Qien He, Guanghui Ying, Xiapei Fei, Chenqin Zha, Zhaogui Chen, Yishu Bao, Jiaorong Long, Zhujun Wang, Xuelin He, Min Xia
INTRODUCTION: Proton pump inhibitors (PPIs) are widely prescribed and generally well tolerated but can rarely cause severe allergic reactions, such as drug rash with eosinophilia and systemic symptoms (DRESS). We report a case of DRESS and renal injury induced by PPIs, and describe the therapeutic process. PATIENT CONCERNS: The patient was a 66-year-old female who complained of fever, pruritus, desquamation, erythema multiforme, and anuria caused by omeprazole taken for 2 weeks to treat abdominal distention...
October 16, 2020: Medicine (Baltimore)
Stephanie L Mawhirt, David Frankel, Althea Marie Diaz
PURPOSE OF REVIEW: COVID-19 (coronavirus viral disease 2019), due to the novel SARS-CoV-2, may present with different types of cutaneous manifestations of varying pathophysiology. During the ongoing pandemic, publications reporting dermatologic findings in COVID-19 continue to emerge. RECENT FINDINGS: Cutaneous vasculopathy and microthrombus-related changes including acral and sacral lesions, retiform purpura, livedo reticularis, and cutaneous vasculitis are notable findings in adult patients...
October 12, 2020: Current Allergy and Asthma Reports
Ana B Arevalo, Rawann Nassar, Satyam Krishan, Priyanka Lakshmanan, Maria Salgado, Priya Chokshi
Background: Rowell's syndrome is comprised of the presentation of erythema multiforme- (EM-) like lesions in association with lupus erythematosus (LE), along with serologies of speckled antinuclear antibodies (ANAs), positive rheumatoid factor (RF), positive anti-La/anti-Ro, and the clinical finding of chilblains. As per the redefined criteria by Zeitouni et al., three major criteria in addition to at least 1 minor criterion are necessary for diagnosis. Case Presentation . A 20-year-old male presented with a one-week history of worsening nonpruritic erythematous maculopapular skin rash (resembling EM) which appeared on the face and subsequently spread to the trunk, arms, legs, palms, and soles...
2020: Case Reports in Rheumatology
Michela De Lucia, Maria Cabré, Daria Denti, Giorgia Mezzalira, Marco Rondena, Tommaso Furlanello
Erythema multiforme (EM), an uncommon immune-mediated skin disorder of cats, conceivably could be triggered by feline herpesvirus type-1 (FHV-1) infection, in a manner analogous to human herpesvirus-associated EM (HAEM). This report describes a 10-year-old Persian-mixed cat with a presumptive diagnosis of HAEM.
September 29, 2020: Veterinary Dermatology
Deepa Chaudhary, Shubham Atal, Ratinder Jhaj, Richa Rupla
Erythema multiforme (EM) is an immunomediated mucocutaneous disorder of usually unknown etiology which has been known to occur following an infection like herpes virus or exposure to drugs. It primarily affects adolescents, young adults, but can occur at any age. Vaccines are also documented as precipitating factors for EM. In the year 2017, the case of a 25-year-old male patient with lesions of EM which appeared after 30 min of administration of tetanus toxoid vaccine is reported here.
July 2020: Indian Journal of Public Health
Atanu Chandra, Swarup Kanta Saha, Aritra Kumar Ray, Parthasarathi Karmakar
Rowell's syndrome is a rare disorder characterised by an association of lupus erythematosus with erythema multiforme (EM)-like skin lesions. EM as the initial clinical presentation of systemic lupus erythematosus is also atypical and even rarer. We report the case of an 18-year-old girl admitted to our hospital with fever and polyarthralgia along with multiple discrete ill-defined target lesions with crust formation over forehead, cheek, external ears, scalp, upper chest and back (predominantly over sun-exposed areas) with ulceration over hard palate...
September 23, 2020: BMJ Case Reports
Daniel Rizo-Potau, Ignasi Marti-Marti, Xavier Fustà-Novell
No abstract text is available yet for this article.
September 17, 2020: Medicina Clínica
Philippe M Burlina, Neil J Joshi, Phil A Mathew, William Paul, Alison W Rebman, John N Aucott
This study examines the use of AI methods and deep learning (DL) for prescreening skin lesions and detecting the characteristic erythema migrans rash of acute Lyme disease. Accurate identification of erythema migrans allows for early diagnosis and treatment, which avoids the potential for later neurologic, rheumatologic, and cardiac complications of Lyme disease. We develop and test several deep learning models for detecting erythema migrans versus several other clinically relevant skin conditions, including cellulitis, tinea corporis, herpes zoster, erythema multiforme, lesions due to tick bites and insect bites, as well as non-pathogenic normal skin...
September 7, 2020: Computers in Biology and Medicine
Giulia Daneshgaran, Danielle P Dubin, Daniel J Gould
BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has affected 18 million people and killed over 690,000 patients. Although this virus primarily causes respiratory symptoms, an increasing number of cutaneous manifestations associated with this disease have been reported. OBJECTIVE: The aim of this review was to collate and categorize the dermatologic findings reported in patients with COVID-19 and identify specific lesions that may facilitate diagnosis and prognostication...
August 31, 2020: American Journal of Clinical Dermatology
Ceren Can, Mehtap Yazicioglu, Selman Gokalp, Nese Ozkayin
Parvovirus B19 has a wide spectrum of clinical manifestations. Erythema multiforme and vasculitis are rarely reported with parvovirus B19 infections. Reactions to insect stings can range from local swelling to life-threatening systemic reactions. There have been rare reports of unusual reactions, such as vasculitis, occurring in a temporal relationship with insect stings. We report an 8-year-old patient having Parvovirus B-19-related erythema multiforme and vasculitis after a yellow jacket bee sting.
July 10, 2020: Journal of Tropical Pediatrics
Juan Monte Serrano, Joana Cruañes Monferrer, Mar García-García, Miguel Fernando García-Gil
No abstract text is available yet for this article.
August 5, 2020: Medicina clínica
Alba Sánchez-Velázquez, Daniel Falkenhain, Raquel Rivera Díaz
No abstract text is available yet for this article.
August 14, 2020: Medicina clínica
Alba Català, Cristina Galván-Casas, Gregorio Carretero-Hernández, Pedro Rodríguez-Jiménez, Daniel Fernández-Nieto, Ana Rodríguez-Villa, Íñigo Navarro-Fernández, Ricardo Ruiz-Villaverde, Daniel Falkenhain-López, Mar Llamas-Velasco, Lucía Carnero-Gonzalez, Juan García-Gavin, Ofelia Baniandrés, Carlos González-Cruz, Víctor Morillas-Lahuerta, Xavier Cubiró, Ignasi Figueras, Gerald Selda-Enriquez, Xavier Fustà-Novell, Mónica Roncero-Riesco, Patrícia Burgos-Blasco, Jorge Romaní, Joaquim Solà-Ortigosa, Ignacio García-Doval
BACKGROUND: A previous study has defined the maculopapular subtype of manifestations of COVID-19. OBJECTIVES: To describe and classify maculopapular eruptions associated with COVI-19. METHODS: We carried out a subanalysis of the maculopapular cases found in the previous cross-sectional study. Using a consensus, we defined 7 clinical patterns. We described patient demographics, the therapy received by the patient and the characteristics of each pattern...
August 10, 2020: Dermatologic Therapy
Danielle Kochen, Raman J Sohal, Amitpal Nat
Acquired perforating collagenosis is a rare disease of altered collagen formation that is extruded through the epidermis. It is most commonly seen in patients with microvascular disease including longstanding diabetes and chronic kidney disease (CKD). Due to the rarity of the disease, no large randomized clinical studies have been performed to determine the most efficacious method of treatment. Therefore, most of the knowledge available for treatment is secondary to the information collected through case reports, case series, and retrospective analyses...
July 14, 2020: Curēus
Andreas Afthinos, Aggeliki Pandi, Maria Horti, Ilias C Papanikolaou
No abstract text is available yet for this article.
2020: Advances in Respiratory Medicine
Raffaele Gianotti, Sebastiano Recalcati, Fabrizio Fantini, Cristina Riva, Mario Milani, Emanuele Dainese, Francesca Boggio
Skin manifestations of COVID-19 infections are diverse and are new to the dermatology community. We had the opportunity to examine the clinical and histopathological features of several patients who were divided into 3 groups. The first group included 8 COVID-19-positive patients who were hospitalized and quarantined at home. The second group included children and young adults who presented with chilblain erythema, erythema multiforme, and urticaria-like lesions. This group of patients was negative for the COVID-19 gene sequences by polymerase chain reaction but had a high risk of COVID-19 infection...
August 2020: American Journal of Dermatopathology
Ana-Maria Muresan, Dieter Metze, Almut Böer-Auer, Stephan A Braun
INTRODUCTION: Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is a clinically very well-defined drug eruption, but the histopathological findings are still considered to be nonspecific. OBJECTIVES: To characterize the histopathological and immunophenotypical features of SDRIFE. MATERIAL AND METHODS: We performed a retrospective study that identified 11 biopsies from 9 patients with SDRIFE. The histopathological features were analyzed in conjunction with the immunohistochemical findings...
June 30, 2020: American Journal of Dermatopathology
Abdulrahman Y Almansouri, Zeyad A Alzahrani
We report a case of 30-year-old female who presented initially with hair loss, photosensitive malar rash, morning stiffness and synovitis. She was diagnosed with Rhupus syndrome based on clinical and laboratory findings. Few months after starting hydroxychloroquine, esomeprazole and azathioprine, and failing methotrexate (because of erosive pill-induced esophagitis), she presented with generalized maculopapular dusky reddish rash in her body, back and extremities. Her anti-double stranded-DNA, anti-nuclear antibody, anti-Ro/SSA and anti-La/SSB were positive...
2020: Open Access Rheumatology: Research and Reviews
Thomas Bapst, Fabrizio Romano, Marie Müller, Marie Rohr
No abstract text is available yet for this article.
June 29, 2020: BMJ Case Reports
Angela Sinadinos, Jonathan Shelswell
Design Case series.Introduction The most common signs and symptoms of SARS-CoV-2 infection include headache, sore throat, hyposmia, hypogeusia, diarrhoea, dyspnoea and pneumonia. Dermatological manifestations have also been reported but few authors have documented oral signs and symptoms. Methods Three cases are reported where oral ulceration or blistering is found in patients with confirmed or suspected COVID-19.Results One patient had serologically confirmed COVID-19, whilst the remaining two cases were only suspected...
June 2020: Evidence-based Dentistry
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