keyword
https://read.qxmd.com/read/35848818/rapid-in-situ-detection-of-thc-and-cbd-in-cannabis-sativa-l-by-1064-nm-raman-spectroscopy
#21
JOURNAL ARTICLE
Stefania Porcu, Enrica Tuveri, Marco Palanca, Claudia Melis, Ignazio Macellaro La Franca, Jessica Satta, Daniele Chiriu, Carlo Maria Carbonaro, Pierluigi Cortis, Antonio De Agostini, Pier Carlo Ricci
The need to find a rapid and worthwhile technique for the in situ detection of the content of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in Cannabis sativa L. is an ever-increasing problem in the forensic field. Among all the techniques for the detection of cannabinoids, Raman spectroscopy can be identified as the most cost-effective, fast, noninvasive, and nondestructive. In this study, 42 different samples were analyzed using Raman spectroscopy with 1064 nm excitation wavelength. The use of an IR wavelength laser showed the possibility to clearly identify THC and CBD in fresh samples, without any further processing, knocking out the contribution of the fluorescence generated by visible and near-IR sources...
July 26, 2022: Analytical Chemistry
https://read.qxmd.com/read/35841215/key-parameters-of-non-ablative-fractional-laser-pretreatments-for-enhanced-topical-uptake
#22
JOURNAL ARTICLE
Jordan V Wang, Paul M Friedman, Jenny Johnson, Adarsh Konda, Linda Keator, Roy G Geronemus
BACKGROUND: The uptake of topical formulations can be enhanced through laser pretreatments. Newer technologies, such as non-ablative fractional lasers (NAFLs), can target dermal tissues and spare the stratum corneum (SC), which can mitigate common side effects associated with ablative laser treatment. OBJECTIVE: To discuss the parameters of 2 NAFL pretreatment systems (1440-nm/1927-nm diode system or 1550-nm erbium-doped glass/1927-nm thulium system), which can be paired with topicals to improve their cutaneous uptake...
September 2022: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/35786187/a-co-encapsulation-of-coenzyme-q10-and-curcumin-in-liposomes-coated-with-chitosan-q10-cur-lip-chi-with-enhanced-solubility-and-stability-for-good-release-performance-and-antioxidative-activity
#23
JOURNAL ARTICLE
Linjin Yu, Chuyan Chao, Qinglan Li, Songling Ye, Jiasen Lin, Shuling Zhong, Qiancheng Xuan, Kailin Xu, Suqing Zhao
BACKGROUND: Coenzyme Q10 (Q10) is a powerful lipophilic antioxidant with poor solubility in aqueous media. Curcumin (Cur) is a natural polyphenolic phytochemical molecule with poor aqueous solubility. Liposome is an improved administration of drugs yet with some drawbacks, such as low bioavailability, poor water solubility. It's found biocompatible and permeable for nutraceutical delivery. Chitosan, a hydrophilic polymer, is often used as a polymer coating for its good biocompatible and biodegradable properties, and its relatively low toxicity level...
June 30, 2022: Current Drug Delivery
https://read.qxmd.com/read/35598290/hemin-mitigates-contrast-induced-nephropathy-by-inhibiting-ferroptosis-via-ho-1-nrf2-gpx4-pathway
#24
JOURNAL ARTICLE
Zhao Gao, Ziyue Zhang, Daqian Gu, Yunqian Li, Kun Zhang, Xiaoli Dong, Lingli Liu, Jiye Zhang, Jimin Chen, Duozhi Wu, Min Zeng
Contrast-induced nephropathy (CIN) is a common complication with adverse outcome after iodinated-contrast injection, yet still lacking effective medication. Heme oxygenase-1 (HO-1) has been reported to play an important role against renal injuries. Hemin, a HO-1 inducer and anti-porphyria medicine, may have a promising effect against CIN. In this study, we aim to investigate the effect of hemin on CIN model and the underlying molecular mechanisms in human proximal tubule epithelial cells (HK-2). To mimic a common condition in percutaneous coronary intervention (PCI) patients, CIN was induced by intravenous iopromide in high-fat fed diabetic rats...
August 2022: Clinical and Experimental Pharmacology & Physiology
https://read.qxmd.com/read/35527340/spontaneous-formation-of-lead-free-cs-3-cu-2-i-5-quantum-dots-in-metal-organic-frameworks-with-deep-blue-emission
#25
JOURNAL ARTICLE
Yuqing Zhang, Yong He, Zhenyu Tang, Wenjin Yu, Zehao Zhang, Zhijian Chen, Lixin Xiao, Jun-Jie Shi, Shufeng Wang, Bo Qu
All-inorganic lead-free Cs3 Cu2 I5  perovskite-derivant quantum dots (QDs) have attracted tremendous attention due to their nontoxicity and unique optoelectronic properties. However, the traditional hot-injection method requires high temperatures and multiple ligands to confine the growth of QDs. Herein, a strategy is reported to spontaneously synthesize ultrasmall Cs3 Cu2 I5  QDs within metal-organic-frameworks (MOFs) MOF-74 at room temperature (RT) with an average diameter of 4.33 nm. The obtained Cs3 Cu2 I5  QDs exhibit an evident deep-blue emission with Commission Internationale de L'Eclairage coordinates of (0...
June 2022: Small
https://read.qxmd.com/read/35503388/raman-spectroscopy-and-sciatic-functional-index-sfi-after-low-level-laser-therapy-lllt-in-a-rat-sciatic-nerve-crush-injury-model
#26
JOURNAL ARTICLE
Melissa de Almeida Melo Maciel Mangueira, Egas Caparelli-Dáquer, Ozimo Pereira Gama Filho, Diogo Souza Ferreira Rubim de Assis, Janyeid Karla Castro Sousa, Willy Leite Lima, Antonio Luiz Barbosa Pinheiro, Landulfo Silveira, Nilton Maciel Mangueira
Axonotmesis causes sensorimotor and neurofunctional deficits, and its regeneration can occur slowly or not occur if not treated appropriately. Low-level laser therapy (LLLT) promotes nerve regeneration with the proliferation of myelinating Schwann cells to recover the myelin sheath and the production of glycoproteins for endoneurium reconstruction. This study aimed to evaluate the effects of LLLT on sciatic nerve regeneration after compression injury by means of the sciatic functional index (SFI) and Raman spectroscopy (RS)...
September 2022: Lasers in Medical Science
https://read.qxmd.com/read/35427312/thulium-doped-fluorotellurite-glass-fibers-for-broadband-s-band-amplifiers
#27
JOURNAL ARTICLE
Junjie Wang, Zhixu Jia, Chuanze Zhang, Yan Sun, Yasutake Ohishi, Weiping Qin, Guanshi Qin
We demonstrated broadband S-band (1460-1530 nm) amplification in Tm3+ -doped fluorotellurite glass fibers (TDFTFs) by using a 1400/1570 nm dual-wavelength pump technique. TDFTFs based on TeO2 -BaF2 -Y2 O3 (TBY) glass were fabricated by using a rod-in-tube method. For an input signal power of 0 dBm (or 1 mW), a broadband positive net gain ranging from <1440 nm to 1546 nm was achieved in a 1.55-m-long TDFTF with a Tm3+ doping concentration of ∼4000 ppm, as the pump powers of the 1400 nm and 1570 nm lasers were 1...
April 15, 2022: Optics Letters
https://read.qxmd.com/read/35104044/cellulite-presentation-and-management
#28
REVIEW
Gulhima Arora, Anant Patil, Zahra Hooshanginezhad, Klaus Fritz, Carmen Salavastru, Martin Kassir, Mitchel P Goldman, Michael H Gold, Maurice Adatto, Stephan Grabbe, Mohamad Goldust
BACKGROUND: Cellulite is a common dermatological condition with a female preponderance, affecting up to 90% post-pubertal females. It is characterized with dimpling and denting of the skin surface, giving it a Peau d'orange appearance. Once considered to be a benign physiological isolated skin condition of only an esthetic concern, cellulite is now considered a pathological entity with systemic associations and a negative psychological impact on patients. AIMS: The objective of this article was to discuss etiology, pathophysiology, and treatment of cellulite...
April 2022: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/34731846/droplet-epitaxy-of-inas-inp-quantum-dots-via-movpe-by-using-an-ingaas-interlayer
#29
JOURNAL ARTICLE
Elisa M Sala, Max Godsland, Young In Na, Aristotelis Trapalis, Jon Heffernan
InAs quantum dots (QDs) are grown on an In0.53 Ga0.47 As interlayer and embedded in an InP(100) matrix. They are fabricated via droplet epitaxy (DE) in a metal organic vapor phase epitaxy (MOVPE) reactor. Formation of metallic indium droplets on the In0.53 Ga0.47 As lattice-matched layer and their crystallization into QDs is demonstrated for the first time in MOVPE. The presence of the In0.53 Ga0.47 As layer prevents the formation of an unintentional non-stoichiometric 2D layer underneath and around the QDs, via suppression of the As-P exchange...
November 19, 2021: Nanotechnology
https://read.qxmd.com/read/34463011/tailored-chiral-copper-selenide-nanochannels-for-ultrasensitive-enantioselective-recognition-and-detection
#30
JOURNAL ARTICLE
Dan Meng, Changlong Hao, Jiarong Cai, Wei Ma, Chen Chen, Chuanlai Xu, Liguang Xu, Hua Kuang
We constructed a tailorable membrane channel system consisting of penicillamine molecules intercalated in copper selenide nanoparticles (Cu2-x Se NPs), which exhibited circular dichroism (CD) bands in the near infrared region (CD, 800-1600 nm) with a maximum intensity of 164.5 mdeg at 1440 nm. The chiral ligand hybridized to the surface of achiral Cu2-x Se NPs by breaking the intrinsic symmetry of Cu2-x Se NPs and further large-scale assembly induced strong optical activity. The fabricated multilayer chiral membrane achieved an increased rectification ratio (RR) up to 114...
November 15, 2021: Angewandte Chemie
https://read.qxmd.com/read/34447854/liraglutide-improves-endothelial-function-via-the-mtor-signaling-pathway
#31
JOURNAL ARTICLE
Han Wu, Cheng Xiao, Yiting Zhao, Hongchao Yin, Miao Yu
BACKGROUND: Mammalian target of rapamycin (mTOR) is crucial for endothelial function. This study is aimed at assessing whether the glucagon-like peptide-1 (GLP-1) analogue liraglutide has a protective effect on endothelial function via the mTOR signaling pathway. METHODS: Human umbilical vein endothelial cells (HUVECs) were administered liraglutide (100 nM) for 0, 10, 30, 60, 720, and 1440 minutes, respectively. Then, the expression and phosphorylation levels of mTOR, mTOR-Raptor complex (mTORC1), and mTOR-Rictor complex (mTORC2) were determined by Western blot and immunoprecipitation, while mTORC1 and mTORC2 expression was blocked by siRNA-Raptor and siRNA-Rictor, respectively...
2021: Journal of Diabetes Research
https://read.qxmd.com/read/33582146/high-resolution-non-contrast-enhanced-magnetic-resonance-angiography-of-the-wrist-hand-and-digital-arteries-using-optimized-implementation-of-cartesian-quiescent-interval-slice-selective-qiss-at-1-5-t
#32
JOURNAL ARTICLE
Mona Salehi Ravesh, Annett Lebenatus, Alexandra Bonietzki, Johannes Hensler, Ioannis Koktzoglou, Robert R Edelman, Joachim Graessner, Olav Jansen, Marcus Both
PURPOSE: Non-contrast-enhanced (CE) magnetic resonance angiography (MRA) techniques are of considerable interest for diagnosing vascular diseases in the upper extremities owing to the possibility of repeated examinations, sufficient coverage of the measurement volume, and because possible side effects of administering iodine- or gadolinium-based contrast agents and radiation exposure can be avoided. The aim of this study was to investigate the feasibility of an optimized electrocardiogram (ECG) triggered Cartesian quiescent interval slice selective (QISS) technique for MRA of hand arteries...
May 2021: Magnetic Resonance Imaging
https://read.qxmd.com/read/33505068/raman-spectroscopy-based-characterization-of-cow-goat-and-buffalo-fats
#33
JOURNAL ARTICLE
M Saleem, Ayyaz Amin, Muhammad Irfan
In this study, Raman spectroscopy has been utilized to characterize buffalo, cow and goat fat samples by using laser wavelengths at 532 and 785 nm as excitation sources. It has been observed that Raman spectra of cow fats contain beta-carotene at 1006, 1156 and 1520 cm-1 , which are absent in buffalo and goat fats. The Raman bands at 1060, 1080, 1127 and 1440 cm-1 represent the saturated fatty acids, and their concentration is found relatively higher in buffalo fats than cow and goat. Similarly, the Raman band at 1650 cm-1 represent conjugated linoleic acid (CLA) which shows its relatively higher concentration in goat fats than cow and buffalo...
January 2021: Journal of Food Science and Technology
https://read.qxmd.com/read/33429975/determining-sonication-effect-on-e-coli-in-liquid-egg-egg-yolk-and-albumen-and-inspecting-structural-property-changes-by-near-infrared-spectra
#34
JOURNAL ARTICLE
David Nagy, Jozsef Felfoldi, Andrea Taczmanne Bruckner, Csilla Mohacsi-Farkas, Zsanett Bodor, Istvan Kertesz, Csaba Nemeth, Viktoria Zsom-Muha
In this study, liquid egg, albumen, and egg yolk were artificially inoculated with E. coli. Ultrasound equipment (20/40 kHz, 180/300 W; 30/45/60 min) with a circulation cooling system was used to lower the colony forming units (CFU) of E. coli samples. Frequency, absorbed power, energy dose, and duration of sonication showed a significant impact on E. coli with 0.5 log CFU/mL in albumen, 0.7 log CFU/mL in yolk and 0.5 log CFU/mL decrease at 40 kHz and 6.9 W absorbed power level. Significant linear correlation ( p < 0...
January 8, 2021: Sensors
https://read.qxmd.com/read/33411537/high-throughput-screening-and-automated-data-driven-analysis-of-the-triplet-photophysical-properties-of-structurally-diverse-heteroleptic-iridium-iii-complexes
#35
JOURNAL ARTICLE
Stephen DiLuzio, Velabo Mdluli, Timothy U Connell, Jacqueline Lewis, Victoria VanBenschoten, Stefan Bernhard
Steady state emission spectra and excited state lifetimes were measured for 1440 distinct heteroleptic [Ir(C^N)2 (N^N)]+ complexes prepared via combinatorial parallelized synthesis; 72% of the complexes were found to be luminescent, and the emission maxima of the library spanned the visible spectrum (652-459 nm). Spectral profiles ranged from broad structureless bands to narrow emissions exhibiting vibrational substructure. Measured excited state lifetimes ranged between ∼0.1-14 μs. Automated emission spectral fitting with successive Gaussian functions revealed four distinct measured classes of excited states; in addition to well understood metal-ligand to ligand-charge transfer (3 MLLCT) and ligand-centered (3 LC) excited states, our classification also identified photophysical characteristics of less explored mixed 3 MLLCT/3 LC states...
January 7, 2021: Journal of the American Chemical Society
https://read.qxmd.com/read/33390286/concentration-anisotropic-and-apparent-colour-effects-on-optical-reflectance-properties-of-virgin-and-ocean-harvested-plastics
#36
JOURNAL ARTICLE
Shungudzemwoyo P Garaba, Manuel Arias, Paolo Corradi, Tristan Harmel, Robin de Vries, Laurent Lebreton
We present reflectance measurements collected from virgin and ocean-harvested plastics. Virgin plastics included high and low density polyethylene (HDPE, LDPE), polypropylene (PP) as well as polystyrene (PS). Ocean-harvested plastics were ropes, sheets, foam, pellets and fragmented items previously trawled from the North Pacific Garbage Patch. Nadir viewing angles and plastic pixel coverage were varied to advance our understanding of how reflectance shape and magnitude can be influenced by these parameters...
March 15, 2021: Journal of Hazardous Materials
https://read.qxmd.com/read/33207869/three-dimensional-order-macroporous-ab-2-o-4-spinels-a-b-co-and-mn-as-electrodes-in-zn-air-batteries
#37
JOURNAL ARTICLE
José Béjar, Francisco Espinosa-Magaña, Minerva Guerra-Balcázar, Janet Ledesma-García, Lorena Álvarez-Contreras, Noé Arjona, Luis Gerardo Arriaga
In this work, atomically substituted three-dimensionally ordered macroporous (3DOM) spinels based on Co and Mn (MnCo2 O4 and CoMn2 O4 ) were synthetized and used as cathodic electrocatalysts in a primary Zn-air battery. Scanning/transmission electron microscopy images show a 3DOM structure for both materials. Skeleton sizes of 114.4 and 140.8 nm and surface areas of 65.3 and 74.6 m2 g-1 were found for MnCo2 O4 and CoMn2 O4 , respectively. The increase in surface area and higher presence of Mn3+ and Mn4+ species in the CoMn2 O4 3DOM material improved battery performance with a maximum power density of 101...
November 19, 2020: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/33149550/lung-cancer-combination-treatment-evaluation-of-the-synergistic-effect-of-cisplatin-prodrug-vinorelbine-and-retinoic-acid-when-co-encapsulated-in-a-multi-layered-nano-platform
#38
JOURNAL ARTICLE
Zhen Liang, Juan Li, Budong Zhu
PURPOSE: Lung cancer remains the leading cancer-associated deaths worldwide. Cisplatin (CIS) was often used in combination with other drugs for the treatment of non-small cell lung cancer (NSCLC). Prodrug is an effective strategy to improve the efficiency of drugs and reduce the toxicity. The aim of this study was to prepare and characterize CIS prodrug, vinorelbine (VNR), and all-trans retinoic acid (ATRA) co-delivered multi-layered nano-platform, evaluating their antitumor activity in vitro and in vivo...
2020: Drug Design, Development and Therapy
https://read.qxmd.com/read/33141354/efficacy-and-safety-of-1440-nm-nd-yag-laser-on-lower-face-and-neck-rejuvenation
#39
JOURNAL ARTICLE
Sayed Mandour, Rania Ahmed El-Tatawy, Ahmed F Alborgy, Sameh Elghamry
Reviewing the literatures, we did not found-to our knowledge-any study using the Nd:YAG laser with wavelength 1440 nm in assisted liposuction and rejuvenation of the head and neck region although of the higher absorption rate for fat and water. Evidence-based practice supports the benefits of laser-assisted liposuction over conventional liposuction with skin tightening in selected areas specifically the submental area and the neck. The aim of the work is to evaluate the efficacy and safety of Nd:YAG laser wavelength (WL) 1440 nm on lipolysis of submental area and skin tightening of the lower face and neck area...
August 2021: Lasers in Medical Science
https://read.qxmd.com/read/32804450/the-1440-nm-and-1927-nm-nonablative-fractional-diode-laser-current-trends-and-future-directions
#40
REVIEW
Paul M Friedman, Kristel D Polder, Pooja Sodha, Roy G Geronemus
Clinical characteristics of skin exposed to ultraviolet and infrared radiation include dryness, dyschromia, laxity, roughness, sallowness, scaling, telangiectasia, and wrinkles. Fractional photothermolysis promotes skin remodeling by formation of new dermal collagen. The nonablative fractional diode laser (NFDL) system employs fractional photothermolysis to rejuvenate the skin, using 2 distinct handpieces for wavelengths of 1440 nm and 1927 nm. Fractional photothermolysis from nonablative fractional diode lasers facilitates delivery of small molecular-weight compounds, such as L-ascorbic acid, through the skin without compromising barrier function of the stratum corneum...
August 1, 2020: Journal of Drugs in Dermatology: JDD
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