Yi-Xin Qiao, Yu Zhao, Li-Li Jiang
A 75-year-old male patient was hospitalized in hoarseness for 2 months. Laryngoscopy showed a mass protruding in right laryngeal chamber and covering the middle part of right vocal cord. Since tumor biopsy showed low differentiation cancer, he received total laryngectomy, and post-operative pathological result found composite carcinoma, which containing medium differentiated squamous cell carcinoma (about 5%) and low differentiated neuroendocrine carcinoma (about 95%). The growth status of tumor indicated it was collision carcinoma...
March 2020: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
Fang-Lan Li, Ming-Gang Su, Da-Zhi Shi, Fu-Ling Liang, Lin Li
Objective: To assess the staging, restaging, and treatment strategy determination of extranodal NK/T cell lymphoma (ENKT) by PET/CT real body (true whole-body, TWB) imaging, which is superior to PET/CT limitation of the whole body (limited whole-body, LWB, from skull vertex to upper thighs) by adding 'distal lower extremity' images. Methods: TWB 18 F-FDG PET/CT studies performed for staging and follow-up of ENKTL patients between January 2012 and September 2017 were retrospectively reviewed...
March 2020: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
Qiao-Yu He, Hui Hu, Bo Gao, Shu-Juan Yang, Ning-Xiu Li
Objective: To analyze the relationship between community social capital and quality of life among the middle-aged and elderly rural-to-urban residents, and to provide the policy reference for improving the health status. Methods: A multi-stage random sampling method was used to select the research objects. Univariate analysis and logistic regression model were used to explore the effect of social capital on quality of life among the middle-aged and elderly rural-to-urban urbanized residents...
March 2020: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
Cai-Xia Yan, Jia Li, Xin Shen, Li Luo, Yan Li, Ming-Yuan Li
Coronavirus disease 2019 (COVID-19) caused by the novel coronavirus, also known as severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), has become a Public Health Emergency of International Concern. Due to the large infection population, broad transmissibility and high mortality, it is urgent to find out the efficient and specific methods to prevent and treat COVID-19. As biological products have broadly applied in the prevention and treatment of severe epidemic diseases, they are promising in blocking novel coronavirus infection...
March 2020: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
Rong-Sheng Luan, Xin Wang, Xin Sun, Xing-Shu Chen, Tao Zhou, Quan-Hui Liu, Xin Lü, Xian-Ping Wu, Dong-Qing Gu, Ming-Shuang Tang, Hui-Jie Cui, Xue-Feng Shan, Jing Ouyang, Ben Zhang, Wei Zhang, Emergency Research Group Sichuan University Covid-
This review summarizes the ongoing researches regarding etiology, epidemiology, transmission dynamics, treatment, and prevention and control strategies of the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with comparison to severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV) and pandemic H1N1 virus. SARS-CoV-2 may be originated from bats, and the patients and asymptomatic carriers are the source of epidemic infection...
March 2020: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
Rebecca Boehm, Marlene B Schwartz, Ann Lowenfels, Ian Brissette, Mary Jo Pattison, Jia Ren
BACKGROUND: This study tested the hypothesis that written district wellness policies are associated with higher rates of implementation of nutrition and physical activity practices. METHODS: Written wellness policies and building level practices were assessed for schools (N = 295) within high-need districts (N = 70) in New York State. The relationship between policies and practices was measured using multi-level mixed-effects logistic regressions. RESULTS: Overall, stronger written district policies significantly increase the likelihood of practice implementation in schools...
March 27, 2020: Journal of School Health
Rhona Hurley, Arunachalam Iyer
The traditional aims of surgery for chronic otitis media have been to eliminate pathological tissue to produce a safe and dry ear; to prevent recurrent disease and if possible, to restore the normal function of the middle ear e.g. reconstructing the hearing mechanisms.
March 27, 2020: Clinical Otolaryngology
Fan Jiang, Chris Kubwimana, Julian Eaton, Hannah Kuper, Tess Bright
OBJECTIVE: Hearing loss can have far-reaching effects on social, emotional, and cognitive development, but few studies have addressed the link with mental health conditions. We conducted a systematic review of the association between hearing loss and mental health conditions in low-and middle-income countries (LMICs). METHODS: We searched six electronic databases using predetermined criteria to retrieve original research reporting mental health in people with hearing loss...
March 27, 2020: Tropical Medicine & International Health
Elshymaa A Abdelnaby
The present study aimed to evaluate the effect of a single intramuscular injection of melatonin on response of estrus, rate of conception, ovarian and uterine blood supply during the non-breeding season. Melatonin powder was dissolved in dimethyl sulfoxide (DMSO) and olive oil and injected in two dose of 25 mg (MEL-1; n = 10) and 50 mg (MEL-2; n = 10) in May. Ten ewes were served as the control (CON). Results showed that oestrus response was higher in the MEL- 2 group than in other groups (p < 0...
March 27, 2020: Reproduction in Domestic Animals
Paul Marx
Many observers have noticed the importance of anger in contemporary politics, particularly with reference to populism. This article addresses the question under which conditions people become angry about a specific aspect of their lives: their personal financial situation. Specifically, it asks if populist anti-elite rhetoric has a causal influence on anger and if this influence differs across socio-economic groups. The theoretical expectation is that anti-elite rhetoric allows people to externalize responsibility for an unfavorable financial situation and thereby to turn negative self-conscious emotions into anger...
March 27, 2020: British Journal of Sociology
Huihua Rao, Yanqiu Liu, Qing Lu, Ning Huang, Jihui Zhou
OBJECTIVE: To assess the value of combined chromosomal karyotyping and chromosomal microarray analysis (CMA) for prenatal diagnosis. METHODS: G-banding karyotyping and CMA were simultaneously performed on 546 women who were subjected to amniocentesis during middle pregnancy. RESULTS: In total 82 cases were detected with chromosomal abnormalities. The two methods were consistent in 43 cases, which included 14 trisomy 21, 6 trisomy 18, 1 trisomy 13, 14 sex chromosomal aneuploidies, 4 chromosomal deletions, 3 chromosomal duplications and 1 sex chromosomal mosaicism...
April 10, 2020: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
Behnaz Abiri, Mohsen Dehghani, Mohammadreza Vafa
Sarcopenia is the loss of muscle strength and muscle mass with aging and is one of the major risk factors for metabolic diseases. Cross-sectional studies have shown that vitamin D is associated with sarcopenia in both men and women. We investigated the effect of vitamin D supplementation over 12 weeks on muscle strength, muscle function, and body composition in middle-aged women in randomized double-blind placebo-controlled trial format. This revealed a significant difference in serum 25-hydroxyvitamin D levels between the intervention and placebo groups...
2020: Methods in Molecular Biology
S Asha Devi, S Abhijit
The neurotransmitter acetylcholine (ACh) is involved in memory and cognitive functions, which normally decline with age. In this chapter, we describe qRT-PCR and immunohistochemical protocols for measurement of muscarinic ACh receptor M1 (m1AChR) levels in the brains of middle-aged rats, with and without administration of grape seed proanthocyanidin extract (GSPE) and exercise training. The analyses revealed that the interventions led to an increase in m1AChR mRNA and protein levels in the CA1 subfield of hippocampus...
2020: Methods in Molecular Biology
Maria Lteif, Marylene Samia El Hayek, Hayat Azouri, Diane Antonios
Middle Eastern women seek frequently for self-adornment. Harmful effects of chemicals used in nail care services have involved women worldwide. This study was performed to determine Lebanese women's knowledge and attitudes toward adverse effects of compounds used in nail cosmetics. A national cross-sectional study was carried out using an online questionnaire and targeting women in Lebanon. Data was collected on sociodemographic characteristics, nail cosmetics' application, preventive measures, perceived knowledge and self-reported side effects associated with nail cosmetic's use...
March 26, 2020: Journal of Community Health
Philippe Lunetta, Pirkko Kriikku, Julius Tikka, Ilkka Ojanperä
We describe the sudden death of a middle-aged man while having a sauna under the influence of α-pyrrolidinovalerophenone (α-PVP) (PM blood concentration: 0.8 mg/L), amphetamine (0.34 mg/L), and other drugs (buprenorphine, benzodiazepines), and engaging in solitary sexual activities. The drugs' effects on the cardio-circulatory system and on body thermoregulation combined with the high temperatures are likely to have been central mechanisms leading to death. The high levels of adrenaline triggered by sexual arousal and the respiratory depression caused by buprenorphine, in association with benzodiazepines, may have also contributed to his death...
March 26, 2020: Forensic Science, Medicine, and Pathology
Jared N Schachner, Robert J Sampson
Highly skilled parents deploy distinct strategies to cultivate their children's development, but little is known about how parental cognitive skills interact with metropolitan opportunity structures and residential mobility to shape a major domain of inequality in children's lives: the neighborhood. We integrate multiple literatures to develop hypotheses on parental skill-based sorting by neighborhood socioeconomic status and public school test scores, which we test using an original follow-up of the Los Angeles Family and Neighborhood Survey...
March 26, 2020: Demography
Yanwu Sun, Xuejing Wu, Huiming Lin, Xingrong Lu, Ying Huang, Pan Chi
AIM: Currently, few studies have focused on the prognostic impact of lymph node regression to neoadjuvant chemoradiotherapy (NCRT) in rectal cancer. This study aimed to explore the prognostic impact of lymph node regression grade (LRG) in patients with locally advanced rectal cancer (LARC) following NCRT and radical surgery and develop a predictive nomogram for disease-free survival (DFS). METHODS: LARC patients undergoing NCRT and radical surgery between 2013 and 2014 were enrolled and divided into LRG low (≤ 2), middle (3-9), and high (≥ 10) groups...
March 26, 2020: Journal of Gastrointestinal Surgery
Juehan Wang, Bangjian Zhou, Xi Yang, Chunguang Zhou, Tingxian Ling, Bowen Hu, Yueming Song, Limin Liu
PURPOSE: To investigate airway development and airway resistance by computed tomographic three-dimensional (3D) reconstruction of the bronchial tree in patients with adolescent idiopathic scoliosis (AIS). We evaluated factors predicting postoperative respiratory complications to provide timely treatment, prevent complications, and improve operative and anesthetic safety. METHODS: From August 2015 to August 2017, 53 AIS patients with a mean age of 15.4 years (range 10-20 years) were included in this study...
March 26, 2020: European Spine Journal
Julia Koehn, Ruihao Wang, Carmen de Rojas Leal, Bernd Kallmünzer, Klemens Winder, Martin Köhrmann, Rainer Kollmar, Stefan Schwab, Max J Hilz
INTRODUCTION: Noninvasive temperature modulation by localized neck cooling might be desirable in the prehospital phase of acute hypoxic brain injuries. While combined head and neck cooling induces significant discomfort, peripheral vasoconstriction, and blood pressure increase, localized neck cooling more selectively targets blood vessels that supply the brain, spares thermal receptors of the face and skull, and might therefore cause less discomfort cardiovascular side effects compared to head- and neck cooling...
March 26, 2020: Neurological Sciences
Hossam S Alslaim, Andrew B Banooni, Ahmad Shaltaf, Nathan M Novotny
PURPOSE: Tracheoesophageal fistula (TEF) is a bellwether for a country's ability to care for sick newborns. We aim to review the existing literature from low- and middle-income countries in regard to management of those newborns and the possible approaches to improve their outcomes. METHODS: A review of the existing English literature was conducted with the aim of assessing challenges faced by providers in LMIC in terms of diagnostic, preoperative, operative and post-operative care for TEF patients...
March 26, 2020: Pediatric Surgery International
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