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JOURNAL ARTICLE
Fabio Perrotta, Vito D'Agnano, Domenica Francesca Mariniello, Giuseppe Castaldo, Maria Vitale, Mario Cazzola, Andrea Bianco, Filippo Scialò
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a debilitating and progressive lung disease of unknown aetiology, characterized by the relentless deposition of fibrotic tissue. Biomarkers may play a pivotal role as indicators of disease presence, progression, and treatment response. Sirtuins, a family of enzymes with ADP ribosyltransferase or deacetylase activity, have been implicated in several diseases, including pulmonary fibrosis. METHODS: A cross-sectional, prospective, observational single-center study was conducted to investigate the potential role of serum SIRTs levels as biomarkers in patients with IPF...
April 27, 2024: Respiratory Research
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JOURNAL ARTICLE
Carolina Fischer, Rainald Fischer, Anne-Marie Kirsten, Rolf Holle, Klaus Klütsch, Cosmina Stoleriu, Ralf Göres, Konrad Schultz, Kathrin Kahnert, Peter Alter, Dennis Nowak, Rudolf Jörres
INTRODUCTION: As with other chronic diseases, the course of chronic obstructive pulmonary disease (COPD) can be expected to be positively influenced if patients are well informed about their disease and undertake appropriate self-management. Assessments of the level of knowledge and management that are comparable should benefit from structured, systematically developed questionnaires. These, however, have not been published in Germany. METHODS: A total of 310 patients with COPD were recruited from three pneumological practices and one hospital to develop the questionnaires...
April 26, 2024: Pneumologie
#3
JOURNAL ARTICLE
Laura Vigil Giménez, Juana Martínez Llorens, Karina Portillo Carroz, Rocío García García, Francisco Ortega Ruiz, Luis Puente Maestu
INTRODUCTION: Following the SARS-CoV-2 pandemic in March 2020, pulmonary function testing (PFT) laboratories underwent a transformation, with a reduction in the number of tests or closure in some cases. The aim of this work was to know the activity of PFT in Spain and the modification of this activity due to the pandemic. MATERIAL AND METHODS: A protocolised survey was carried out to members of the PFT laboratories through the Spanish Society of Pneumology and Thoracic Surgery (SEPAR)...
2024: Open Respir Arch
#4
REVIEW
Hans-Jörg Busch, Sebastian Wolfrum, Guido Michels, Matthias Baumgärtel, Klaus-Friedrich Bodmann, Michael Buerke, Volker Burst, Philipp Enghard, Georg Ertl, Wolf Andreas Fach, Frank Hanses, Hans Jürgen Heppner, Carsten Hermes, Uwe Janssens, Stefan John, Christian Jung, Christian Karagiannidis, Michael Kiehl, Stefan Kluge, Alexander Koch, Matthias Kochanek, Peter Korsten, Philipp M Lepper, Martin Merkel, Ursula Müller-Werdan, Martin Neukirchen, Alexander Pfeil, Reimer Riessen, Wolfgang Rottbauer, Sebastian Schellong, Alexandra Scherg, Daniel Sedding, Katrin Singler, Marcus Thieme, Christian Trautwein, Carsten Willam, Karl Werdan
In Germany, physicians qualify for emergency medicine by combining a specialty medical training-e.g. internal medicine-with advanced training in emergency medicine according to the statutes of the State Chambers of Physicians largely based upon the Guideline Regulations on Specialty Training of the German Medical Association. Internal medicine and their associated subspecialities represent an important column of emergency medicine. For the internal medicine aspects of emergency medicine, this curriculum presents an overview of knowledge, skills (competence levels I-III) as well as behaviours and attitudes allowing for the best treatment of patients...
April 16, 2024: Medizinische Klinik, Intensivmedizin und Notfallmedizin
#5
REVIEW
Melpomeni Bizhga, Virtut Velmishi, Lorena Sila, Albert Koja, Stiljan Hoxha
Dysphagia lusoria is a rare pediatric condition caused by extrinsic compression of the esophagus by an abnormal subclavian artery. The most common congenital abnormality in aortic arch development is an aberrant right subclavian artery. The retroesophageal right subclavian artery is typically symptomatic in 10-33% of cases. The patient, an 8-month-old girl with a history of early dysphagia and stridor, was diagnosed with an abnormal right subclavian artery. She was admitted to the pneumology service multiple times due to stridor, vomiting, and failure to thrive...
April 16, 2024: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
#6
JOURNAL ARTICLE
Eva-Maria Skiba, Karl Philipp Drewitz, Ivonne Panchyrz, Stefanie Deckert, Christian Apfelbacher, Katharina Piontek
After acute infection with the SARS-CoV-2 virus, up to 10 % of affected individuals suffer from long-term health impairments, also referred to as "Post-COVID". In Germany, specialized outpatient clinics have been established to care for patients with Post-COVID. A structured survey of the care situation is not yet available, but essential for a demand-oriented care. The present study aimed to systematically assess and describe structural and process-related aspects of care, and to perform an inventory and needs analysis of Post-COVID outpatient clinics in Germany...
April 2024: Deutsche Medizinische Wochenschrift
#7
JOURNAL ARTICLE
Sebastiaan De Keersmaecker, Sofie Van Cauter, Kim Bekelaar
In this case report, we describe a 76-year-old woman, presenting with dizziness for the past 2 months, without other focal neurological signs. A magnetic resonance imaging of the brain was ordered by her GP. The MRI demonstrated multiple ring-enhancing lesions, both supratentorial and infratentorial. Lumbar puncture showed normal findings, in particular a normal cell count and culture. Because of the radiologic appearance, initially thought to be suggestive of cerebral abscesses, antibiotics were started. However, further workup revealed a new diagnosis of a stage IV (metastatic) small cell lung carcinoma, making diffuse brain metastases more likely...
April 1, 2024: Topics in Magnetic Resonance Imaging: TMRI
#8
JOURNAL ARTICLE
Daniela Oatis, Hildegard Herman, Cornel Balta, Alina Ciceu, Erika Simon-Repolski, Alin Gabriel Mihu, Caterina Claudia Lepre, Marina Russo, Maria Consiglia Trotta, Antonietta Gerarda Gravina, Michele D'Amico, Anca Hermenean
INTRODUCTION: The pathogenesis of post-COVID interstitial lung disease, marked by lung tissue scarring and functional decline, remains largely unknown. OBJECTIVES: We aimed to elucidate the temporal cytokine/chemokine changes in bronchoalveolar lavage (BAL) from patients with post-COVID interstitial lung disease to uncover potential immune drivers of pulmonary complications. DESIGN: We evaluated 16 females diagnosed with post-COVID interstitial lung disease, originating from moderate to severe cases during the second epidemic wave in the Autumn of 2020, treated at the Pneumology Department of the Arad County Clinical Hospital, Romania...
2024: Therapeutic Advances in Chronic Disease
#9
JOURNAL ARTICLE
Valentino Allocca, Luca Guidelli, Angela Galgano, Lucia Benedetti, Roberto Fabbroni, Andrea Bianco, Piero Paladini, Raffaele Scala
INTRODUCTION: Medical pleuroscopy (MP) is an invasive technique that provides access to the pleural space with a rigid or semi-rigid work instrument, allowing for visualization and the obtaining of bioptic pleural samples. Using pulmonologist-based analgosedation to perform pleuroscopy is still debated for safety reasons. The aim of this real-life study is to demonstrate the safety and diagnostic yield of MP performed under balanced analgosedation by a pulmonologist team with expertise in the management of critically ill patients in the respiratory intensive care unit (RICU) and interventional pulmonology unit as compared to video-assisted thoracic surgery (VATS) performed by a thoracic surgeon team under anesthesiologist-based analgosedation...
March 7, 2024: Diagnostics
#10
EDITORIAL
Krzysztof Kuziemski, Monika Franczuk, Sebastian Majewski, Tadeusz M Zielonka, Adam Barczyk
Advances in Respiratory Medicine , which has been published by MDPI since 2022, serves as a platform for hosting pneumological studies [...].
March 19, 2024: Advances in Respiratory Medicine
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JOURNAL ARTICLE
Kaid Darwiche, Winfried Randerath, Ralf-Harto Hübner, Markus Rathmayer, Melanie Tiefgraber, Volkmar Borass, Anne Piening, Lars Hagmeyer, Juergen Hetzel, Ralf Eberhardt, Wolfgang Gesierich, Markus Unnewehr, Sebastian Boeing, Michael Wilke, Felix Herth, Torsten Bauer
INTRODUCTION: The ambulantization of patient care that were previously provided as inpatient service is one of the goals of the current reform in the German healthcare system. In pulmonology, this particularly applies to endoscopic procedures. However, the real costs of endoscopic services, which form the basis for the calculation of a future so called hybrid DRG or in the AOP catalog, are unclear. METHODS: After selection of use cases including endoscopic procedures which can be performed on an outpatient basis by a committee of experts the appropriate DRGs were identified from the § 21-KHEntgG data for 2022 published by the Institute for the Hospital Remuneration System (InEK)...
March 20, 2024: Pneumologie
#12
JOURNAL ARTICLE
Sergio García-Martín, Víctor M Mora-Cuesta, Sara Naranjo-Gozalo, Jose Javier Jiménez-Velasco, María Pía Roiz-Mesones, Victor Fernández-Lobo
No abstract text is available yet for this article.
March 11, 2024: Progress in Transplantation
#13
JOURNAL ARTICLE
Laura Licchetta, Giulia Bruschi, Carlotta Stipa, Laura Maria Beatrice Belotti, Lorenzo Ferri, Barbara Mostacci, Luca Vignatelli, Raffaella Minardi, Lidia Di Vito, Lorenzo Muccioli, Antonella Boni, Paolo Tinuper, Francesca Bisulli
OBJECTIVE: Typically diagnosed in early childhood or adolescence, TSC is a chronic, multisystemic disorder with age-dependent manifestations posing a challenge for transition and for specific surveillance throughout the lifetime. Data on the clinical features and severity of TSC in adults and on the prognosis of epilepsy are scarce. We analyzed the clinical and genetic features of a cohort of adult patients with TSC, to identify the prognostic predictors of seizure remission after a long follow-up...
February 29, 2024: Epilepsy & Behavior: E&B
#14
JOURNAL ARTICLE
Marcus Joest, Johanna Klein, Daniel Kütting, Dirk Skowasch
Allergic bronchopulmonary aspergillosis (ABPA) is a regular occurrence in everyday pneumology. ABPA should be considered in patients with severe asthma, in mould allergic patients with very high serum IgE levels and in patients with cystic fibrosis. The aim should be to make the diagnosis as early as possible in the course of the disease to avoid late complications such as bronchiectasis and fibrotic lung remodelling. Symptoms are highly variable and rather non-specific, overlapping with those of the underlying primary disease...
March 2024: Pneumologie
#15
JOURNAL ARTICLE
Dominic Dellweg, Georg Nilius, Achim Grünewaldt, Andreas Günther, Matthias Held, Martin Hetzel, Andreas Schlesinger, Robin Schlott, Georgios Sofianos, Markus Unnewehr, Thomas Voshaar, Winfried Randerath
Acute dyspnoea is one of the most common internal medicine symptoms in the emergency department. It arises from an acute illness or from the exacerbation of a chronic illness. Symptom-related emergency structures and corresponding structural guidelines already exist in the stroke and chest pain units for dealing with the leading symptoms of acute stroke and acute chest pain. These are lacking in Germany for the key symptom of dyspnoea, although the benefits of these structures have already been proven in other countries...
February 21, 2024: Pneumologie
#16
JOURNAL ARTICLE
Carlos Rábade-Castedo, Carlos Zamarrón-Sanz, Álvaro Hermida-Ameijeiras, Romina Abelleira-Paris, Ana Casal-Mouriño, Lucia Ferreiro-Fernández, Nuria Rodríguez-Núñez, Jorge Ricoy-Gabaldón, María Elena Toubes-Navarro, José Manuel Álvarez-Dobaño, Luis Valdés-Cuadrado
INTRODUCTION: The smoker's narrative during smoking quitting provides insight into aspects not fully explored in daily clinical practice. The aim of the study was to analyze the smoker narrative using two types of methodologies: content analysis and grounded theory, before and after smoking cessation intervention, provided to the smoker in a specialized Smoking Cessation Unit accredited by the Spanish Society of Pneumology and Thoracic Surgery. METHODS: A prospective observational study of current smokers included in a tobacco cessation program between 2017 and 2020 was conducted at the Smoking Cessation Unit of Santiago de Compostela Health Area, Spain...
2024: Tobacco Induced Diseases
#17
JOURNAL ARTICLE
Erich Stoelben
Idiopathic subglottic stenosis is a circular scarred narrowing of the airway at the transition from the cricoid cartilage to the trachea. The stenosis is found radiologically and endoscopically at the level of the cricoid cartilage without involvement of the cricoid or tracheal cartilage itself. The disease practically only affects women between the ages of 20 and 60. The same clinical picture occurs in granulomatosis with polyangiitis and less frequently in other autoimmune diseases, where it requires systemic treatment...
February 15, 2024: Zentralblatt Für Chirurgie
#18
JOURNAL ARTICLE
Fares Dashti, Ian Gregory
No abstract text is available yet for this article.
February 2024: Clinical and Experimental Allergy
#19
JOURNAL ARTICLE
Luca Pio, Valerio Gentilino, Francesco Macchini, Alberto Attilio Scarpa, Roberto Lo Piccolo, Andrea Conforti, Alberto Ratta, Riccardo Guanà, Francesco Molinaro, Sara Costanzo, Giovanna Riccipetitoni, Gabriele Lisi, Paola Midrio, Francesca Tocchioni, Giovannii Cobellis, Andrea Volpe, Elisa Zolpi, Anna Morandi, Enrico Ciardini, Claudio Vella, Maria Giovanna Grella, Maria Sergio, Edoardo Guida, Lorenzo Nanni, Silvia Ceccanti, Vincenzo Di Benedetto, Maurizio Cheli, Alfredo Garzi, Maria Nobili, Valeria Gabriele, Giovanni Boroni, Filippo Incerti, Nicola Zampieri, Sebastiano Cacciaguerra, Pier Luca Ceccarelli, Maria Escolino, Vito Briganti, Davide Gori, Ciro Esposito, Piergiorgio Gamba, Fabrizio Gennari, Alessandro Inserra, Patrizia Dall'Igna, Carmelo Romeo, Pietro Bagolan, Cosimo Bleve, Fabio Chiarenza, Francesco Morini, Gloria Pelizzo, Michele Torre
INTRODUCTION: Over the years, congenital lung malformations (CLM) management remains a controversial topic in pediatric thoracic surgery. The Italian Society of Pediatric Surgery performed a national survey to study the current management variability among centers, trying to define national guidelines and a standardized approach of children with congenital lung malformations. METHODS: Following a National Society approval, an electronic survey including 35 items on post-natal management was designed, focusing on surgical, anesthesiology, radiology and pneumology aspects...
February 10, 2024: Pediatric Surgery International
#20
REVIEW
Ivana Besenji, Léon Genecand, Pieter-Jan Gijs, Stéphane Mouraux, John David Aubert
In this review of new developments in pulmonology for the year 2023, we look at two contributions in the diagnostic field: the optimal way of comparing a spirometry measurement with the expected normal values, and a new tool for identifying dysfunctional breathing. On the therapeutic front, a new molecule, ensifentrine, has been shown to be effective in a phase 3 study involving COPD patients. Finally, and still for patients with severe COPD, volume reduction, either surgically or endoscopically, can lead to an improvement in function and severity scores...
January 31, 2024: Revue Médicale Suisse
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