Yasuo Kosugi, Keisuke Sasai, Naoya Murakami, Tatsuki Karino, Yoichi Muramoto, Terufumi Kawamoto, Masaki Oshima, Noriyuki Okonogi, Jun Takatsu, Kotaro Iijima, Shuhei Karube, Akira Isobe, Naoya Hara, Mitsuhisa Fujimaki, Shinichi Ohba, Fumihiko Matsumoto, Koji Murakami, Naoto Shikama
PURPOSE: To determine the efficacy and safety of target volume determination by 18 F-fluorodeoxyglucose positron emission tomography-computed tomography (PET-CT) for intensity-modulated radiation therapy (IMRT) for locally advanced head and neck squamous cell carcinoma (HNSCC) extending into the oral cavity or oropharynx. METHODS: We prospectively treated 10 consecutive consenting patients with HNSCC using IMRT, with target volumes determined by PET-CT. Gross tumor volume (GTV) and clinical target volume (CTV) at the oral level were determined by two radiation oncologists for CT, magnetic resonance imaging (MRI), and PET-CT...
March 15, 2024: EJNMMI Rep