G Favre, M Beksaç, A Bacigalupo, T Ruutu, A Nagler, E Gluckman, N Russell, J Apperley, J Szer, K Bradstock, A Buzyn, J Matcham, A Gratwohl, N Schmitz
We report graft product stem cell yields and donor safety results of a randomized multicenter study comparing allogeneic peripheral blood stem cell (PBSC) PBSC transplantation with BM transplantation. Matched HLA-identical sibling donors (n=329) were randomized to filgrastim-mobilized PBSC or bone marrow (BM) donation groups. Median yields per kg recipient weight of CD34(+) cells, T cells, and natural killer (NK) cells, respectively, were approximately two-fold, eight-fold, and greater than eight-fold in the PBSC group than in the BM group (CD34(+) cells, 5...
November 2003: Bone Marrow Transplantation