Bayushi Eka Putra, Suko Adiarto, Santi Rahayu Dewayanti, Dafsah Arifa Juzar
Cutaneous manifestation is a newly reported clinical manifestation of COVID-19 infection. The clinical description of cutaneous manifestation is still not fully described. Our patient, a medical personnel, had viral exanthem distributed in the extremities along with "pin and needles sensation" which differ from the previously published paper on cutaneous manifestation. The differential diagnosis of drug-induced skin rash and hand-foot-mouth disease have already been ruled out based on the patient's previous history and course of disease...
May 8, 2020: International Journal of Infectious Diseases: IJID
C-J Su, C-H Lee
No abstract text is available yet for this article.
June 2020: Journal of the European Academy of Dermatology and Venereology: JEADV
Janna M Vassantachart, Anthony H Yeo, Andrew Y Vassantachart, Sharon E Jacob, Linda Golkar
Measles is a viral infection that has a characteristic pattern of prodromal symptoms followed by a rash. Previously considered an inevitable childhood condition, measles is known as the "first" classic childhood exanthem. For most children, measles was a one-time, short-term illness; however, some children developed complications that led to severe sequelae and death. The introduction of the measles vaccine dramatically decreased the number of cases, but the current trend against vaccination has caused outbreaks of the condition...
March 2020: International Journal of Women's Dermatology
Emman Dabaja, Rabah Daoud, Obadah Alquadan, Jocelyn Y Ang
No abstract text is available yet for this article.
April 4, 2020: Clinical Pediatrics
Sudipta R Chowdhury, Dawn Lee
No abstract text is available yet for this article.
May 2020: Journal of Paediatrics and Child Health
Dharshini Sathishkumar, Parthiban Udhayakumar, Debasis Das Adhikari, Renu George
Background: Skin problems are commonly encountered in the pediatric emergency department (PED). Although there are a few studies on the prevalence and spectrum of skin conditions in children attending the PED, only limited information is available on the outcome of the children with skin-related ailments requiring hospitalization. Aim: To study the clinical profile of skin manifestations in children presenting to the PED over a period of one year and assess the impact of skin lesions on the clinical outcome...
November 2019: Indian Dermatology Online Journal
Sung Shin Teng, Cheng Rong Chua, Yiong Huak Chan, Gene Yong-Kwang Ong
BACKGROUND: Viral exanthems in the pediatric age group are common. The worldwide increase in the incidence of highly infectious measles and other vaccine-preventable diseases and its impact in emergency departments (EDs) of a cosmopolitan city-state like Singapore are unknown. Our aims were to investigate and describe recent epidemiologic trends of proven measles infection seen in our ED and elucidate risk factors that can potentially impact our ED isolation practice. METHODS: This is a retrospective observational cohort study on laboratory-confirmed measles infection in patients admitted through our pediatric ED from January 2010 to December 2016...
December 2019: Pediatric Infectious Disease Journal
Vincent C C Cheng, Shuk-Ching Wong, Sally C Y Wong, Siddharth Sridhar, Jonathan H K Chen, Cyril C Y Yip, Derek L L Hung, Xin Li, Vivien W M Chuang, Owen T Y Tsang, Gibson K S Woo, Shuk-Kwan Chuang, Kwok-Yung Yuen
OBJECTIVE: To report an outbreak of measles with epidemiological link between Hong Kong International Airport (HKIA) and a hospital. METHODS: Epidemiological investigations, patients' measles serology, and phylogenetic analysis of the hemagglutinin (H) and nucleoprotein (N) genes of measles virus isolates were conducted. RESULTS: In total, 29 HKIA staff of diverse ranks and working locations were infected with measles within 1 month. Significantly fewer affected staff had history of travel than non-HKIA-related measles patients [10 of 29 (34...
October 7, 2019: Infection Control and Hospital Epidemiology
Nicole Knöpfel, Lucero Noguera-Morel, Irene Latour, Antonio Torrelo
Viral exanthems are frequent in children and are mostly self-limited. Early recognition and differentiation from other childhood illnesses are important to direct further investigations and treatment initiation. The clinical presentation of viral exanthems in children includes a polymorphic spectrum of skin eruptions ranging from classic viral exanthems to "atypical" presentations that can mimic nonviral diseases; thus, viral exanthems of childhood can be readily diagnosed on clinical grounds, but not rarely do they represent a diagnostic challenge...
May 2019: Clinics in Dermatology
Bochao Wang, Mitsuhiro Nishimura, Yuji Maekawa, Toshiya Kotari, Toshiomi Okuno, Yasuko Mori
Exanthem subitum is a common childhood illness caused by Human herpesvirus 6B (HHV-6B) primary infection. It is occasionally complicated by febrile seizure and even encephalitis. The HHV-6B reactivation also causes encephalitis especially after allogeneic hematopoietic stem cell transplantation. However, no adequate antiviral treatment for HHV-6B has yet been established. Mouse-derived monoclonal antibodies (Mabs) against the envelope glycoprotein complex gH/gL/gQ1/gQ2 of HHV-6B have been shown to neutralize the viral infection...
March 6, 2019: Journal of Virology
Masahiro Oka, Takeshi Fukumoto, Nobuo Ohta, Takeshi Kozaru
No abstract text is available yet for this article.
February 8, 2019: European Journal of Dermatology: EJD
Amaran Moodley, Jack Swanson, Charles Grose, Daniel J Bonthius
Varicella vaccination is now virtually universal in North America, as well as in some European and Asian countries. Since varicella vaccine is a live attenuated virus, the virus replicates in the skin after administration and can travel via sensory nerves or viremia to become latent in the dorsal root ganglia. In some immunized children, virus reactivates within a few months to a few years to cause the dermatomal exanthem known as herpes zoster (shingles). Herpes zoster caused by vaccine virus often reactivates within the same dermatome as the site of the original varicella vaccine injection...
March 2019: Journal of Child Neurology
F Broccolo, F Drago, G Ciccarese, A Genoni, A Puggioni, G M Rosa, A Parodi, H Manukyan, M Laassri, K Chumakov, A Toniolo
BACKGROUND: Typically, hand-foot-and-mouth disease (HFMD) is a mild childhood illness associated with coxsackievirus (CV)-A16, CV-A6, enterovirus (EV)-A71. OBJECTIVES: To identify the viral agents associated with severe cases of atypical HFMD in Italy. STUDY DESIGN: Epidemiologically unrelated cases of severe atypical HFMD admitted to the Emergency Room (ER) of IRCCS San Martino IST (Genoa, Italy) in 2014-2016 were investigated. Serologic screening for viral positivity was performed against exanthem-inducing agents...
January 2019: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
Almut Böer-Auer, Dieter Metze
BACKGROUND: Hand-foot-mouth disease (HFMD) is a common contagious viral infection usually affecting infants and children. Recently, literature on HFMD in adults is increasing. It has been reported that adults often present with unusual exanthems with similarities to erythema multiforme (EM). No study has so far compared the histologic features of HFMD with those of EM. METHODS: Histopathologic features in 7 biopsies of 6 adult patients with HFMD are compared with biopsies from 9 patients with EM to identify the best criteria for differentiation...
April 2019: American Journal of Dermatopathology
Rui Arrais de Castro, Paula Vilas, João Borges-Costa, Rui Tato Marinho
There are rare reports of association between hepatitis C virus (HCV) infection and dermatomyositis although cause and effect remains to be proven. We present a clinical case with a probable cause and effect association between these two entities. A 71-year-old woman developed an erythematous exanthem with pruritic and scaly lesions located at the torso and upper limbs associated with heliotrope and Gottron's papules. At the same time, she notice a significant loss of muscular strength. Skin and muscular biopsies made the diagnosis of dermatomyositis and the patient started with prednisolone (60 mg/day) with poor symptoms control...
July 25, 2018: BMJ Case Reports
Monica Rosales Santillan, Jessica B Dietert, Richard Jahan-Tigh
Papular purpuric gloves and socks syndrome (PPGSS) is a self-limited exanthem that presents as painful or pruritic edema, erythema, petechiae, and purpura of the palms and soles with occasional extension to the dorsal hands and feet. The majority of PPGSS cases reported in the literature are associated with parvovirus B19 and occur in children and young adults. In a recent literature search, there were 11 PPGSS cases in adults with none reporting Epstein-Barr virus (EBV) as a viral etiology. However, there have been PPGSS cases related to EBV in children...
April 15, 2018: Dermatology Online Journal
Howard D Lee, Samuel Butterfield, Joseph Maddry, Douglas Powell, William N Vasios, Heather Yun, David Ferraro, Jeremy C Pamplin
Review clinical thought process and key principles for diagnosing weaponized chemical and biologic injuries. Clinical Context: Special Operation Forces (SOF) team deployed in an undisclosed, austere environment. Organic Expertise: Two SOF Soldiers with civilian EMT-Basic certification. Closest Medical Support: Mobile Forward Surgical Team (2 hours away); medical consults available by e-mail, phone, or video-teleconsultation. Earliest Evacuation: Earliest military evacuation from country 12-24 hours. With teleconsultation, patients departed to Germany as originally scheduled without need for Medical Evacuation...
December 0: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
Jose M Villalon-Gomez
Pityriasis rosea is a common self-limiting rash that usually starts with a herald patch on the trunk and progresses along the Langer lines to a generalized rash over the trunk and limbs. The diagnosis is based on clinical and physical examination findings. The herald patch is an erythematous lesion with an elevated border and depressed center. The generalized rash usually presents two weeks after the herald patch. Patients can develop general malaise, fatigue, nausea, headaches, joint pain, enlarged lymph nodes, fever, and sore throat before or during the course of the rash...
January 1, 2018: American Family Physician
Dimple Chopra, Aastha Sharma, Satwinder Kaur, Ravinder Singh
Eruptive pseudoangiomatosis is a rare viral exanthem characterized by acute onset of hemangiomata-like lesions, however, histological findings are distinct from that of true angiomas. This entity has been reported from Europe, North America, Japan, and Korea till date. Here, we report 12 cases of eruptive pseudoangiomatosis from a tertiary care hospital in Punjab.
July 2018: Indian Journal of Dermatology, Venereology and Leprology
Carlos A Arango, Ross Jones
Some share features, making them difficult to distinguish. Others may not be on your radar. Here we review 8 you're likely to see or need to exclude.
October 2017: Journal of Family Practice
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