Iliyan Dimitrov, Teodora Stankova, Penka Angelova, Nikolay Boyadjiev, Katerina Georgieva, Ivica Dimov, Anelia Bivolarska, Milena Draganova, Fanka Gerginska, Elena Daskalova, Vilian Gramatikov, Slavi Delchev
The prolonged consumption of a high-fat diet (HFD) leads to abnormal growth of the visceral adipose tissue (VAT), increased macrophage infiltration, and altered secretion of biologically active molecules. This is considered as a precondition for the development of obesity, inflammation, and obesity-related disorders. Therefore, we studied HFD-induced changes in the tissue levels of the inflammatory markers C-reactive protein, serum amyloid-A, and interleukin-4 in healthy male Wistar rats. The animals were first divided at random into two groups subjected to either a standard or a high-fat diet...
April 16, 2024: Nutrients