for patients and health care systems. This results in inefficient utilization of limited resources. The aim of the current study was to identify modifiable factors impacting patients' time to theater, intraoperative time, and time to discharge as the constituents of length of stay to guide creation of a perioperative management protocol to address this variability...
February 2024: World Journal of Surgery
https://read.qxmd.com/read/38686771/outcomes-of-a-same-day-discharge-protocol-in-patients-undergoing-mastectomy-and-implant-reconstruction
#10
JOURNAL ARTICLE
Danielle S Hayes, Wandra K Miles, Monica Solorio, Suzette G Miranda
BACKGROUND: Finite hospital resources has required a closer look at resource allocation. This has prompted a shift toward same day surgeries and a focus on reducing hospital readmissions. Following the institution of a same day discharge protocol for mastectomy and mastectomy with immediate reconstruction, we sought to assess differences in the length of stay and readmission rates. METHODS: This retrospective review evaluates all cases of mastectomy with or without immediate reconstruction performed at a single high-volume center between June 2019 and March 2021...
January 2024: World Journal of Surgery
https://read.qxmd.com/read/38686766/enhanced-recovery-after-surgery-after-radical-gastrectomy-improved-compliance-over-time-is-associated-with-a-shorter-postoperative-hospital-stay
#11
JOURNAL ARTICLE
James Tankel, Anitha Kammili, Andrew Meng, Mehrnoush Dehghani, Rawan Sakalla, Jonathan Spicer, Sara Najmeh, Jonathan Cools-Lartigue, Lorenzo Ferri, Carmen Mueller
BACKGROUND: Changing adherence over time to enhanced recovery after surgery (ERAS) protocols following radical gastrectomy and the impact this has on length of stay (LoS) is not well described. This study aimed to explore the changes in adherence to core ERAS elements over time and the relationship between compliance and LoS. METHODS: A retrospective, single center cohort study was performed between 01/2016-12/2021. An ad hoc analysis revealed the point at which a significant difference in the number of patients being discharge on postoperative day (PoD) 3 was noted allowing allocation of patients to Group A (01/2016-12/2019) or B (01/2020-12/2021)...
February 2024: World Journal of Surgery
https://read.qxmd.com/read/38685147/antibiotic-prophylaxis-in-alloplastic-temporomandibular-joint-replacement-surgery-a-multi-national-survey-of-temporomandibular-joint-surgeons
#12
JOURNAL ARTICLE
B Es Dawoud, T Hampson, R Barrow, L G Mercuri
Temporomandibular disorders include a wide spectrum of extra-articular and intra-articular conditions affecting the temporomandibular joint (TMJ). In salvage cases involving intra-articular end-stage disease, alloplastic temporomandibular joint replacement (TMJR) is a management option which can be utilised to rehabilitate a disabled joint's function and form. Whilst post-TMJR infection is rare, it is one of the most serious complications. The principles governing TMJR surgery antibiotic prophylaxis have been based on those established in orthopaedic surgery literature...
March 24, 2024: British Journal of Oral & Maxillofacial Surgery
https://read.qxmd.com/read/38685032/hypotension-prediction-index-guided-goal-directed-therapy-to-reduce-postoperative-acute-kidney-injury-during-major-abdominal-surgery-study-protocol-for-a-multicenter-randomized-controlled-clinical-trial
#13
JOURNAL ARTICLE
Javier Ripollés-Melchor, Laura Carrasco-Sánchez, José L Tomé-Roca, César Aldecoa, Andres Zorrilla-Vaca, Juan V Lorente-Olazábal, María J Colomina, Ana Pérez, Juan I Jiménez-López, Rosalía Navarro-Pérez, Alfredo Abad-Gurumeta, Manuel I Monge-García
BACKGROUND: Acute kidney injury (AKI) is a significant postoperative complication associated with increased mortality and hospital costs. Hemodynamic strategies, such as goal-directed therapy, might reduce AKI risk. Predicting and proactively managing intraoperative hypotension may be helpful. This trial aims to investigate if a preemptive hemodynamic strategy guided by the hypotension prediction index (HPI) can decrease the incidence of moderate-to-severe AKI within 30 days following major elective abdominal surgery...
April 29, 2024: Trials
https://read.qxmd.com/read/38684595/collaborative-recognition-of-wellbeing-needs-a-novel-approach-to-universal-psychosocial-screening-on-the-neonatal-unit
#14
JOURNAL ARTICLE
Davy Evans, Daisy Eatwell, Shevonne Hodson-Walker, Sarah Pearce, Vicky Reynolds, Shona Smith, Leah Whitehouse, Ruth Butterworth
Universal screening for the psychological needs of families in neonatal care is internationally recommended, but is not routinely practiced in the United Kingdom (UK). The present quality improvement project explores the clinical and operational feasibility of a novel approach to universal screening on a neonatal intensive care unit in the UK. The approach to screening taken adopts collaborative, strengths-based and dialogical methods for recognising the psychological needs of families whose baby is in hospital...
April 29, 2024: Journal of Clinical Psychology in Medical Settings
https://read.qxmd.com/read/38681999/an-emergency-department-based-system-intervention-to-improve-osteoporosis-screening-for-older-adults-at-high-risk-of-fracture
#15
JOURNAL ARTICLE
Lesley E Jackson, Rachel M Skains, Amy Mudano, Norma Techarukpong, James S Booth, Kenneth G Saag, Liana Fraenkel, Maria I Danila
Falls and osteoporosis are risk factors for fragility fractures. Bone mineral density (BMD) assessment is associated with better preventative osteoporosis care, but it is underutilized by those at high fracture risk. We created a novel electronic medical record (EMR) alert-driven protocol to screen patients in the Emergency Department (ED) for fracture risk and tested its feasibility and effectiveness in generating and completing referrals for outpatient BMD testing after discharge. The EMR alert was configured in 2 tertiary-care EDs and triggered by the term "fall" in the chief complaint, age (≥65 years for women, ≥70 years for men), and high fall risk (Morse score ≥ 45)...
May 2024: JBMR Plus
https://read.qxmd.com/read/38674897/proactive-use-of-a-human-milk-fat-modular-in-the-neonatal-intensive-care-unit-a-standardized-feeding-protocol
#16
JOURNAL ARTICLE
Amanda Salley, Martin L Lee
UNLABELLED: An exclusive human milk diet (EHMD) and standardized feeding protocols are two critical methods for safely feeding very low birth weight (VLBW) infants. Our institution initiated a standardized feeding protocol for all VLBW infants in 2018. In this protocol, a human milk fat modular was used only reactively when an infant had poor weight gain, fluid restriction, or hypoglycemia. As part of our NICU quality improvement program, internal utilization review data revealed a potential opportunity to improve growth and reduce costs...
April 18, 2024: Nutrients
https://read.qxmd.com/read/38674270/time-is-life-golden-ten-minutes-on-scene-eureca_serbia-2014-2023
#17
JOURNAL ARTICLE
Suzana Randjelovic, Srdjan Nikolovski, Dragica Selakovic, Miodrag Sreckovic, Sara Rosic, Gvozden Rosic, Violetta Raffay
Background and Objectives : This study analyzed the frequency of factors influencing the course and outcomes of out-of-hospital cardiac arrest (OHCA) in Serbia and the prediction of pre-hospital outcomes and survival. Materials and Methods : Data were collected during the period from 1 October 2014, to 31 September 2023, according to the protocol of the EuReCa_One study (clinical trial ID number NCT02236819). Results : Overall 9303 OHCA events were registered with a median age of 71 (IQR 61-81) years and 59...
April 11, 2024: Medicina
https://read.qxmd.com/read/38672715/confronting-a-new-challenge-in-plastic-surgery-mdr-infections-in-patients-with-chronic-wounds
#18
JOURNAL ARTICLE
Laura Răducu, Oriana Elena Moraru, Daniela-Elena Gheoca-Mutu, Teodora Peligrad, Andrada-Elena Țigăran, Abdalah Abu-Baker, Daniela-Elena Ion, Bogdan Mihai Ursuț, Cristian-Radu Jecan, Adelaida Avino
BACKGROUND: The presence of a wound can be anywhere from non-problematic to life-threatening on a severity spectrum, with bacterial infection and resistance playing a major role in the development of chronicity, delaying wound healing. Wound colonization with multiple organisms and the limited number of effective antibiotics place a heavy burden on the healthcare system, with patients going through multiple surgeries during a prolonged hospitalization time. By analyzing the resistance patterns of pluri-bacterial populations and the approach used in managing complex cases, we aim to improve the protocols applied in caring for chronic wounds in our practice and share our experiences and observations...
March 27, 2024: Life
https://read.qxmd.com/read/38671673/premature-babies-can-be-cared-for-in-the-maternity-ward-without-an-increased-risk-and-discharged-with-a-feeding-tube-if-necessary
#19
JOURNAL ARTICLE
Lea Rösch, Edda Hofstätter, Franziska Krasnitzer-Leitner, Martin Wald
In general, premature babies are discharged home when they reach full self-feeding. We established a discharge management protocol which allows for discharging late preterm babies with a feeding tube if necessary. This retrospective study included 108 preterm infants (34+ weeks) born in 2019 and 2020. The preterm infants discharged with a feeding tube ( n = 32) were born at 35.23 weeks' gestation (±0.884), with a birth weight of 2423 g (±375.1), and were discharged at 7.22 days (±3.63) and had a weight of 3466 g (±591...
April 10, 2024: Children
https://read.qxmd.com/read/38670603/outcome-predictors-and-longitudinal-trajectories-of-subjects-with-critical-illness-polyneuropathy-and-myopathy-cinamops-study-protocol-of-an-observational-cohort-study-in-a-clinical-and-post-clinical-setting
#20
JOURNAL ARTICLE
Jeannine Bergmann, Marion Egger, Friedemann Müller, Klaus Jahn
INTRODUCTION: Critical illness polyneuropathy and myopathy (CIP/CIM) are frequent complications in the intensive care unit (ICU) with major consequences for the progress and outcome of subjects. CIP/CIM delays the weaning process, prolongs the hospital stay and increases the mortality rate. Additionally, it may have long-term consequences beyond the hospitalisation phase with prolonged disability. Even though there is growing interest in CIP/CIM, research about the clinical and post-clinical course as well as the middle-term and long-term outcomes of subjects with CIP/CIM is scarce...
April 25, 2024: BMJ Open
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