Marco Bergamini, Alberto Dalla Volta, Carlotta Palumbo, Stefania Zamboni, Luca Triggiani, Manuel Zamparini, Marta Laganà, Luca Rinaudo, Nunzia Di Meo, Irene Caramella, Roberto Bresciani, Francesca Valcamonico, Paolo Borghetti, Andrea Guerini, Davide Farina, Alessandro Antonelli, Claudio Simeone, Gherardo Mazziotti, Alfredo Berruti
BACKGROUND: Among its extragonadal effects, follicle-stimulating hormone (FSH) has an impact on body composition and bone metabolism. Since androgen deprivation therapy (ADT) has a profound impact on circulating FSH concentrations, this hormone could potentially be implicated in the changes of fat body mass (FBM), lean body mass (LBM), and bone fragility induced by ADT. The objective of this study is to correlate FSH serum levels with body composition parameters, bone mineral density (BMD), and bone turnover markers at baseline conditions and after 12 months of ADT...
April 24, 2024: ELife