Xuan-Hai Do, My Hanh Thi Hoang, Anh-Tuan Vu, Lai-Thanh Nguyen, Dung Thi Thuy Bui, Duy-Thanh Dinh, Xuan-Hung Nguyen, Uyen Thi Trang Than, Hien Thi Mai, Thuy Thanh To, Tra Ngoc Huong Nguyen, Nhung Thi My Hoang
Although curcumin in the form of nanoparticles has been demonstrated as a potential anti-tumor compound, the impact of curcumin and nanocurcumin in vitro on normal cells and in vivo in animal models is largely unknown. This study evaluated the toxicity of curcumin-loaded micelles in vitro and in vivo on several tumor cell lines, primary stromal cells, and zebrafish embryos. Breast tumor cell line (MCF7) and stromal cells (human umbilical cord vein endothelial cells, human fibroblasts, and human umbilical cord-derived mesenchymal stem cells) were used in this study...
October 15, 2022: International Journal of Molecular Sciences