Zhengkai Wei, Qinqin Jin, Wei Liu, Tingting Liu, Kaifeng He, Zha Jin, Meiyi Chen, Yuqian Jiang, Yuxiao Qian, Hongrong Hong, Dezhi Zhang, Quan Liu, Zhengtao Yang, Qianyong Li
Gliotoxin (GT) belongs to the epipolythiodioxopiperazine (ETP) family, which is considered a crucial virulence determinant among the secondary metabolites produced by Aspergillus fumigatus. The metabolites are commonly found in food and feed, contributing to the invasion and immune escape of Aspergillus fumigatus, thereby posing a significant threat to the health of livestock, poultry, and humans. Heterophil extracellular traps (HETs), a novel form of innate immune defense, have been documented in the chicken's innate immune systems for capturing and eliminating invading microbes...
April 4, 2024: Poultry Science