Chenying Gao, Kaina Zhang, Fanfan Liang, Wenzhuo Ma, Xixi Jiang, Hongying Wang, Heqin Zhan, Enikö Sonkoly, Hao Hu, Zhenghang Zhao
Neointimal hyperplasia is the major cause of carotid stenosis after vascular injury, which restricts the long-term efficacy of endovascular treatment and endarterectomy in preventing stenosis. Ginsenoside Re (Re) is a major active ingredient of ginseng having multifaceted pharmacological effects on the cardiovascular system, and is a potential treatment for restenosis. In this study, we demonstrated that Re treatment significantly inhibited vascular injury-induced neointimal thickening, reduced the intimal area and intima/media (I/M) ratio, increased the lumen area, and inhibited pro-inflammatory cytokines...
June 12, 2021: Food & Function
Yong Liu, Guangqin Li
OBJECTIVE: The aim of the present study was to determine whether there is a correlation between thrombotic pathology and prognosis of endovascular treatment (EVT) for acute ischemic stroke (AIS). METHODS: Thrombi were taken from 58 patients with cerebral ischemic thrombosis who were consecutively selected for EVT for AIS. The collected thrombi then underwent hematoxylin-eosin staining for pathological examinations to determine the red blood cell (RBC) ratio and fibrin/platelet components...
June 8, 2021: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Brooke L Belanger, Michael B Avery, Arindom Sen, Muneer Eesa, Alim P Mitha
BACKGROUND: Creating aneurysm sizes in animal models that resemble human aneurysms is essential to study and test neuroendovascular devices. The commonly used rabbit surgical elastase model, however, produces saccular aneurysms that are smaller than those typically treated in humans. The goal of this study was to determine whether an increased vessel stump length and the addition of calcium chloride to the incubation solution has an effect on the resulting aneurysm size. METHODS: Using a modified aneurysm creation method, thirty two female New Zealand White rabbits underwent aneurysm creation procedures...
June 8, 2021: World Neurosurgery
Yuxi Zhao, Tao Li, Mingwei Wu, Zhaoxiang Zeng, Minxin Gao, Xianhao Bao, Ziyi Xu, Jian Zhou, Jiaxuan Feng, Rui Feng, Zaiping Jing
OBJECTIVES: We sought to explore the efficacy of the endovascular repair of an ascending aortic aneurysm with aortic and mitral regurgitation by 2 novel valved stents. METHODS: We established models of ascending aortic aneurysms combined with aortic and mitral regurgitation in 10 pig hearts, then implanted self-expanding aortic fenestrated and mitral valved stents via the transapical approach. We applied a fluoroscopy-guided in vitro setting to test the approach, then analysed continuous circulating flushing at 37°C...
June 11, 2021: Interactive Cardiovascular and Thoracic Surgery
Henry David
Acute pediatric stroke is growing in incidence with the longer survivorship of children with medical complexities, yet detection and treatment of this disease continues to be met with limitations. It is essential for the frontline provider to appropriately identify various presentations of acute pediatric stroke for timely management to occur. Although studies in thrombolytic and endovascular recanalization therapies are limited, the safety and efficacy of these treatments continues to be explored. As pediatric tertiary care centers improve their stroke management, it is increasingly important to implement hospital protocols with a multifaceted approach...
June 2021: Pediatric Annals
Ke-Cheng Chen, I-Hui Wu, Chih-Yang Chang, Pei-Ming Huang, Mong-Wei Lin, Jang-Ming Lee
No abstract text is available yet for this article.
June 11, 2021: Annals of Surgical Oncology
Aizat Drahman, Diederick Willem De Boo, Barry Springthorpe, Arvind Deshpande
BACKGROUND: Endoleaks after endovascular aortic aneurysm repair (EVAR) occur frequently with type 2 being the most common. Treatment of type 2 endoleaks is indicated if the aneurysmal sac increases in size. CASE REPORT: In this case report, we will discuss a patient who presented with aneurysmal sac size increase 11 years after undergoing EVAR for an asymptomatic abdominal aortic aneurysm which extended into the iliac arteries. Multi-phase CT demonstrated an endoleak with features commonly seen in type 2 endoleaks; pooling of contrast near a lumbar artery orifice on the angiographic phase which increases during the delayed phase...
June 11, 2021: CVIR Endovascular
Spyridon N Mylonas, Konstantinos G Moulakakis, Nikolaos Kadoglou, Constantinos Antonopoulos, Thomas E Kotsis, John Kakisis, Konstantinos Katsenis, Christos Liapis
PURPOSE: The aim of the present study was to investigate a potential difference on the arterial stiffness among aneurysm patients and non-aneurysm controls, as well as to explore potential changes between patients treated either with endovascular or open repair. MATERIALS AND METHODS: A 110 patients with an infrarenal AAA were prospectively enrolled in this study. Fifty-six patients received an EVAR, whereas 54 patients received an open surgical repair. Moreover, 103 gender and age-matched subjects without AAA served as controls...
June 11, 2021: Vascular and Endovascular Surgery
Robert Dunlap, Sean Golden, Gray R Lyons
Portal vein aneurysm (PVA) is a rare entity that can lead to hemorrhage or thrombosis. Although there is no standard treatment, most cases can be managed conservatively; intervention is reserved for symptomatic or enlarging aneurysms. For patients who are not surgical candidates due to cirrhosis and portal hypertension, endovascular creation of a trans-jugular intrahepatic porto-systemic shunt (TIPS) is an option to reduce portal venous pressure. This report describes a case of an enlarging PVA successfully treated with TIPS in a patient with cryptogenic cirrhosis...
June 11, 2021: Vascular and Endovascular Surgery
Alba Méndez Fernández, Jorge Fernández Noya, Nilo J Mosquera Arochena, Jorge Vidal Rey, Pablo Calvin Álvarez, Francisco José Franco Meijide, Rosa Villardefrancos Gil
OBJECTIVE: The objective of this study is to report the medium-term results of GORE® EXCLUDER® Iliac Branch Endoprosthesis (IBE, W. L. Gore & Associates, Flagstaff, Ariz) for the treatment of aortoiliac aneurysms by using the GALIBER registry. METHODS: Patients with aortoiliac or isolated common iliac/hypogastric aneurysms treated with Iliac Branch Endoprosthesis device between January 2014 and May 2019 were prospectively collected from 5 centers. Demographic, clinical, and radiologic data were extracted from electronic databases...
June 11, 2021: Vascular
Carlos Real, David Vivas, Isaac Martínez, Federico Ferrando-Castagnetto, Julio Reina, Ángel Nava-Muñoz, Javier Serrano, Isidre Vilacosta
Background: Coronary subclavian steal syndrome (CSSS) is an uncommon complication observed in patients after coronary artery bypass surgery with left internal mammary artery (LIMA) grafts. It is defined as coronary ischaemia due to reversal flow from the LIMA to the left subclavian artery (SA) when a proximal left SA stenosis is present. In practice, the entire clinical spectrum of ischaemic heart disease, ranging from asymptomatic patients to acute myocardial infarction, may be encountered...
March 2021: European Heart Journal. Case Reports
Shengli Shen, Yingjin Wang, Xudong He, Ning Ma, Feng Gao, Ligang Song, Xuan Sun, Lian Liu, Zhongrong Miao, Hongzhou Duan, Dapeng Mo
Background: Endovascular treatment for intracranial atherosclerotic stenosis (ICAS) has been developed. However, the intracranial internal carotid artery (ICA) presents a particular challenge due to the location and tortuous route, and the outcomes of endovascular treatment in patients with stenosis of the intracranial ICA still have not been reported. This article retrospectively investigated the 30-day and 1-year outcomes of tailored endovascular treatment for patients with severe intracranial ICA stenosis from a single center...
2021: Frontiers in Neurology
Hubert Lee, Ayman M Qureshi, Nils H Mueller-Kronast, Osama O Zaidat, Michael T Froehler, David S Liebeskind, Vitor M Pereira
Background: The indications for mechanical thrombectomy in acute ischemic stroke continue to broaden, leading neurointerventionalists to treat vessel occlusions at increasingly distal locations farther in time from stroke onset. Accessing these smaller vessels raises the concern of iatrogenic subarachnoid hemorrhage (SAH) owing to increasing complexity in device navigation and retrieval. This study aims to determine the prevalence of SAH following mechanical thrombectomy, associated predictors, and resulting functional outcomes using a multicenter registry and compare this with a systematic review and meta-analysis of the literature...
2021: Frontiers in Neurology
Qian Yu, Chenyu Liu, Biagio Collura, Rakesh Navuluri, Mikin Patel, Zhiyong Yu, Osman Ahmed
BACKGROUND: To conduct a meta-analysis to assess the safety and efficacy of prophylactic transcatheter arterial embolization (PTAE) for the treatment of high-risk bleeding peptic ulcers after achieving endoscopic hemostasis. METHODS: PubMed and Cochrane Library were queried for full-text articles published up to December 2019. The following keywords were used: "prophylactic embolization", "supplement embolization", "gastrointestinal bleeding", and "ulcer bleeding"...
June 10, 2021: World Journal of Emergency Surgery: WJES
Peixian Gao, Changliang Li, Xuejun Wu, Gang Li, Dianning Dong, Jiaxin Qi
PURPOSE: To evaluate the safety and efficacy of transbrachial and transfemoral approaches combined with visceral protection for the endovascular treatment of juxtarenal aortoiliac occlusive disease (AIOD) over an average 19-month follow-up period. METHODS: In this retrospective analysis, all patients with juxtarenal AIOD at a single institution were reviewed from June 2015 to January 2020. Patient characteristics, angiographic results, and follow-up outcomes were retrospectively recorded...
June 10, 2021: Vascular
Muhammed Süleymanoğlu, Cengiz Burak, Ayça Gümüşdağ, Murat Çap, Ayhan Şenol, Şerif Hamideyin, Ezgi Güzel, İbrahim Rencüzoğulları, Yavuz Karabağ, Metin Çağdaş
BACKGROUND: Peripheral artery disease (PAD) is part of the systemic atherosclerotic process that is highly associated with cardiovascular diseases. Despite successful endovascular treatment (EVT) strategies, mortality and morbidity rates still remain higher in PAD patients. C-reactive protein (CRP) and albumin are biomarkers of inflammation and malnutrition that play key roles in the progression of peripheral arterial disease. In this study, we aimed to investigate the relationship between CRP-to-albumin ratio (CAR) and mortality and amputation-free survival in patients with PAD after successful EVT...
June 10, 2021: Vascular
Michele Umbrello, Nicola Brena, Ruggero Vercelli, Riccardo Alessandro Foa, Marco Femia, Umberto Rossi, Gian Marco Podda, Francesca Cortellaro, Stefano Muttini
Several cases of deep venous thrombosis in people who had recently received Vaxzevria (previously known as COVID-19 Vaccine AstraZeneca) have recently been reported, mainly presenting as cerebral vein/cerebral venous sinus thrombosis. This syndrome has been termed "vaccine-induced immune thrombotic thrombocytopenia (VITT)". Acute spleno-porto-mesenteric vein thrombosis is an uncommon but serious condition with potential sequelae, such as small-bowel gangrene and end-stage liver failure. We describe a case of concomitant thrombosis of portal, superior mesenteric and splenic veins in a young female patient with no other risk factors who received Vaxzevria (previously ChAdOx1 nCoV-19 vaccine, AstraZeneca) 17 days before...
June 4, 2021: Journal of Critical Care
Rajesh Vijayvergiya, Ganesh Kasinadhuni, Pruthvi C Revaiah, Anupam Lal, Ashish Sharma, Rupesh Kumar
Background: Aortobronchial fistula (ABF) formation following the rupture of thoracic pseudoaneurysm is a rare clinical entity. Its aetiology includes atherosclerosis, infections, trauma, post-surgery, and post-endovascular aortic repair. The clinical presentation of ABF includes intermittent or massive haemoptysis, acute respiratory distress, hypotension, and even death. These patients require an emergency aortic intervention to stop active haemorrhage. Thoracic endovascular aortic repair (TEVAR) is a less invasive, safe, and effective treatment compared to conventional open surgical repair...
December 2020: European Heart Journal. Case Reports
Maria Joh, Kush R Desai
Nonthrombotic iliac vein lesions (NIVLs) most frequently result from extrinsic compression of various segments of the common or external iliac vein. Patients develop symptoms associated with chronic venous insufficiency (CVI); female patients may develop symptoms of pelvic venous disease. Given that iliac vein compression can be clinically silent, a thorough history and physical examination is mandatory to exclude other causes of a patient's symptoms. Venous duplex ultrasound, insufficiency examinations, and axial imaging are most commonly used to assess for the presence of a NIVL...
June 2021: Seminars in Interventional Radiology
Joseph Alden Herrold, Sakib Adnan, Anna Romagnoli, Marta J Madurska, Richard Betzold, Joseph DuBose, Thomas Scalea, Jonathan J Morrison
Endovascular hemostasis is commonplace with many practitioners providing services. Accruing sufficient experience during training could allow acute care surgeons (ACS) to expand their practice. We quantified case load and training opportunities at our center, where dedicated dual-trained ACS/vascular surgery faculty perform these cases. Our aim was to assess whether ACS fellows could obtain sufficient experience in 6 months of their fellowship in order to certify in these techniques, per the requirements of other specialties...
April 8, 2021: Journal of Trauma and Acute Care Surgery
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