Richard J Odosso, Lorene Petta
INTRODUCTION: The lifetime prevalence for development of Posttraumatic Stress Disorder (PTSD) among military combat veterans has been estimated to be as high as 17%, or more than double the national average. The stellate ganglion block (SGB) has been proposed as a PTSD treatment modality that may potentially affect positive change in the attitude of a service member (SM) toward mental health treatment, lead to improved clinical outcomes, promote the likelihood of a return to a productive job performance, and decrease the economic burden of PTSD treatment on the Department of Defense...
November 26, 2020: Military Medicine
Cecelia Rose Lee-Hauser, Richard M Schein, Vince J Schiappa, Alison L Pruziner, Dave Tostenrude, Kristine E Goedhard, Leif M Nelson, Mark R Schmeler
INTRODUCTION: Although many studies report the impact of adaptive sports and recreation on quality of life for people with disabilities across several age groups, few have focused on the Veteran population. The purpose of this study was to establish a baseline of common characteristics of the Veteran population that participated in the National Veterans Wheelchair Games (NVWG) in 2017 and 2018, including their perception on how their participation is associated with function and social factors...
November 26, 2020: Military Medicine
Jordan Gisseman, Tara Fletcher, Abigail Schmolze, Devin Cooper, James Aden, Callie Cox-Bauer
INTRODUCTION: Perinatal and postpartum depression are common, affecting 13% to 24% of pregnant women through the first year postpartum. Depression screening is recommended by the American College of Obstetrics and Gynecology as an effective and low-cost intervention to improve patient outcomes; however, no nationwide screening rate is reported in the literature. This study was designed to assess the rate and effectiveness of screening in a major military medical center. MATERIALS AND METHODS: Institutional review board (IRB) approval was obtained before beginning the study...
November 26, 2020: Military Medicine
Atik Kulakli, Ivanna Shubina
BACKGROUND: Mobile apps are viewed as a promising opportunity to provide support for patients who have posttraumatic stress disorder (PTSD). The development of mobile technologies and apps shows similar trends in PTSD treatment. Therefore, this emerging research field has received substantial attention. Consequently, various research settings are planned for current and further studies. OBJECTIVE: The aim of this study was to explore the scientific patterns of research domains related to mobile apps and other technologies for PTSD treatment in scholarly publications, and to suggest further studies for this emerging research field...
November 26, 2020: JMIR MHealth and UHealth
Lana M Brown, Linda M Sawyer, Shelly Y Lensing, Tanya Taylor, Melinda M Bopp, Ileina Ferrier, Dennis H Sullivan
PURPOSE: To evaluate the effectiveness of an evidence-based 12-week Tai Chi course designed to improve balance and physical function in a population of older veterans. METHODS: Community dwelling veterans of all ages with gait and balance problems were invited to participate in the Tai Chi program. Participants completed the Berg Balance Scale (BBS), the Timed Up and Go (TUG) test, and the Falls Efficacy Scale-International (FES-I) at baseline and again at the end of the program...
November 26, 2020: Nursing Forum
Milena D Zirovich, Sanjog S Pangarkar, Christina Manh, Lucia Chen, Sitaram Vangala, David A Elashoff, Ifeoma Stella Izuchukwu
INTRODUCTION: Botulinum toxin type A (BoNT/A) is an approved treatment for chronic migraine and has been shown to be effective in reducing number, days, and severity of headache in other headache disorders. Whether botulinum toxin is a safe and effective treatment specifically for post-traumatic headache (PTH), however, is unknown. This study sought to determine whether treatment with BoNT/A improved symptoms of PTH in military veterans. MATERIALS AND METHODS: Forty subjects with PTH were randomized to receive treatment of either BoNT/A or a saline placebo...
November 26, 2020: Military Medicine
Ryan M Leone, Zenobia Homan, Antonin Lelong, Lutz Bandekow, Martin Bricknell
INTRODUCTION: A number of organizations publish comparisons of civilian health systems between countries. However, the authors were unable to find a global, systematic, and contemporary analysis of military healthcare systems. Although many databases exist for comparing national healthcare systems, the only such compilation of information for military medical systems is the Military Medical Almanac. A thorough review of the Almanac was conducted to understand the quality of information provided in each country's profile and to develop a framework for comparing between countries...
November 26, 2020: Military Medicine
Teresa C Fox, Connie Clabots, Stephen B Porter, Tricia Bender, Paul Thuras, Aylin Colpan, Jessica Boettcher, James R Johnson
Background: Although intestinal colonization precedes most extraintestinal Escherichia coli infections, colonization-promoting factors are incompletely understood. We compared within-household E. coli colonization patterns with host and bacterial traits. Methods: Twenty-two veterans with a clinical E. coli isolate and their 46 human and animal household members underwent longitudinal fecal sampling. Distinct E. coli strains were characterized for phylogenetic background, virulence genes, antibiotic resistance, and colonization behaviors...
November 2020: Open Forum Infectious Diseases
Mark Wheeler, Nicholas R Cooper, Leanne Andrews, Jamie Hacker Hughes, Marie Juanchich, Tim Rakow, Sheina Orbell
The authors confirm that all ongoing and related trials for this intervention are registered. The studies reported in this manuscript are registered as clinical trials at ISRCTN: Pilot ID- ISRCTN15325073 RCT ID- ISRCTN59395217.
2020: PloS One
(no author information available yet)
No abstract text is available yet for this article.
November 27, 2020: MMWR. Morbidity and Mortality Weekly Report
Ericka M Sohlberg, I-Chun Thomas, Jaden Yang, Kristopher Kapphahn, Kyla N Velaer, Mary K Goldstein, Todd H Wagner, Glenn M Chertow, James D Brooks, Chirag J Patel, Manisha Desai, John T Leppert
BACKGROUND: Estimates of overall patient health are essential to inform treatment decisions for patients diagnosed with cancer. The authors applied XWAS methods, herein referred to as "laboratory-wide association study (LWAS)", to evaluate associations between routinely collected laboratory tests and survival in veterans with prostate cancer. METHODS: The authors identified 133,878 patients who were diagnosed with prostate cancer between 2000 and 2013 in the Veterans Health Administration using any laboratory tests collected within 6 months of diagnosis (3,345,083 results)...
November 25, 2020: Cancer
Beth Aitchison, Alison Rushton, Paul Martin, Andrew Soundy, Nicola R Heneghan
INTRODUCTION: Sports participation has many physical and mental health benefits for individuals with a disability, including improved functionality and reduced anxiety. Despite this, a large proportion of individuals with a disability are inactive. This review will be the first to synthesise the literature on the experiences and perceived health benefits of sport participation for children, adolescents, adults, elite athletes and veterans with a disability. Investigation of these phenomena will enable an understanding of the positive aspects and benefits of sport participation specific to each population, which may help to improve participation rates and ultimately improve health through promotion of these benefits...
November 24, 2020: BMJ Open
Maher Roman, Ralph Clark, Najeeb Shirwany, Chizobam Ani, W Lawrence Beeson
BACKGROUND: Delay in primary care access for new patients to US Department of Veterans Affairs (VA) health care services has been a persistent problem. This article presents the evaluation of a quality improvement (QI) intervention that provided new patients with same-day primary care access. It involved redesign of an intake clinic (IC) through which new patients were initially seen and referred to primary care. The redesign included changes in clinic flow and reallocation of two full-time primary care providers (PCPs) from IC to their primary care teams...
October 24, 2020: Joint Commission Journal on Quality and Patient Safety
Nagapratap Ganta, Sehrish Sikandar, Sergio J Ruiz, Lubna A Nasr, Yaqub Nadeem Mohammed, Raquel Aparicio-Ugarriza, Victor Cevallos, Fei Tang, Jorge G Ruiz
OBJECTIVES: Determine the incidence rates of frailty among community-dwelling older veterans. DESIGN: Population-based retrospective cohort study. SETTING AND PARTICIPANTS: Veterans Health Administration Medical Center study included community-dwelling veterans 60 years and older with determinations of frailty from 2013 to 2014 and followed until September 2019. METHODS: A 31-item frailty index was generated at baseline and during each subsequent primary care encounters as a proportion of potential variables from electronic health record data...
November 15, 2020: Journal of the American Medical Directors Association
Shira Maguen, Brandon J Griffin, Laurel A Copeland, Daniel F Perkins, Cameron B Richardson, Erin P Finley, Dawne Vogt
BACKGROUND: Although research has shown that exposure to potentially traumatic and morally injurious events is associated with psychological symptoms among veterans, knowledge regarding functioning impacts remains limited. METHODS: A population-based sample of post-9/11 veterans completed measures of intimate relationship, health, and work functioning at approximately 9, 15, 21, and 27 months after leaving service. Moral injury, posttraumatic stress, and depression were assessed at ~9 months post-separation...
November 25, 2020: Psychological Medicine
Amy L Drapalski, Alicia Lucksted, Clayton H Brown, Li Juan Fang
OBJECTIVE: Ending Self-Stigma is a nine-session group intervention designed to teach individuals experiencing mental illness a set of tools and strategies to effectively deal with self-stigma and its effects. The authors examined the efficacy of Ending Self-Stigma with an active comparison group focused on general health and wellness education (the Health and Wellness intervention) in a cohort of veterans. METHODS: Veterans with serious mental illness (N=248) were randomly assigned to either the Ending Self-Stigma or the Health and Wellness intervention...
November 25, 2020: Psychiatric Services: a Journal of the American Psychiatric Association
Yi Guan, Chia-Hsin Cheng, Weifan Chen, Yingqi Zhang, Sophia Koo, Maxine Krengel, Patricia Janulewicz, Rosemary Toomey, Ehwa Yang, Rafeeque Bhadelia, Lea Steele, Jae-Hun Kim, Kimberly Sullivan, Bang-Bon Koo
Gulf War illness (GWI) refers to the multitude of chronic health symptoms, spanning from fatigue, musculoskeletal pain, and neurological complaints to respiratory, gastrointestinal, and dermatologic symptoms experienced by about 250,000 GW veterans who served in the 1991 Gulf War (GW). Longitudinal studies showed that the severity of these symptoms often remain unchanged even years after the GW, and these veterans with GWI continue to have poorer general health and increased chronic medical conditions than their non-deployed counterparts...
November 20, 2020: Brain Sciences
Michelle Lally, Philip Tsoukas, Christopher Halladay, Emily O'Neill, Stefan Gravenstein, James L Rudolph
OBJECTIVES: The COVID-19 pandemic presents an urgent need to investigate whether existing drugs can enhance or even worsen prognosis; metformin, a known mammalian target of rapamycin (m-TOR) inhibitor, has been identified as a potential agent. We sought to evaluate mortality benefit among older persons infected with SARS-CoV-2 who were taking metformin as compared to those who were not. DESIGN: Retrospective cohort study. SETTING AND PARTICIPANTS: 775 nursing home residents infected with SARS-CoV-2 who resided in one of the 134 Community Living Centers (CLCs) of the Veterans Health Administration (VHA) during March 1, 2020, to May 13, 2020, were included...
October 26, 2020: Journal of the American Medical Directors Association
Jason Theis, Katherine Hoops, Marisa Booty, Paul Nestadt, Cassandra Crifasi
INTRODUCTION: In the United States, firearm suicide represents a major cause of preventable, premature death among veterans. The purpose of this systematic review was to characterize the body of literature on veteran firearm suicide and identify areas for future research, which may facilitate the development of firearm suicide interventions in Veterans Health Administration (VHA) and non-Veterans Health Administration clinical settings. MATERIALS AND METHODS: All randomized controlled trials, quasi-experimental, naturalistic, observational, and case study designs published between January 1, 1990 and February 21, 2019 were included in our review...
November 24, 2020: Military Medicine
Praveen Surendran, Elena V Feofanova, Najim Lahrouchi, Ioanna Ntalla, Savita Karthikeyan, James Cook, Lingyan Chen, Borbala Mifsud, Chen Yao, Aldi T Kraja, James H Cartwright, Jacklyn N Hellwege, Ayush Giri, Vinicius Tragante, Gudmar Thorleifsson, Dajiang J Liu, Bram P Prins, Isobel D Stewart, Claudia P Cabrera, James M Eales, Artur Akbarov, Paul L Auer, Lawrence F Bielak, Joshua C Bis, Vickie S Braithwaite, Jennifer A Brody, E Warwick Daw, Helen R Warren, Fotios Drenos, Sune Fallgaard Nielsen, Jessica D Faul, Eric B Fauman, Cristiano Fava, Teresa Ferreira, Christopher N Foley, Nora Franceschini, He Gao, Olga Giannakopoulou, Franco Giulianini, Daniel F Gudbjartsson, Xiuqing Guo, Sarah E Harris, Aki S Havulinna, Anna Helgadottir, Jennifer E Huffman, Shih-Jen Hwang, Stavroula Kanoni, Jukka Kontto, Martin G Larson, Ruifang Li-Gao, Jaana Lindström, Luca A Lotta, Yingchang Lu, Jian'an Luan, Anubha Mahajan, Giovanni Malerba, Nicholas G D Masca, Hao Mei, Cristina Menni, Dennis O Mook-Kanamori, David Mosen-Ansorena, Martina Müller-Nurasyid, Guillaume Paré, Dirk S Paul, Markus Perola, Alaitz Poveda, Rainer Rauramaa, Melissa Richard, Tom G Richardson, Nuno Sepúlveda, Xueling Sim, Albert V Smith, Jennifer A Smith, James R Staley, Alena Stanáková, Patrick Sulem, Sébastien Thériault, Unnur Thorsteinsdottir, Stella Trompet, Tibor V Varga, Digna R Velez Edwards, Giovanni Veronesi, Stefan Weiss, Sara M Willems, Jie Yao, Robin Young, Bing Yu, Weihua Zhang, Jing-Hua Zhao, Wei Zhao, Wei Zhao, Evangelos Evangelou, Stefanie Aeschbacher, Eralda Asllanaj, Stefan Blankenberg, Lori L Bonnycastle, Jette Bork-Jensen, Ivan Brandslund, Peter S Braund, Stephen Burgess, Kelly Cho, Cramer Christensen, John Connell, Renée de Mutsert, Anna F Dominiczak, Marcus Dörr, Gudny Eiriksdottir, Aliki-Eleni Farmaki, J Michael Gaziano, Niels Grarup, Megan L Grove, Göran Hallmans, Torben Hansen, Christian T Have, Gerardo Heiss, Marit E Jørgensen, Pekka Jousilahti, Eero Kajantie, Mihir Kamat, AnneMari Käräjämäki, Fredrik Karpe, Heikki A Koistinen, Csaba P Kovesdy, Kari Kuulasmaa, Tiina Laatikainen, Lars Lannfelt, I-Te Lee, Wen-Jane Lee, Allan Linneberg, Lisa W Martin, Marie Moitry, Girish Nadkarni, Matt J Neville, Colin N A Palmer, George J Papanicolaou, Oluf Pedersen, James Peters, Neil Poulter, Asif Rasheed, Katrine L Rasmussen, N William Rayner, Reedik Mägi, Frida Renström, Rainer Rettig, Jacques Rossouw, Pamela J Schreiner, Peter S Sever, Emil L Sigurdsson, Tea Skaaby, Yan V Sun, Johan Sundstrom, Gudmundur Thorgeirsson, Tõnu Esko, Elisabetta Trabetti, Philip S Tsao, Tiinamaija Tuomi, Stephen T Turner, Ioanna Tzoulaki, Ilonca Vaartjes, Anne-Claire Vergnaud, Cristen J Willer, Peter W F Wilson, Daniel R Witte, Ekaterina Yonova-Doing, He Zhang, Naheed Aliya, Peter Almgren, Philippe Amouyel, Folkert W Asselbergs, Michael R Barnes, Alexandra I Blakemore, Michael Boehnke, Michiel L Bots, Erwin P Bottinger, Julie E Buring, John C Chambers, Yii-Der Ida Chen, Rajiv Chowdhury, David Conen, Adolfo Correa, George Davey Smith, Rudolf A de Boer, Ian J Deary, George Dedoussis, Panos Deloukas, Emanuele Di Angelantonio, Paul Elliott, Stephan B Felix, Jean Ferrières, Ian Ford, Myriam Fornage, Paul W Franks, Stephen Franks, Philippe Frossard, Giovanni Gambaro, Tom R Gaunt, Leif Groop, Vilmundur Gudnason, Tamara B Harris, Caroline Hayward, Branwen J Hennig, Karl-Heinz Herzig, Erik Ingelsson, Jaakko Tuomilehto, Marjo-Riitta Järvelin, J Wouter Jukema, Sharon L R Kardia, Frank Kee, Jaspal S Kooner, Charles Kooperberg, Lenore J Launer, Lars Lind, Ruth J F Loos, Abdulla Al Shafi Majumder, Markku Laakso, Mark I McCarthy, Olle Melander, Karen L Mohlke, Alison D Murray, Børge Grønne Nordestgaard, Marju Orho-Melander, Chris J Packard, Sandosh Padmanabhan, Walter Palmas, Ozren Polasek, David J Porteous, Andrew M Prentice, Michael A Province, Caroline L Relton, Kenneth Rice, Paul M Ridker, Olov Rolandsson, Frits R Rosendaal, Jerome I Rotter, Igor Rudan, Veikko Salomaa, Nilesh J Samani, Naveed Sattar, Wayne H-H Sheu, Blair H Smith, Nicole Soranzo, Timothy D Spector, John M Starr, Sylvain Sebert, Kent D Taylor, Timo A Lakka, Nicholas J Timpson, Martin D Tobin, Pim van der Harst, Peter van der Meer, Vasan S Ramachandran, Niek Verweij, Jarmo Virtamo, Uwe Völker, David R Weir, Eleftheria Zeggini, Fadi J Charchar, Nicholas J Wareham, Claudia Langenberg, Maciej Tomaszewski, Adam S Butterworth, Mark J Caulfield, John Danesh, Todd L Edwards, Hilma Holm, Adriana M Hung, Cecilia M Lindgren, Chunyu Liu, Alisa K Manning, Andrew P Morris, Alanna C Morrison, Christopher J O'Donnell, Bruce M Psaty, Danish Saleheen, Kari Stefansson, Eric Boerwinkle, Daniel I Chasman, Daniel Levy, Christopher Newton-Cheh, Patricia B Munroe, Joanna M M Howson
Genetic studies of blood pressure (BP) to date have mainly analyzed common variants (minor allele frequency > 0.05). In a meta-analysis of up to ~1.3 million participants, we discovered 106 new BP-associated genomic regions and 87 rare (minor allele frequency ≤ 0.01) variant BP associations (P < 5 × 10-8 ), of which 32 were in new BP-associated loci and 55 were independent BP-associated single-nucleotide variants within known BP-associated regions. Average effects of rare variants (44% coding) were ~8 times larger than common variant effects and indicate potential candidate causal genes at new and known loci (for example, GATA5 and PLCB3)...
November 23, 2020: Nature Genetics
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"