Morgane Van Wettere, Luisa Paulatto, Lucas Raynaud, Onorina Bruno, Audrey Payancé, Aurélie Plessier, Pierre-Emmanuel Rautou, Valérie Paradis, Dominique Cazals-Hatem, Dominique Valla, Valérie Vilgrain, Maxime Ronot
Background & Aims: Hepatobiliary phase (HBP) images can discriminate between benign and malignant liver lesions, but it is unclear if this approach can be used in patients with Budd-Chiari syndrome (BCS). Thus, we aimed to assess the diagnostic utility of HBP images in patients with BCS. Methods: This retrospective study included all patients admitted to our institution with a diagnosis of BCS and focal liver lesions on hepatobiliary contrast agent-enhanced MR imaging (HBCA-MRI) from 2000 to 2019...
June 2020: JHEP reports: innovation in hepatology
Yan-Wei Zeng, Chao Liu, Mei-Pan Yin, Yue Zhao, Zhi-Wei Wang, Peng-Li Zhou, Yao-Zhen Ma, Chun-Xia Li, Gang Wu
OBJECTIVE: Our study aimed to evaluate the safety and efficacy of sequential interventional therapy for Budd-Chiari syndrome (BCS) caused by obstruction of the inferior vena cava (IVC) with fresh thrombus in the IVC. METHODS: Full medical records were obtained for 20 patients with BCS associated with fresh IVC thrombus who received sequential interventional therapy from 2014 to 2019 at our hospital. All patients underwent small-diameter percutaneous transluminal angioplasty (PTA) balloon catheter predilation combined with sequential catheter-directed thrombolysis and large-diameter PTA balloon dilation...
May 14, 2020: Journal of Vascular Surgery. Venous and Lymphatic Disorders
Leonard Naymagon
Venous thrombosis within the hepatic vasculature is associated with a distinct array of risk factors, characteristics, and potential complication. As such, it entails unique management considerations and strategies relative to the more common categories of venous thromboembolic disease. Although broadly divided into thrombosis of the afferent vasculature (the portal venous system) and efferent vasculature (the hepatic venous system), presentations and management strategies within these groupings are heterogeneous...
May 11, 2020: Translational Research: the Journal of Laboratory and Clinical Medicine
Chalermrat Bunchorntavakul, K Rajender Reddy
Epstein-Barr virus (EBV) and cytomegalovirus (CMV) infections are common and are associated with a variety of liver manifestations. EBV and CMV infections, in immunocompetent hosts, commonly manifest as acute hepatitis, with severity varying from asymptomatic, self-limited icteric hepatitis to acute liver failure. Atypical manifestations, such as cholestasis, chronic hepatitis, precipitation of acute-on-chronic liver failure, and autoimmune hepatitis, are reported with EBV infection, whereas cholestasis, portal vein thrombosis, and Budd-Chiari syndrome are reported with CMV infection...
June 2020: Gastroenterology Clinics of North America
R X Ge, H Y Li, H M Wang, L Li, Y Y Wang, L H Zhong, X Y Wang, Y Lu, X T Wang
Objective: To explore the correlation between prenatal clinical data with etiological diagnosis and neonatal outcome in isolated fetal ascites. Methods: Totally, 36 pregnancy cases diagnosed as isolated fetal ascites by ultrasound in Provincial Hospital Affiliated to Shandong University from June 22nd, 2016 to September 28th, 2018 were collected. Invasive prenatal diagnosis was performed by taking fetal cord blood, amniotic fluid, and fetal ascites respectively for cytogenetics, molecular genetics and biochemical examination and the impact of intrauterine therapeutic procedures on neonatal outcomes was evaluated as well...
April 25, 2020: Zhonghua Fu Chan Ke za Zhi
Sudheer K Vuyyuru, Shivanand Gamanagatti, Shalimar
Budd-Chiari syndrome may rarely occur as a complication of Behcet's disease, and presentation with thrombosis of both inferior vena cava (IVC) and hepatic veins is rarer still. We present a young woman with Behcet's disease who presented with acute Budd-Chiari syndrome, with thrombosis of IVC and all 3 hepatic veins. An IVC stent was placed, followed by a transjugular intrahepatic portosystemic shunt through the IVC stent. On follow-up, despite oral anticoagulants and oral steroids, she developed recurrent thrombosis twice within a 1-year span...
March 2020: ACG Case Reports Journal
Andrea Mancuso, Michele Amata, Flavia Politi, Mario Mitra, Maria Grazia Laura Marsala, Alberto Maringhini
No abstract text is available yet for this article.
April 14, 2020: American Journal of Gastroenterology
Audrey Coilly, Pascal Potier, Pierre Broué, Ilias Kounis, Dominique Valla, Sophie Hillaire, Vincent Lambert, Danielle Dutheil, Virginia Hernández-Gea, Aurélie Plessier, Valérie Vilgrain, Christophe Bureau
No abstract text is available yet for this article.
April 2, 2020: Clinics and Research in Hepatology and Gastroenterology
Slaven Gojkovic, Ivan Krezic, Borna Vrdoljak, Dominik Malekinusic, Ivan Barisic, Andreja Petrovic, Katarina Horvat Pavlov, Marijan Kolovrat, Antonija Duzel, Mario Knezevic, Katarina Kasnik Kovac, Domagoj Drmic, Lovorka Batelja Vuletic, Antonio Kokot, Alenka Boban Blagaic, Sven Seiwerth, Predrag Sikiric
BACKGROUND: Recently, as a possible therapy resolving solution, pentadecapeptide BPC 157 therapy, has been used in alleviating various vascular occlusion disturbances. BPC 157 was previously reviewed as novel mediator of Robert cytoprotection and endothelium protection in the stomach, and gut-brain axis, beneficial therapy in gastrointestinal tract, with particular reference to vascular recruitment, ulcerative colitis and tumor cachexia, and other tissues healing. Here we raised new hypothesis about BPC 157 therapy in the Budd-Chiari syndrome in rats, rapid bypassing of the suprahepatic inferior caval vein occlusion, and rats recovery with the active and effective pharmacotherapy treatment...
March 13, 2020: World Journal of Gastrointestinal Pathophysiology
Peng-Xu Ding, Tao Zhou, Xin-Wei Han, Hai-Tao Ma, Chao Liu, Jia-Yin Ding, Edward Wolfgang Lee
Budd-Chiari syndrome (BCS) is an uncommon disorder defined as an obstruction of the hepatic venous outflow. Percutaneous transluminal balloon angioplasty (PTA) is a less invasive treatment option for BCS patients. However, there are no reports regarding inferior vena cava (IVC) rupture caused by perforation route through a collateral vein during treatment of BCS. Here, we report a male patient with BCS who had a long segmental obstruction of the IVC and its collateral vessels. Here, IVC rupture occurred at the distal end of the obstructed IVC during a percutaneous angioplasty; the rupture was repaired successfully with an endovascular stent graft...
March 20, 2020: Annals of Vascular Surgery
Yu Zhang, Ping Xie, Chong Yang, Hongji Yang, Jun Liu, Guo Zhou, Shaoping Deng, Wan Yee Lau
BACKGROUND AND AIMS: Infiltration of hepatic venous outflow in hepatic alveolar echinococcosis can lead to development of Budd-Chiari syndrome. Medical treatment of this condition is generally unsatisfactory. Radical hepatic resection is impossible for extensive parasitic involvement of liver. This is a case report on a patient who was successfully treated with percutaneous stenting of left hepatic vein followed by Ex vivo Liver Resection and Autotransplantation (ELRA). METHODS: Using the transjugular approach, a metal mesh stent was placed in the left hepatic vein of a 45-year-old man who presented with Budd-Chiari syndrome...
March 9, 2020: International Journal of Surgery Case Reports
Thibault Fraisse, Léa Savey, Véronique Hentgen, Linda Rossi-Semerano, Isabelle Koné-Paut, Gilles Grateau, Sophie Georgin-Lavialle, Stéphanie Ducharme-Bénard
INTRODUCTION: Familial Mediterranean fever (FMF), the most frequent autoinflammatory disease, is caused by mutations in the MEFV gene. It is characterized by recurrent febrile attacks of polyserositis. Liver abnormalities may develop during its course, but they remain poorly defined. OBJECTIVE: To describe liver involvement in FMF patients. METHODS: A systematic search was conducted through PubMed/Medline and Embase from 1946 to January 2020...
June 2020: Liver International: Official Journal of the International Association for the Study of the Liver
Tarık Onur Tiryaki, İpek Yönal Hindilerden, Gülçin Yegen, Meliha Nalçacı
No abstract text is available yet for this article.
March 4, 2020: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
L H Li, G Zhang, X W Dang, L Li
Prevention and control about the situation of 2019 coronavirus disease (COVID-19) are grim at present. In addition to supporting the frontline actively, medical workers in general surgery spare no efforts in making good diagnosis and treatment of specialized diseases by optimizing treatment process, providing medical advice online, mastering indications of delayed operation and emergency operation reasonably, etc. Budd-Chiari syndrome is a complex disorder, and severity of the disease varies, serious cases can be life threatening...
February 28, 2020: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
Suxin Li, Na Huang, Xiaowei Dang, Liang Li, Zhenzhen Li, Chen Zhang, An Jiang, Guangyao Kong, Fanpu Ji, Jun Yang, Zongfang Li
The difference of splenic pathologic alterations and immune function changes in portal hypertension (PHT) with different etiology is unclear. We aimed to investigate the differences between the hypersplenic patients with hepatitis B virus (HBV)-related PHT and Budd-Chiari syndrome (B-CS). A total of 93 patients with hypersplenism due to Chinese primary B-CS (B-CS group), 105 patients with hypersplenism due to HBV-related cirrhosis (HBV/PHT group), and 31 healthy people (control group) were included in this study retrospectively...
March 2020: Viral Immunology
Crhistian-Mario Oblitas, Neera Toledo-Samaniego, Ainhoa Fernández-Yunquera, Fernando Díaz-Fontenla, Francisco Galeano-Valle, Jorge Del-Toro-Cervera, Rafael Bañares-Cañizares, Pablo Demelo-Rodriguez
Budd-Chiari syndrome (BCS) is characterized by an obstruction of hepatic venous outflow from small hepatic veins to inferior vena cava, caused by acute thrombosis or its fibrous sequellae. An underlying myeloproliferative neoplasm is present in 50% of cases. Clinical manifestations are widely variable, from asymptomatic to fulminant episodes. Long-term complications range from cirrhosis to hepatocellular carcinoma. Behçet's disease (BD) is a rare recurrent inflammatory multisystemic disorder characterized by recurrent skin-mucosa lesions and systemic involvement...
February 17, 2020: Clinical Journal of Gastroenterology
Paris Charilaou, Kalpit Devani, Romela Petrosyan, Chakradhar Reddy, Nikolaos Pyrsopoulos
BACKGROUND: It has been reported that transjugular intrahepatic portosystemic shunting (TIPS) might be utilized as a salvage option for hepatorenal syndrome (HRS), while randomized controlled trials are pending and real-world contemporary data on inpatient mortality is lacking. METHODS: We conducted an observational retrospective cohort study from the National Inpatient Sample from 2005 to 2014. We included all adult patients admitted with HRS and cirrhosis, using ICD 9-CM codes...
February 15, 2020: Digestive Diseases and Sciences
Xin Lu, Xijuan Ma, Kai Xu, Jichen Wang, Chun Yang
PURPOSE: The purpose of this study was to analyze inferior vena cava (IVC) obstruction in Budd-Chiari syndrome (BCS) using rapid quantitative phase-contrast (PC) magnetic resonance (MR) imaging and compare the diagnostic efficacy of PC and MR venography (MRV) to explore the clinical prospects of applying PC quantitative diagnosis in IVC obstruction in BCS. MATERIALS AND METHODS: PC quantitative data and MRV qualitative data obtained in 35 DSA-recognized inferior vena cava obstruction in BCS patients and 35 patients with liver focal lesions found in physical examination were analyzed and compared...
February 13, 2020: Abdominal Radiology
Mayank Jain, Jayanthi Venkataraman, Joy Varghese, Mukul Vij, Mettu S Reddy, Mohamed Rela
Background and Aim: To determine the concordance of liver explants with the pretransplant diagnosis. Methods: This was a retrospective analysis of 251 liver explants. Patient information included demography, comorbidity, and etiological diagnosis. Final diagnosis was based on morphological and histological findings. For non-alcoholic steatohepatitis (NASH) and cryptogenic cirrhosis, we investigated comorbid states such as obesity, hypertension, and diabetes. Chi square test and Cohen's Kappa value were used...
February 2020: JGH open: an open access journal of gastroenterology and hepatology
Steffen Koschmieder
Patients with myeloproliferative neoplasms (MPNs), such as polycythemia vera, essential thrombocythemia, and primary myelofibrosis, are at increased risk for arterial and venous thrombosis/thromboembolism. In particular, the risk of splanchnic venous thrombosis, such as portal vein thrombosis or Budd-Chiari syndrome, is significantly higher in patients with MPN than in the normal population. At the same time, MPN patients are at increased risk for severe bleeding. Therefore, the treatment of patients with MPN must be based on their suspected probability of thrombosis/thromboembolism and bleeding...
February 2020: Hämostaseologie
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