keyword
https://read.qxmd.com/read/38536873/quality-and-sustainability-of-ethiopia-s-national-surgical-indicators
#1
JOURNAL ARTICLE
Kayleigh R Cook, Zebenay B Zeleke, Ephrem Gebrehana, Daniel Burssa, Bantalem Yeshanew, Atkilt Michael, Yoseph Tediso, Taylor Jaraczewski, Chris Dodgion, Andualem Beyene, Katherine R Iverson
In 2015, the Ethiopian Federal Ministry of Health (FMOH) developed the Saving Lives through Safe Surgery (SaLTS) initiative to improve national surgical care. Previous work led to development and implementation of 15 surgical key performance indicators (KPIs) to standardize surgical data practices. The objective of this project is to investigate current practices of KPI data collection and assess quality to improve data management and strengthen surgical systems. The first portion of the study documented the surgical data collection process including methods, instruments, and effectiveness at 10 hospitals across 2 regions in Ethiopia...
2024: PLOS Glob Public Health
https://read.qxmd.com/read/38536864/sex-related-differences-in-pre-dialysis-trajectories-and-dialysis-initiation-a-french-nationwide-retrospective-study
#2
JOURNAL ARTICLE
Maxime Raffray, Louise Bourasseau, Cécile Vigneau, Cécile Couchoud, Clémence Béchade, François Glowacki, Sahar Bayat
BACKGROUND: In the last two decades, sex and gender differences have been documented in chronic kidney disease (CKD) management, including access to renal replacement therapy and its outcomes. The objectives of this study were to 1) compare the pre-dialysis healthcare utilization in men and women, and 2) examine the sex-specific factors associated with emergency dialysis start. METHODS: Adult patients with CKD who started dialysis in France in 2015 were extracted from the Renal Epidemiology and Information Network registry...
2024: PloS One
https://read.qxmd.com/read/38536830/association-of-anti-diabetic-drugs-and-covid-19-outcomes-in-patients-with-diabetes-mellitus-type-2-and-chronic-kidney-disease-nationwide-registry-analysis
#3
JOURNAL ARTICLE
Jelena Dimnjaković, Tamara Buble, Pero Ivanko, Tamara Poljičanin, Sandra Karanović Štambuk, Hana Brborović, Ognjen Brborović
INTRODUCTION: Patients with diabetes mellitus type 2 and chronic kidney disease (T2DM-CKD) have a 5 times higher risk of developing severe SARS-CoV-2 infection than those without these 2 diseases. The goal of this study is to provide information on T2DM-CKD and COVID-19 outcomes, with an emphasis on the association with anti-diabetic medications. METHODOLOGY: Study is designed as a retrospective cohort analysis covering the years 2020 and 2021. Data from the National Diabetes Registry (CroDiab) were linked to hospital data, primary healthcare data, Causes of Death Registry data, the SARS-CoV-2 vaccination database, and the SARS-CoV-2 test results database...
2024: PloS One
https://read.qxmd.com/read/38534803/incidence-of-non-melanoma-skin-cancers-in-salento-southern-italy-a-15-year-retrospective-analysis-from-the-cancer-registry-of-lecce
#4
JOURNAL ARTICLE
Emiliano Sordi, Prisco Piscitelli, Carla Albanese, Anna Melcarne, Anna Tardio, Fabrizio Quarta, Enrico Greco, Alessandro Miani, Andrea Falco, Elisabetta De Matteis, Maurizio Congedo, Adele Civino
BACKGROUND AND OBJECTIVES: Non-melanoma skin cancers (NMSCs) include basal cell carcinoma (BCC) and squamous-cell carcinoma (SCC), as well as a wide range of rare skin tumors. NMSCs is the most frequently diagnosed type of tumor among Caucasians. We aimed at estimating the incidence and mortality of NMSCs in the Salento area (Lecce province, Southern Italy), whose population is assumed to experience heavy and frequent sun exposure due to climatic/environmental factors, both for working and leisure activities...
December 21, 2023: Epidemiologia (Basel)
https://read.qxmd.com/read/38534135/chronic-rhinosinusitis-with-nasal-polyposis-and-biological-agents-the-aria-italy-survey
#5
JOURNAL ARTICLE
C Lombardi, G Passalacqua, F Menzella, R F Mauritz Canevari, G Danesi, A M Pusateri, M Carone, C Vancheri, F Di Marco, C Micheletto, G Manzotti, M Di Gioacchino, M B Bilò, M Gelardi, G Senna, G W Canonica
Background. Chronic rhinosinusitis (CRS) is an inflammatory disease that affects the nasal mucosa and the paranasal sinuses. CRS can be associated by nasal polyposis (CRSwNP phenotype) in up to 30% of patients and it is frequently associated with bronchial asthma. CRSwNP shows predominantly an underlying activation of type 2 inflammatory pathways with the involvement of eosinophils, IgE, interleukin (IL)-4, IL-5 and IL-13. Biological drugs that target these inflammatory cytokines are currently a therapeutic option recognized by guidelines for the treatment of uncontrolled form of the disease...
March 27, 2024: European Annals of Allergy and Clinical Immunology
https://read.qxmd.com/read/38533974/return-to-work-after-refractory-out-of-hospital-cardiac-arrest-in-patients-managed-with-or-without-extracorporeal-cardiopulmonary-resuscitation-a-nationwide-register-based-study
#6
JOURNAL ARTICLE
Emilie Gregers, Kristian Kragholm, Louise Linde, Sivagowry Rasalingam Mørk, Jo Bønding Andreasen, Christian Juhl Terkelsen, Jens Flensted Lassen, Jacob Eifer Møller, Helle Laugesen, Morten Smerup, Jesper Kjærgaard, Peter Hasse Møller-Sørensen, Lene Holmvang, Christian Torp-Pedersen, Christian Hassager, Helle Søholm
BACKGROUND: Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for refractory out-of-hospital cardiac arrest (OHCA). However, survivors managed with ECPR are at risk of poor functional status. The purpose of this study was to investigate return to work (RTW) after refractory OHCA. METHODS AND RESULTS: Of 44 360 patients with OHCA in the period of 2011 to 2020, this nationwide registry-based study included 805 patients with refractory OHCA in the working age (18-65 years) who were employed before OHCA (2% of the total OHCA cohort)...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533972/heart-rate-variability-deceleration-capacity-of-heart-rate-and-death-a-veteran-twins-study
#7
JOURNAL ARTICLE
Minxuan Huang, Amit J Shah, Rachel Lampert, Donald L Bliwise, Dayna A Johnson, Gari D Clifford, Richard Sloan, Jack Goldberg, Yi-An Ko, Giulia Da Poian, Erick A Perez-Alday, Zakaria Almuwaqqat, Anish Shah, Mariana Garcia, An Young, Kasra Moazzami, J Douglas Bremner, Viola Vaccarino
BACKGROUND: Autonomic function can be measured noninvasively using heart rate variability (HRV), which indexes overall sympathovagal balance. Deceleration capacity (DC) of heart rate is a more specific metric of vagal modulation. Higher values of these measures have been associated with reduced mortality risk primarily in patients with cardiovascular disease, but their significance in community samples is less clear. METHODS AND RESULTS: This prospective twin study followed 501 members from the VET (Vietnam Era Twin) registry...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533392/excess-deaths-in-china-during-sars-cov-2-viral-waves-in-2022-2023
#8
JOURNAL ARTICLE
Prabhat Jha, Patrick E Brown, Teresa Lam, Ed Morawski, Angus Reid
BACKGROUND: The extent to which the Omicron variant of SARS-CoV-2 raised death rates in China during its viral wave of December 2022-January 2023 remains largely undocumented. METHODS: We worked with an established national survey organization to survey 8,004 adults in all 31 administrative areas of China to ask about deaths in families since January 2020. We examined age-specific death rates, focusing on deaths above age 60 years, and at 15-59 years. We compared these to the United Nations (UN) estimates of age-specific mortality in 2019...
May 2024: Preventive Medicine Reports
https://read.qxmd.com/read/38533153/the-safety-profile-of-common-covid-19-vaccines-in-patients-with-multiple-sclerosis
#9
JOURNAL ARTICLE
Yasser S Aladdin, Danah A Alqarni, Sheifa W Alamoudi, Abdulrahman A Alharbi, Waad A Fudhah, Ghaida Alghamdi, Ahmed Attar
Background and objective Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). In light of the COVID-19 pandemic that emerged in late 2019, the World Health Organization (WHO) has endorsed mass immunization to enhance the population's immunity against the virus. However, certain concerns have been raised about the safety of COVID-19 vaccines among patients with autoimmune disorders, including those with multiple sclerosis (MS). Further research is required to address these concerns and to gain deeper insights into the possible complications of COVID-19 vaccines among MS patients...
February 2024: Curēus
https://read.qxmd.com/read/38533127/decoding-the-historical-tale-covid-19-impact-on-haematological-malignancy-patients-epicovideha-insights-from-2020-to-2022
#10
JOURNAL ARTICLE
Jon Salmanton-García, Francesco Marchesi, Francesca Farina, Barbora Weinbergerová, Federico Itri, Julio Dávila-Valls, Sonia Martín-Pérez, Andreas Glenthøj, Ditte Stampe Hersby, Maria Gomes da Silva, Raquel Nunes Rodrigues, Alberto López-García, Raúl Córdoba, Yavuz M Bilgin, Iker Falces-Romero, Shaimaa El-Ashwah, Ziad Emarah, Caroline Besson, Milena Kohn, Jaap Van Doesum, Emanuele Ammatuna, Monia Marchetti, Jorge Labrador, Giovanni Paolo Maria Zambrotta, Luisa Verga, Ozren Jaksic, Marcio Nucci, Klára Piukovics, Alba Cabirta-Touzón, Moraima Jiménez, Elena Arellano, Ildefonso Espigado, Ola Blennow, Anna Nordlander, Stef Meers, Jens van Praet, Tommaso Francesco Aiello, Carolina Garcia-Vidal, Nicola Fracchiolla, Mariarita Sciumè, Guldane Cengiz Seval, Pavel Žák, Caterina Buquicchio, Carlo Tascini, Stefanie K Gräfe, Martin Schönlein, Tatjana Adžić-Vukičević, Valentina Bonuomo, Chiara Cattaneo, Summiya Nizamuddin, Martin Čerňan, Gaëtan Plantefeve, Romane Prin, Tomas Szotkovski, Graham P Collins, Michelina Dargenio, Verena Petzer, Dominik Wolf, Natasha Čolović, Lucia Prezioso, Toni Valković, Francesco Passamonti, Gustavo-Adolfo Méndez, Uluhan Sili, Antonio Vena, Martina Bavastro, Alessandro Limongelli, Rafael F Duarte, Marie-Pierre Ledoux, Milche Cvetanoski, Zlate Stojanoski, Marina Machado, Josip Batinić, Gabriele Magliano, Monika M Biernat, Nikola Pantić, Christian Bjørn Poulsen, Annarosa Cuccaro, Maria Ilaria Del Principe, Austin Kulasekararaj, Irati Ormazabal-Vélez, Alessandro Busca, Fatih Demirkan, Marriyam Ijaz, Nikolai Klimko, Igor Stoma, Sofya Khostelidi, Noemí Fernández, Ali S Omrani, Rui Bergantim, Nick De Jonge, Guillemette Fouquet, Milan Navrátil, Ghaith Abu-Zeinah, Michail Samarkos, Johan Maertens, Cristina De Ramón, Anna Guidetti, Ferenc Magyari, Tomás José González-López, Tobias Lahmer, Olimpia Finizio, Natasha Ali, László Imre Pinczés, Esperanza Lavilla-Rubira, Alessandra Romano, Maria Merelli, Mario Delia, Maria Calbacho, Joseph Meletiadis, Darko Antić, José-Ángel Hernández-Rivas, Joyce Marques de Almeida, Murtadha Al-Khabori, Martin Hoenigl, Maria Chiara Tisi, Nina Khanna, Aleksandra Barać, Noha Eisa, Roberta Di Blasi, Raphaël Liévin, Carolina Miranda-Castillo, Nathan C Bahr, Sylvain Lamure, Mario Virgilio Papa, Ayel Yahya, Avinash Aujayeb, Jan Novák, Nurettin Erben, María Fernández-Galán, José-María Ribera-Santa Susana, Ikhwan Rinaldi, Rita Fazzi, Monica Piedimonte, Rémy Duléry, Yung Gonzaga, Andrés Soto-Silva, Giuseppe Sapienza, Alexandra Serris, Ľuboš Drgoňa, Ana Groh, Laura Serrano, Eleni Gavriilaki, Athanasios Tragiannidis, Juergen Prattes, Nicola Coppola, Vladimir Otašević, Miloš Mladenović, Mirjana Mitrović, Bojana Mišković, Pavel Jindra, Sofia Zompi, Maria Vittoria Sacchi, Carolin Krekeler, Maria Stefania Infante, Daniel García-Bordallo, Gökçe Melis Çolak, Jiří Mayer, Marietta Nygaard, Michaela Hanáková, Zdeněk Ráčil, Matteo Bonanni, Philipp Koehler, Laman Rahimli, Oliver A Cornely, Livio Pagano
BACKGROUND: The COVID-19 pandemic heightened risks for individuals with hematological malignancies due to compromised immune systems, leading to more severe outcomes and increased mortality. While interventions like vaccines, targeted antivirals, and monoclonal antibodies have been effective for the general population, their benefits for these patients may not be as pronounced. METHODS: The EPICOVIDEHA registry (National Clinical Trials Identifier, NCT04733729) gathers COVID-19 data from hematological malignancy patients since the pandemic's start worldwide...
May 2024: EClinicalMedicine
https://read.qxmd.com/read/38532943/left-atrial-appendage-occlusion-british-cardiovascular-intervention-society-and-british-heart-rhythm-society-position-statement
#11
REVIEW
Tim R Betts, Patrick A Calvert, Lee N Graham, Gerald J Clesham, Ashan Gunarathne, Brian Clapp, Dhiraj Gupta, Jan Kovac, James D Newton, David Hildick-Smith
Percutaneous left atrial appendage occlusion aims to reduce the risk of stroke in patients with AF, particularly those who are not good candidates for systemic anticoagulation. The procedure has been studied in large international randomised trials and registries and was approved by the National Institute for Health and Care Excellence in 2014 and by NHS England in 2018. This position statement summarises the evidence for left atrial appendage occlusion and presents the current indications. The options and consensus on best practice for pre-procedure planning, undertaking a safe and effective implant and appropriate post-procedure management and follow-up are described...
2024: Interventional Cardiology
https://read.qxmd.com/read/38532587/-incidence-of-postoperative-complications-in-chinese-patients-with-gastric-or-colorectal-cancer-based-on-a-national-multicenter-prospective-cohort-study
#12
JOURNAL ARTICLE
S Q Zhang, Z Q Wu, B W Huo, H N Xu, K Zhao, C Q Jing, F L Liu, J Yu, Z R Li, J Zhang, L Zang, H K Hao, C H Zheng, Y Li, L Fan, H Huang, P Liang, B Wu, J M Zhu, Z J Niu, L H Zhu, W Song, J You, S Yan, Z Y Li
Objective: To investigate the incidence of postoperative complications in Chinese patients with gastric or colorectal cancer, and to evaluate the risk factors for postoperative complications. Methods: This was a national, multicenter, prospective, registry-based, cohort study of data obtained from the database of the Prevalence of Abdominal Complications After Gastro- enterological Surgery (PACAGE) study sponsored by the China Gastrointestinal Cancer Surgical Union. The PACAGE database prospectively collected general demographic characteristics, protocols for perioperative treatment, and variables associated with postoperative complications in patients treated for gastric or colorectal cancer in 20 medical centers from December 2018 to December 2020...
March 25, 2024: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38532545/prediagnostic-use-of-menopausal-hormone-therapy-and-long-term-survival-of-localized-epithelial-ovarian-cancer-the-extreme-study
#13
JOURNAL ARTICLE
Alberte Hjorth Duus, Charlotte Gerd Hannibal, Louise Baandrup, Guoqiao Zheng, Michael Galanakis, Thomas Maltesen, Rasmus Hertzum-Larsen, Lina S Mørch, Susanne K Kjær
Use of menopausal hormone therapy (MHT) prior to an epithelial ovarian cancer (EOC) diagnosis has been suggested to be associated with improved survival. In a recent nationwide cohort study, we found that prediagnostic long-term MHT use, especially estrogen therapy (ET), was associated with improved long-term survival in women with nonlocalized EOC. Our aim was to investigate the influence of prediagnostic MHT use on long-term survival among women with localized EOC in the same nationwide study. Our study cohort comprised all women aged 50 years or older with an EOC diagnosis in Denmark 2000-2014 (n = 2097) identified from the Extreme study...
March 26, 2024: International Journal of Cancer. Journal International du Cancer
https://read.qxmd.com/read/38532450/lymphangioleiomyomatosis-in-patients-with-tuberous-sclerosis-a-national-centre-audit
#14
JOURNAL ARTICLE
Jan Johnson, Wendy Somerfield, Simon R Johnson
BACKGROUND: Lymphangioleiomyomatosis (LAM) is common in tuberous sclerosis complex (TSC) yet under recognised with management mostly based upon evidence obtained from patients with sporadic LAM. We performed a prospective audit of patients with TSC-LAM attending a national referral centre to inform management guidelines. METHODS: The UK LAM Centre was established in 2011 and conducts a prospective audit of pre-defined quality outcomes for all subjects. Audit data are reported on all patients with TSC-LAM and a comparator population of patients with sporadic LAM...
March 26, 2024: Orphanet Journal of Rare Diseases
https://read.qxmd.com/read/38532121/symptom-burden-and-relief-in-palliative-care-units-of-german-comprehensive-cancer-center-and-other-hospitals
#15
JOURNAL ARTICLE
Julia Berendt, Sarah Brunner, Maria Heckel, Mitra Tewes, Christoph Ostgathe, Susanne Gahr
PURPOSE: The National Hospice and Palliative Registry contains patient data from German hospice and palliative care facilities about symptoms. The aim of the study at hand is to differentiate symptom burden of patients in palliative care units between Comprehensive Cancer Center (CCC) and other hospitals regarding symptom burden and relief of patients in palliative care units. METHODS: The registry analysis provided data of patients in palliative care units (2014-2018)...
March 27, 2024: Journal of Cancer Research and Clinical Oncology
https://read.qxmd.com/read/38531863/how-comparable-are-patient-outcomes-in-the-real-world-with-populations-studied-in-pivotal-aml-trials
#16
JOURNAL ARTICLE
Ing Soo Tiong, Meaghan Wall, Ashish Bajel, Akash Kalro, Shaun Fleming, Andrew W Roberts, Nisha Thiagarajah, Chong Chyn Chua, Maya Latimer, David Yeung, Paula Marlton, Amanda Johnston, Anoop Enjeti, Chun Yew Fong, Gavin Cull, Stephen Larsen, Glen Kennedy, Anthony Schwarer, David Kipp, Sundra Ramanathan, Emma Verner, Campbell Tiley, Edward Morris, Uwe Hahn, John Moore, John Taper, Duncan Purtill, Pauline Warburton, William Stevenson, Nicholas Murphy, Peter Tan, Ashanka Beligaswatte, Howard Mutsando, Mark Hertzberg, Jake Shortt, Ferenc Szabo, Karin Dunne, Andrew H Wei
Despite an increasing desire to use historical cohorts as "synthetic" controls for new drug evaluation, limited data exist regarding the comparability of real-world outcomes to those in clinical trials. Governmental cancer data often lacks details on treatment, response, and molecular characterization of disease sub-groups. The Australasian Leukaemia and Lymphoma Group National Blood Cancer Registry (ALLG NBCR) includes source information on morphology, cytogenetics, flow cytometry, and molecular features linked to treatment received (including transplantation), response to treatment, relapse, and survival outcome...
March 26, 2024: Blood Cancer Journal
https://read.qxmd.com/read/38531266/prognostic-factors-for-relapse-in-patients-with-clinical-stage-i-testicular-non-seminoma-a-nationwide-population-based-cohort-study
#17
JOURNAL ARTICLE
Thomas Wagner, Birgitte Grønkær Toft, Jakob Lauritsen, Mikkel Bandak, Ib Jarle Christensen, Birte Engvad, Michael Kreiberg, Mads Agerbæk, Lars Dysager, Andreas Carus, Josephine Julie Rosenvilde, Daniel Berney, Gedske Daugaard
BACKGROUND: Approximately 30% of patients with clinical stage I non-seminoma (CSI-NS) relapse. Current risk stratification is based on lymphovascular invasion (LVI) alone. The extent to which additional tumor characteristics can improve risk prediction remains unclear. OBJECTIVE: To determine the most important prognostic factors for relapse in CSI-NS patients. DESIGN, SETTING, AND PARTICIPANTS: Population-based cohort study including all patients with CSI-NS diagnosed in Denmark between 2013 and 2018 with follow-up until 2022...
March 17, 2024: European Journal of Cancer
https://read.qxmd.com/read/38530293/shape-of-radiation-dose-response-relationship-for-ischaemic-heart-disease-mortality-and-its-interpretation-analysis-of-the-national-registry-for-radiation-workers-nrrw-cohort
#18
JOURNAL ARTICLE
Wei Zhang, Richard Ge Haylock, Michael Gillies, Nezahat Hunter
Statistically significant increases in ischemic heart disease (IHD) mortality with cumulative occupational external radiation dose were observed in the National Registry for Radiation Workers (NRRW) cohort. There were 174541 subjects in the NRRW cohort. The start of follow up was 1955, and the end of the follow-up for each worker was chosen as the earliest date of death or emigration, their 85th birthday or December 31, 2011. The dose-response relationship showed a downward curvature at a higher dose level > 0...
March 26, 2024: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://read.qxmd.com/read/38529902/a-comparison-of-cemented-femoral-fixation-via-anterior-versus-posterior-approach-total-hip-arthroplasty-an-analysis-of-60-739-total-hip-arthroplasties
#19
JOURNAL ARTICLE
Wayne Hoskins, Sophie Corfield, Yi Peng, Stephen E Graves, Roger Bingham
BACKGROUND: Anterior approach total hip arthroplasty (THA) decreases the rate of dislocation but increases femoral-sided complications in the way of periprosthetic fractures and component loosening. A cemented prosthesis may reduce femoral-sided complications and improve the risk:benefit profile of anterior approach THA. METHODS: Data from the Australian National Joint Replacement Registry were analysed for patients undergoing primary THA via the anterior or posterior approach using a cemented polished femoral stem from January 2015 to December 2021...
March 26, 2024: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://read.qxmd.com/read/38529890/the-prevalence-of-substance-use-disorders-among-people-in-norwegian-danish-and-swedish-prisons-a-multi-national-cohort-study-2010-19
#20
JOURNAL ARTICLE
Anne Bukten, Suvi Virtanen, Morten Hesse, Birgitte Thylstrup, Timo Lehmann Kvamme, Abdu Kedir Seid, Zheng Chang, Ingeborg Skjærvø, Torill Tverborgvik, Marianne R Stavseth
AIMS: We estimated the prevalence of substance use disorders (SUDs) in the Norwegian, Danish and Swedish prison populations and compared the prevalence of SUDs in the national prison populations with country-specific general population prevalence rates. DESIGN: A multi-national cohort study using data from the National Prison Registries linked to the National Patient Registries in Norway, Denmark and Sweden. SETTING AND PARTICIPANTS: We used data from the PriSUD-Nordic study, including national prison populations aged 19 years and older in Norway (2010-19), Denmark (2010-18) and Sweden (2010-13)...
March 26, 2024: Addiction
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