Mads Brix Kronborg, Maria Hee Jung Park Frausing, Jerzy Malczynski, Sam Riahi, Jens Haarbo, Katja Fiedler Holm, Charlotte Ellen Larroudé, Andi Eie Albertsen, Lene Svendstrup, Ulrik Hintze, Ole Dyg Pedersen, Ulla Davidsen, Thomas Fischer, Jens Brock Johansen, Jens Kristensen, Christian Gerdes, Jens Cosedis Nielsen
BACKGROUND AND AIMS: High percentages of atrial pacing have been associated with an increased risk of atrial fibrillation. This study is aimed at evaluating whether atrial pacing minimization in patients with sinus node dysfunction reduces the incidence of atrial fibrillation. METHODS: In a nationwide, randomized controlled trial, 540 patients with sinus node dysfunction and an indication for first pacemaker implantation were assigned to pacing programmed to a base rate of 60 bpm and rate-adaptive pacing (DDDR-60) or pacing programmed to a base rate of 40 bpm without rate-adaptive pacing (DDD-40)...
October 21, 2023: European Heart Journal