Sana Mahtab, Dianna M Blau, Zachary J Madewell, Ikechukwu Ogbuanu, Julius Ojulong, Sandra Lako, Hailemariam Legesse, Joseph S Bangura, Quique Bassat, Inacio Mandomando, Elisio Xerinda, Fabiola Fernandes, Rosauro Varo, Samba O Sow, Karen L Kotloff, Milagritos D Tapia, Adama Mamby Keita, Diakaridia Sidibe, Dickens Onyango, Victor Akelo, Dickson Gethi, Jennifer R Verani, Gunturu Revathi, J Anthony G Scott, Nega Assefa, Lola Madrid, Hiwot Bizuayehu, Tseyon Tesfaye Tirfe, Shams El Arifeen, Emily S Gurley, Kazi Munisul Islam, Muntasir Alam, Mohammad Zahid Hossain, Ziyaad Dangor, Vicky L Baillie, Martin Hale, Portia Mutevedzi, Robert F Breiman, Cynthia G Whitney, Shabir A Madhi
BACKGROUND: The Child Health and Mortality Prevention Surveillance (CHAMPS) Network programme undertakes post-mortem minimally invasive tissue sampling (MITS), together with collection of ante-mortem clinical information, to investigate causes of childhood deaths across multiple countries. We aimed to evaluate the overall contribution of pneumonia in the causal pathway to death and the causative pathogens of fatal pneumonia in children aged 1-59 months enrolled in the CHAMPS Network. METHODS: In this observational study we analysed deaths occurring between Dec 16, 2016, and Dec 31, 2022, in the CHAMPS Network across six countries in sub-Saharan Africa (Ethiopia, Kenya, Mali, Mozambique, Sierra Leone, and South Africa) and one in South Asia (Bangladesh)...
January 25, 2024: Lancet Child & Adolescent Health