Michael S Bloom, Neil J Perkins, Lindsey A Sjaarda, Sunni L Mumford, Aijun Ye, Keewan Kim, Daniel L Kuhr, Carrie J Nobles, Matthew T Connell, Enrique F Schisterman
BACKGROUND: Obesity, a body mass index (BMI) ≥30 kg/m2 , is linked to infertility, potentially through a greater risk of anovulation due to elevated androgens. Yet, previous studies have not directly assessed the impact of adiposity, or body fat, on anovulation in the absence of clinical infertility. OBJECTIVE: To characterise the associations between adiposity and anovulation among women menstruating on a regular basis. METHODS: Women from the EAGeR trial (n = 1200), a randomised controlled trial of low-dose aspirin and pregnancy loss among women trying to conceive, were used to estimate associations between adiposity and incident anovulation...
October 26, 2020: Paediatric and Perinatal Epidemiology