Salma M Bakr, Ajay Patel, Mohamed A Zaazoue, Kathryn Wagner, Sandi K Lam, Daniel J Curry, Jeffrey S Raskin
OBJECTIVE: The grid-based orthogonal placement of depth electrodes (DEs), initially defined by Jean Talairach and Jean Bancaud, is known as stereo-electroencephalography (sEEG). Although acceptance in the United States was initially slow, advances in imaging and technology have spawned a proliferation of North American epilepsy centers offering sEEG. Despite publications highlighting minimal access techniques and varied indications, standard work for phase I targeted DE has not been defined...
January 22, 2021: Journal of Neurosurgery. Pediatrics
Keerat Rai Ahuja, Salik Nazir, Vardhmaan Jain, Toshiaki Isogai, Anas M Saad, Beni R Verma, Shashank Shekhar, Ravi Kumar, Ehab A Eltahawy, John E Madias
BACKGROUND: Previous small-scale studies have reported conflicting findings regarding the prevalence of diabetes mellitus (DM) and its association with outcomes in patients with takotsubo syndrome (TTS) OBJECTIVE: We sought to assess the prevalence of DM and its association with outcomes in TTS patients. METHODS: Nationwide inpatient sample (NIS) was queried to extract patient information from January 1, 2009 to September 30, 2015. Propensity score matching (PSM) was done to compare mortality and other in-hospital outcomes...
January 19, 2021: Heart & Lung: the Journal of Critical Care
Emad Barsoum, Sherif Elhosseiny, Brijesh Patel, Sankalp Pathak, Ankitkumar Patel, Pranaychandra Vaidya
Reverse Takotsubo Cardiomyopathy (rTTC) is a rare variant of Takotsubo Cardiomyopathy (TTC) that is characterized by hypokinesis of the base and sparing of the mid to apical wall of the left ventricle best seen on echocardiogram. Intracranial hemorrhage (ICH) has been identified as a risk factor rTTC. Nearly around 10% of the patients with TTC develop cardiogenic shock. We hereby report the successful use of the Impella Ventricular Assist Device (Impella CP®) for management of rTTC in the setting of acute ICH...
January 19, 2021: Heart & Lung: the Journal of Critical Care
Tufan Çınar, Mert İlker Hayıroğlu, Vedat Çiçek, Şahhan Kılıç, Süha Asal, Samet Yavuz, Murat Selçuk, Emre Yalçınkaya, Nurgül Keser, Ahmet Lütfullah Orhan
BACKGROUND: This study examined the possible association between the prognostic nutritional index (PNI) and in-hospital mortality rates in cases with a high cardiovascular risk burden and hospitalized with the diagnosis of coronavirus disease 2019 (COVID-19). MATERIAL AND METHODS: This retrospective and cross-sectional study included 294 COVID-19 patients hospitalized in a tertiary referral pandemic center. The study cohort was grouped into tertiles based on the initial PNI values as T1, T2, and T3...
January 13, 2021: Heart & Lung: the Journal of Critical Care
Monika Tukacs, Kenrick D Cato
No abstract text is available yet for this article.
January 19, 2021: Heart & Lung: the Journal of Critical Care
Saeed Shoar
No abstract text is available yet for this article.
January 12, 2021: Heart & Lung: the Journal of Critical Care
Cindy L Munro, Zhan Liang, Ming Ji, Maya N Elías, Xusheng Chen, Karel Calero, E Wesley Ely
Delirium in the intensive care unit (ICU) affects up to 80% of critically ill, mechanically ventilated (MV) adults. Delirium is associated with substantial negative outcomes, including increased hospital complications and long-term effects on cognition and health status in ICU survivors. The purpose of this randomized controlled trial is to test the effectiveness of a Family Automated Voice Reorientation (FAVoR) intervention on delirium among critically ill MV patients. The FAVoR intervention uses scripted audio messages, which are recorded by the patient's family and played at hourly intervals during daytime hours...
January 19, 2021: Contemporary Clinical Trials
Tracey E McMillan, Sarah Austin, Kristiina Hyrkas
In the United States, the number of deaths related to overdose of heroin and other opioids, specifically among women of reproductive age, has been rising. This case report adds new knowledge to the limited scientific literature currently available. We describe the care of a 30-year-old pregnant (31.4 weeks gestation) woman who was found unresponsive from a suspected opioid overdose in a friend's home. In response to an unwitnessed cardiopulmonary arrest, the team initiated therapeutic hypothermia 12 hours after the event...
January 19, 2021: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
Roy Spijkerman, Nikita Kn Jorritsma, Suzanne H Bongers, Bas Jj Bindels, Bernard N Jukema, Lillian Hesselink, Falco Hietbrink, Luke Ph Leenen, Harriët Mr van Goor, N Vrisekoop, Karin Ah Kaasjager, Leo Koenderman
OBJECTIVES: A high incidence of pulmonary embolism (PE) is reported in patients with critical Corona Virus Disease 2019 (COVID-19). Neutrophils may contribute to this through a process referred to as immunothrombosis. The aim of this study was to investigate the occurrence of neutrophil subpopulations in blood preceding the development of COVID-19 associated PE. METHODS: We studied COVID-19 patients admitted to the ICU of our tertiary hospital between 19-03-2020 and 17-05-2020...
January 22, 2021: Scandinavian Journal of Immunology
Tung-Lin Tsui, Ya-Ting Huang, Wei-Chih Kan, Mao-Sheng Huang, Min-Yu Lai, Kwo-Chang Ueng, Chih-Chung Shiao
BACKGROUND: Procalcitonin (PCT) has been widely investigated as an infection biomarker. The study aimed to prove that serum PCT, combining with other relevant variables, has an even better sepsis-detecting ability in critically ill patients. METHODS: We conducted a retrospective cohort study in a regional teaching hospital enrolling eligible patients admitted to intensive care units (ICU) between July 1, 2016, and December 31, 2016, and followed them until March 31, 2017...
2021: PloS One
Dennis J Zheng, Patrick J Sur, Mary Goretty Ariokot, Catherine Juillard, Mary Margaret Ajiko, Rochelle A Dicker
Trauma is a leading cause of morbidity and mortality worldwide. Data characterizing the burden of injury in rural Uganda is limited. Hospital-based trauma registries are a critical tool in illustrating injury patterns and clinical outcomes. This study aims to characterize the traumatic injuries presenting to Soroti Regional Referral Hospital (SRRH) in order to identify opportunities for quality improvement and policy development. From October 2016 to July 2019, we prospectively captured data on injured patients using a locally designed, context-relevant trauma registry instrument...
2021: PloS One
Andrey Eliseyev, Ian Jerome Gonzales, Anh Le, Kevin Doyle, Jennifer Egbebike, Angela Velazquez, Sachin Agarwal, David Roh, Soojin Park, E Sander Connolly, Jan Claassen
OBJECTIVE: Behaviorally unresponsive patients in intensive care units (ICU) are unable to consistently and effectively communicate their most fundamental physical needs. Brain-Computer Interface (BCI) technology has been established in the clinical context, but faces challenges in the critical care environment. Contrary to cue-based BCIs, which allow activation only during pre-determined periods of time, self-paced BCI systems empower patients to interact with others at any time. The study aims to develop a self-paced BCI for patients in the intensive care unit...
2021: PloS One
Matt J Keeling, Edward M Hill, Erin E Gorsich, Bridget Penman, Glen Guyver-Fletcher, Alex Holmes, Trystan Leng, Hector McKimm, Massimiliano Tamborrino, Louise Dyson, Michael J Tildesley
Efforts to suppress transmission of SARS-CoV-2 in the UK have seen non-pharmaceutical interventions being invoked. The most severe measures to date include all restaurants, pubs and cafes being ordered to close on 20th March, followed by a "stay at home" order on the 23rd March and the closure of all non-essential retail outlets for an indefinite period. Government agencies are presently analysing how best to develop an exit strategy from these measures and to determine how the epidemic may progress once measures are lifted...
January 22, 2021: PLoS Computational Biology
Julianne S Oktay, Elizabeth A Rohan, Karen Burruss, Christine Callahan, Tara J Schapmire, Brad Zebrack
BACKGROUND/PURPOSE: There is much interest in screening for and treating psychosocial distress in cancer patients; however, little is known about if and how psychosocial services are provided for patients demonstrating significant levels of distress. Oncology social workers (OSWs) are the primary providers of psychosocial care for cancer patients and their families, yet there is no widely-used and empirically-validated instrument that captures the range of interventions provided by OSWs...
December 17, 2020: Journal of Psychosocial Oncology
William Schleif, Frances Hamblin, Allen D Everett, Ernest M Graham, Jennifer Cross, Christy Fernald, Robert Follett, Bryan Lopes, Denise Martinez, Hector Monforte, Jennifer Ross-Wilkinson, Austin Sellers, Sandra Brooks
Repurposing biological samples collected for required diagnostic purposes into suitable biobanking projects is a particularly useful method for enabling research in vulnerable populations. This approach is especially appropriate for the neonate in the neonatal intensive care unit (NICU), where blood volume reductions can quickly increase beyond minimal risk for adverse events, such as iatrogenic anemia, and proxy consent provided by parents or guardians is required. The method described in this study provides a framework to prospectively collect and store blood-derived clinical samples after all clinical and regulatory requirements are fulfilled...
January 21, 2021: Biopreservation and Biobanking
Wynne E Morrison
No abstract text is available yet for this article.
January 22, 2021: Pediatric Critical Care Medicine
Carolyn M Rutledge, Jennifer O'Rourke, Anne M Mason, Katherine Chike-Harris, Lyn Behnke, Lolita Melhado, Loureen Downes, Tina Gustin
BACKGROUND: Telehealth is a rapidly growing health care delivery modality with advanced practice nurses as key providers. This growth has occurred without critical consideration of provider training. Training requires the development of competencies situated within a framework. PROBLEM: Standardized telehealth competencies for advanced practice nursing are missing. The purpose of this article is to describe the development of telehealth competencies for education and practice...
January 19, 2021: Nurse Educator
Jérémie Joffre, Elliot Lloyd, Erika Wong, Che Chung-Yeh, Nina Nguyen, Fenguyn Xu, Matthieu Legrand, Judith Hellman
OBJECTIVES: Catecholaminergic vasopressors are the cornerstone of circulatory shock management. Nevertheless, catecholamines have problematic side effects, arousing a growing interest in noncatecholaminergic agents such as vasopressin or angiotensin-II. However, their respective effects on sepsis-associated microvascular endothelial dysfunction such as permeability or inflammation remain elusive. We investigated the role of catecholamines and other vasopressors on Toll-like receptor agonists-induced microvascular endothelial permeability and inflammation...
January 22, 2021: Critical Care Medicine
James M Wright, Christina Gerges, Berje Shammassian, Collin M Labak, Eric Z Herring, Benjamin Miller, Ayham Alkhachroum, Mohan Kottapally, Christina Huang Wright, Richard B Rodgers, Cara Sedney, Laura B Ngwenya, Martina Stippler, Emily Sieg, Maya A Babu, Alan Hoffer, Rana Hejal
OBJECTIVES: Prone positioning has been shown to be a beneficial adjunctive supportive measure for patients who develop acute respiratory distress syndrome. Studies have excluded patients with reduced intracranial compliance, whereby patients with concomitant neurologic diagnoses and acute respiratory distress syndrome have no defined treatment algorithm or recommendations for management. In this study, we aim to determine the safety and feasibility of prone positioning in the neurologically ill patients...
January 22, 2021: Critical Care Medicine
Eric E Chinaeke, Bryan L Love, Joe Magagnoli, Ismaeel Yunusa, Gene Reeder
OBJECTIVE: To evaluate the impact of pre-intensive care unit admission (pre-ICU) statin use on all-cause in-hospital mortality and ICU length of stay (LOS). DESIGN: Retrospective cohort study. SETTING: Adult ICUs at tertiary hospitals. PATIENTS: Adult critically ill patients diagnosed with sepsis admitted to the ICUs. INTERVENTION: The exposure was pre-ICU statin prescription (statin users); unexposed represented absence of pre-ICU prescription (non-users)...
January 22, 2021: Pharmacotherapy
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