Fuqiang Pan, Wanzhen Fu, Bochao Zhang, Mengdi Han, Huihui Xie, Qing Yi, Wei Qian, Jiankun Cui, Meng Cao, Yanqiuhong Li, Yuke Jia, Fugui Fang, Yinghui Ling, Yunsheng Li, Ya Liu
Luteinizing hormone (LH) and follicle-stimulating hormone (FSH) play key roles in regulating testosterone secretion and spermatogenesis in male mammals, respectively, and they maintain the fertility of male animals by binding to their corresponding receptors. We designed and prepared a recombinant LH receptor (LHR) subunit vaccine and a recombinant FSH receptor (FSHR) subunit vaccine and used male Sprague Dawley (SD) rats as a model to examine their effects on testicular development, spermatogenesis, and testosterone secretion in prepubertal and pubertal mammals...
April 15, 2024: Veterinary Sciences