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JOURNAL ARTICLE
Luis Silva, Luise Gomes da Motta, Lynn Eberly
OBJECTIVE: Tuberculosis (TB) is the second most deadly infectious disease globally, posing a significant burden in Brazil and its Amazonian region. This study focused on the "riverine municipalities" and hypothesizes the presence of TB clusters in the area. We also aimed to train a machine learning model to differentiate municipalities classified as hot spots vs. non-hot spots using disease surveillance variables as predictors. METHODS: Data regarding the incidence of TB from 2019 to 2022 in the riverine town was collected from the Brazilian Health Ministry Informatics Department...
2024: Brazilian Journal of Epidemiology
#22
JOURNAL ARTICLE
Julia Lopes Garrafa, Amanda Dantas-Silva, Fernanda Garanhani Surita, José Paulo de Siqueira Guida, Diama Bhadra Vale, Marina de Campos Brandão, Alberto Trapani, Roxana Knobel
OBJECTIVE: This study examines maternal mortality among Brazilian indigenous women from 2015 to 2021, contrasting their causes of death with non-indigenous women. METHODS: An observational study utilizing Ministry of Health data analyzed maternal deaths' characteristics, comparing indigenous and non-indigenous groups based on death certificates and live-birth records. Variables included age, region, location, time, and cause of death. Maternal mortality ratios (MMR) were calculated with linear regression and outliers identified with Grubbs test...
May 15, 2024: International Journal of Gynaecology and Obstetrics
#23
JOURNAL ARTICLE
Faisal Khalaf Alanazi, Samuel Lapkin, Luke Molloy, Jenny Sim
BACKGROUND: Safety culture is known to influence patient outcomes, but the relationship between nursing units' safety cultures and the development of pressure injuries in acute care hospitals is unclear. Pressure injuries are a nursing-sensitive patient outcome and are widely considered preventable. OBJECTIVE: To examine the impact of unit safety culture, nursing unit characteristics, and missed care on pressure injury rates in Saudi Arabian hospitals. DESIGN: A multi-center cross-sectional study was conducted between August and November 2021 and compared to secondary data on the incidence of pressure injuries...
December 2023: International journal of nursing studies advances
#24
Jorge L Cañari-Casaño, Valerie A Paz-Soldan, Andres G Lescano, Amy C Morrison
BACKGROUND: Dengue poses a significant public health challenge in Peru and other endemic countries worldwide. While severe dengue is known to be associated with secondary infection at the individual level, the factors that elevate the risk of severe dengue at the population level remain poorly understood. This study leverages over 16 years of secondary data from a Peruvian dengue surveillance system to assess which type of serotype-specific circulation is associated with an increased risk of cumulative incidence of severe dengue or dengue with warning signs (SD-DWS)...
May 3, 2024: medRxiv
#25
JOURNAL ARTICLE
Tingling Xu, Wenlan Dong, Jinli Liu, Peng Yin, Zhihui Wang, Lei Zhang, Maigeng Zhou
BACKGROUND: Parkinson's disease (PD) has become a public health concern with global ageing. However, comprehensive assessments of the temporal and geographical trend of PD disease burden in China remain insufficient. This study aimed to examine the burden of PD by age, gender, and geographical region in China during 1990-2021. METHODS: Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021, we analysed the incidence, prevalence, mortality, and DALY burden of PD in 33 Chinese provinces/regions...
May 2024: The Lancet Regional Health. Western Pacific
#26
JOURNAL ARTICLE
Andrew Anglemyer, Xiaoyun Ren, Charlotte Gilkison, Zoe Kumbaroff, Julie Morgan, Kara DuBray, Audrey Tiong, Arthur Reingold, Tony Walls
BACKGROUND: In Aotearoa New Zealand (NZ) PCV7 was introduced in 2008, then PCV10 in 2011 and PCV13 in 2014. In 2017 PCV10 was re-introduced, replacing PCV13. In the present study, we investigate the resultant rapidly changing invasive pneumococcal disease (IPD) epidemiology. METHODS: We compare the IPD incidence rate ratio (IRR) in NZ (2022 versus 2020) with other countries, and describe the IPD epidemiology (including trends in overall IPD and serotype 19A, and antimicrobial resistance) within NZ...
May 2024: The Lancet Regional Health. Western Pacific
#27
JOURNAL ARTICLE
Duygu Ünder, Cüneyd Enver, Muhammed Yasir Demirci, Yunus Emre Ayhan, Betül Özgan, Enes Emir İlerler, Betül Okuyan, Buket Ertürk Şengel, Derya Kocakaya, Uluhan Sili, Elif Tükenmez Tigen, Sait Karakurt, Volkan Korten, Mesut Sancar
OBJECTIVES: Drug-related problems (DRPs) result in serious problems among hospitalized patients, high rates of morbidity and mortality, and increased healthcare costs. This study aimed to identify DRPs by clinical pharmacist-led medication review in hospitalized probable patients with coronavirus disease-2019 (COVID-19) during the first wave of the COVID-19 pandemic. MATERIALS AND METHODS: This retrospective cross-sectional study was conducted at the COVID-19 inpatient services of a tertiary university hospital in Türkiye for 3 months (between March 2020 and June 2020) and included hospitalized confirmed or probable COVID-19 patients...
May 14, 2024: Turkish journal of pharmaceutical sciences
#28
JOURNAL ARTICLE
F F Losev, A G Nadtochii, T V Braylovskaya, M S Kotik
BACKGROUND: Restoring the integrity of the dentition with orthopedic structures should be carried out strictly according to indications, taking into account the condition of the supporting teeth and/or teeth limiting the defect. OBJECTIVE: To conduct a retrospective analysis of the results of orthopedic treatment of patients with shortened dentition according to clinical and radiological methods. MATERIALS AND METHODS: The material for the study was data from cone beam computed tomography (CBCT) of 126 patients with shortened dentition (most patients with the absence of a second molar, as well as the absence of the first and second molars), who sought a consultation about missing teeth in the orthopedic and surgical department of the Federal State Budgetary Institution National Medical Research Center TsNIISiCHLKh Ministry of Health of Russia...
2024: Stomatologii︠a︡
#29
REVIEW
Masashi Aoki, Rumiko Izumi, Naoki Suzuki
Sporadic inclusion body myositis (sIBM) is an intractable and progressive skeletal muscle disease of unknown etiology. Muscle biopsy typically reveals endomysial inflammation, invasion of mononuclear cells into non-necrotic fibers, and rimmed vacuoles, suggesting that inflammation and degeneration co-exist in the pathomechanism. According to a nationwide survey conducted by a research team of the Ministry of Health, Labor, and Welfare, the number of patients is increasing in Japan as well. The clinical progression shows a slow and chronic deterioration...
May 2024: Brain and Nerve, Shinkei Kenkyū No Shinpo
#30
RANDOMIZED CONTROLLED TRIAL
Christina Müllenmeister, Andrea Stoelting, Dominik Schröder, Tim Schmachtenberg, Simon Ritter, Iman El-Sayed, Sandra Steffens, Frank Klawonn, Sandra Klawitter, Stefanie Homann, Marie Mikuteit, Christoph Berg, Georg Behrens, Eva Hummers, Aisha Cook, Frank Müller, Alexandra Dopfer-Jablonka, Christine Happle
BACKGROUND: Post-COVID-19 syndrome (PCS; also known as "long COVID") is a relatively novel disease comprising physical, psychological, and cognitive complaints persisting several weeks to months after acute infection with SARS-CoV-2. Approximately 10% of patients with COVID-19 are affected by long-term symptoms. However, effective treatment strategies are lacking. The ErgoLoCo (Occupational Therapy [Ergotherapie] for Long COVID) study was designed to develop and evaluate a novel occupational therapy (OT) concept of online delivery of therapy for long COVID...
May 13, 2024: JMIR Research Protocols
#31
JOURNAL ARTICLE
Michel Kabamba Nzaji, Anselme Manyong Kapit, Kristen B Stolka, Shanice Fezeu Meyou, Charlie K Kasendue, Melissa Dahlke, Robert T Perry, Reena H Doshi, Brooke Noel Aksnes, Richard R Luce, Stephane Hans Bateyi Mustafa, Crispin Kazadi Mwina-Ngoie, Cikomola Mwana Wa Bene Aimé, Pia D M MacDonald, Claire J Standley
BACKGROUND: Low levels of COVID-19 vaccination coverage in many countries prompted the use of rapid assessments to characterize barriers to vaccination and identify corrective measures. The World Health Organization recommended the use of intra-action reviews (IARs) to identify best practices, gaps, and lessons learned to make real-time improvements to the COVID-19 vaccination response. OBJECTIVE: The Democratic Republic of the Congo (DRC) implemented a national IAR in July 2021 that was poorly attended by the provincial health level, where vaccination activities are planned and implemented...
2024: Journal of Multidisciplinary Healthcare
#32
JOURNAL ARTICLE
SongAm Lee, JunSeok Kim, Michael Ji, HyeongJu Moon, WooSurng Lee
BACKGROUND: Antithrombin is a small plasma glycoprotein synthesized in the liver that belongs to the serpin family of serine protease inhibitors and inactivates several enzymes in the coagulation pathway. It plays a leading major factor on coagulation pathway, therefore administration of antithrombin is essential to treat serious clinical conditions such as disseminated intravascular coagulation (DIC). Despite the theoretical benefits of antithrombin supplementation, the optimal antithrombin activity for heparin efficacy and the benefits of antithrombin supplementation in various disease entities are not yet fully understood...
April 23, 2024: Annals of Palliative Medicine
#33
REVIEW
Elyad M Davidson
The number of medical cannabis licenses in Israel is increasing persistently (over 120,000 approved licenses in October 2022), reaching about 1.5% of adult population. Medical cannabis products are available in two main forms: inflorescence (administered by smoking or evaporation) and cannabis oil (administered sub-lingually). Data from the Israel ministry of health, regarding the split between these forms, show a major preference for inflorescence products over cannabis oils. This preference is increasing over time...
May 2024: Harefuah
#34
JOURNAL ARTICLE
Gonzalo Borrego-Yaniz, Lourdes Ortiz-Fernández, Adela Madrid-Paredes, Martin Kerick, José Hernández-Rodríguez, Sarah L Mackie, Augusto Vaglio, Santos Castañeda, Roser Solans, Jaume Mestre-Torres, Nader Khalidi, Carol A Langford, Steven Ytterberg, Lorenzo Beretta, Marcello Govoni, Giacomo Emmi, Marco A Cimmino, Torsten Witte, Thomas Neumann, Julia Holle, Verena Schönau, Gregory Pugnet, Thomas Papo, Julien Haroche, Alfred Mahr, Luc Mouthon, Øyvind Molberg, Andreas P Diamantopoulos, Alexandre Voskuyl, Thomas Daikeler, Christoph T Berger, Eamonn S Molloy, Daniel Blockmans, Yannick van Sleen, Mark Iles, Louise Sorensen, Raashid Luqmani, Gary Reynolds, Marwan Bukhari, Shweta Bhagat, Norberto Ortego-Centeno, Elisabeth Brouwer, Peter Lamprecht, Sebastian Klapa, Carlo Salvarani, Peter A Merkel, María C Cid, Miguel A González-Gay, Ann W Morgan, Javier Martin, Ana Márquez
BACKGROUND: Giant cell arteritis is an age-related vasculitis that mainly affects the aorta and its branches in individuals aged 50 years and older. Current options for diagnosis and treatment are scarce, highlighting the need to better understand its underlying pathogenesis. Genome-wide association studies (GWAS) have emerged as a powerful tool for unravelling the pathogenic mechanisms involved in complex diseases. We aimed to characterise the genetic basis of giant cell arteritis by performing the largest GWAS of this vasculitis to date and to assess the functional consequences and clinical implications of identified risk loci...
May 8, 2024: Lancet Rheumatology
#35
JOURNAL ARTICLE
Julie M Buser, Marie Laetitia Ishimwe Bazakare, Gerard Kaberuka, Ella August, Madeleine Mukeshimana, Rachel Gray, Diomede Ntasumbumuyange, Faelan E Jacobson-Davies, Tamrat Endale, Olive Tengera, Yolanda R Smith
BACKGROUND: Addressing the gap between research and practice is crucial for enhancing reproductive healthcare outcomes. In Rwanda and other low- and middle-income countries, bolstering health researchers' implementation science (IS) capacity is essential. We present a pre-post-intervention study assessing the influence of an intensive IS training program on Rwandan reproductive health researchers' perceived IS knowledge and self-efficacy in applying IS in their own research. METHODS: To introduce IS principles, we held a one-day training for a diverse cohort of 25 sexual and reproductive health researchers in Rwanda...
May 7, 2024: Sexual & Reproductive Healthcare: Official Journal of the Swedish Association of Midwives
#36
JOURNAL ARTICLE
Nourit Houminer Klepar, Nadav Davidovitch, Keren Dopelt
Emotional eating, the act of consuming food to cope with negative emotions rather than responding to hunger cues, can lead to overeating in an attempt to regulate and alleviate these emotions. This study aimed to assess emotional eating among college students in Israel, specifically during times of war, which present unique and heightened stressors that accumulate on top. A total of 575 participants from the Ashkelon Academic College completed an online questionnaire examining background information, stress levels, and emotional eating symptoms...
April 27, 2024: Foods (Basel, Switzerland)
#37
JOURNAL ARTICLE
Mariane de Mello Fontanelli, Lais Duarte Batista, Angela Martinez-Arroyo, Dariush Mozaffarian, Renata Micha, Marcelo Macedo Rogero, Regina Mara Fisberg, Flavia Mori Sarti
The challenges in the characterization of the nutritional quality of grain foods comprise obstacles to public health actions toward promotion of healthier grain-based foods. The present study investigated how carbohydrate metrics related to glycemic index (GI), glycemic load (GL), and warning labels of grain foods consumed by individuals living in São Paulo, Brazil. Information on intake of grain foods at individual level was obtained using 24 h recalls within a cross-sectional population-based survey conducted in 2015...
April 24, 2024: Foods (Basel, Switzerland)
#38
JOURNAL ARTICLE
Collins Ankunda, Stuart Martin Kanyesigye, Susan Nakubulwa, Brendah Kyomuhangi, Jakob Cramer, Enrique Chacon-Cruz, Sue Ann Costa Clemens, Ralf Clemens
INTRODUCTION: Unrecognized Ebola Virus Disease (EVD) can lead to multiple chains of transmissions if the first caretakers are not trained and prepared. This study aimed to assess healthcare workers (HCWs) preparedness in private hospitals located in Kampala, to detect, respond and prevent EVD. METHODOLOGY: A descriptive cross-sectional study was carried out among HCWs in direct clinical care provision in four private hospitals, and in one Ebola Treatment Unit (ETU) using a self-administered questionnaire from March to June 2020...
April 30, 2024: Journal of Infection in Developing Countries
#39
JOURNAL ARTICLE
Chelsea Elkins, Sandra Kokera, Phiona Vumbugwa, Jacqueline Gavhera, Kathleen M West, Katherine Wilson, Batsirai Makunike-Chikwinya, Lewis Masimba, Marrianne Holec, Scott Barnhart, Sulemana Matinu, Beatrice Wassuna, Caryl Feldacker
In Zimbabwe, the ZAZIC consortium employs two-way, text-based (2wT) follow-up to strengthen post-operative care for voluntary medical male circumcision (VMMC). 2wT scaled nationally with evidence of client support and strengthened follow-up. However, 2wT uptake among healthcare providers remains suboptimal. Understanding the gap between mobile health (mHealth) potential for innovation expansion and scale-up realization is critical for 2wT and other mHealth innovations. Therefore, we conducted an exploratory qualitative study with the objective of identifying 2wT program strengths, challenges, and suggestions for scale up as part of routine VMMC services...
2024: PloS One
#40
JOURNAL ARTICLE
Samah Hayek, Joseph Levy, Galit Shaham, Noa Dagan, Danielle Serby, Hadar Duskin-Bitan, Adva Yarden, Cátia Ferreira, Idit Livnat, Sabada Dube, Sylvia Taylor, Sudhir Venkatesan, Ran D Balicer, Doron Netzer, Alon Peretz
INTRODUCTION: AZD7442 is a combination of two neutralizing antibodies (tixagevimab/cilgavimab) with demonstrated efficacy in reducing the risk of symptomatic coronavirus disease 2019 (COVID-19) among individuals at high risk of severe COVID-19 ≤ 6 months after administration. On February 15, 2022, the Israeli Ministry of Health (IMoH) authorized the administration of 300 mg AZD7442 as pre-exposure prophylaxis (PrEP) against severe acute respiratory syndrome coronavirus 2 infection among immunocompromised individuals aged ≥ 12 years...
May 10, 2024: Infectious Diseases and Therapy
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