keyword
https://read.qxmd.com/read/38524347/ocular-nodular-fasciitis-in-kawasaki-disease
#1
JOURNAL ARTICLE
Sashwanthi Mohan, Madhuvanthi Mohan, Sujatha Mohan
No abstract text is available yet for this article.
2024: Oman Journal of Ophthalmology
https://read.qxmd.com/read/38505139/intra-articular-nodular-fasciitis-of-the-knee-a-rare-clinical-presentation-and-histological-diagnosis-a-case-report
#2
JOURNAL ARTICLE
Neil P Buac, Linus Lee, Gayathri Vijayakumar, Charles Gusho, Alan T Blank
INTRODUCTION: Nodular fasciitis is a rare, benign soft tissue lesion that can prove to be difficult to diagnose, especially when intra-articular. CASE PRESENTATION: A 17-year-old female softball player presents with several year history of right knee pain and swelling initially attributed to patellar maltracking refractory to non-operative and operative management. MANAGEMENT AND OUTCOMES: Initial pathology suggested tenosynovial giant cell tumor; however, further tissue diagnosis revealed nodular fasciitis, which was eventually resected...
2024: Orthopedic Reviews
https://read.qxmd.com/read/38503969/utility-of-lef1-to-differentiate-desmoid-fibromatosis-from-its-histologic-mimics
#3
JOURNAL ARTICLE
Soma Jobbagy, Santiago Lozano-Calderon, John T Mullen, G Petur Nielsen, Yin P Hung, Ivan Chebib
Diagnosis of desmoid-type fibromatosis (DF) may be challenging on biopsy due to morphologic overlap with reactive fibrosis (scar) and other uniform spindle cell neoplasms. Evaluation of nuclear β-catenin, a surrogate of Wnt pathway activation, is often difficult in DF due to weak nuclear expression and high background membranous/cytoplasmic staining. Lymphoid enhancer-factor 1 (LEF1) is a recently characterized effector partner of β-catenin which activates the transcription of target genes. We investigated the performance of LEF1 and β-catenin immunohistochemistry in a retrospective series of 156 soft tissue tumors, including 35 DF, 3 superficial fibromatosis, and 121 histologic mimics (19 soft tissue perineurioma, 8 colorectal perineurioma, 4 intraneural perineurioma, 26 scars, 23 nodular fasciitis, 6 low-grade fibromyxoid sarcomas, 6 angioleiomyomas, 5 neurofibromas, 5 dermatofibrosarcoma protuberans, 3 low-grade myofibroblastic sarcomas, 3 synovial sarcomas, 3 inflammatory myofibroblastic tumors, 2 schwannomas, and 1 each of Gardner-associated fibroma, radiation-associated spindle cell sarcoma, sclerotic fibroma, dermatofibroma, and glomus tumor)...
March 19, 2024: Virchows Archiv: An International Journal of Pathology
https://read.qxmd.com/read/38470264/-a-hard-subcutaneous-swelling-not-always-as-malignant-as-it-seems
#4
JOURNAL ARTICLE
Jade G M Logger, Ellen H C J Liberton, Rob J C Vogels, Sander van der Wolk
BACKGROUND: Nodular fasciitis is a rare, benign soft tissue tumor in young adults on the arms or trunk. CASE DESCRIPTION: A 24-year-old woman with previous pretibial melanoma in situ presented with a painless, rapidly growing subcutaneous hard swelling on the right forearm since two weeks. Ultrasound showed a subcutaneous, irregularly shaped, vascularized mass, suspicious for malignancy. Three days later, the swelling had subsided spontaneously. A new ultrasound showed a smaller, oval, sharply demarcated lesion with an inflammatory aspect...
March 5, 2024: Nederlands Tijdschrift Voor Geneeskunde
https://read.qxmd.com/read/38433051/-clinical-imaging-and-pathological-and-molecular-characteristics-of-simple-bone-cyst
#5
JOURNAL ARTICLE
X X Yang, S J Sheng, Y F Zou, Y Zhu, Y Ding, Q H Fan, Q X Gong
Objective: To investigate the radiologic, pathologic, and molecular features of simple bone cysts (SBC), and their differential diagnoses. Methods: Fourteen cases of SBC were collected at the Department of Pathology, the First Affiliated Hospital of Nanjing Medical University from 2017 to 2022, and fluorescence in situ hybridization (FISH) was performed for retrospective analysis. Results: There were 14 patients, including 7 females and 7 males, with age range of 7 to 45 (median 29) years. The most common complaint was pain, including 4 cases with pathological fracture and 5 with history of previous trauma...
March 8, 2024: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://read.qxmd.com/read/38405650/oral-nodular-fasciitis-a-case-report-in-an-uncommon-location-and-review-of-the-literature
#6
Maha T Alsharif, Asma Alzahrani, Hattan Zaki, Alaa F Bukhari, Ahoud Jazzar
Nodular fasciitis (NF) is a benign, self-limiting condition that is often misdiagnosed due to its resemblance to other lesions. Although NF is common, its occurrence in the oral cavity is rare and particularly challenging for both clinicians and pathologists. To date, no case has been reported in the retromolar area of the oral cavity.   A 49-year-old male patient presented with a painless, rapidly growing, firm nodule in the right retromolar area. Histopathological examination revealed spindle cell proliferation with characteristics of NF and immunohistochemical analysis confirmed the diagnosis...
February 2024: Curēus
https://read.qxmd.com/read/38391362/ischemic-fasciitis-scalp-unusual-presentation-and-location
#7
JOURNAL ARTICLE
Preeti J John, Richa Mahajan, Kanwardeep Singh Kwatra, Savreet Pal Singh
We report a case of ischemic fasciitis in a 34-year-old male patient who presented with hard swelling on the anterior aspect of the scalp measuring 5 × 4 cm. He gave a history of wearing a tight turban constantly for many years. The lesion initially presented as redness of the skin, which gradually became a nodular swelling over 2 years. A computed tomography (CT) scan showed conical solid soft tissue attenuation mass. The operative findings were suspicious of neoplasm. However, the microscopic findings were typical of ischemic fasciitis, that is, a zonal pattern with central hypocellular fibrinoid necrosis surrounded by more cellular areas containing prominent proliferating neovessels and fibroblasts resembling granulation tissue...
July 26, 2023: Indian Journal of Pathology & Microbiology
https://read.qxmd.com/read/38372608/-a-clinical-case-of-piloleiomyoma
#8
JOURNAL ARTICLE
N S Alekseeva, A A Ivina, A G Nadtochiy, I I Babichenko
The article describes a clinical case of a benign tumor from smooth muscle cells - piloleiomyoma. The incidence of leiomyoma in the skin is 3-5% of all leiomyomas. A 27-year-old patient applied to a medical institution with complaints about an intradermal formation in the ear region that occurred repeatedly within 5 months after surgical treatment. After the first surgical intervention, the patient was consulted in various medical organizations, where the following diagnoses were made: «nodular fasciitis», «smooth muscle tumor without signs of malignancy» and «non-epithelial spindle cell neoplasm»...
2024: Stomatologii︠a︡
https://read.qxmd.com/read/38363417/pathology-of-intra-articular-tumours-and-tumour-like-lesions-pearls-pitfalls-and-rarities-from-a-general-surgical-pathology-practice
#9
REVIEW
Alison L Cheah, Wendy Brown, S Fiona Bonar
Intra-articular tumours are uncommonly encountered in routine practice and may present diagnostic challenges to pathologists. Challenges unique to this site include distinction from more common reactive synovial conditions, which are far more common; histologic variability; superimposed reactive changes; and often, lack of provided clinicoradiological context. This article reviews the pathology of the synovial tumours and tumour-like lesions, including diagnostic pearls, pitfalls and rare entities.
February 16, 2024: Skeletal Radiology
https://read.qxmd.com/read/38322357/nodular-fasciitis-of-the-orbit-rapid-growth-phase-post-iatrogenic-incisional-trauma
#10
Caroline McBurney, Susan Zhang, Sharon Morris
Nodular fasciitis (NF) is a benign, reactive, myofibroblastic proliferative solitary lesion that commonly develops in the subcutaneous or superficial fascia. We present a case of a 35-year-old male with a rapidly enlarging upper eyelid mass postiatrogenic incisional trauma. Subsequent en toto excisional biopsy demonstrated NF. Given the rapid clinical course of this patient and the reactive nature of NF, we hypothesize that the initial incisional trauma likely incited an inflammatory response resulting in rapid proliferation and growth of the lesion...
February 2024: Journal of Surgical Case Reports
https://read.qxmd.com/read/38304953/palmer-nodular-fasciitis-harboring-a-novel-srebf1-usp6-fusion-gene
#11
JOURNAL ARTICLE
Haider A Mejbel, Gene P Siegal, Shi Wei
The diagnosis of low-grade fibroblastic/myofibroblastic tumors of acral sites can be challenging. These tumors encompass a diverse group of neoplasms with a spectrum of biologic potential ranges from benign to overtly malignant. They often demonstrate significant clinical, radiologic, and immunophenotypic overlap, in which the molecular phenotype may play an important diagnostic role to arrive at the final diagnosis. Herein, we report a case of soft tissue mass lesion presented on the palm of an adult patient for four months...
February 2, 2024: International Journal of Surgical Pathology
https://read.qxmd.com/read/38282536/rare-cardiac-tumour-nodular-fasciitis
#12
JOURNAL ARTICLE
Natraj Ballal, Neehar Haryadi, Karl Reyes
Left ventricular tumour is a rare condition in children. The causes include vegetations, thrombus, and fibroma. 2-year-old asymptomatic female presented with an innocent heart murmur at 6 months of age. Subsequent follow-ups at 18 months of age showed left ventricular mass. Surgical pathology revealed "nodular fasciitis." This type of tumour has never been described in the heart before.
January 29, 2024: Cardiology in the Young
https://read.qxmd.com/read/38148839/case-report-angiomatoid-fibrous-histiocytoma-in-the-hand-a-rare-clinical-presentation-and-diagnostic-challenge
#13
Jiro Ichikawa, Tomonori Kawasaki, Hiroki Imada, Masanori Wako, Taro Fujimaki, Rikito Tatsuno, Takahiro Jubashi, Hirotaka Haro
Angiomatoid fibrous histiocytoma (AFH) is a rare tumor of mesenchymal origin occurring in young adults. Based on its clinical course, it is said to have an intermediate potential. We present a case of a 59-year-old woman with AFH in the hand that was difficult to diagnose. A benign soft tissue tumor was suspected on magnetic resonance imaging, and its size and open biopsy suggested nodular fasciitis or inflammatory myofibroblastic tumor. A diagnosis of AFH was eventually made based on the analysis of the resected specimens...
2023: Frontiers in Oncology
https://read.qxmd.com/read/38107840/fibro-osseus-pseudotumor-of-the-digit-a-case-report-and-review-of-literature
#14
Chander Grover, Pratibha Gupta, Chhavi Gupta, Kaniyappan Nambiyar, Shitij Goel
INTRODUCTION: Bony subungual growths arising on the digital tip are uncommon. Among these, subungual exostosis is a common cause. CASE PRESENTATION: We describe a 35-year-old-male patient with a rare occurrence of a fibro-osseus pseudotumor of the digit. It presents with reactive intramembranous ossification, with no continuity with the distal phalanx, helping differentiate it from a subungual exostosis. The patient presented with an asymptomatic subungual growth, lifting up the nail plate distally causing onycholysis...
December 2023: Skin Appendage Disorders
https://read.qxmd.com/read/38107692/imaging-findings-of-nodular-fasciitis-in-breast-including-artificial-intelligence-mammography-and-shear-wave-elastography-a-case-report
#15
So Hyeong Park, Ji Yeon Park, Mee Joo, Jae Il Kim
Nodular fasciitis is a benign fibroblastic proliferation rarely reported in the breast. We report the case of a 55-year-old woman who presented with imaging findings that resembled a malignancy. Mammography revealed an isodense nodule with partially indistinct margin in the right breast, showing the abnormality score 75% on artificial intelligence. Ultrasonography revealed an oval hypoechoic nodule with microlobulated margin, echogenic halo, increased blood flow, and soft elasticity. After core needle biopsy and excision, nodular fasciitis was diagnosed...
November 2023: J Korean Soc Radiol
https://read.qxmd.com/read/38061708/low-grade-myofibroblastic-sarcoma-on-back-with-repeated-localized-recurrence-and-regional-metastasis
#16
Hyeon Jeong Park, Yeon-Gu Choi, Seung-Wan Chae, Won-Serk Kim
Low-grade myofibroblastic sarcoma (LGMS) is a rare spindle cell tumor with indolent course. Due to rarity and low-grade histologic features of LGMS, accurate diagnosis is challenging. We report a 63-year-old female patient with a three-month history of a 3.1 cm×2.5 cm sized, firm, skin-colored, painless, protruding left back mass. Initial excisional biopsy was performed and the mass was diagnosed as nodular fasciitis. After 18 months after excision, the mass recurred with pain and grew larger. Considering the clinical manifestations, diagnostic impression was changed as dermatofibrosarcoma protuberans not nodular fasciitis...
November 2023: Annals of Dermatology
https://read.qxmd.com/read/38025358/case-report-rare-presentation-of-nodular-fasciitis-over-dorsum-of-wrist
#17
Ashootosh Batra, Jaya Batra, Tripti Pathare
INTRODUCTION: Nodular fasciitis is a benign, reactive fibroblastic tumor that usually presents as a rapidly growing lesion with occasional involvement of the deep fascia and muscle. We present a case of nodular fasciitis over the dorsum of the wrist. In our knowledge, this is the first reported case of nodular fasciitis at this location in the literature. CASE REPORT: A 33-year-old South Asian male with a desk job, presented with a rapidly growing lesion over the dorsum of the left wrist over 5 months, associated with pain and restriction of dorsiflexion of wrist...
November 2023: Journal of Orthopaedic Case Reports
https://read.qxmd.com/read/38022190/late-onset-type-1-diabetes-mellitus-and-unexplained-subcutaneous-lesions
#18
Malik A Tunc, Karim Amireh, Kevin Brar, Ramyaprabha Bondalapati, Pedro Novo, Alexey Podcheko Md
Nodular fasciitis is considered a reactive lesion of connective tissue originating from the proliferation of fibroblasts and myofibroblasts. Nodular fasciitis preponderantly localizes within the higher extremities, trunk, head, and neck. We are presenting a report on the case of a 38-year-old Navy pilot who developed nodular lesions in the area of the sternum and upper back and was diagnosed concomitantly with insulin-dependent diabetes mellitus (type 1 diabetes). The patient was treated for diabetic ketoacidosis using intensive insulin therapy protocol, and the nodules were surgically excised...
October 2023: Curēus
https://read.qxmd.com/read/37877075/nodular-fasciitis-of-the-external-auditory-canal-clinical-case-report-and-review-of-the-literature
#19
REVIEW
Adrien Philippart, Jean-Christophe Degols, Jacques Vilain
Nodular fasciitis is a benign reactive soft tissue tumor arising from fibroblasts and myofibroblasts. Its incidence is low and misdiagnosis is frequent especially for malignant lesions. This can lead to inappropriate and unnecessary invasive treatment. Nodular fasciitis of the external auditory canal is extremely rare. So far, around fifteen cases have been reported. We present here the case of a 90-year-old patient with nodular fasciitis of the right external auditory canal. The lesion extends anteriorly for 6...
October 2023: Journal of Otology
https://read.qxmd.com/read/37869315/efficacy-and-safety-of-different-thermal-ablative-therapies-for-desmoid-type-fibromatosis-a-systematic-review-and-meta-analysis
#20
JOURNAL ARTICLE
Kaifeng Huang, Ruixia Hong, Li Luo, Huai Zhao, Yundong Wang, Ying Li, Yaohuang Jiang, Hang Zhou, Fang Li
BACKGROUND: Desmoid-type fibromatosis (DF) is a locally aggressive tumor characterized by peripheral infiltration of neoplastic cells and remote metastasis disability. This systematic review examined the efficacy and safety of thermal ablative therapy for DF tumors. METHODS: A literature search was conducted using PubMed, Web of Science, Cochrane Library, and Embase from January 1, 2000, to November 12, 2022. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement was used to guide literature selection...
October 1, 2023: Quantitative Imaging in Medicine and Surgery
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