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Keywords Metastatic adenocarcinomas inv...

Metastatic adenocarcinomas involving duodenum

https://read.qxmd.com/read/17451216/melena-a-rare-complication-of-duodenal-metastases-from-primary-carcinoma-of-the-lung
#21
JOURNAL ARTICLE
Chrysoula Kostakou, Lubna Khaldi, Andrew Flossos, Andreas N Kapsoritakis, Spiros P Potamianos
Small bowel metastases from primary carcinoma of the lung are very uncommon and occur usually in patients with terminal stage disease. These metastases are usually asymptomatic, but may present as perforation, obstruction, malabsorption, or hemorrhage. Hemorrhage as a first presentation of small bowel metastases is extremely rare and is related to very poor patient survival. We describe a case of a 61- year old patient with primary adenocarcinoma of the lung, presenting with melena as the first manifestation of small bowel metastasis...
February 28, 2007: World Journal of Gastroenterology: WJG
https://read.qxmd.com/read/12578411/duodenal-preserving-resection-of-the-head-of-the-pancreas-and-pancreatic-head-resection-with-second-portion-duodenectomy-for-benign-lesions-low-grade-malignancies-and-early-carcinoma-involving-the-periampullary-region
#22
JOURNAL ARTICLE
Young-Joon Ahn, Sun-Whe Kim, Youn-Chan Park, Jin-Young Jang, Yoo-Seok Yoon, Yong-Hyun Park
HYPOTHESIS: Duodenal-preserving resection of the head of the pancreas (DPRHP) and pancreas head resection with segmental duodenectomy (PHRSD) can be alternatives to standard pancreaticoduodenectomy for benign periampullary lesions. DESIGN: Retrospective analysis of patients requiring surgery for benign and borderline malignant tumors of the periampullary region. SETTING: Tertiary care referral center. PATIENTS: Duodenal-preserving resection of the head of the pancreas (n = 8) and PHRSD (n = 7) were performed in 15 patients with a preoperative diagnosis of benign and borderline malignant tumors of the periampullary region (ie, 11 pancreas head lesions [2 intraductal papillary mucinous tumors, 4 serous cystadenomas, 2 insulinomas, 1 epidermal cyst, 1 metastatic renal cell carcinoma, 1 nonfunctioning islet cell tumor/parapaillary] and 4 duodenal lesions [3 adenomas and 1 adenocarcinoma])...
February 2003: Archives of Surgery
https://read.qxmd.com/read/11908834/canine-gastric-adenocarcinoma-and-leiomyosarcoma-a-retrospective-study-of-21-cases-1986-1999-and-literature-review
#23
REVIEW
Heather M Swann, David E Holt
This retrospective study describes the clinical course, treatment, and outcome of 21 dogs with gastric adenocarcinomas (n=19) and leiomyosarcomas (n=2). Medical records from 1986 to 1999 were reviewed for signalment, weight, diagnosis, tumor location, clinical signs, radiographic imaging procedures, surgical procedures, chemotherapy, duration of follow-up monitoring, outcome, cause of death, metastatic rate, metastatic sites, and method of detection of metastasis. Fourteen of 19 (74%) dogs with gastric adenocarcinomas had metastasis...
March 2002: Journal of the American Animal Hospital Association
https://read.qxmd.com/read/11490822/long-term-survival-after-surgical-resection-for-pancreatic-cancer
#24
JOURNAL ARTICLE
K Yoshizawa, H Nagai, K Kurihara, N Sata, T Kawai, K Saito
BACKGROUND/AIMS: Pancreatic cancer remains one of the most formidable tumors defying early detection and effective treatment. Long-term survivors, however, do exist after resection. We investigated the clinicopathologic features of patients with pancreatic cancer who survived more than 5 years to draw out some suggestions concerning the indication of surgical treatment. METHODOLOGY: We studied the clinicopathologic features of 13 patients with pancreatic cancer who survived more than 5 years after resection...
July 2001: Hepato-gastroenterology
https://read.qxmd.com/read/9577040/-palliative-treatment-of-pancreatic-adenocarcinoma
#25
REVIEW
A Guglielmi, G De Manzoni, R Girlanda, M Frameglia, C Cordiano
Carcinoma of the pancreas is the fourth leading cause of cancer related death in Western Countries. The 5-year survival for resectable tumors is 15-25%, while patients with unresectable neoplasms survive a median of 7 months. Only 30% of carcinomas of the head of pancreas and 10% of the body and tail are resectable for cure. Therefore, palliation of symptoms, namely obstructive jaundice, duodenal obstruction and pain, involve 80-90% of cases. Jaundice is frequent in tumors of the head. Palliative biliary decompression can be achieved by non surgical methods-endoscopically placed endoprostheses or percutaneous biliary drainage- or surgically...
September 1997: Annali Italiani di Chirurgia
https://read.qxmd.com/read/9372373/carcinoma-of-the-pancreas-resection-outcome-at-the-university-hospital-kuala-lumpur
#26
JOURNAL ARTICLE
M D Shahrudin
BACKGROUND: Recent studies have demonstrated a reduction in the morbidity and mortality of pancreatic resection and improvement in the actuarial 5-year survival for patients with resected ductal adenocarcinoma. We reviewed the clinico-pathological characteristics of patients who underwent resection with curative intent for ductal adenocarcinoma of the pancreas between 1980 and 1993. METHODS: Resection with curative intent was performed on 236 of 1368 patients (17%) with pancreatic cancer admitted to the University Hospital Kuala Lumpur, Malaysia...
July 1997: International Surgery
https://read.qxmd.com/read/9177532/duodenal-obstruction-secondary-to-a-metastasis-from-an-adenocarcinoma-of-the-cecum-a-case-report
#27
JOURNAL ARTICLE
J J Sebastián, R Zaragozano, J Vicente, O Gallego, J M Trufero
Metastatic tumors to the gastrointestinal tract are rare; the stomach and small bowel are the most common organs involved. Lung cancer, renal cell carcinoma, breast carcinoma, and malignant melanoma are the most common primary tumors metastatic to the duodenum. We report a metastasis to the duodenum from an adenocarcinoma of the cecum presenting as a duodenal obstruction 4.5 yr after the surgical resection of the primary tumor. The condition of the patient was temporarily controlled with the implantation of an endoduodenal metallic prosthesis as a palliative measure...
June 1997: American Journal of Gastroenterology
https://read.qxmd.com/read/8604907/long-term-survival-after-curative-resection-for-pancreatic-ductal-adenocarcinoma-clinicopathologic-analysis-of-5-year-survivors
#28
JOURNAL ARTICLE
K C Conlon, D S Klimstra, M F Brennan
OBJECTIVE: The authors reviewed the clinicopathologic characteristics of patients who underwent resection with curative intent for ductal adenocarcinoma of the pancreas between 1983 and 1989. SUMMARY BACKGROUND DATA: Recent studies have demonstrated a reduction in the morbidity and mortality of pancreatic resection and improvement in the actuarial 5-year survival for patients with resected ductal adenocarcinoma. METHODS: Resection with curative intent was performed on 118 of 684 patients (17%) with pancreatic cancer admitted to the authors' institution...
March 1996: Annals of Surgery
https://read.qxmd.com/read/8374871/neoadjuvant-chemoradiation-in-pancreatic-and-duodenal-carcinoma-a-phase-ii-study
#29
JOURNAL ARTICLE
R S Yeung, J L Weese, J P Hoffman, L J Solin, A R Paul, P F Engstrom, S Litwin, M J Kowalyshyn, B L Eisenberg
BACKGROUND: Low resectability rate and high locoregional recurrence are major factors contributing to the failure of surgical treatment for localized pancreatic adenocarcinoma. A Phase II study involving preoperative 5-fluorouracil (5-FU) and mitomycin C and radiation therapy was evaluated. METHODS: Thirty-one patients with biopsy-proven carcinoma (24, head of pancreas; 2, body; 5 duodenum) were treated with preoperative radiation therapy, 5040 cGy (180 cGy/fraction, 5 days/week), concurrent with 5-FU, 1000 mg/m2/day continuous infusion (days 2-5, 28-32) and mitomycin C 10 mg/m2 bolus (day 2)...
October 1, 1993: Cancer
https://read.qxmd.com/read/7952464/resection-for-cure-of-carcinoma-of-the-colon-directly-invading-the-duodenum-or-pancreatic-head
#30
JOURNAL ARTICLE
S A Curley, D B Evans, F C Ames
BACKGROUND: Approximately 10 percent of carcinomas of the colon and rectum adhere to adjacent organs or structures, which rarely include the duodenum or pancreas. STUDY DESIGN: To confirm the importance of aggressive operative management in patients with locally advanced carcinoma of the colon invading the duodenum or pancreatic head, we reviewed the medical records of 12 patients who underwent an extended resection for a right-sided carcinoma of the colon involving the duodenum or the pancreatic head, or both...
November 1994: Journal of the American College of Surgeons
https://read.qxmd.com/read/7549731/obstructive-jaundice-in-gastric-carcinoma-cause-site-and-relationship-to-the-primary-lesion
#31
JOURNAL ARTICLE
B H Lee, S Y Chin, S A Kim, K H Kim, Y S Do
OBJECTIVE: Obstructive jaundice is frequently present in patients with advanced gastric carcinoma. The purpose of this study was to assess the cause and preferential site of bile duct obstruction in patients with gastric carcinoma and to evaluate correlativity of biliary obstruction with the nature of the primary gastric lesion. METHODS: Cholangiographic findings of 54 patients with metastatic gastric carcinoma presenting with obstructive jaundice were reviewed retrospectively...
July 1995: Abdominal Imaging
https://read.qxmd.com/read/7308716/direct-metastatic-spread-of-right-colonic-adenocarcinoma-to-duodenum-barium-and-computed-tomographic-findings
#32
JOURNAL ARTICLE
R T Diamond, H M Greenberg, I F Boult
Contiguous involvement of the duodenum from primary right-sided colonic neoplasms is relatively uncommon. More rarely, metastatic involvement of the duodenum occurs after resection of a primary carcinoma of the right colon. Until recently, the radiological assessment of this pathologic process has been limited to barium gastrointestinal imaging techniques. Three cases of primary right colonic tumors metastasizing to the duodenum are presented, and barium studies are correlated with CT findings in 2 of these cases...
1981: Gastrointestinal Radiology
https://read.qxmd.com/read/6978900/endoscopic-diagnosis-of-duodenal-neoplasms-causing-upper-gastrointestinal-bleeding
#33
JOURNAL ARTICLE
P Sharon, R Stalnikovicz, D Rachmilewitz
Duodenal neoplasms are a rare and not often considered cause of massive upper gastrointestinal bleeding. During a 4-year period, 859 endoscopies in patients with upper gastrointestinal bleeding revealed a duodenal tumor to be the cause of bleeding in eight patients. Three patients had a primary duodenal neoplasm, two had metastatic involvement, and in three others pancreatic tumors had invaded the duodenum. In view of our findings, we recommend careful endoscopic scrutiny of all parts of the duodenum in patients with upper gastrointestinal bleeding especially when the cause of bleeding is not found in the esophagus, stomach, or duodenal bulb...
February 1982: Journal of Clinical Gastroenterology
https://read.qxmd.com/read/6347377/leiomyosarcoma-of-the-gastro-intestinal-tract-general-pattern-of-metastasis-and-recurrence
#34
REVIEW
Y T Lee
Clinically, epithelial cancers (squamous cell carcinoma and adenocarcinomas) metastasize primarily by the lymphatic route, while mesenchymal sarcomas more frequently enter the blood stream directly. Nevertheless metastatic involvement of regional nodes has been seen in 13% of patients with soft tissue sarcomas and in 7% of bone sarcomas at initial presentation (29). About one-third of the leiomyosarcomas of the gastro-intestinal tract developed metastasis and about 90% of the metastasis were intra-abdominal (45)...
June 1983: Cancer Treatment Reviews
https://read.qxmd.com/read/3809502/duodenal-neoplasms-role-of-ct
#35
JOURNAL ARTICLE
M C Farah, S Z Jafri, R E Schwab, D G Mezwa, I R Francis, S Noujaim, C Kim
In a retrospective study of 14 cases of duodenal neoplasms evaluated by computed tomography (CT), there were four primary adenocarcinomas of the duodenum, one lymphoma, five metastatic carcinomas, two duodenal lipomas, one villous adenoma, and one leiomyoma. The CT findings were diagnostic in patients with duodenal lipomas. In 11 cases, a primary origin of the mass was clearly identifiable in the duodenum. Thickening of the bowel wall, tumor necrosis, ulceration, and intraluminal defects were common. The relationship of the masses to adjacent structures was clearly shown on CT scans...
March 1987: Radiology
https://read.qxmd.com/read/3608549/the-superior-mesenteric-artery-fat-plane-is-obliteration-pathognomonic-of-pancreatic-carcinoma
#36
JOURNAL ARTICLE
D G Mitchell, M C Hill, R Cooper, E Bury, S Brick, P Lane, C Magal, R Roberts
Obliteration of the fat plane surrounding the superior mesenteric artery has been described as characteristic of pancreatic carcinoma. To determine the specificity of this and other computed tomography findings in the pancreas and peripancreatic region, scans of 86 patients were reviewed without clinical history. Diagnoses included pancreatitis (26 patients); pancreatic adenocarcinoma (14 patients); lymphoma (17 patients); metastatic nonpancreatic carcinoma (14 patients); and normal findings (15 patients). Confluent adenopathy could not be reliably differentiated from a pancreatic mass except when adenopathy separated the common bile duct from the duodenum...
July 1987: Journal of Computed Tomography
https://read.qxmd.com/read/2657848/ct-of-the-stomach-and-duodenum
#37
REVIEW
J C Scatarige, D J DiSantis
CT has become an important tool in the diagnosis and management of diseases that affect the stomach and duodenum. By depicting the bowel lumen, wall, and extramural structures, CT can provide unique information that complements standard air contrast radiography and endoscopy. Proper scanning methods and knowledge of normal anatomy are necessary for optimal results. We utilize the gas contrast technique for organ-specific examination in patients with known or suspected gastroduodenal disease. Gastric adenocarcinoma is an important indication for CT evaluation...
July 1989: Radiologic Clinics of North America
https://read.qxmd.com/read/2650006/pancreatoduodenectomy-with-pyloric-preservation-for-carcinoma-of-the-pancreas-a-cautionary-note
#38
REVIEW
K W Sharp, C B Ross, S A Halter, J G Morrison, W O Richards, L F Williams, J L Sawyers
Radical pancreatoduodenectomy for treatment of pancreatic carcinoma has been the surgical standard of care for the past four decades. The recent popularization of pylorus-sparing pancreatoduodenectomy to treat benign pancreatic disease, because of its decreased morbidity and long-term nutritional consequences, has led to the use of this procedure in cases of pancreatic carcinoma. We report recent experience with three patients with pancreatic carcinoma in whom pyloric preservation would have compromised the potential chance for curative resection or compromised palliation because of occult spread of tumor to a region not resected with this new operative approach...
May 1989: Surgery
https://read.qxmd.com/read/1608975/a-metastatic-nude-mouse-model-of-human-pancreatic-cancer-constructed-orthotopically-with-histologically-intact-patient-specimens
#39
JOURNAL ARTICLE
X Fu, F Guadagni, R M Hoffman
Pancreatic cancer is one of the most intractable and least understood of all human cancers. Pancreatic cancers is the fourth-leading cause of cancer-related mortality in the United States with less than 2% of the patients surviving for 5 yr. In an effort to help develop more effective treatment modalities for pancreatic cancer and improve detection, we report an animal model for individual human pancreatic-cancer patients. The model involves orthotopic transplantation of histologically intact pancreatic-cancer specimens to the nude-mouse pancreas, which can result in models that resemble the clinical picture including (i) extensive local tumor growth, (ii) extension of the locally growing human pancreatic cancer to the nude-mouse stomach and duodenum, (iii) metastases of the human pancreatic tumor to the nude-mouse liver and regional lymph nodes, and (iv) distant metastases of the human pancreatic tumor to the nude-mouse adrenal gland, diaphragm, and mediastinal lymph nodes...
June 15, 1992: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/1415098/metastatic-tumors-to-the-upper-gastrointestinal-tract-endoscopic-experience
#40
JOURNAL ARTICLE
S C Kadakia, A Parker, L Canales
Metastatic tumors to the upper gastrointestinal tract were identified by esophagogastroduodenoscopy in 14 patients. Malignant melanoma, breast cancer, and lung cancer were the most common primary cancers in four, three, and three patients, respectively. Osteogenic sarcoma, renal cell carcinoma, Meckel cell carcinoma of the skin, and germ-cell tumor were the primary cancer in the remaining four. The esophagus was involved in three patients, the stomach in 13, duodenum in four, and papilla of Vater in one. Upper gastrointestinal bleeding and anemia were the most common presenting features...
October 1992: American Journal of Gastroenterology
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